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tandospirone citrate - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:tandospirone citrate
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Accession:CHEBI:32182 term browser browse the term
Definition:A citrate salt of tandospirone , comprising equimolar amounts of citric acid and tandospirone. It is an anxiolytic drug used in the treatment of anxiety disorders.
Synonyms:related_synonym: Formula=C21H29N5O2.C6H8O7;   InChI=1S/C21H29N5O2.C6H8O7/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21;7-3(8)1-6(13,5(11)12)2-4(9)10/h3,6-7,15-18H,1-2,4-5,8-14H2;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/t15-,16+,17+,18-;;   InChIKey=DMLGUJHNIWGCKM-DPFKZJTMSA-N;   SM 3997;   SM-3997 citrate;   SMILES=[C@]12([C@@]([C@@]3(C[C@]1(CC3)[H])[H])(C(N(C2=O)CCCCN4CCN(CC4)C5=NC=CC=N5)=O)[H])[H].C(=O)(O)C(CC(=O)O)(CC(=O)O)O;   Sediel;   metanopirone citrate
 xref: CAS:112457-95-1;   KEGG:D01992
 xref_mesh: MESH:C055267
 xref: PMID:11332196;   PMID:11481861;   PMID:11889759;   PMID:12355852;   PMID:12710093;   PMID:19638966;   PMID:2566565;   PMID:29254282;   PMID:31075722;   PMID:7904073

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tandospirone citrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]] CTD PMID:19352073 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        biochemical role 19566
          cofactor 16679
            ammonium 8311
              ammonium ion derivative 8306
                tandospirone(1+) 1
                  tandospirone citrate 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    main group molecular entity 19824
                      s-block molecular entity 19658
                        hydrogen molecular entity 19640
                          hydrides 19145
                            inorganic hydride 18162
                              pnictogen hydride 18152
                                nitrogen hydride 18059
                                  ammonium 8311
                                    ammonium ion derivative 8306
                                      tandospirone(1+) 1
                                        tandospirone citrate 1
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