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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-goitrin
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Accession:CHEBI:183228 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5R)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (5R)-5-vinyl-1,3-oxazolidine-2-thione;   (R)-5-ethenyl-2-oxazolidinethione;   (R)-5-vinyl-2-oxazolidinethione;   BA 51-090278;   D-goitrin;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m1/s1;   InChIKey=UZQVYLOFLQICCT-SCSAIBSYSA-N;   SMILES=[H][C@]1(CNC(=S)O1)C=C;   epigoitrin
 xref: CAS:1072-93-1;   Chemspider:2297322;   PMID:11170613;   PMID:17401984;   PMID:19160787;   PMID:23901642;   PMID:25345127;   PMID:26989425;   PMID:27022502;   PMID:27468553;   PMID:28617329;   PMID:28894621;   PMID:30505662;   PMID:30792656;   PMID:31918015;   PMID:32805551;   PMID:33755912;   PMID:34627086;   PMID:7390339
 cyclic_relationship: is_enantiomer_of CHEBI:80751


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(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] CTD PMID:7532609 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
goitrin results in decreased expression of GSTP1 protein		 CTD PMID:7532609 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      biological role 19782
        antimicrobial agent 18141
          antiviral agent 11069
            (R)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            organic molecule 19655
                              organic cyclic compound 19468
                                organic heterocyclic compound 18848
                                  organic heteromonocyclic compound 17773
                                    oxazolidines 5442
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (R)-goitrin 2
                                          (RS)-goitrin 2
paths to the root