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Gene: Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3) Rattus norvegicus

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Symbol:

Sh3gl3

Name:

SH3 domain containing GRB2 like 3, endophilin A3

RGD ID:

620578

Description:

Predicted to enable identical protein binding activity. Involved in negative regulation of clathrin-dependent endocytosis and positive regulation of neuron differentiation. Located in acrosomal vesicle; early endosome; and presynapse. Is active in glutamatergic synapse; postsynaptic density, intracellular component; and postsynaptic endosome. Orthologous to human SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

endophilin-3; endophilin-A3; SH3 domain protein 2 C1; SH3 domain protein 2C; SH3 domain-containing GRB2-like 3; SH3 domain-containing GRB2-like protein 3; SH3-domain GRB2-like 3; Sh3d2c1; SH3P13

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Sh3gl3 (SH3-domain GRB2-like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sh3gl3 (SH3 domain containing GRB2 like 3, endophilin A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sh3gl3 (SH3-domain GRB2-like 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sh3gl3b (SH3-domain GRB2-like 3b)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	sh3gl3b (SH3-domain GRB2-like 3b)	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	sh3gl3a (SH3-domain GRB2-like 3a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	EndoA	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-57	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	unc-57	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sh3gl3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	145,533,728 - 145,664,881 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	145,533,728 - 145,664,881 (+)	Ensembl				GRCr8
mRatBN7.2	1	136,124,500 - 136,255,669 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	136,124,499 - 136,255,584 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	144,040,009 - 144,171,713 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	151,209,246 - 151,340,967 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	144,123,239 - 144,253,823 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	144,069,641 - 144,200,402 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	144,069,638 - 144,200,397 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	138,398,336 - 138,529,056 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	128,174,057 - 128,303,475 (+)	NCBI		Celera
RGSC_v3.1	1	138,476,741 - 138,607,462 (+)	NCBI
Cytogenetic Map	1	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,6-dinitrotoluene (EXP)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (EXP)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aldehydo-D-glucose (ISO)

all-trans-retinoic acid (EXP)

amiodarone (EXP)

amitriptyline (EXP)

amitrole (EXP)

ammonium chloride (EXP)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

butanal (ISO)

Butylbenzyl phthalate (EXP)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

clofibrate (ISO)

clomipramine (EXP)

D-glucose (ISO)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (EXP,ISO)

diethyl phthalate (EXP)

diethylstilbestrol (ISO)

diisobutyl phthalate (EXP)

diisononyl phthalate (EXP)

dorsomorphin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

glucose (ISO)

glyphosate (EXP)

imipramine (EXP)

ketoconazole (EXP)

lead(0) (ISO)

methimazole (EXP)

methoxychlor (EXP)

N,N-diethyl-m-toluamide (EXP)

okadaic acid (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenobarbital (EXP)

SB 431542 (ISO)

sodium arsenate (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endocytosis (IBA,IEA)

membrane organization (IBA)

negative regulation of clathrin-dependent endocytosis (IMP)

positive regulation of neuron differentiation (IMP)

regulation of clathrin-dependent endocytosis (IMP)

regulation of endocytosis (IEA)

Cellular Component

acrosomal vesicle (IDA)

cytoplasm (IEA,ISO)

cytosol (IBA,TAS)

early endosome (IDA,IEA)

early endosome membrane (IEA)

glutamatergic synapse (IBA,IDA,IMP)

membrane (IBA,IEA)

postsynaptic density, intracellular component (IDA,IMP)

postsynaptic endosome (IDA,IMP)

presynapse (IBA,IDA)

Molecular Function

identical protein binding (IEA,ISO)

lipid binding (IEA)

protein binding (IPI,ISO)

protein-macromolecule adaptor activity (IBA)

Molecular Pathway Annotations Click to see Annotation Detail View

clathrin-dependent synaptic vesicle endocytosis (ISO)

endocytosis pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking.	Chowdhury S, etal., Neuron. 2006 Nov 9;52(3):445-59.
2.	Identification of endophilins 1 and 3 as selective binding partners for VGLUT1 and their co-localization in neocortical glutamatergic synapses: implications for vesicular glutamate transporter trafficking and excitatory vesicle formation.	De Gois S, etal., Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):679-93. doi: 10.1007/s10571-006-9054-8. Epub 2006 May 19.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	Identification and characterization of a synaptojanin 2 splice isoform predominantly expressed in nerve terminals.	Nemoto Y, etal., J Biol Chem 2001 Nov 2;276(44):41133-42.
8.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
9.	Characterization of rtSH3p13 gene encoding a development protein involved in vesicular traffic in spermiogenesis.	Qiao Y, etal., Cell Res. 2004 Jun;14(3):197-207. doi: 10.1038/sj.cr.7290220.
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain.	Ringstad N, etal., Proc Natl Acad Sci U S A 1997 Aug 5;94(16):8569-74.
14.	Synaptic vesicle endocytosis.	Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
15.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16.	Inhibitory role of endophilin 3 in receptor-mediated endocytosis.	Sugiura H, etal., J Biol Chem. 2004 May 28;279(22):23343-8. doi: 10.1074/jbc.M312607200. Epub 2004 Apr 5.
17.	Endophilin isoforms have distinct characteristics in interactions with N-type Ca2+ channels and dynamin I.	Tian Q, etal., Neurosci Bull. 2012 Oct;28(5):483-92. doi: 10.1007/s12264-012-1257-z. Epub 2012 Jul 13.
18.	Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recycling.	Voglmaier SM, etal., Neuron. 2006 Jul 6;51(1):71-84. doi: 10.1016/j.neuron.2006.05.027.

Additional References at PubMed

PMID:15978591	PMID:16115810	PMID:21900206	PMID:22099461	PMID:23376485	PMID:28235806

Genomics

Comparative Map Data

Sh3gl3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	145,533,728 - 145,664,881 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	1	145,533,728 - 145,664,881 (+)	Ensembl				GRCr8
mRatBN7.2	1	136,124,500 - 136,255,669 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	136,124,499 - 136,255,584 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	1	144,040,009 - 144,171,713 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	151,209,246 - 151,340,967 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	144,123,239 - 144,253,823 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	144,069,641 - 144,200,402 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	144,069,638 - 144,200,397 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	1	138,398,336 - 138,529,056 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	1	128,174,057 - 128,303,475 (+)	NCBI		Celera
RGSC_v3.1	1	138,476,741 - 138,607,462 (+)	NCBI
Cytogenetic Map	1	q31	NCBI

SH3GL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	83,447,341 - 83,633,820 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	83,447,228 - 83,618,743 (+)	Ensembl			hg38	GRCh38
GRCh37	15	84,116,093 - 84,287,495 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	81,907,287 - 82,078,495 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	15	81,907,286 - 82,078,495	NCBI
Celera	15	60,298,989 - 60,470,347 (-)	NCBI		Celera
Cytogenetic Map	15	q25.2	NCBI
HuRef	15	60,379,941 - 60,551,319 (+)	NCBI		HuRef
CHM1_1	15	83,857,704 - 84,029,128 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	81,315,250 - 81,486,674 (+)	NCBI		T2T-CHM13v2.0

Sh3gl3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	81,824,581 - 81,956,618 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	81,823,588 - 81,956,627 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	7	82,173,808 - 82,307,420 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	82,173,840 - 82,307,419 (+)	Ensembl			mm10	GRCm38
MGSCv37	7	89,408,638 - 89,455,929 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	7	82,136,564 - 82,183,595 (+)	NCBI		MGSCv36	mm8
Celera	7	79,583,452 - 79,715,386 (+)	NCBI		Celera
Cytogenetic Map	7	D3	NCBI
cM Map	7	47.15	NCBI

Sh3gl3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	13,150,021 - 13,297,878 (-)	Ensembl
ChiLan1.0	NW_004955416	13,151,288 - 13,297,878 (-)	NCBI	ChiLan1.0	ChiLan1.0

SH3GL3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	72,275,820 - 72,440,698 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	76,435,092 - 76,599,937 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	61,988,584 - 62,153,543 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	81,337,223 - 81,502,229 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	81,337,529 - 81,501,770 (+)	Ensembl			panPan2	panpan1.1

SH3GL3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	55,287,460 - 55,340,736 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	55,287,460 - 55,340,571 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	57,849,401 - 57,991,318 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	55,633,727 - 55,769,378 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	55,633,124 - 56,121,658 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	55,141,227 - 55,277,053 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	55,351,137 - 55,486,712 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	55,688,264 - 55,825,678 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sh3gl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	128,158,006 - 128,283,492 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936483	18,050,899 - 18,176,519 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936483	18,051,023 - 18,176,514 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SH3GL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	51,381,097 - 51,514,225 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	51,381,091 - 51,514,253 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	56,871,306 - 57,006,768 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SH3GL3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	29	2,009,833 - 2,177,843 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	29	2,009,776 - 2,177,747 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	44,935,678 - 45,104,239 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sh3gl3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624768	19,168,951 - 19,321,184 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624768	19,168,922 - 19,320,366 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sh3gl3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	2	117,979,851 - 118,104,337 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sh3gl3
646 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	43
Count of miRNA genes:	36
Interacting mature miRNAs:	43
Transcripts:	ENSRNOT00000026870
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	131179947	176179947	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	137611478	182611478	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	51940904	168768703	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	101228864	146228864	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	132760429	191848948	Rat
631684	Bp117	Blood pressure QTL 117	8.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	120082258	165082258	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	112521556	157521556	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	66009857	160501508	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	142582336	182383862	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	51511344	153680016	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	130419227	175419227	Rat
631570	Bp94	Blood pressure QTL 94		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132889797	152403053	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	132966869	252856240	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	139442053	223964440	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	127329268	206393015	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	99645382	182701046	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	99645382	221502378	Rat
61346	Rf2	Renal disease susceptibility QTL 2	3.7		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	1	142582180	153680016	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	109493780	193400781	Rat
2317833	Alcrsp19	Alcohol response QTL 19	12.4	0.001	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1300153	Bp171	Blood pressure QTL 171	3.37		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	124975316	152612788	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	103779152	223964440	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	141173126	169168317	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	98879955	208479939	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	140833106	185833106	Rat
1641897	Alcrsp1	Alcohol response QTL 1			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	1	110389869	155389869	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	116099376	191260518	Rat
2293142	Bp314	Blood pressure QTL 314			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	101594089	146594089	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	131243790	176243790	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	96717367	160111531	Rat
737974	Bp161	Blood pressure QTL 161		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	129182274	174182274	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	132760429	191848948	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	115183611	176289080	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	51941022	208479811	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	102780511	182384005	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	111949780	210707719	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	128019551	173019551	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34184556	172281316	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34565911	208798288	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	93903998	191260518	Rat
61399	Tcat1	Tongue tumor resistance QTL 1	3.3		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)	1	108680016	153680016	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	139442053	223964440	Rat
724567	Tcas6	Tongue tumor susceptibility QTL 6	6.85		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	1	102359314	153680016	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	143092939	188092939	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	111949780	210707719	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	178317588	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	112521556	157521556	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	140048073	185048073	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	111949780	160574007	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	135021436	180021436	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	191190115	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	132966869	206393015	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	132760429	152404087	Rat
631548	Bp88	Blood pressure QTL 88	5	0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	140915717	185915717	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	132760429	191848948	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	111949780	228180370	Rat

Markers in Region

D1Uwm3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	136,140,529 - 136,140,660 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	144,085,668 - 144,085,798	NCBI	Rnor6.0
Rnor_5.0	1	145,017,354 - 145,017,484	UniSTS	Rnor5.0
RGSC_v3.4	1	138,414,359 - 138,414,490	RGD	RGSC3.4
RGSC_v3.4	1	138,414,360 - 138,414,490	UniSTS	RGSC3.4
Celera	1	128,190,077 - 128,190,207	UniSTS
RGSC_v3.1	1	138,492,765 - 138,492,896	RGD
Cytogenetic Map	1	q31	UniSTS

AU046686

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	136,209,284 - 136,209,372 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	144,154,186 - 144,154,273	NCBI	Rnor6.0
Rnor_5.0	1	145,085,848 - 145,085,935	UniSTS	Rnor5.0
RGSC_v3.4	1	138,483,267 - 138,483,354	UniSTS	RGSC3.4
Celera	1	128,257,837 - 128,257,924	UniSTS
Cytogenetic Map	1	q31	UniSTS

Sh3d2c2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	136,255,309 - 136,255,643 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	144,200,043 - 144,200,376	NCBI	Rnor6.0
Rnor_5.0	1	145,131,602 - 145,131,935	UniSTS	Rnor5.0
RGSC_v3.4	1	138,529,069 - 138,529,402	UniSTS	RGSC3.4
Celera	1	128,303,488 - 128,303,821	UniSTS
Cytogenetic Map	1	q31	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	66	164	91	90	59	70	59	6	331	169	10	143	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001414376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_031238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229485	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006229486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017589779	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275378	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063275400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB008159	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF009604	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF227439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026870 ⟹ ENSRNOP00000026870

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	145,533,728 - 145,664,881 (+)	Ensembl
mRatBN7.2 Ensembl	1	136,124,499 - 136,255,296 (+)	Ensembl
Rnor_6.0 Ensembl	1	144,069,638 - 144,200,029 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000079989 ⟹ ENSRNOP00000072673

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	145,627,662 - 145,664,881 (+)	Ensembl
mRatBN7.2 Ensembl	1	136,218,446 - 136,255,584 (+)	Ensembl
Rnor_6.0 Ensembl	1	144,070,754 - 144,200,397 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096616 ⟹ ENSRNOP00000095576

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	145,534,748 - 145,664,877 (+)	Ensembl
mRatBN7.2 Ensembl	1	136,125,487 - 136,255,297 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109733 ⟹ ENSRNOP00000091889

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	145,534,716 - 145,664,881 (+)	Ensembl
mRatBN7.2 Ensembl	1	136,125,488 - 136,255,297 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119037 ⟹ ENSRNOP00000095776

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	1	145,535,123 - 145,664,875 (+)	Ensembl
mRatBN7.2 Ensembl	1	136,125,870 - 136,255,297 (+)	Ensembl

RefSeq Acc Id:

NM_001414376 ⟹ NP_001401305

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,534,755 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,125,527 - 136,255,669 (+)	NCBI

RefSeq Acc Id:

NM_031238 ⟹ NP_112517

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,533,728 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,124,500 - 136,255,669 (+)	NCBI
Rnor_6.0	1	144,069,641 - 144,200,030 (+)	NCBI
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI
RGSC_v3.4	1	138,398,336 - 138,529,056 (+)	RGD
Celera	1	128,174,057 - 128,303,475 (+)	RGD

Sequence:

show sequence

GCCAGGAGCTAATGGTTCTGGAGAAATGCTAGAGCCAAAGAGAAGCCCGGATACAGGTGTGAAC
TGCGAGCGTTGAGGACAACAGTAGTGTTGATGACCCCTGACCCGACGTTGGGAAGCGTCCACAG
AATGCCATTCCTTTTAGGTAGAGACTGAAAGTTGGATGGTGTTTGTGTTGGTGTGAAGCATCGC
TGAAGTGGATTGAAGGCATTGGGAGCCACAGGGCCTTTGAAAGGTCAGATTCAGGGAAAGTAGA
CTTGTTGGTGGCACAAGAATTGATGCAAGGTCCGTTTCTGTGACTGGGTAGACATACTGTTCAG
TAGGAGCTCTAGACCCTGTGGAAAGGGTCCGGTGTACAGGACTCTCCCGAAGACCAGTCTGAAC
AATACTCTGCTGTTTAGTGAAAAAATAAGTGGTGCAGAAGGAACGAAGCTAGATGAAGAGTTTC
TGGATATGGAAAAGAAAATAGATATTACCAGTAAAGCTGTTGCAGAAATTCTTTCAAAAGCCAC
AGAGTATCTCCAGCCCAATCCAGCATACAGAGCTAAGCTAGGAATGCTGAACACTATGTCGAAG
CTCCGAGGGCAGGTGAAGGCCACCGGCTACCCACAGACCGAAGGCTTGCTGGGGGACTGCATGC
TCAAGTACGGCAGGGAGCTTGGAGAAGACTCTGCTTTTGGCAACTCATTGGTAGAAGTTGGTGA
GGCCCTGAAACTCATGGCTGAGGTGAAGGACTCTCTGGATATTAATGTGAAGCAGACTTTTATT
GACCCACTACAGCTACTGCAAGACAAAGATTTAAAAGAGATTGGGCACCACCTGAGAAAGCTAG
AAGGCCGCCGTCTGGACTATGATTATAAAAAGAAGCGGGTGGGTAAGATCCCCGAGGAAGAAAT
CAGACAAGCAGTAGAAAAGTTTGAAGAGTCAAAGGAGTTGGCCGAAAGAAGCATGTTTAATTTT
TTAGAAAATGACGTAGAGCAAGTGAGTCAGCTGGCCGTGTTTGTAGAGGCGGCGTTAGACTATC
ACAGGCAGTCCACCGAGATCCTGCAGGAGCTGCAGAACAAGCTAGAGCTGCGAATAGCTCTTGC
ATCCCAAGTCCCTAGGCGAGACTACATGCCAAAGCCTGTGAACACGAGTTCCACCAATGCCAAC
GGGGTCGAACCCAGCTCTTCGTCAAAGTTAACAGGTACTGACATTCCCTCGGACCAGCCCTGCT
GTCGTGGTCTCTATGACTTTGAGCCAGAAAACGAAGGAGAATTGGGATTTAAAGAAGGGGACAT
CATTACATTAACCAATCAGATAGATGAAAACTGGTATGAAGGAATGCTCCGTGGGGAATCCGGC
TTCTTCCCTATTAATTACGTGGAAGTCATTGTGCCTTTACCTCGGTAAATGTGTCTTTTGGACC
TGACTTCAGAACTGAAATGAATTGGCACCAGTGTTCAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006229481 ⟹ XP_006229543

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,535,027 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,125,886 - 136,255,533 (+)	NCBI
Rnor_6.0	1	144,070,883 - 144,200,125 (+)	NCBI
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI

Sequence:

show sequence

CTCCAAGGGGTTGCGGGCCATAGACTCGGGGTCTCCACAGTCCTCTTTCGGTCTGGGTTTCTGG
TCGCCTATGAAGGCGCGGGGGCGGGTAGCGGTCGCGCGCTCTGGGCTGCGCGTGTTGGTGCCTC
CTCCCCTGAGTCTCGGGTCTCCCGCTGCGCCCTGGCGGTTGTAAATCTGACCGGTTCGGCTGGC
AAGGGATCGGAGGTGGTGGGCTTGGGGGATGAGCTCCGAGAGGAGATCCTTCGGGACCAAGACC
GTGCTGTTTAGTGAAAAAATAAGTGGTGCAGAAGGAACGAAGCTAGATGAAGAGTTTCTGGATA
TGGAAAAGAAAATAGATATTACCAGTAAAGCTGTTGCAGAAATTCTTTCAAAAGCCACAGAGTA
TCTCCAGCCCAATCCAGCATACAGAGCTAAGCTAGGAATGCTGAACACTATGTCGAAGCTCCGA
GGGCAGGTGAAGGCCACCGGCTACCCACAGACCGAAGGCTTGCTGGGGGACTGCATGCTCAAGT
ACGGCAGGGAGCTTGGAGAAGACTCTGCTTTTGGCAACTCATTGGTAGAAGTTGGTGAGGCCCT
GAAACTCATGGCTGAGGTGAAGGACTCTCTGGATATTAATGTGAAGCAGACTTTTATTGACCCA
CTACAGCTACTGCAAGACAAAGATTTAAAAGAGATTGGGCACCACCTGAGAAAGCTAGAAGGCC
GCCGTCTGGACTATGATTATAAAAAGAAGCGGGTGGGTAAGATCCCCGAGGAAGAAATCAGACA
AGCAGTAGAAAAGTTTGAAGAGTCAAAGGAGTTGGCCGAAAGAAGCATGTTTAATTTTTTAGAA
AATGACGTAGAGCAAGTGAGTCAGCTGGCCGTGTTTGTAGAGGCGGCGTTAGACTATCACAGGC
AGTCCACCGAGATCCTGCAGGAGCTGCAGAACAAGCTAGAGCTGCGAATAGCTCTTGCATCCCA
AGTCCCTAGGCGAGACTACATGCCAAAGCCTGTGAACACGAGTTCCACCAATGCCAACGGGGTC
GAACCCAGCTCTTCGTCAAAGTTAACAGGTACTGACATTCCCTCGGACCAGCCCTGCTGTCGTG
GTCTCTATGACTTTGAGCCAGAAAACGAAGGAGAATTGGGATTTAAAGAAGGGGACATCATTAC
ATTAACCAATCAGATAGATGAAAACTGGTATGAAGGAATGCTCCGTGGGGAATCCGGCTTCTTC
CCTATTAATTACGTGGAAGTCATTGTGCCTTTACCTCGGTAAATGTGTCTTTTGGACCTGACTT
CAGAACTGAAATGAATTGGCACCAGTGTTCTCTCAGTGTGGTGTTCTGTGACATCCTCGCTCTC
TGGCCCACTTAATCACTTTTGTATGTGTGTTTTCTTTATAATGTATTTTGTATCAATTTAA

hide sequence

RefSeq Acc Id:

XM_006229483 ⟹ XP_006229545

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,600,211 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,191,059 - 136,255,533 (+)	NCBI
Rnor_6.0	1	144,136,096 - 144,200,125 (+)	NCBI
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI

Sequence:

show sequence

GAAGAGAGAATTGTCCACGGCCTATTACCTCAGGGAGGGAGTAGAGGGACTTTGCTTACTCCTA
TAGCTAAGTCAGTATTAATATTTTACATTTCCTGGTTTTCAGTATTCTCTCAGATCTATGTTAA
AAGAGCTACCATATGCCAAGGACTGGTTGATGTGCATTTTTGTATAAAATGAAGGCTCTTGGGC
CATGGAGTTGACTCAGCAGGTCAAGGTCCTCACTGCACAATTGTGACAACTCAGGTTCCATCCC
TGGAATTCACTGGAAGGATAGAACACTCTCAATTGTCATCCGACTTCTAGTGAACTGAGAATCC
CTTCCTAAAATAGGGCCACACCAGGCCTGAGGACAACCTCGATGGGTGTCTTAGCTGTTTAGTG
AAAAAATAAGTGGTGCAGAAGGAACGAAGCTAGATGAAGAGTTTCTGGATATGGAAAAGAAAAT
AGATATTACCAGTAAAGCTGTTGCAGAAATTCTTTCAAAAGCCACAGAGTATCTCCAGCCCAAT
CCAGCATACAGAGCTAAGCTAGGAATGCTGAACACTATGTCGAAGCTCCGAGGGCAGGTGAAGG
CCACCGGCTACCCACAGACCGAAGGCTTGCTGGGGGACTGCATGCTCAAGTACGGCAGGGAGCT
TGGAGAAGACTCTGCTTTTGGCAACTCATTGGTAGAAGTTGGTGAGGCCCTGAAACTCATGGCT
GAGGTGAAGGACTCTCTGGATATTAATGTGAAGCAGACTTTTATTGACCCACTACAGCTACTGC
AAGACAAAGATTTAAAAGAGATTGGGCACCACCTGAGAAAGCTAGAAGGCCGCCGTCTGGACTA
TGATTATAAAAAGAAGCGGGTGGGTAAGATCCCCGAGGAAGAAATCAGACAAGCAGTAGAAAAG
TTTGAAGAGTCAAAGGAGTTGGCCGAAAGAAGCATGTTTAATTTTTTAGAAAATGACGTAGAGC
AAGTGAGTCAGCTGGCCGTGTTTGTAGAGGCGGCGTTAGACTATCACAGGCAGTCCACCGAGAT
CCTGCAGGAGCTGCAGAACAAGCTAGAGCTGCGAATAGCTCTTGCATCCCAAGTCCCTAGGCGA
GACTACATGCCAAAGCCTGTGAACACGAGTTCCACCAATGCCAACGGGGTCGAACCCAGCTCTT
CGTCAAAGTTAACAGGTACTGACATTCCCTCGGACCAGCCCTGCTGTCGTGGTCTCTATGACTT
TGAGCCAGAAAACGAAGGAGAATTGGGATTTAAAGAAGGGGACATCATTACATTAACCAATCAG
ATAGATGAAAACTGGTATGAAGGAATGCTCCGTGGGGAATCCGGCTTCTTCCCTATTAATTACG
TGGAAGTCATTGTGCCTTTACCTCGGTAAATGTGTCTTTTGGACCTGACTTCAGAACTGAAATG
AATTGGCACCAGTGTTCTCTCAGTGTGGTGTTCTGTGACATCCTCGCTCTCTGGCCCACTTAAT
CACTTTTGTATGTGTGTTTTCTTTATAATGTATTTTGTATCAATTTAA

hide sequence

RefSeq Acc Id:

XM_006229485 ⟹ XP_006229547

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,625,932 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,209,718 - 136,255,669 (+)	NCBI
Rnor_6.0	1	144,161,621 - 144,200,402 (+)	NCBI
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI

Sequence:

show sequence

AAAATAGATATTACCAGTAAAGCTGTTGCAGAAATTCTTTCAAAAGCCACAGAGTATCTCCAGC
CCAATCCAGAGCTAAGCTAGGAATGCTGAACACTATGTCGAAGCTCCGAGGGCAGGTGAAGGCC
ACCGGCTACCCACAGACCGAAGGCTTGCTGGGGGACTGCATGCTCAAGTACGGCAGGGAGCTTG
GAGAAGACTCTGCTTTTGGCAACTCATTGGTAGAAGTTGGTGAGGCCCTGAAACTCATGGCTGA
GGTGAAGGACTCTCTGGATATTAATGTGAAGCAGACTTTTATTGACCCACTACAGCTACTGCAA
GACAAAGATTTAAAAGAGATTGGGCACCACCTGAGAAAGCTAGAAGGCCGCCGTCTGGACTATG
ATTATAAAAAGAAGCGGGTGGGTAAGATCCCCGAGGAAGAAATCAGACAAGCAGTAGAAAAGTT
TGAAGAGTCAAAGGAGTTGGCCGAAAGAAGCATGTTTAATTTTTTAGAAAATGACGTAGAGCAA
GTGAGTCAGCTGGCCGTGTTTGTAGAGGCGGCGTTAGACTATCACAGGCAGTCCACCGAGATCC
TGCAGGAGCTGCAGAACAAGCTAGAGCTGCGAATAGCTCTTGCATCCCAAGTCCCTAGGCGAGA
CTACATGCCAAAGCCTGTGAACACGAGTTCCACCAATGCCAACGGGGTCGAACCCAGCTCTTCG
TCAAAGTTAACAGGTACTGACATTCCCTCGGACCAGCCCTGCTGTCGTGGTCTCTATGACTTTG
AGCCAGAAAACGAAGGAGAATTGGGATTTAAAGAAGGGGACATCATTACATTAACCAATCAGAT
AGATGAAAACTGGTATGAAGGAATGCTCCGTGGGGAATCCGGCTTCTTCCCTATTAATTACGTG
GAAGTCATTGTGCCTTTACCTCGGTAAATGTGTCTTTTGGACCTGACTTCAGAACTGAAATGAA
TTGGCACCAGTGTTCTCTCAGTGTGGTGTTCTGTGACATCCTCGCTCTCTGGCCCACTTAATCA
CTTTTGTATGTGTGTTTTCTTTATAATGTATTTTGTATCAATTTAATTTGTATAACTGATTTCT
TTGTCCTAACTCATAAAAATAGTTTTCTTCTTGTTCTAAAAAGTCATTGCTTAAATGTATTTGC
TTCCTGTTGCTAAGAAAAGTAAATTGCGCCCATTCGAATGTCCTGGGTAGTCCTTAGCTGCAGT
GGGAACGCGCCCTTTGCGGCTATGAAAGCTAAAGATTTTGTTTCTTGACATTATTGACGGCATT
TGGTCTTTTCCTGTTTTAAGCTTACCTGTGAACAGCCCAATAAACATGGCACACTGTGTTCATA
AAA

hide sequence

RefSeq Acc Id:

XM_006229486 ⟹ XP_006229548

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,628,228 - 145,664,881 (+)	NCBI
mRatBN7.2	1	136,219,012 - 136,255,669 (+)	NCBI
Rnor_6.0	1	144,163,962 - 144,200,402 (+)	NCBI
Rnor_5.0	1	145,001,327 - 145,131,961 (+)	NCBI

Sequence:

show sequence

GAAGGCCACCGGCTACCCACAGACCGAAGGCTTGCTGGGGGACTGCATGCTCAAGTACGGCAGG
GAGCTTGGAGAAGACTCTGCTTTTGGAGAAGTGACACACGGAGGGTTGGACTGGCATCCTGGCC
AACCCTAATTTCCAGAGATGGTTTCCACTTCTAATTGGCAAGGACCCAGCTGTGAATTTACTTC
CTTTAAAAATGAGGCAACTCATTGGTAGAAGTTGGTGAGGCCCTGAAACTCATGGCTGAGGTGA
AGGACTCTCTGGATATTAATGTGAAGCAGACTTTTATTGACCCACTACAGCTACTGCAAGACAA
AGATTTAAAAGAGATTGGGCACCACCTGAGAAAGCTAGAAGGCCGCCGTCTGGACTATGATTAT
AAAAAGAAGCGGGTGGGTAAGATCCCCGAGGAAGAAATCAGACAAGCAGTAGAAAAGTTTGAAG
AGTCAAAGGAGTTGGCCGAAAGAAGCATGTTTAATTTTTTAGAAAATGACGTAGAGCAAGTGAG
TCAGCTGGCCGTGTTTGTAGAGGCGGCGTTAGACTATCACAGGCAGTCCACCGAGATCCTGCAG
GAGCTGCAGAACAAGCTAGAGCTGCGAATAGCTCTTGCATCCCAAGTCCCTAGGCGAGACTACA
TGCCAAAGCCTGTGAACACGAGTTCCACCAATGCCAACGGGGTCGAACCCAGCTCTTCGTCAAA
GTTAACAGGTACTGACATTCCCTCGGACCAGCCCTGCTGTCGTGGTCTCTATGACTTTGAGCCA
GAAAACGAAGGAGAATTGGGATTTAAAGAAGGGGACATCATTACATTAACCAATCAGATAGATG
AAAACTGGTATGAAGGAATGCTCCGTGGGGAATCCGGCTTCTTCCCTATTAATTACGTGGAAGT
CATTGTGCCTTTACCTCGGTAAATGTGTCTTTTGGACCTGACTTCAGAACTGAAATGAATTGGC
ACCAGTGTTCTCTCAGTGTGGTGTTCTGTGACATCCTCGCTCTCTGGCCCACTTAATCACTTTT
GTATGTGTGTTTTCTTTATAATGTATTTTGTATCAATTTAATTTGTATAACTGATTTCTTTGTC
CTAACTCATAAAAATAGTTTTCTTCTTGTTCTAAAAAGTCATTGCTTAAATGTATTTGCTTCCT
GTTGCTAAGAAAAGTAAATTGCGCCCATTCGAATGTCCTGGGTAGTCCTTAGCTGCAGTGGGAA
CGCGCCCTTTGCGGCTATGAAAGCTAAAGATTTTGTTTCTTGACATTATTGACGGCATTTGGTC
TTTTCCTGTTTTAAGCTTACCTGTGAACAGCCCAATAAACATGGCACACTGTGTTCATAAAA

hide sequence

RefSeq Acc Id:

XM_063275370 ⟹ XP_063131440

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,534,871 - 145,664,881 (+)	NCBI

RefSeq Acc Id:

XM_063275373 ⟹ XP_063131443

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,534,744 - 145,664,881 (+)	NCBI

RefSeq Acc Id:

XM_063275376 ⟹ XP_063131446

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,534,742 - 145,642,037 (+)	NCBI

RefSeq Acc Id:

XM_063275378 ⟹ XP_063131448

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,535,016 - 145,642,037 (+)	NCBI

RefSeq Acc Id:

XM_063275380 ⟹ XP_063131450

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,534,741 - 145,664,881 (+)	NCBI

RefSeq Acc Id:

XM_063275385 ⟹ XP_063131455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,535,012 - 145,664,881 (+)	NCBI

RefSeq Acc Id:

XM_063275400 ⟹ XP_063131470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	145,628,237 - 145,664,881 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001401305	(Get FASTA)	NCBI Sequence Viewer
	NP_112517	(Get FASTA)	NCBI Sequence Viewer
	XP_006229543	(Get FASTA)	NCBI Sequence Viewer
	XP_006229545	(Get FASTA)	NCBI Sequence Viewer
	XP_006229547	(Get FASTA)	NCBI Sequence Viewer
	XP_006229548	(Get FASTA)	NCBI Sequence Viewer
	XP_063131440	(Get FASTA)	NCBI Sequence Viewer
	XP_063131443	(Get FASTA)	NCBI Sequence Viewer
	XP_063131446	(Get FASTA)	NCBI Sequence Viewer
	XP_063131448	(Get FASTA)	NCBI Sequence Viewer
	XP_063131450	(Get FASTA)	NCBI Sequence Viewer
	XP_063131455	(Get FASTA)	NCBI Sequence Viewer
	XP_063131470	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC14884	(Get FASTA)	NCBI Sequence Viewer
	AAF36700	(Get FASTA)	NCBI Sequence Viewer
	AAH78800	(Get FASTA)	NCBI Sequence Viewer
	BAA22920	(Get FASTA)	NCBI Sequence Viewer
	EDM08719	(Get FASTA)	NCBI Sequence Viewer
	EDM08720	(Get FASTA)	NCBI Sequence Viewer
	EDM08721	(Get FASTA)	NCBI Sequence Viewer
	EDM08722	(Get FASTA)	NCBI Sequence Viewer
	EDM08723	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026870
	ENSRNOP00000072673
	ENSRNOP00000091889
	ENSRNOP00000095576
	ENSRNOP00000095576.1
	ENSRNOP00000095776
GenBank Protein	O35180	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_112517 ⟸ NM_031238
- Peptide Label:	isoform 2
- UniProtKB:	Q9JKT0 (UniProtKB/TrEMBL), F1M8F8 (UniProtKB/TrEMBL), A0A9K3Y7M5 (UniProtKB/TrEMBL), A0A8L2R634 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTMSKLRGQVKATGYPQTEGLLGDCMLK YGRELGEDSAFGNSLVEVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEG RRLDYDYKKKRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHR QSTEILQELQNKLELRIALASQVPRRDYMPKPVNTSSTNANGVEPSSSSKLTGTDIPSDQPCCR GLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPR hide sequence

RefSeq Acc Id:	XP_006229543 ⟸ XM_006229481
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6APE5 (UniProtKB/TrEMBL), A0A8L2R634 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSERRSFGTKTVLFSEKISGAEGTKLDEEFLDMEKKIDITSKAVAEILSKATEYLQPNPAYRA KLGMLNTMSKLRGQVKATGYPQTEGLLGDCMLKYGRELGEDSAFGNSLVEVGEALKLMAEVKDS LDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKKRVGKIPEEEIRQAVEKFEESK ELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQNKLELRIALASQVPRRDYMPK PVNTSSTNANGVEPSSSSKLTGTDIPSDQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENW YEGMLRGESGFFPINYVEVIVPLPR hide sequence

RefSeq Acc Id:	XP_006229545 ⟸ XM_006229483
- Peptide Label:	isoform X3
- UniProtKB:	Q9JKT0 (UniProtKB/TrEMBL), F1M8F8 (UniProtKB/TrEMBL), A0A9K3Y7M5 (UniProtKB/TrEMBL), A0A8L2R634 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEKKIDITSKAVAEILSKATEYLQPNPAYRAKLGMLNTMSKLRGQVKATGYPQTEGLLGDCMLK YGRELGEDSAFGNSLVEVGEALKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEG RRLDYDYKKKRVGKIPEEEIRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHR QSTEILQELQNKLELRIALASQVPRRDYMPKPVNTSSTNANGVEPSSSSKLTGTDIPSDQPCCR GLYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLRGESGFFPINYVEVIVPLPR hide sequence

RefSeq Acc Id:	XP_006229547 ⟸ XM_006229485
- Peptide Label:	isoform X5
- UniProtKB:	A0A8L2R634 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLNTMSKLRGQVKATGYPQTEGLLGDCMLKYGRELGEDSAFGNSLVEVGEALKLMAEVKDSLDI NVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKKRVGKIPEEEIRQAVEKFEESKELA ERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQNKLELRIALASQVPRRDYMPKPVN TSSTNANGVEPSSSSKLTGTDIPSDQPCCRGLYDFEPENEGELGFKEGDIITLTNQIDENWYEG MLRGESGFFPINYVEVIVPLPR hide sequence

RefSeq Acc Id:

XP_006229548 ⟸ XM_006229486

- Peptide Label:

isoform X10

- Sequence:

show sequence

MAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLRKLEGRRLDYDYKKKRVGKIPEEEIRQAV
EKFEESKELAERSMFNFLENDVEQVSQLAVFVEAALDYHRQSTEILQELQNKLELRIALASQVP
RRDYMPKPVNTSSTNANGVEPSSSSKLTGTDIPSDQPCCRGLYDFEPENEGELGFKEGDIITLT
NQIDENWYEGMLRGESGFFPINYVEVIVPLPR

hide sequence

Ensembl Acc Id:

ENSRNOP00000026870 ⟸ ENSRNOT00000026870

Ensembl Acc Id:

ENSRNOP00000072673 ⟸ ENSRNOT00000079989

Ensembl Acc Id:

ENSRNOP00000091889 ⟸ ENSRNOT00000109733

Ensembl Acc Id:

ENSRNOP00000095776 ⟸ ENSRNOT00000119037

Ensembl Acc Id:

ENSRNOP00000095576 ⟸ ENSRNOT00000096616

RefSeq Acc Id:	NP_001401305 ⟸ NM_001414376
- Peptide Label:	isoform 1
- UniProtKB:	O35180 (UniProtKB/Swiss-Prot), O35104 (UniProtKB/Swiss-Prot), A6JCJ2 (UniProtKB/TrEMBL), A6JCJ3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063131450 ⟸ XM_063275380
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063131446 ⟸ XM_063275376
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063131443 ⟸ XM_063275373
- Peptide Label:	isoform X4
- UniProtKB:	A6JCJ3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063131440 ⟸ XM_063275370
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AFE3 (UniProtKB/TrEMBL), A0A8L2R634 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063131455 ⟸ XM_063275385
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063131448 ⟸ XM_063275378
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063131470 ⟸ XM_063275400
- Peptide Label:	isoform X10

Protein Domains

BAR SH3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O35180-F1-model_v2	AlphaFold	O35180	1-347	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690182

Promoter ID:

EPDNEW_R685

Type:

multiple initiation site

Name:

Sh3gl3_1

Description:

SH3 domain containing GRB2 like 3, endophilin A3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	144,070,666 - 144,070,726	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620578	AgrOrtholog
BIND	134435
	134436
BioCyc Gene	G2FUF-58682	BioCyc
Ensembl Genes	ENSRNOG00000019776	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000026870	ENTREZGENE
	ENSRNOT00000079989	ENTREZGENE
	ENSRNOT00000096616	ENTREZGENE
	ENSRNOT00000096616.1	UniProtKB/Swiss-Prot
	ENSRNOT00000109733	ENTREZGENE
	ENSRNOT00000119037	ENTREZGENE
Gene3D-CATH	1.20.1270.60	UniProtKB/Swiss-Prot
	SH3 Domains	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7135194	IMAGE-MGC_LOAD
InterPro	AH/BAR_dom_sf	UniProtKB/Swiss-Prot
	BAR_dom	UniProtKB/Swiss-Prot
	Endophilin-A3_BAR	UniProtKB/Swiss-Prot
	Endophilin_A_SH3	UniProtKB/Swiss-Prot
	Endophilin_SH3RF	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93371	IMAGE-MGC_LOAD
NCBI Gene	81921	ENTREZGENE
PANTHER	PTHR14167:SF45	UniProtKB/Swiss-Prot
	SH3 DOMAIN-CONTAINING	UniProtKB/Swiss-Prot
Pfam	BAR	UniProtKB/Swiss-Prot
	SH3_1	UniProtKB/Swiss-Prot
PhenoGen	Sh3gl3	PhenoGen
PRINTS	SH3DOMAIN	UniProtKB/Swiss-Prot
PROSITE	BAR	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000019776	RatGTEx
SMART	BAR	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF103657	UniProtKB/Swiss-Prot
	SSF50044	UniProtKB/Swiss-Prot
UniProt	A0A8I6AFE3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6APE5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2R634	ENTREZGENE, UniProtKB/TrEMBL
	A0A9K3Y7M5	ENTREZGENE, UniProtKB/TrEMBL
	A6JCJ2	ENTREZGENE, UniProtKB/TrEMBL
	A6JCJ3	ENTREZGENE, UniProtKB/TrEMBL
	A6JCJ4_RAT	UniProtKB/TrEMBL
	A6JCJ5_RAT	UniProtKB/TrEMBL
	F1M8F8	ENTREZGENE
	O35104	ENTREZGENE
	O35180	ENTREZGENE
	Q9JKT0	ENTREZGENE, UniProtKB/TrEMBL
	SH3G3_RAT	UniProtKB/Swiss-Prot
UniProt Secondary	O35104	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-06-19	Sh3gl3	SH3 domain containing GRB2 like 3, endophilin A3	Sh3gl3	SH3 domain-containing GRB2-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-05-04	Sh3gl3	SH3 domain-containing GRB2-like 3	Sh3gl3	SH3-domain GRB2-like 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Sh3gl3	SH3-domain GRB2-like 3		SH3 domain protein 2 C1	Name updated	1299863	APPROVED
2004-09-10	Sh3gl3	SH3 domain protein 2 C1	Sh3d2c1		Symbol and Name updated	1299863	APPROVED
2002-08-07	Sh3d2c1	SH3 domain protein 2 C1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in brain and testis	633918

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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RGD Manual Annotations

Imported Annotations - KEGG (archival)