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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:2,3-dimethoxynaphthalene-1,4-dione
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Accession:CHEBI:64215 term browser browse the term
Definition:A naphthoquinone that is 1,4-naphthoquinone bearing two methoxy substituents at positions 2 and 3. Redox-cycling agent that induces intracellular superoxide anion formation and, depending on the concentration, induces cell proliferation, apoptosis or necrosis. Used to study the role of ROS in cell toxicity, apoptosis, and necrosis.
Synonyms:exact_synonym: 2,3-dimethoxy-1,4-naphthoquinone
 related_synonym: 2,3-dimethoxy-1,4-naphthalenedione;   DMNQ;   Formula=C12H10O4;   InChI=1S/C12H10O4/c1-15-11-9(13)7-5-3-4-6-8(7)10(14)12(11)16-2/h3-6H,1-2H3;   InChIKey=ZEGDFCCYTFPECB-UHFFFAOYSA-N;   NSC 69355;   SMILES=COC1=C(OC)C(=O)c2ccccc2C1=O
 xref: CAS:6956-96-3
 xref_mesh: MESH:C063002
 xref: PMID:19338340;   PMID:20803752;   PMID:8103030;   PMID:8393647;   Patent:US4628062;   Patent:US5314914;   Reaxys:2049895

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Path 1
Term Annotations click to browse term
  CHEBI ontology 2
    role 2
      chemical role 1
        environmental contaminant 0
          naphthalene 0
            1,4-naphthoquinone 0
              2,3-dimethoxynaphthalene-1,4-dione 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 2
    subatomic particle 2
      composite particle 2
        hadron 2
          baryon 2
            nucleon 2
              atomic nucleus 2
                atom 2
                  main group element atom 2
                    p-block element atom 2
                      carbon group element atom 2
                        carbon atom 2
                          organic molecular entity 2
                            heteroorganic entity 2
                              organochalcogen compound 1
                                organooxygen compound 0
                                  carbonyl compound 0
                                    ketone 0
                                      cyclic ketone 0
                                        quinone 0
                                          naphthoquinone 0
                                            1,4-naphthoquinones 0
                                              1,4-naphthoquinone 0
                                                2,3-dimethoxynaphthalene-1,4-dione 0
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