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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
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Accession:CHEBI:125562 term browser browse the term
Definition:A benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines.
Synonyms:related_synonym: 4-dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide;   D237;   Formula=C16H25N3O3;   InChI=1S/C16H25N3O3/c1-19(2)14-10-8-13(9-11-14)16(21)17-12-6-4-3-5-7-15(20)18-22/h8-11,22H,3-7,12H2,1-2H3,(H,17,21)(H,18,20);   InChIKey=MXWDSZWTBOCWBK-UHFFFAOYSA-N;   M-344;   M344;   N-hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide;   SMILES=CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO;   histone deacetylase inhibitor III
 xref: DrugBank:DB02565;   LINCS:LSM-37091;   PMID:10579829;   PMID:11831887;   PMID:16263156;   PMID:16724231;   PMID:16773328;   PMID:20526416;   PMID:20828393;   PMID:21854619;   PMID:22436652;   PMID:23638461;   PMID:28380503;   PMID:29073110;   Reaxys:8570090

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  CHEBI ontology 2
    role 2
      biological role 2
        biochemical role 2
          apoptosis inducer 0
            4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 0
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Term Annotations click to browse term
  CHEBI ontology 2
    subatomic particle 2
      composite particle 2
        hadron 2
          baryon 2
            nucleon 2
              atomic nucleus 2
                atom 2
                  main group element atom 2
                    p-block element atom 2
                      carbon group element atom 2
                        carbon atom 2
                          organic molecular entity 2
                            heteroorganic entity 2
                              organochalcogen compound 1
                                organooxygen compound 0
                                  carbon oxoacid 0
                                    carboxylic acid 0
                                      carboacyl group 0
                                        univalent carboacyl group 0
                                          carbamoyl group 0
                                            carboxamide 0
                                              monocarboxylic acid amide 0
                                                arenecarboxamide 0
                                                  benzamides 0
                                                    4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide 0
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