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ONTOLOGY REPORT - ANNOTATIONS


Term:megestrol
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Accession:CHEBI:6722 term browser browse the term
Definition:A 3-oxo Delta(4)-steroid that is pregna-4,6-diene-3,20-dione substituted by a hydroxy group at position 17.
Synonyms:exact_synonym: 17-hydroxypregna-4,6-diene-3,20-dione
 related_synonym: 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione;   Formula=C22H30O3;   InChI=1S/C21H28O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h4-5,12,16-18,24H,6-11H2,1-3H3/t16-,17+,18+,19+,20+,21+/m1/s1;   InChIKey=JBVNBBXAMBZTMQ-CEGNMAFCSA-N;   SMILES=[H][C@]12CC[C@@]3(C)[C@@]([H])(CC[C@]3(O)C(C)=O)[C@]1([H])C=CC1=CC(=O)CC[C@]21C;   megestrolum
 xref: Beilstein:3164843 "Beilstein";   CAS:3562-63-8 "ChemIDplus";   DrugBank:DB00351;   KEGG:C07120;   KEGG:D08167
 xref_mesh: MESH:D008535
 xref: PMID:12161003 "Europe PMC";   Reaxys:3164843 "Reaxys";   Wikipedia:Megestrol


show annotations for term's descendants       view all columns           Sort by:
 
megestrol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gap43 growth associated protein 43 JBrowse link 11 58,624,198 58,717,916 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Ret ret proto-oncogene JBrowse link 4 150,202,170 150,249,196 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
megestrol acetate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Ahsa1 activator of Hsp90 ATPase activity 1 JBrowse link 6 111,296,168 111,304,224 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bcl11b BAF chromatin remodeling complex subunit BCL11B JBrowse link 6 131,834,097 131,927,251 RGD:6480464
G Cct6a chaperonin containing TCP1 subunit 6A JBrowse link 12 30,491,584 30,501,813 RGD:6480464
G Cldn1 claudin 1 JBrowse link 11 77,815,216 77,830,373 RGD:6480464
G Cldn4 claudin 4 JBrowse link 12 24,761,210 24,763,008 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:6480464
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:6480464
G Mmp8 matrix metallopeptidase 8 JBrowse link 8 5,768,808 5,777,741 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Ppia peptidylprolyl isomerase A JBrowse link 14 86,673,775 86,677,443 RGD:6480464
G Rab6a RAB6A, member RAS oncogene family JBrowse link 1 165,624,973 165,664,201 RGD:6480464
G Sf3a3 splicing factor 3a, subunit 3 JBrowse link 5 142,702,721 142,722,350 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            antineoplastic agent 16555
              megestrol 24
                megestrol acetate 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      ketone 15789
                                        oxyketone 8443
                                          alpha-oxyketone 8443
                                            alpha-hydroxy ketone 8443
                                              tertiary alpha-hydroxy ketone 8264
                                                megestrol 24
                                                  megestrol acetate 18
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.