Cdc37 (cell division cycle 37, HSP90 cochaperone) - Rat Genome Database

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Gene: Cdc37 (cell division cycle 37, HSP90 cochaperone) Rattus norvegicus
Analyze
Symbol: Cdc37
Name: cell division cycle 37, HSP90 cochaperone
RGD ID: 71006
Description: Enables protein kinase binding activity; protein-folding chaperone binding activity; and transcription corepressor binding activity. Predicted to be involved in several processes, including positive regulation of type 2 mitophagy; protein folding; and protein stabilization. Predicted to act upstream of or within regulation of type I interferon-mediated signaling pathway and regulation of type II interferon-mediated signaling pathway. Located in ruffle membrane. Part of protein-containing complex. Orthologous to human CDC37 (cell division cycle 37, HSP90 cochaperone); PARTICIPATES IN protein kinase C (PKC) signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CDC37 (cell division cycle 37 S. cerevisiae homolog); cell division cycle 37; cell division cycle 37 homolog; cell division cycle 37 homolog (S. cerevisiae); hsp90 chaperone protein kinase-targeting subunit; hsp90 co-chaperone Cdc37; p50Cdc37
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,954,292 - 27,966,935 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl827,948,016 - 27,983,931 (-)EnsemblGRCr8
mRatBN7.2819,677,400 - 19,690,761 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,671,938 - 19,690,809 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx823,697,528 - 23,710,151 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,995,388 - 22,008,011 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,907,795 - 19,920,433 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,160,922 - 22,173,797 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,154,067 - 22,173,804 (-)Ensemblrn6Rnor6.0
Rnor_5.0822,217,096 - 22,229,971 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4820,164,150 - 20,176,763 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera821,072,564 - 21,085,065 (-)NCBICelera
RGSC_v3.1820,164,149 - 20,176,763 (-)NCBI
Cytogenetic Map8q13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
2-acetamidofluorene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
Abemaciclib  (ISO)
acetylsalicylic acid  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP,ISO)
dimethylarsinic acid  (EXP)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
FR900359  (ISO)
furfural  (ISO)
geldanamycin  (ISO)
hydralazine  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
Mesaconitine  (EXP)
methidathion  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (EXP)
niclosamide  (ISO)
nitrates  (ISO)
nitroglycerin  (EXP)
nobiletin  (ISO)
oxaliplatin  (ISO)
palbociclib  (ISO)
paracetamol  (ISO)
platycodin D  (ISO)
quercetin  (ISO)
Ribociclib  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex. Erazo T, etal., Mol Cell Biol. 2013 Apr;33(8):1671-86. doi: 10.1128/MCB.01246-12. Epub 2013 Feb 19.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Gene Data Set MGD Curation, June 12, 2002
5. CK2 binds, phosphorylates, and regulates its pivotal substrate Cdc37, an Hsp90-cochaperone. Miyata Y and Nishida E, Mol Cell Biochem. 2005 Jun;274(1-2):171-9.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Protein kinase C: poised to signal. Newton AC Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E395-402. Epub 2009 Nov 24.
8. Interaction of rat Cdc37-related protein with retinoblastoma gene product. Ozaki T and Sakiyama S, DNA Cell Biol. 1996 Nov;15(11):975-9.
9. Molecular cloning and cell cycle-dependent expression of a novel gene that is homologous to cdc37. Ozaki T, etal., DNA Cell Biol 1995 Dec;14(12):1017-23.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9660753   PMID:10409742   PMID:12489981   PMID:15082798   PMID:15489334   PMID:16280321   PMID:17189825   PMID:17349580   PMID:18566753   PMID:19091746   PMID:20458337   PMID:21855797  
PMID:25002582   PMID:26362850   PMID:29127155   PMID:29687307   PMID:30053369   PMID:36920636  


Genomics

Comparative Map Data
Cdc37
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,954,292 - 27,966,935 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl827,948,016 - 27,983,931 (-)EnsemblGRCr8
mRatBN7.2819,677,400 - 19,690,761 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,671,938 - 19,690,809 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx823,697,528 - 23,710,151 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,995,388 - 22,008,011 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,907,795 - 19,920,433 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0822,160,922 - 22,173,797 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl822,154,067 - 22,173,804 (-)Ensemblrn6Rnor6.0
Rnor_5.0822,217,096 - 22,229,971 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4820,164,150 - 20,176,763 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera821,072,564 - 21,085,065 (-)NCBICelera
RGSC_v3.1820,164,149 - 20,176,763 (-)NCBI
Cytogenetic Map8q13NCBI
CDC37
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,391,133 - 10,403,542 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,391,090 - 10,420,185 (-)Ensemblhg38GRCh38
GRCh371910,501,809 - 10,514,218 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,362,809 - 10,375,271 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341910,362,808 - 10,375,271NCBI
Celera1910,396,515 - 10,408,977 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef1910,081,863 - 10,094,337 (-)NCBIHuRef
CHM1_11910,502,536 - 10,515,003 (-)NCBICHM1_1
T2T-CHM13v2.01910,517,575 - 10,529,998 (-)NCBIT2T-CHM13v2.0
Cdc37
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39921,050,727 - 21,061,230 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl921,044,518 - 21,061,278 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38921,139,431 - 21,149,934 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl921,133,222 - 21,149,982 (-)Ensemblmm10GRCm38
MGSCv37920,942,985 - 20,954,350 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36920,888,943 - 20,900,308 (-)NCBIMGSCv36mm8
Celera918,407,255 - 18,418,620 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.72NCBI
Cdc37
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,641,236 - 1,651,288 (-)Ensembl
ChiLan1.0NW_0049554951,642,467 - 1,651,288 (-)NCBIChiLan1.0ChiLan1.0
CDC37
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,309,229 - 15,322,930 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,307,842 - 14,321,343 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,942,644 - 9,955,112 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,606,246 - 10,618,702 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,606,246 - 10,618,702 (-)EnsemblpanPan2panpan1.1
CDC37
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,727,702 - 50,738,197 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,727,749 - 50,736,269 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2050,598,319 - 50,608,815 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02051,249,729 - 51,260,450 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,249,761 - 51,260,446 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,456,068 - 50,466,564 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02050,885,097 - 50,895,593 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,125,770 - 51,136,267 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Cdc37
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,633,499 - 209,643,541 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659711,117 - 721,260 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936659711,165 - 721,207 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC37
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,201,579 - 69,225,994 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1269,202,695 - 69,212,909 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,534,504 - 69,544,718 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC37
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,427,220 - 9,439,469 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,427,191 - 9,439,913 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607410,563,853 - 10,576,327 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc37
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,521,272 - 2,535,475 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248282,523,761 - 2,533,387 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Cdc37
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1817,403,200 - 17,416,064 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Cdc37
124 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:64
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000042314
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000042314   ⟹   ENSRNOP00000051248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,954,294 - 27,983,740 (-)Ensembl
mRatBN7.2 Ensembl819,678,121 - 19,690,739 (-)Ensembl
Rnor_6.0 Ensembl822,160,922 - 22,173,797 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079949   ⟹   ENSRNOP00000072578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,948,016 - 27,967,403 (-)Ensembl
mRatBN7.2 Ensembl819,671,938 - 19,690,809 (-)Ensembl
Rnor_6.0 Ensembl822,154,067 - 22,173,804 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112085   ⟹   ENSRNOP00000076743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,954,294 - 27,967,015 (-)Ensembl
mRatBN7.2 Ensembl819,678,121 - 19,690,809 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000146994   ⟹   ENSRNOP00000107582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,954,294 - 27,983,931 (-)Ensembl
RefSeq Acc Id: NM_053743   ⟹   NP_446195
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,954,294 - 27,966,930 (-)NCBI
mRatBN7.2819,678,123 - 19,690,759 (-)NCBI
Rnor_6.0822,160,922 - 22,173,797 (-)NCBI
Rnor_5.0822,217,096 - 22,229,971 (-)NCBI
RGSC_v3.4820,164,150 - 20,176,763 (-)RGD
Celera821,072,564 - 21,085,065 (-)RGD
Sequence:
RefSeq Acc Id: XM_039080700   ⟹   XP_038936628
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,954,292 - 27,966,935 (-)NCBI
mRatBN7.2819,677,400 - 19,690,761 (-)NCBI
RefSeq Acc Id: NP_446195   ⟸   NM_053743
- UniProtKB: Q63692 (UniProtKB/Swiss-Prot),   Q8CH95 (UniProtKB/Swiss-Prot),   A0A140TAG9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072578   ⟸   ENSRNOT00000079949
Ensembl Acc Id: ENSRNOP00000051248   ⟸   ENSRNOT00000042314
RefSeq Acc Id: XP_038936628   ⟸   XM_039080700
- Peptide Label: isoform X1
- UniProtKB: A0A140TAG9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076743   ⟸   ENSRNOT00000112085
Ensembl Acc Id: ENSRNOP00000107582   ⟸   ENSRNOT00000146994
Protein Domains
Cdc37 C-terminal   Cdc37 Hsp90 binding   Cdc37 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63692-F1-model_v2 AlphaFold Q63692 1-379 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695776
Promoter ID:EPDNEW_R6300
Type:initiation region
Name:Cdc37_1
Description:cell division cycle 37
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0822,173,776 - 22,173,836EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71006 AgrOrtholog
BioCyc Gene G2FUF-31434 BioCyc
BioCyc Pathway PWY66-374 [C20 prostanoid biosynthesis] BioCyc
BioCyc Pathway Image PWY66-374 BioCyc
Ensembl Genes ENSRNOG00000033426 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000042314 ENTREZGENE
  ENSRNOT00000112085 ENTREZGENE
Gene3D-CATH 1.20.58.610 UniProtKB/Swiss-Prot
  6.10.140.250 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5598479 IMAGE-MGC_LOAD
InterPro Cdc37 UniProtKB/Swiss-Prot
  Cdc37_C UniProtKB/Swiss-Prot
  Cdc37_Hsp90-bd UniProtKB/Swiss-Prot
  Cdc37_Hsp90-bd_sf UniProtKB/Swiss-Prot
  Cdc37_N_dom UniProtKB/Swiss-Prot
KEGG Report rno:114562 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72349 IMAGE-MGC_LOAD
NCBI Gene 114562 ENTREZGENE
PANTHER HSP90 CO-CHAPERONE CDC37 UniProtKB/Swiss-Prot
  PTHR12800 UniProtKB/Swiss-Prot
Pfam CDC37_C UniProtKB/Swiss-Prot
  CDC37_M UniProtKB/Swiss-Prot
  CDC37_N UniProtKB/Swiss-Prot
PhenoGen Cdc37 PhenoGen
RatGTEx ENSRNOG00000033426 RatGTEx
SMART CDC37_C UniProtKB/Swiss-Prot
  CDC37_M UniProtKB/Swiss-Prot
  CDC37_N UniProtKB/Swiss-Prot
Superfamily-SCOP Hsp90 co-chaperone CDC37 UniProtKB/Swiss-Prot
UniProt A0A0G2K3C1_RAT UniProtKB/TrEMBL
  A0A140TAG9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y0C0_RAT UniProtKB/TrEMBL
  A0ABK0LVU3_RAT UniProtKB/TrEMBL
  A6JNP5_RAT UniProtKB/TrEMBL
  A6JNP6_RAT UniProtKB/TrEMBL
  A6JNP7_RAT UniProtKB/TrEMBL
  CDC37_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q8CH95 ENTREZGENE
UniProt Secondary Q8CH95 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-04-28 Cdc37  cell division cycle 37, HSP90 cochaperone  Cdc37  cell division cycle 37  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-23 Cdc37  cell division cycle 37  Cdc37  cell division cycle 37 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Cdc37  cell division cycle 37 homolog (S. cerevisiae)      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_homology has similarity to S. cerevisiae cdc37 70676