Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Senp2 | Rat | (-)-alpha-phellandrene | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of SENP2 mRNA | CTD | PMID:25075043 | Senp2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SENP2 mRNA | CTD | PMID:36331819 | Senp2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of SENP2 mRNA | CTD | PMID:22206623 | Senp2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of SENP2 mRNA | CTD | PMID:22206623 | Senp2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of SENP2 mRNA | CTD | PMID:27291303 | Senp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Senp2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SENP2 mRNA | CTD | PMID:21570461 | Senp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SENP2 mRNA | CTD | PMID:33387578 | Senp2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | SENP2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SENP2 mRNA | CTD | PMID:22574217 | Senp2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of SENP2 mRNA | CTD | PMID:21346803 | Senp2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SENP2 mRNA | CTD | PMID:30851411 | Senp2 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of SENP2 mRNA | CTD | PMID:19285098 | Senp2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in more ... | CTD | PMID:29535048 | Senp2 | Rat | 5-aza-2'-deoxycytidine | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Decitabine results in increased expression of SENP2 mRNA | CTD | PMID:27915011 | Senp2 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SENP2 mRNA | CTD | PMID:31881176 | Senp2 | Rat | acetylcholine | affects localization | ISO | Senp2 (Mus musculus) | 6480464 | SENP2 protein affects the localization of Acetylcholine | CTD | PMID:34509475 | Senp2 | Rat | aflatoxin B1 | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SENP2 mRNA | CTD | PMID:19770486 | Senp2 | Rat | all-trans-retinoic acid | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SENP2 mRNA | CTD | PMID:33167477 | Senp2 | Rat | alpha-phellandrene | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of SENP2 mRNA | CTD | PMID:25075043 | Senp2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SENP2 mRNA | CTD | PMID:16483693 | Senp2 | Rat | benzo[a]pyrene | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SENP2 mRNA | CTD | PMID:22316170 | Senp2 | Rat | benzo[a]pyrene | decreases methylation | ISO | SENP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SENP2 3' UTR | CTD | PMID:27901495 | Senp2 | Rat | benzo[a]pyrene | increases methylation | ISO | SENP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of SENP2 promoter | CTD | PMID:27901495 | Senp2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of SENP2 mRNA | CTD | PMID:19150397 | Senp2 | Rat | beta-lapachone | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of SENP2 mRNA | CTD | PMID:38218311 | Senp2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of SENP2 mRNA | CTD | PMID:34319233 | Senp2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SENP2 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 | Senp2 | Rat | bisphenol A | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SENP2 mRNA | CTD | PMID:29275510 | Senp2 | Rat | carbamazepine | affects expression | ISO | SENP2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SENP2 mRNA | CTD | PMID:25979313 | Senp2 | Rat | chlorpyrifos | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SENP2 mRNA | CTD | PMID:20350560 | Senp2 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of SENP2 mRNA | CTD | PMID:26577399 | Senp2 | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of SENP2 mRNA | CTD | PMID:23640034 | Senp2 | Rat | dexamethasone | multiple interactions | EXP | | 6480464 | [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] inhibits the reaction [TGFB1 protein results in more ... | CTD | PMID:29535048 | Senp2 | Rat | ethanol | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of SENP2 mRNA | CTD | PMID:30319688 | Senp2 | Rat | fenofibrate | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of SENP2 mRNA | CTD | PMID:21318169 | Senp2 | Rat | fenofibrate | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of SENP2 mRNA] | CTD | PMID:21318169 | Senp2 | Rat | fenthion | decreases expression | ISO | Senp2 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SENP2 mRNA | CTD | PMID:34813904 | Senp2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SENP2 mRNA | CTD | PMID:24136188 | Senp2 | Rat | folic acid | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of SENP2 mRNA | CTD | PMID:22206623 | Senp2 | Rat | formaldehyde | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SENP2 mRNA | CTD | PMID:23649840 | Senp2 | Rat | FR900359 | affects phosphorylation | ISO | SENP2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SENP2 protein | CTD | PMID:37730182 | Senp2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SENP2 mRNA | CTD | PMID:33387578 | Senp2 | Rat | glyphosate | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Glyphosate results in decreased expression of SENP2 mRNA | CTD | PMID:31295307 | Senp2 | Rat | methylmercury chloride | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SENP2 mRNA | CTD | PMID:28001369 | Senp2 | Rat | paracetamol | increases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SENP2 mRNA | CTD | PMID:22230336 | Senp2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SENP2 mRNA | CTD | PMID:33387578 | Senp2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SENP2 mRNA | CTD | PMID:36331819 | Senp2 | Rat | pirinixic acid | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SENP2 mRNA | CTD | PMID:21318169 | Senp2 | Rat | pirinixic acid | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in increased expression of SENP2 mRNA] | CTD | PMID:21318169 | Senp2 | Rat | rac-lactic acid | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SENP2 mRNA | CTD | PMID:30851411 | Senp2 | Rat | resveratrol | multiple interactions | ISO | SENP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SENP2 mRNA | CTD | PMID:23557933 | Senp2 | Rat | sodium arsenite | decreases expression | ISO | Senp2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of SENP2 mRNA | CTD | PMID:25270620 | Senp2 | Rat | sodium arsenite | increases expression | ISO | SENP2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SENP2 mRNA | CTD | PMID:38568856 | Senp2 | Rat | tetrachloromethane | decreases expression | ISO | Senp2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of SENP2 protein | CTD | PMID:29535048 | Senp2 | Rat | tetrachloromethane | increases expression | ISO | Senp2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SENP2 mRNA | CTD | PMID:31919559 | Senp2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SENP2 mRNA | CTD | PMID:34492290 | Senp2 | Rat | titanium dioxide | affects expression | ISO | Senp2 (Mus musculus) | 6480464 | titanium dioxide affects the expression of SENP2 mRNA | CTD | PMID:17656681 | Senp2 | Rat | titanium dioxide | decreases methylation | ISO | Senp2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SENP2 gene; titanium dioxide results in decreased methylation more ... | CTD | PMID:35295148 | Senp2 | Rat | Tributyltin oxide | increases expression | EXP | | 6480464 | bis(tri-n-butyltin)oxide results in increased expression of SENP2 mRNA | CTD | PMID:17553608 | Senp2 | Rat | trichostatin A | affects expression | ISO | SENP2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of SENP2 mRNA | CTD | PMID:28542535 | Senp2 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of SENP2 mRNA | CTD | PMID:30589522 | Senp2 | Rat | triphenyl phosphate | affects expression | ISO | SENP2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SENP2 mRNA | CTD | PMID:37042841 | Senp2 | Rat | trovafloxacin | multiple interactions | ISO | Senp2 (Mus musculus) | 6480464 | [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of SENP2 mRNA | CTD | PMID:18930950 | Senp2 | Rat | valproic acid | decreases expression | ISO | SENP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SENP2 mRNA | CTD | PMID:23179753 | Senp2 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of SENP2 mRNA | CTD | 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