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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Lymphoma, AIDS-Related
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Accession:DOID:9000242 term browser browse the term
Definition:B-cell lymphoid tumors that occur in association with AIDS. Patients often present with an advanced stage of disease and highly malignant subtypes including BURKITT LYMPHOMA; IMMUNOBLASTIC LARGE-CELL LYMPHOMA; PRIMARY EFFUSION LYMPHOMA; and DIFFUSE, LARGE B-CELL, LYMPHOMA. The tumors are often disseminated in unusual extranodal sites and chromosomal abnormalities are frequently present. It is likely that polyclonal B-cell lymphoproliferation in AIDS is a complex result of EBV infection, HIV antigenic stimulation, and T-cell-dependent HIV activation.
Synonyms:exact_synonym: AIDS Associated Lymphoma;   AIDS-Associated Lymphomas;   AIDS-Related Lymphomas;   HIV Related Lymphoma;   HIV-Related Lymphomas
 narrow_synonym: AIDS-Related Primary Central Nervous System Lymphoma
 primary_id: MESH:D016483;   RDO:0006960
 xref: EFO:1000077;   EFO:1001365

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Lymphoma, AIDS-Related term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aicda activation induced cytidine deaminase disease_progression ISO RGD PMID:18090274 RGD:32716407 NCBI chrNW_004624860:4,912,938...4,927,846
Ensembl chrNW_004624860:4,912,656...4,926,634 		JBrowse link
G Csf2 colony stimulating factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:7680712 PMID:9817281 NCBI chrNW_004624733:40,039,127...40,041,294
Ensembl chrNW_004624733:40,039,414...40,041,294 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:12176798 NCBI chrNW_004624795:3,162,999...3,167,248
Ensembl chrNW_004624795:3,163,009...3,166,594 		JBrowse link
G Sdc1 syndecan 1 ISO protein:altered expression:tumor (human) RGD PMID:11157493 RGD:9743929 NCBI chrNW_004624738:2,920,154...2,938,035 JBrowse link
G Tfrc transferrin receptor treatment ISO RGD PMID:26325374 RGD:11062098 NCBI chrNW_004624730:61,282,650...61,313,487
Ensembl chrNW_004624730:61,285,334...61,313,550 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14229
    disease of anatomical entity 13931
      hematopoietic system disease 3344
        leukocyte disease 1160
          B-cell lymphoma 303
            Lymphoma, AIDS-Related 5
Path 2
Term Annotations click to browse term
  disease 14229
    disease of cellular proliferation 6846
      cancer 5021
        organ system cancer 4803
          immune system cancer 572
            lymphatic system cancer 572
              lymphoma 490
                non-Hodgkin lymphoma 416
                  B-cell lymphoma 303
                    Lymphoma, AIDS-Related 5
paths to the root