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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:megestrol acetate
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Accession:CHEBI:6723 term browser browse the term
Definition:A steroid ester resulting from the formal condensation of the hydroxy group of megestrol with the carboxy group of acetic acid. It is an appetite stimulant used for the treatment of anorexia and cachexia. Also used for birth control and for the treatment of breast cancer.
Synonyms:exact_synonym: 6-methyl-3,20-dioxopregna-4,6-dien-17-yl acetate
 related_synonym: 17-Acetoxy-6-methylpregna-4,6-diene-3,20-dione;   17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione 17-acetate;   17alpha-Acetoxy-6-dehydro-6-methylprogesterone;   17alpha-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate;   6-Methyl-17alpha-acetoxypregna-4,6-diene-3,20-dione;   6-Methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate;   6-Methyl-6-dehydro-17alpha-acetoxyprogesterone;   6-Methyl-delta(sup 4,6)-pregnadien-17alpha-ol-3,20-dione acetate;   6-Methyl-delta(sup 6)-dehydro-17alpha-acetoxyprogesterone;   BDH 1298;   BDH1298;   Formula=C24H32O4;   InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23,15(2)25)28-16(3)26/h12-13,18-20H,6-11H2,1-5H3/t18-,19+,20+,22-,23+,24+/m1/s1;   InChIKey=RQZAXGRLVPAYTJ-GQFGMJRRSA-N;   Maygace;   Megace;   Megeron;   Megestat;   Megestil;   Megestin;   Niagestin;   Ovaban;   Ovarid;   Pallace;   SC-10363;   SC10363;   SMILES=[H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C;   Volidan;   magestin
 xref: Beilstein:1917291;   CAS:595-33-5;   DrugBank:DB00351;   KEGG:C08151;   KEGG:D00952;   LIPID_MAPS_instance:LMST02030118
 xref_mesh: MESH:D019290
 xref: PMCID:PMC7207385;   PMID:11986264;   PMID:27038209;   PMID:27218795;   PMID:27639080;   PMID:28986550;   PMID:29050522;   PMID:29095656;   PMID:29400904;   PMID:29442239;   PMID:29542279;   PMID:29581752;   PMID:30112227;   PMID:30157059;   PMID:31036192;   PMID:31359357;   PMID:31451262;   PMID:31462353;   PMID:31497435;   PMID:31961463;   PMID:32084501;   PMID:32122805;   PMID:32652300;   PMID:5320316;   Patent:GB870286;   Patent:US2891079;   Patent:US3356573;   Patent:US3400137;   Wikipedia:Megestrol_acetate


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Path 1
Term Annotations click to browse term
  CHEBI ontology 501
    role 501
      application 457
        pharmaceutical 452
          drug 452
            antineoplastic agent 324
              megestrol acetate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 501
    subatomic particle 501
      composite particle 501
        hadron 501
          baryon 501
            nucleon 501
              atomic nucleus 501
                atom 501
                  main group element atom 494
                    p-block element atom 494
                      carbon group element atom 483
                        carbon atom 482
                          organic molecular entity 482
                            heteroorganic entity 476
                              organochalcogen compound 430
                                organooxygen compound 428
                                  carbonyl compound 404
                                    ketone 48
                                      oxo steroid 23
                                        3-oxo steroid 21
                                          3-oxo-Delta(4) steroid 20
                                            megestrol 0
                                              megestrol acetate 0
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