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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ritlecitinib
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Accession:CHEBI:229233 term browser browse the term
Definition:A pyrrolopyrimidine that is 7H-pyrrolo[2,3-d]pyrimidine substituted at position 4 by a [(3R,6S)-6-methyl-1-(prop-2-enoyl)piperidin-3-yl]amino group. It is a dual inhibitor of Janus kinase 3 and the TEC family of tyrosine kinases.
Synonyms:exact_synonym: 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
 related_synonym: Formula=C15H19N5O;   InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1;   InChIKey=CBRJPFGIXUFMTM-WDEREUQCSA-N;   PF 06651600;   PF06651600;   SMILES=C[C@H]1CC[C@H](CN1C(=O)C=C)NC1=C2C=CNC2=NC=N1;   ritlecitinibum
 xref: CAS:1792180-81-4;   DrugBank:DB14924;   PMID:31082193;   PMID:32419304;   PMID:33757798;   PMID:34826225;   PMID:35000236;   PMID:35210753;   PMID:35732501;   PMID:36623678;   PMID:36807251;   PMID:36808638;   PMID:36872080;   PMID:36977960;   PMID:37062298;   PMID:37403610;   PMID:37455588;   PMID:37521227;   PMID:37550228;   PMID:37556041;   PMID:37561322;   PMID:37691236;   PMID:37707764;   PMID:37777018;   PMID:37812490;   PMID:37917289;   PMID:38051245;   PMID:38051803;   PMID:38141256;   Wikipedia:Ritlecitinib
 cyclic_relationship: is_conjugate_base_of CHEBI:229235


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19817
      application 19661
        anti-inflammatory agent 16598
          anti-inflammatory drug 14940
            ritlecitinib 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19789
                    p-block element atom 19789
                      carbon group element atom 19737
                        carbon atom 19733
                          organic molecular entity 19733
                            heteroorganic entity 19492
                              organochalcogen compound 19255
                                organooxygen compound 19172
                                  carbon oxoacid 18641
                                    carboxylic acid 18638
                                      carboacyl group 17698
                                        univalent carboacyl group 17698
                                          carbamoyl group 17548
                                            carboxamide 17548
                                              alpha,beta-unsaturated carboxylic acid amide 7106
                                                enamide 7106
                                                  acrylamides 6344
                                                    ritlecitinib 0
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