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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:glomerular filtration rate index
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Accession:CMO:0003628 term browser browse the term
Definition:This index is the first order rate constant, k(cl), which describes the clearance of an extracellular contrast agent (Gd-DTPA (gadopentetic acid), Gd-DOTA (gadoteric acid), or gadoterate meglumine (organoammonium salt of gadoteric acid) from renal cortex to outer medulla as calculated according to the following equation: k(cl)=(dc[medulla]/dt)/c[cortex]. The concentration in the cortex (predominantly blood signal) is compared to the concentration in the medulla (predominantly urine). The clearance of the contrast agent can serve as a marker for the glomerular filtration rate.
Synonyms:exact_synonym: K(cl)
 xref: PMID:10913720;   PMID:14561850


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Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        glomerular filtration rate 0
          calculated glomerular filtration rate 0
            glomerular filtration rate index 0
              multiregional glomerular filtration rate index 0
              regional glomerular filtration rate index 0
              renal perfusion index 0
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    renal/urinary measurement 250
      kidney measurement 133
        kidney physiological measurement 28
          calculated kidney physiological measurement 10
            glomerular filtration rate 0
              calculated glomerular filtration rate 0
                glomerular filtration rate index 0
                  multiregional glomerular filtration rate index 0
                  regional glomerular filtration rate index 0
                  renal perfusion index 0
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