|
.306 |
.0 |
.132 |
.055 |
.002 |
.005 |
.073 |
.002 |
.0 |
.006 |
.032 |
.998 |
.001 |
.0 |
.004 |
.418 |
.651 |
.001 |
.001 |
.026 |
.154 |
.017 |
.0 |
.0 |
.237 |
.0 |
.003 |
.001 |
.0 |
.003 |
.074 |
.002 |
.0 |
.003 |
.004 |
.001 |
.068 |
.001 |
.035 |
.001 |
.0 |
-- |
.466 |
.0 |
.0 |
.001 |
.0 |
.017 |
.002 |
.001 |
.001 |
.062 |
.003 |
.0 |
.0 |
.005 |
.954 |
.998 |
.999 |
.824 |
.008 |
.014 |
.0 |
.033 |
.439 |
.003 |
.035 |
.037 |
.001 |
.005 |
.446 |
.002 |
.001 |
.024 |
.0 |
.023 |
.0 |
.006 |
.0 |
.006 |
.0 |
.005 |
.075 |
.005 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.0 |
.0 |
.01 |
.002 |
.001 |
.003 |
.306 |
-- |
-- |
-- |
.007 |
.03 |
.007 |
.0 |
.001 |
.002 |
.031 |
.004 |
.0 |
.0 |
.0 |
.002 |
.0 |
.014 |
.129 |
.0 |
.0 |
.005 |
.001 |
.007 |
.002 |
.144 |
.005 |
.164 |
.555 |
.01 |
.008 |
.233 |
.001 |
.024 |
.002 |
.112 |
.0 |
.001 |
-- |
-- |
-- |
.002 |
.001 |
.002 |
.014 |
.027 |
.0 |
.0 |
.006 |
.005 |
.262 |
.127 |
.012 |
.9 |
.013 |
.008 |
.0 |
.006 |
.002 |
.051 |
.012 |
.08 |
.919 |
.914 |
.242 |
.014 |
.21 |
.05 |
.001 |
.001 |
.01 |
.015 |
.002 |
.031 |
.663 |
.007 |
.0 |
.001 |
.0 |
.001 |
.0 |
.006 |
.0 |
.0 |
.0 |
.001 |
.0 |
.009 |
.001 |
.001 |
.0 |
.008 |
.006 |
.008 |
.005 |
.002 |
.003 |
.017 |
.0 |
.01 |
.009 |
.086 |
.107 |
.003 |
.031 |
.035 |
.22 |
.162 |
.0 |
.014 |
.001 |
.012 |
.0 |
.261 |
.21 |
.212 |
.013 |
.008 |
.991 |
.04 |
.002 |
.005 |
.005 |
.001 |
.545 |
.014 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.001 |
.014 |
.019 |
.002 |
.093 |
.333 |
.018 |
.012 |
.011 |
.013 |
.178 |
.002 |
.0 |
.001 |
.001 |
.002 |
.098 |
.0 |
.0 |
.004 |
.002 |
.0 |
.0 |
.002 |
.002 |
.008 |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
-- |
.048 |
.03 |
.042 |
.02 |
.025 |
.007 |
.003 |
.002 |
.24 |
.005 |
.005 |
.008 |
.013 |
.131 |
.006 |
.002 |
.003 |
.002 |
.001 |
.576 |
.173 |
.071 |
.015 |
.008 |
.003 |
.411 |
.142 |
.01 |
.013 |
.135 |
.091 |
.171 |
.002 |
.05 |
.164 |
.065 |
.044 |
.022 |
.023 |
.011 |
1.0 |
.547 |
.547 |
1.0 |
.978 |
.039 |
.002 |
.056 |
.014 |
.001 |
.005 |
.001 |
.001 |
.034 |
.001 |
.0 |
.002 |
.007 |
.011 |
.002 |
.002 |
.01 |
.009 |
.051 |
.0 |
.011 |
.047 |
.011 |
.003 |
-- |
-- |
-- |
.099 |
.003 |
.144 |
.003 |
.048 |
.002 |
.022 |
.006 |
.005 |
.004 |
.084 |
.004 |
.001 |
.005 |
.011 |
.037 |
.015 |
.006 |
.001 |
.055 |
.051 |
.189 |
.453 |
.08 |
.039 |
.003 |
.006 |
.017 |
.001 |
.727 |
.037 |
.043 |
.071 |
.186 |
.172 |
.002 |
.461 |
.019 |
.169 |
.009 |
.046 |
.026 |
.004 |
.012 |
.0 |
.114 |
.738 |
.813 |
.968 |
.007 |
.079 |
.116 |
.112 |
.0 |
.001 |
.001 |
.0 |
.0 |
.0 |
.001 |
.0 |
-- |
.004 |
.0 |
.0 |
.437 |
.002 |
.018 |
.001 |
.0 |
.0 |
.002 |
.149 |
.002 |
.028 |
.029 |
.012 |
.003 |
.47 |
.001 |
.005 |
.001 |
.007 |
.0 |
.0 |
.003 |
.009 |
.0 |
.0 |
.001 |
.0 |
.371 |
.383 |
1.0 |
.0 |
.001 |
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
--
|
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
Stxbp5
|
|
- |
- |
T |
C |
G |
T |
T |
G |
T |
C |
G |
C |
- |
T |
C |
C |
C |
G |
G |
C |
- |
A |
C |
T |
A |
C |
T |
A |
A |
G |
G |
A |
T |
A |
- |
C |
C |
C |
- |
T |
G |
2 |
G |
T |
C |
G |
A |
T |
A |
A |
A |
- |
T |
C |
C |
G |
A |
A |
3 |
A |
G |
T |
G |
T |
- |
T |
G |
C |
A |
A |
120 |
A |
C |
C |
G |
G |
G |
C |
A |
C |
A |
A |
A |
T |
G |
A |
T |
A |
T |
A |
C |
T |
C |
T |
C |
T |
C |
G |
C |
T |
C |
T |
T |
A |
2 |
- |
2 |
G |
T |
T |
C |
T |
- |
A |
C |
A |
G |
G |
G |
T |
T |
T |
C |
T |
G |
G |
C |
T |
G |
C |
C |
C |
T |
11 |
T |
G |
2 |
T |
A |
A |
A |
G |
- |
C |
G |
G |
T |
- |
C |
T |
C |
A |
A |
C |
G |
A |
A |
G |
T |
T |
C |
A |
C |
T |
T |
T |
G |
- |
T |
C |
T |
T |
T |
C |
A |
16 |
C |
T |
T |
T |
T |
T |
G |
T |
T |
G |
G |
A |
G |
A |
T |
G |
T |
G |
A |
- |
A |
- |
C |
C |
T |
- |
C |
A |
T |
2 |
C |
A |
C |
T |
T |
G |
T |
G |
T |
- |
G |
G |
T |
C |
A |
C |
G |
A |
A |
G |
C |
C |
T |
A |
C |
T |
A |
C |
G |
T |
T |
- |
G |
2 |
G |
T |
16 |
T |
T |
G |
C |
T |
C |
A |
2 |
- |
- |
C |
4 |
T |
G |
T |
C |
A |
T |
T |
A |
6 |
12 |
G |
- |
2 |
- |
C |
A |
C |
A |
- |
- |
13 |
C |
A |
C |
T |
G |
G |
C |
C |
C |
3 |
C |
T |
A |
C |
T |
G |
G |
C |
A |
G |
G |
T |
A |
A |
- |
G |
G |
A |
G |
T |
T |
C |
T |
C |
C |
T |
C |
T |
A |
A |
A |
G |
C |
T |
C |
C |
- |
2 |
G |
- |
- |
C |
A |
T |
C |
A |
T |
T |
C |
C |
T |
T |
A |
G |
2 |
50 |
48 |
T |
T |
G |
C |
A |
G |
C |
T |
A |
A |
7 |
C |
G |
T |
T |
G |
C |
A |
T |
G |
C |
G |
G |
G |
G |
- |
C |
G |
G |
G |
C |
A |
C |
T |
C |
T |
- |
T |
T |
A |
T |
A |
A |
C |
A |
C |
G |
C |
- |
T |
G |
T |
C |
G |
C |
T |
G |
T |
C |
G |
T |
G |
A |
A |
T |
A |
G |
C |
G |
G |
C |
T |
T |
T |
A |
C |
A |
A |
- |
48 |
A |
C |
G |
T |
G |
T |
T |
G |
G |
G |
- |
T |
- |
A |
A |
C |
C |
T |
A |
G |
G |
T |
T |
A |
3 |
- |
- |
A |
T |
A |
C |
C |
T |
T |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
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A
|
T
|
G
|
T
|
T
|
C
|
A
|
A
|
C
|
A
|
A
|
T
|
2
|
C
|
T
|
T
|
A
|
A
|
C
|
T
|
2
|
C
|
G
|
C
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C
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T
|
C
|
G
|
G
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A
|
A
|
T
|
C
|
G
|
A
|
T
|
T
|
T
|
G
|
C
|
A
|
-
|
C
|
C
|
G
|
T
|
G
|
G
|
C
|
T
|
G
|
2
|
G
|
T
|
A
|
A
|
G
|
G
|
-
|
G
|
A
|
C
|
A
|
C
|
2
|
C
|
T
|
T
|
G
|
C
|
120/-
|
T
|
T
|
T
|
A
|
A
|
C
|
T
|
G
|
T
|
C
|
G
|
G
|
-
|
A
|
C
|
C
|
C
|
G
|
C
|
A
|
T/G
|
C/G
|
T/C
|
C/T
|
T/C
|
-
|
T
|
T
|
C
|
T
|
C
|
A
|
G
|
-
|
42
|
-
|
T
|
C
|
C
|
T
|
G
|
T
|
G
|
A
|
G
|
A
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C
|
A
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C
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C
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C
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T
|
C
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A
|
A
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T
|
C
|
A
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T
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T
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T
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A
|
-
|
C
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T
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-
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-
|
C
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G
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C
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4
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-
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4
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C
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T
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G
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-
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T
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C
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C
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C
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C
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C
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T
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C
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A
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T
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G
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A
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A
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|
3
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2
|
T
|
A
|
C
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C
|
T
|
G
|
C
|
-
|
T
|
G
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T
|
A
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G
|
C
|
C
|
A
|
C
|
-/8
|
A
|
G/A
|
C
|
T
|
G
|
T
|
T
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|
C
|
A
|
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|
T
|
C
|
G
|
C/T
|
G/A
|
T/C
|
T/A
|
4
|
-
|
-
|
A
|
G
|
-
|
C
|
C
|
C
|
A
|
C
|
T
|
G
|
-
|
10
|
2
|
T
|
-
|
C
|
C
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C
|
-
|
G
|
C
|
C
|
T
|
-
|
-
|
A
|
A
|
-
|
A
|
G/T
|
C
|
-
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|
T
|
3
|
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|
-
|
A
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C
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A
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A
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-
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G
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|
C
|
A
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A
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T
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|
C
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A
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C
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G
|
3
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A
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G
|
T
|
C
|
C
|
T
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C
|
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T
|
C
|
T
|
C
|
G
|
G
|
C
|
A
|
T
|
C
|
A
|
T
|
4
|
-
|
A
|
-/2
|
-/2
|
T
|
C
|
C
|
T
|
G
|
A
|
C
|
T
|
T
|
C
|
A
|
G
|
A
|
2/-
|
-
|
-
|
C
|
C
|
A
|
T
|
G
|
C
|
G
|
A
|
G
|
G
|
-
|
T
|
A
|
C
|
-
|
A
|
A
|
-
|
C
|
A
|
G
|
C
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
A
|
G
|
T
|
T
|
C
|
T
|
C
|
4
|
C
|
G
|
C
|
C
|
-
|
G
|
G
|
G
|
T
|
A
|
T
|
A
|
G
|
A
|
A
|
G
|
C
|
T
|
C
|
-
|
G
|
G
|
A
|
G
|
A
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G
|
G
|
A
|
G
|
-
|
T
|
C
|
A
|
G
|
A
|
C
|
C
|
T
|
T
|
G
|
G
|
C
|
-
|
G
|
T
|
-
|
C
|
A
|
C
|
C
|
C
|
A
|
C
|
G
|
C
|
T
|
G
|
G
|
G
|
G
|
C
|
G
|
A
|
A
|
C
|
C
|
T
|
-
|
T
|
T
|
C
|
C
|
G
|
T
|
T
|
C
|
C
|
|