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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:doxercalciferol
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Accession:CHEBI:4712 term browser browse the term
Definition:A hydroxy seco-steroid and synthetic vitamin D2 analogue that undergoes metabolic activation in vivo to form 1alpha,25-dihydroxyvitamin D2 (1alpha,25-(OH)2D2), a naturally occurring, biologically active form of vitamin D2. It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease.
Synonyms:exact_synonym: (1S,3R,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraene-1,3-diol
 related_synonym: 1alpha-Hydroxyergocalciferol;   1alpha-hydroxyvitamin D2;   Formula=C28H44O2;   InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1;   InChIKey=HKXBNHCUPKIYDM-CGMHZMFXSA-N;   SMILES=C1[C@]2([C@](/C(=C/C=C/3\\C([C@H](C[C@@H](C3)O)O)=C)/CC1)(CC[C@@]2([C@H](C)/C=C/[C@@H](C(C)C)C)[H])[H])C;   doxercalciferolum;   hectorol
 xref: CAS:54573-75-0;   DrugBank:DB06410;   Drug_Central:957;   KEGG:C08211;   KEGG:D01009;   PDBeChem:V2H;   PMID:12227689;   PMID:12834181;   PMID:17603751;   PMID:21155068;   PMID:21849802;   PMID:22123370;   PMID:23780943;   PMID:25774916;   PMID:28586017;   Wikipedia:Doxercalciferol


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Term Annotations click to browse term
  CHEBI ontology 19853
    role 19825
      biological role 19823
        provitamin 278
          doxercalciferol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19853
    subatomic particle 19851
      composite particle 19851
        hadron 19851
          baryon 19851
            nucleon 19851
              atomic nucleus 19851
                atom 19851
                  main group element atom 19797
                    p-block element atom 19797
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            organic molecule 19685
                              organic cyclic compound 19496
                                organic polycyclic compound 17262
                                  steroid 14717
                                    hydroxy steroid 14464
                                      hydroxy seco-steroid 2702
                                        vitamin D 2697
                                          doxercalciferol 0
paths to the root