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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:triforine
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Accession:CHEBI:9715 term browser browse the term
Definition:A member of the class of N-alkylpiperazines in which the two amino groups of piperazine are replaced by 1-formamido-2,2,2-trichloroethyl groups. A fungicide active against a range of diseases including powdery mildew, scab and rust.
Synonyms:exact_synonym: N,N'-[piperazine-1,4-diylbis(2,2,2-trichloroethane-1,1-diyl)]diformamide
 related_synonym: 1,4-Bis(1-formamido-2,2,2-trichloroethyl)piperazine;   1,4-Bis(2,2,2-trichloro-1-formamidoethyl)piperazine;   Biformylchlorazin;   Formula=C10H14Cl6N4O2;   Funginex;   InChI=1S/C10H14Cl6N4O2/c11-9(12,13)7(17-5-21)19-1-2-20(4-3-19)8(18-6-22)10(14,15)16/h5-8H,1-4H2,(H,17,21)(H,18,22);   InChIKey=RROQIUMZODEXOR-UHFFFAOYSA-N;   N,N'-(1,4-Piperazinediylbis(2,2,2-trichloroethylidene))bisformamide;   N,N'-(Piperazine-1,4-diylbis((trichloromethyl)methylene))diformamide;   SMILES=ClC(Cl)(Cl)C(NC=O)N1CCN(CC1)C(NC=O)C(Cl)(Cl)Cl
 xref: CAS:26644-46-2;   KEGG:C10960
 xref_mesh: MESH:C012591
 xref: PMID:1002932;   PMID:1267484;   PMID:15052559;   PMID:24122157;   PMID:2471555;   PMID:597629;   PMID:680740;   PMID:7821004;   PMID:890154;   PPDB:669;   Patent:EP0031454;   Patent:US3975527;   Pesticides:triforine;   Reaxys:626358


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triforine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO triforine binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        aetiopathogenetic role 19213
          allergen 17661
            triforine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organochalcogen compound 19264
                                organooxygen compound 19180
                                  carbon oxoacid 18666
                                    carboxylic acid 18663
                                      carboacyl group 17715
                                        univalent carboacyl group 17690
                                          carbamoyl group 17566
                                            carboxamide 17566
                                              formamides 1817
                                                triforine 1
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