Gpc2 (glypican 2) - Rat Genome Database

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Gene: Gpc2 (glypican 2) Rattus norvegicus
Analyze
Symbol: Gpc2
Name: glypican 2
RGD ID: 621363
Description: Involved in neuron differentiation; positive regulation of neuron projection development; and smoothened signaling pathway. Predicted to be located in endoplasmic reticulum. Predicted to be active in cell surface and synapse. Orthologous to human GPC2 (glypican 2); PARTICIPATES IN Hedgehog signaling pathway; glypican signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cerebroglycan; glypican 2 (cerebroglycan); glypican-2; HSPG M13
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,391,489 - 22,397,822 (-)NCBIGRCr8
mRatBN7.21217,277,875 - 17,284,297 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,277,875 - 17,284,208 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,244,924 - 18,251,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,868,646 - 18,874,972 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,922,063 - 17,928,389 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,593,041 - 19,599,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,593,041 - 19,599,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,649,636 - 21,655,969 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,858,354 - 17,864,687 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,847,875 - 17,854,209 (-)NCBI
Celera1219,202,336 - 19,208,665 (-)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
protein binding  (IPI,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Glypican-2 binds to midkine: the role of glypican-2 in neuronal cell adhesion and neurite outgrowth. Kurosawa N, etal., Glycoconj J. 2001 Jun;18(6):499-507.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. HB-GAM (pleiotrophin) reverses inhibition of neural regeneration by the CNS extracellular matrix. Paveliev M, etal., Sci Rep. 2016 Sep 27;6:33916. doi: 10.1038/srep33916.
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Cerebroglycan: an integral membrane heparan sulfate proteoglycan that is unique to the developing nervous system and expressed specifically during neuronal differentiation. Stipp CS, etal., J Cell Biol 1994 Jan;124(1-2):149-60.
11. Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response. Williams EH, etal., Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5869-74. Epub 2010 Mar 15.

Genomics

Comparative Map Data
Gpc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,391,489 - 22,397,822 (-)NCBIGRCr8
mRatBN7.21217,277,875 - 17,284,297 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,277,875 - 17,284,208 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,244,924 - 18,251,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,868,646 - 18,874,972 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,922,063 - 17,928,389 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,593,041 - 19,599,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,593,041 - 19,599,374 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,649,636 - 21,655,969 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,858,354 - 17,864,687 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,847,875 - 17,854,209 (-)NCBI
Celera1219,202,336 - 19,208,665 (-)NCBICelera
Cytogenetic Map12q11NCBI
GPC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,169,606 - 100,177,381 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,169,606 - 100,177,381 (-)EnsemblGRCh38hg38GRCh38
GRCh37799,767,229 - 99,775,004 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,605,165 - 99,612,926 (-)NCBINCBI36Build 36hg18NCBI36
Build 34799,411,879 - 99,419,641NCBI
Celera794,502,575 - 94,510,340 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,402,023 - 94,409,735 (-)NCBIHuRef
CHM1_1799,697,303 - 99,705,068 (-)NCBICHM1_1
T2T-CHM13v2.07101,409,400 - 101,417,191 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,127,317 - 99,135,078 (-)NCBI
Gpc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,271,918 - 138,278,288 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,271,917 - 138,278,267 (-)EnsemblGRCm39 Ensembl
GRCm385138,273,657 - 138,280,026 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,273,655 - 138,280,005 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,714,888 - 138,721,165 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,503,448 - 138,509,725 (-)NCBIMGSCv36mm8
Celera5135,256,511 - 135,262,788 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map577.0NCBI
Gpc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573630,859 - 637,296 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573630,859 - 637,296 (+)NCBIChiLan1.0ChiLan1.0
GPC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,088,532 - 118,096,221 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,353,164 - 166,363,059 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,204,355 - 92,213,750 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,637,059 - 105,645,115 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,637,682 - 105,644,888 (-)Ensemblpanpan1.1panPan2
GPC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,354,181 - 9,361,361 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,354,535 - 9,361,375 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha611,057,530 - 11,065,347 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,287,230 - 9,295,035 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,288,223 - 9,295,049 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.169,139,687 - 9,147,491 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,118,759 - 9,126,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,299,810 - 9,307,638 (+)NCBIUU_Cfam_GSD_1.0
Gpc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,606,525 - 133,612,846 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543424,319 - 429,903 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543424,244 - 429,903 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,169,343 - 8,175,580 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,169,229 - 8,175,848 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,346,211 - 7,352,851 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GPC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,892,092 - 12,899,288 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,892,057 - 12,898,657 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,381,153 - 3,388,396 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,734,526 - 16,740,841 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,734,407 - 16,740,845 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gpc2
34 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:433
Count of miRNA genes:228
Interacting mature miRNAs:269
Transcripts:ENSRNOT00000001849
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61443Btemp2Thermal response to stress QTL 23.30.000094body temperature trait (VT:0005535)core body temperature (CMO:0001036)121502518320794014Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12852542328064601Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12123297788Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
1600391Edcs2Endometrial carcinoma susceptibility QTL23.50.01uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)12683319017870186Rat
10755457Coatc14Coat color QTL 140.01759coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)12122591684Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382528064557Rat
2312418Kidm41Kidney mass QTL 413.70.0001kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)12119611090Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1581516Cm56Cardiac mass QTL 564.20.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)12129333307Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121107382524234895Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121363552330827399Rat
7204484Bp358Blood pressure QTL 3580.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121300829619212979Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12136247923Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12844949028302290Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000001849   ⟹   ENSRNOP00000001849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1217,277,875 - 17,284,208 (-)Ensembl
Rnor_6.0 Ensembl1219,593,041 - 19,599,374 (-)Ensembl
RefSeq Acc Id: NM_138511   ⟹   NP_612520
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,391,489 - 22,397,822 (-)NCBI
mRatBN7.21217,277,875 - 17,284,208 (-)NCBI
Rnor_6.01219,593,041 - 19,599,374 (-)NCBI
Rnor_5.01221,649,636 - 21,655,969 (-)NCBI
RGSC_v3.41217,858,354 - 17,864,687 (-)RGD
Celera1219,202,336 - 19,208,665 (-)RGD
Sequence:
RefSeq Acc Id: XM_039089051   ⟹   XP_038944979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,392,246 - 22,397,796 (-)NCBI
mRatBN7.21217,278,637 - 17,284,297 (-)NCBI
RefSeq Acc Id: XM_039089052   ⟹   XP_038944980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,391,489 - 22,396,739 (-)NCBI
mRatBN7.21217,277,875 - 17,283,123 (-)NCBI
RefSeq Acc Id: XM_039089053   ⟹   XP_038944981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,391,489 - 22,396,741 (-)NCBI
mRatBN7.21217,277,875 - 17,283,116 (-)NCBI
RefSeq Acc Id: XM_039089054   ⟹   XP_038944982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81222,391,489 - 22,395,015 (-)NCBI
mRatBN7.21217,277,875 - 17,281,414 (-)NCBI
RefSeq Acc Id: NP_612520   ⟸   NM_138511
- Peptide Label: precursor
- UniProtKB: P51653 (UniProtKB/Swiss-Prot),   A6KSU6 (UniProtKB/TrEMBL),   A6KSU5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000001849   ⟸   ENSRNOT00000001849
RefSeq Acc Id: XP_038944980   ⟸   XM_039089052
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944981   ⟸   XM_039089053
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944982   ⟸   XM_039089054
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944979   ⟸   XM_039089051
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P51653-F1-model_v2 AlphaFold P51653 1-579 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621363 AgrOrtholog
BioCyc Gene G2FUF-19774 BioCyc
Ensembl Genes ENSRNOG00000001367 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055011823 UniProtKB/Swiss-Prot
  ENSRNOG00060023937 UniProtKB/Swiss-Prot
  ENSRNOG00065000073 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001849.5 UniProtKB/Swiss-Prot
  ENSRNOT00055020080 UniProtKB/Swiss-Prot
  ENSRNOT00060041475 UniProtKB/Swiss-Prot
  ENSRNOT00065000124 UniProtKB/Swiss-Prot
InterPro Glypican UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glypican_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171517 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171517 ENTREZGENE
PANTHER GLYPICAN UniProtKB/TrEMBL
  GLYPICAN-2 UniProtKB/TrEMBL
  PTHR10822 UniProtKB/Swiss-Prot
  PTHR10822:SF24 UniProtKB/Swiss-Prot
Pfam Glypican UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gpc2 PhenoGen
PROSITE GLYPICAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001367 RatGTEx
  ENSRNOG00055011823 RatGTEx
  ENSRNOG00060023937 RatGTEx
  ENSRNOG00065000073 RatGTEx
UniProt A6KSU5 ENTREZGENE, UniProtKB/TrEMBL
  A6KSU6 ENTREZGENE, UniProtKB/TrEMBL
  GPC2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-26 Gpc2  glypican 2  Gpc2  glypican 2 (cerebroglycan)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gpc2  glypican 2 (cerebroglycan)    cerebroglycan  Name updated 1299863 APPROVED
2002-08-07 Gpc2  cerebroglycan      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains has five potential heparan sulfite attachment sites  
gene_expression expressed only in nerve tissue 728608
gene_expression mRNA expressed in immature neurons, disappearing after completion of cell migration and axon outgrowth 728608
gene_product member of integral membrane heparan sulfate proteoglycans (HSPGs), characterized by glycosylphosphatidylinositol (GPI) linkage and conserved structural motifs 728608
gene_protein protein has predicted mass of 58.6 kDa 728608