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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Chromanol 293B
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Accession:CHEBI:34637 term browser browse the term
Definition:A 1-benzopyran that has formula C15H20N2O4S.
Synonyms:related_synonym: Formula=C15H20N2O4S;   InChI=1S/C15H20N2O4S/c1-5-22(19,20)17(4)13-11-8-10(9-16)6-7-12(11)21-15(2,3)14(13)18/h6-8,13-14,18H,5H2,1-4H3/t13-,14+/m0/s1;   InChIKey=HVSJHHXUORMCGK-UONOGXRCSA-N;   SMILES=CCS(=O)(=O)N(C)[C@@H]1[C@@H](O)C(C)(C)Oc2ccc(cc12)C#N
 xref: CAS:163163-23-3;   KEGG:C13820;   LINCS:LSM-20970
 xref_mesh: MESH:C103474


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Chromanol 293B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 multiple interactions ISO 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane inhibits the reaction [[KCNQ1 protein binds to KCNE3 protein] which affects the transport of Potassium] CTD PMID:11527966 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 decreases activity
multiple interactions		 ISO 6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane results in decreased activity of KCNQ1 protein
6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane results in decreased activity of [KCNQ1 protein binds to KCNE1 protein]
6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethylchromane inhibits the reaction [[KCNQ1 protein binds to KCNE3 protein] which affects the transport of Potassium]		 CTD PMID:11527966 PMID:16909339 PMID:20050851 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        nonmetal atom 19818
          oxygen atom 19558
            oxygen molecular entity 19558
              organooxygen compound 19206
                oxacycle 17918
                  benzopyran 11974
                    1-benzopyran 11728
                      Chromanol 293B 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    main group molecular entity 19835
                      p-block molecular entity 19835
                        carbon group molecular entity 19774
                          organic molecular entity 19771
                            organic molecule 19724
                              organic cyclic compound 19515
                                organic heterocyclic compound 18890
                                  organic heteropolycyclic compound 18310
                                    benzopyran 11974
                                      1-benzopyran 11728
                                        Chromanol 293B 3
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