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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hydrochlorothiazide
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Accession:CHEBI:5778 term browser browse the term
Definition:A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Synonyms:exact_synonym: 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
 related_synonym: Esidrix (TN);   Formula=C7H8ClN3O4S2;   InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13);   InChIKey=JZUFKLXOESDKRF-UHFFFAOYSA-N;   SMILES=NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl;   hidroclorotiazida;   hydrochlorothiazidum
 xref: CAS:58-93-5;   DrugBank:DB00999;   Drug_Central:1385;   HMDB:HMDB0001928;   KEGG:C07041;   KEGG:D00340;   LINCS:LSM-5308
 xref_mesh: MESH:D006852
 xref: PDBeChem:HCZ;   PMID:24055851;   PMID:24657333;   PMID:24849193;   Reaxys:625101;   Wikipedia:Hydrochlorothiazide


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Path 1
Term Annotations click to browse term
  CHEBI ontology 5177
    role 5144
      biological role 5144
        xenobiotic 168
          hydrochlorothiazide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5177
    subatomic particle 5168
      composite particle 5168
        hadron 5168
          baryon 5168
            nucleon 5168
              atomic nucleus 5168
                atom 5168
                  main group element atom 5140
                    p-block element atom 5137
                      chalcogen 5035
                        oxygen atom 5003
                          oxygen molecular entity 5003
                            hydroxides 4956
                              oxoacid 438
                                chalcogen oxoacid 80
                                  sulfur oxoacid 64
                                    sulfonic acid 34
                                      sulfonic acid derivative 34
                                        sulfonamide 11
                                          hydrochlorothiazide 0
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