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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:(R)-goitrin
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Accession:CHEBI:183228 term browser browse the term
Definition:A 5-ethenyl-1,3-oxazolidine-2-thione that has R-configuration. It is a constituent of a traditional Chinese herbal medicine, Radix isatidis.
Synonyms:exact_synonym: (5R)-5-ethenyl-1,3-oxazolidine-2-thione
 related_synonym: (5R)-5-vinyl-1,3-oxazolidine-2-thione;   (R)-5-ethenyl-2-oxazolidinethione;   (R)-5-vinyl-2-oxazolidinethione;   BA 51-090278;   D-goitrin;   Formula=C5H7NOS;   InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8)/t4-/m1/s1;   InChIKey=UZQVYLOFLQICCT-SCSAIBSYSA-N;   SMILES=[H][C@]1(CNC(=S)O1)C=C;   epigoitrin
 xref: CAS:1072-93-1;   Chemspider:2297322;   PMID:11170613;   PMID:17401984;   PMID:19160787;   PMID:23901642;   PMID:25345127;   PMID:26989425;   PMID:27022502;   PMID:27468553;   PMID:28617329;   PMID:28894621;   PMID:30505662;   PMID:30792656;   PMID:31918015;   PMID:32805551;   PMID:33755912;   PMID:34627086;   PMID:7390339
 cyclic_relationship: is_enantiomer_of CHEBI:80751


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(RS)-goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 multiple interactions
increases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein] CTD PMID:7532609 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
increases expression
decreases expression		 EXP Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
goitrin results in decreased expression of GSTP1 protein		 CTD PMID:7532609 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        antimicrobial agent 18239
          antiviral agent 11339
            (R)-goitrin 2
              (RS)-goitrin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            organic molecule 19714
                              organic cyclic compound 19485
                                organic heterocyclic compound 18881
                                  organic heteromonocyclic compound 17787
                                    oxazolidines 5460
                                      5-ethenyl-1,3-oxazolidine-2-thione 2
                                        (R)-goitrin 2
                                          (RS)-goitrin 2
paths to the root