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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Desmethylazelastine
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Accession:CHEBI:197264 term browser browse the term
Synonyms:exact_synonym: 2-(azepan-4-yl)-4-[(4-chlorophenyl)methyl]phthalazin-1-one
 related_synonym: Formula=C21H22ClN3O;   InChI=1S/C21H22ClN3O/c22-16-9-7-15(8-10-16)14-20-18-5-1-2-6-19(18)21(26)25(24-20)17-4-3-12-23-13-11-17/h1-2,5-10,17,23H,3-4,11-14H2;   InChIKey=WRYCMIFVXDQIKN-UHFFFAOYSA-N;   SMILES=ClC1=CC=C(CC2=NN(C3CCCNCC3)C(=O)C=4C2=CC=CC4)C=C1
 xref: Chemspider:142721;   HMDB:HMDB0060534
 xref_mesh: MESH:C054114


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Desmethylazelastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity
multiple interactions		 ISO desmethylazelastine results in decreased activity of ABCB1 protein
desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; desmethylazelastine inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]		 CTD PMID:11231118 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19898
    chemical entity 19896
      atom 19896
        nonmetal atom 19818
          nitrogen atom 19000
            nitrogen molecular entity 19000
              organonitrogen compound 18853
                organonitrogen heterocyclic compound 18172
                  phthalazines 822
                    Desmethylazelastine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19898
    subatomic particle 19896
      composite particle 19896
        hadron 19896
          baryon 19896
            nucleon 19896
              atomic nucleus 19896
                atom 19896
                  main group element atom 19835
                    p-block element atom 19835
                      p-block molecular entity 19835
                        carbon group molecular entity 19774
                          organic molecular entity 19771
                            organic molecule 19724
                              organic cyclic compound 19515
                                organic heterocyclic compound 18890
                                  organic heteropolycyclic compound 18310
                                    organic heterobicyclic compound 17252
                                      phthalazines 822
                                        Desmethylazelastine 1
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