Sh3gl3 (SH3-domain GRB2-like 3) - Rat Genome Database

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Gene: Sh3gl3 (SH3-domain GRB2-like 3) Mus musculus
Analyze
Symbol: Sh3gl3
Name: SH3-domain GRB2-like 3
RGD ID: 1551861
MGI Page MGI
Description: Predicted to enable identical protein binding activity. Involved in synaptic vesicle uncoating. Located in cytoplasm. Is expressed in several structures, including adrenal gland; central nervous system; dorsal aorta; peripheral nervous system; and testis. Orthologous to human SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: EEN-B; EEN-B2; endophilin III; endophilin-3; endophilin-A3; MGC118269; SH3 domain protein 2 C2; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3; Sh3d2; Sh3d2c; Sh3d2c2; SH3P; SH3P13
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Sh3d2c-ps1  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,824,581 - 81,956,618 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,823,588 - 81,956,627 (+)EnsemblGRCm39 Ensembl
GRCm38782,173,808 - 82,307,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl782,173,840 - 82,307,419 (+)EnsemblGRCm38mm10GRCm38
MGSCv37789,408,638 - 89,455,929 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36782,136,564 - 82,183,595 (+)NCBIMGSCv36mm8
Celera779,583,452 - 79,715,386 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map747.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP,ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
calcitriol  (ISO)
clofibrate  (EXP)
clomipramine  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP,ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
dorsomorphin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
glyphosate  (ISO)
imipramine  (ISO)
ketoconazole  (ISO)
lead(0)  (ISO)
methimazole  (ISO)
methoxychlor  (ISO)
N,N-diethyl-m-toluamide  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Synaptic vesicle endocytosis. Saheki Y and De Camilli P, Cold Spring Harb Perspect Biol. 2012 Sep 1;4(9):a005645. doi: 10.1101/cshperspect.a005645.
Additional References at PubMed
PMID:8889548   PMID:9238627   PMID:9341169   PMID:9630982   PMID:9878254   PMID:10087302   PMID:10349636   PMID:10816441   PMID:11042159   PMID:11076861   PMID:11309660   PMID:11544199  
PMID:12034747   PMID:12456676   PMID:12477932   PMID:14610273   PMID:15978591   PMID:16141072   PMID:16141073   PMID:20064468   PMID:21873635   PMID:22099461   PMID:23187129   PMID:25471590  
PMID:25771685   PMID:27720640   PMID:29953872   PMID:32152276  


Genomics

Comparative Map Data
Sh3gl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39781,824,581 - 81,956,618 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl781,823,588 - 81,956,627 (+)EnsemblGRCm39 Ensembl
GRCm38782,173,808 - 82,307,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl782,173,840 - 82,307,419 (+)EnsemblGRCm38mm10GRCm38
MGSCv37789,408,638 - 89,455,929 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36782,136,564 - 82,183,595 (+)NCBIMGSCv36mm8
Celera779,583,452 - 79,715,386 (+)NCBICelera
Cytogenetic Map7D3NCBI
cM Map747.15NCBI
SH3GL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381583,447,341 - 83,633,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1583,447,228 - 83,618,743 (+)EnsemblGRCh38hg38GRCh38
GRCh371584,116,093 - 84,287,495 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361581,907,287 - 82,078,495 (+)NCBINCBI36Build 36hg18NCBI36
Build 341581,907,286 - 82,078,495NCBI
Celera1560,298,989 - 60,470,347 (-)NCBICelera
Cytogenetic Map15q25.2NCBI
HuRef1560,379,941 - 60,551,319 (+)NCBIHuRef
CHM1_11583,857,704 - 84,029,128 (+)NCBICHM1_1
T2T-CHM13v2.01581,315,250 - 81,486,674 (+)NCBIT2T-CHM13v2.0
Sh3gl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81145,533,728 - 145,664,881 (+)NCBIGRCr8
mRatBN7.21136,124,500 - 136,255,669 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1136,124,499 - 136,255,584 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1144,040,009 - 144,171,713 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01151,209,246 - 151,340,967 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01144,123,239 - 144,253,823 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01144,069,641 - 144,200,402 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1144,069,638 - 144,200,397 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01145,001,327 - 145,131,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41138,398,336 - 138,529,056 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11138,476,741 - 138,607,462 (+)NCBI
Celera1128,174,057 - 128,303,475 (+)NCBICelera
Cytogenetic Map1q31NCBI
Sh3gl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541613,150,021 - 13,297,878 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541613,151,288 - 13,297,878 (-)NCBIChiLan1.0ChiLan1.0
SH3GL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21672,275,820 - 72,440,698 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11576,435,092 - 76,599,937 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01561,988,584 - 62,153,543 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11581,337,223 - 81,502,229 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1581,337,529 - 81,501,770 (+)Ensemblpanpan1.1panPan2
SH3GL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1355,287,460 - 55,340,736 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl355,287,460 - 55,340,571 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha357,849,401 - 57,991,318 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0355,633,727 - 55,769,378 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl355,633,124 - 56,121,658 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1355,141,227 - 55,277,053 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0355,351,137 - 55,486,712 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0355,688,264 - 55,825,678 (+)NCBIUU_Cfam_GSD_1.0
Sh3gl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640128,158,006 - 128,283,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648318,050,899 - 18,176,519 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648318,051,023 - 18,176,514 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SH3GL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl751,381,097 - 51,514,225 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1751,381,091 - 51,514,253 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2756,871,306 - 57,006,768 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SH3GL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1292,009,833 - 2,177,843 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl292,009,776 - 2,177,747 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605944,935,678 - 45,104,239 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sh3gl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476819,168,951 - 19,321,184 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476819,168,922 - 19,320,366 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sh3gl3
4235 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1780
Count of miRNA genes:578
Interacting mature miRNAs:724
Transcripts:ENSMUST00000032874, ENSMUST00000177883, ENSMUST00000177895, ENSMUST00000178526, ENSMUST00000179150, ENSMUST00000179318, ENSMUST00000179800, ENSMUST00000180183, ENSMUST00000180243
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1300952Hcs1_mhepatocarcinogenesis susceptibility 1 (mouse)Not determined75732612191326352Mouse
1301465Egrm3_mearly growth rate (mouse)Not determined75732612191326352Mouse
1301663Skull9_mskull morphology 9 (mouse)Not determined75732612191326352Mouse
26884408Bzwq13_mbi-zygomatic width QTL 13, 16 week (mouse)761749748121399223Mouse
27095916Scvln15_msacral vertebrae length 2, 16 week (mouse)761749748123699223Mouse
25314305Vmm6_mvariable multisystem mineralization 6, eye (mouse)761849748102749207Mouse
1301383Aem2_manti-erythrocyte autoantibody modifier 2 (mouse)Not determined76413542498135653Mouse
26884381Bzwq2_mbi-zygomatic width QTL 2, 5 week (mouse)76524974896949207Mouse
26884440Sklq4_mskull length QTL 4, 5 week (mouse)765249748126499172Mouse
11553865Stmm1c_mskin tumor modifier of MSM 1c (mouse)76578898699788986Mouse
11553866Stmm1d_mskin tumor modifier of MSM 1d (mouse)76578898699788986Mouse
27095937Ulnl7_mulna length 7, 10 week (mouse)76644974898349207Mouse
12801463Rta1_mretinal aging 1 (mouse)76716802789089989Mouse
1301826Pgia3_mproteoglycan induced arthritis 3 (mouse)Not determined767290094101290240Mouse
1301784Ses2_msalmonella enteritidis susceptibility 2 (mouse)Not determined767290094101290240Mouse
1300620Pgia21_mproteoglycan induced arthritis 21 (mouse)Not determined767290094101290240Mouse
26884418Bzwq7_mbi-zygomatic width QTL 7, 10 week (mouse)767849748105449207Mouse
27226715Metcl3_mmetatarsal-calcaneal length 3, 5 week (mouse)767849748119499223Mouse
26884444Sklq8_mskull length QTL 8, 10 week (mouse)767849748124199223Mouse
26884451Sklq14_mskull length QTL 14, 16 week (mouse)767849748124999172Mouse
1300654Bomd1_mbone mineral density 1 (mouse)Not determined768365595102365702Mouse
27095907Scvln4_msacral vertebrae length 2, 5 week (mouse)769949748120499223Mouse
1301155Bpq7_mblood pressure QTL 7 (mouse)Not determined770143137104143379Mouse
10043973Obq29_mobesity QTL 29 (mouse)Not determined772263372106263372Mouse
4142319Powg_mpost-ovarectomy weight gain (mouse)Not determined7285710592582163Mouse
27095910Pglq13_mpelvic girdle length QTL 13, 16 week (mouse)773049748125699172Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773149748143153737Mouse
11553869Stmm2b_mskin tumor modifier of MSM 2a (mouse)773725965107725965Mouse
4142212Png1_mPostnatal growth 1 (mouse)Not determined7432612192394346Mouse
27226745Metcl9_mmetatarsal-calcaneal length 9, 10 week (mouse)774849748122199223Mouse
27226781Tibl3_mtibia length 3, 5 week (mouse)774849748122199223Mouse
1301566Adip3_madiposity 3 (mouse)Not determined775394215109394346Mouse
14746989Manh62_mmandible shape 62 (mouse)775742528109742528Mouse
26884398Humsd6_mhumerus midshaft diameter 6, 16 week (mouse)778649748136901729Mouse
10412110Cctq1_mcentral corneal thickness QTL 1 (mouse)Not determined780551681114551791Mouse
4142500Morq1_mmodifier of Rs1 QTL 1 (mouse)Not determined80551681114551791Mouse
27095930Ulnl10_mulna length 10, 16 week (mouse)780849748126699172Mouse
27095923Pglq3_mpelvic girdle length QTL 3, 5 week (mouse)781249748124199223Mouse
27095903Scvln10_msacral vertebrae length 2, 10 week (mouse)781449748126499172Mouse
27226765Tibl18_mtibia length 18, 16 week (mouse)781849748126499172Mouse

Markers in Region
U58887  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38782,307,272 - 82,307,392UniSTSGRCm38
MGSCv37789,455,782 - 89,455,902UniSTSGRCm37
Celera779,715,239 - 79,715,359UniSTS
Cytogenetic Map7D2-3UniSTS
Whitehead/MRC_RH7904.38UniSTS
Sh3d2c2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38782,307,060 - 82,307,393UniSTSGRCm38
MGSCv37789,455,570 - 89,455,903UniSTSGRCm37
Celera779,715,027 - 79,715,360UniSTS
Cytogenetic Map7D2-3UniSTS
cM Map741.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001277954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001417260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030242266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036152825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC139213 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC175489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC175660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK012114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK157464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE653420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE993218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM115813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CAAA01040903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  MG954304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000032874   ⟹   ENSMUSP00000032874
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,544 - 81,956,627 (+)Ensembl
GRCm38.p6 Ensembl782,174,796 - 82,307,419 (+)Ensembl
RefSeq Acc Id: ENSMUST00000177883   ⟹   ENSMUSP00000137207
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,604 - 81,956,627 (+)Ensembl
GRCm38.p6 Ensembl782,174,856 - 82,307,419 (+)Ensembl
RefSeq Acc Id: ENSMUST00000177895   ⟹   ENSMUSP00000137570
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,698 - 81,956,627 (+)Ensembl
GRCm38.p6 Ensembl782,174,950 - 82,307,419 (+)Ensembl
RefSeq Acc Id: ENSMUST00000178526   ⟹   ENSMUSP00000137482
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,920,094 - 81,956,436 (+)Ensembl
GRCm38.p6 Ensembl782,270,886 - 82,307,228 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179150
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,982 - 81,826,040 (+)Ensembl
GRCm38.p6 Ensembl782,175,234 - 82,176,292 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179318   ⟹   ENSMUSP00000137621
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,823,588 - 81,956,295 (+)Ensembl
GRCm38.p6 Ensembl782,173,840 - 82,307,087 (+)Ensembl
RefSeq Acc Id: ENSMUST00000179800
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,590 - 81,919,246 (+)Ensembl
GRCm38.p6 Ensembl782,174,842 - 82,270,038 (+)Ensembl
RefSeq Acc Id: ENSMUST00000180183
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,823,943 - 81,933,303 (+)Ensembl
GRCm38.p6 Ensembl782,174,195 - 82,284,095 (+)Ensembl
RefSeq Acc Id: ENSMUST00000180243
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl781,824,904 - 81,933,366 (+)Ensembl
GRCm38.p6 Ensembl782,175,156 - 82,284,158 (+)Ensembl
RefSeq Acc Id: NM_001277954   ⟹   NP_001264883
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
GRCm38782,174,796 - 82,307,420 (+)NCBI
Celera779,667,037 - 79,715,387 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001277955   ⟹   NP_001264884
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
GRCm38782,174,796 - 82,307,420 (+)NCBI
Celera779,667,037 - 79,715,387 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001417256   ⟹   NP_001404185
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,942 - 81,956,618 (+)NCBI
RefSeq Acc Id: NM_001417257   ⟹   NP_001404186
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
RefSeq Acc Id: NM_001417258   ⟹   NP_001404187
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
RefSeq Acc Id: NM_001417259   ⟹   NP_001404188
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
RefSeq Acc Id: NM_001417260   ⟹   NP_001404189
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
RefSeq Acc Id: NM_017400   ⟹   NP_059096
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,589 - 81,956,618 (+)NCBI
GRCm38782,174,796 - 82,307,420 (+)NCBI
MGSCv37789,408,638 - 89,455,929 (+)RGD
Celera779,667,037 - 79,715,387 (+)NCBI
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030242263   ⟹   XP_030098123
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,958 - 81,956,618 (+)NCBI
GRCm38782,175,210 - 82,307,410 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030242266   ⟹   XP_030098126
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,581 - 81,956,618 (+)NCBI
GRCm38782,174,822 - 82,307,410 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152823   ⟹   XP_036008716
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,983 - 81,956,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152824   ⟹   XP_036008717
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,824,581 - 81,956,618 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036152825   ⟹   XP_036008718
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39781,825,787 - 81,956,618 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_059096   ⟸   NM_017400
- Peptide Label: isoform 1
- UniProtKB: Q8R0B7 (UniProtKB/Swiss-Prot),   Q62421 (UniProtKB/Swiss-Prot),   A0A0R4J0B8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264883   ⟸   NM_001277954
- Peptide Label: isoform 2
- UniProtKB: Q497N4 (UniProtKB/TrEMBL),   J3QQ44 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001264884   ⟸   NM_001277955
- Peptide Label: isoform 3
- UniProtKB: Q9CZV7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030098126   ⟸   XM_030242266
- Peptide Label: isoform X4
- UniProtKB: Q497N4 (UniProtKB/TrEMBL),   J3QQ44 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030098123   ⟸   XM_030242263
- Peptide Label: isoform X2
- UniProtKB: Q8R0B7 (UniProtKB/Swiss-Prot),   Q62421 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSMUSP00000032874   ⟸   ENSMUST00000032874
RefSeq Acc Id: ENSMUSP00000137482   ⟸   ENSMUST00000178526
RefSeq Acc Id: ENSMUSP00000137570   ⟸   ENSMUST00000177895
RefSeq Acc Id: ENSMUSP00000137207   ⟸   ENSMUST00000177883
RefSeq Acc Id: ENSMUSP00000137621   ⟸   ENSMUST00000179318
RefSeq Acc Id: XP_036008717   ⟸   XM_036152824
- Peptide Label: isoform X4
- UniProtKB: Q497N4 (UniProtKB/TrEMBL),   J3QQ44 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008716   ⟸   XM_036152823
- Peptide Label: isoform X4
- UniProtKB: Q497N4 (UniProtKB/TrEMBL),   J3QQ44 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036008718   ⟸   XM_036152825
- Peptide Label: isoform X4
- UniProtKB: Q497N4 (UniProtKB/TrEMBL),   J3QQ44 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001404189   ⟸   NM_001417260
- Peptide Label: isoform 6
RefSeq Acc Id: NP_001404188   ⟸   NM_001417259
- Peptide Label: isoform 2
- UniProtKB: Q497N4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001404186   ⟸   NM_001417257
- Peptide Label: isoform 5
RefSeq Acc Id: NP_001404187   ⟸   NM_001417258
- Peptide Label: isoform 2
- UniProtKB: Q497N4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001404185   ⟸   NM_001417256
- Peptide Label: isoform 4
Protein Domains
BAR   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62421-F1-model_v2 AlphaFold Q62421 1-347 view protein structure

Promoters
RGD ID:8664647
Promoter ID:EPDNEW_M10355
Type:single initiation site
Name:Sh3gl3_1
Description:Mus musculus SH3-domain GRB2-like 3 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38782,269,718 - 82,269,778EPDNEW
RGD ID:6842011
Promoter ID:MM_KWN:51365
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:UC009ICY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36789,408,346 - 89,408,846 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:700011 AgrOrtholog
Ensembl Genes ENSMUSG00000030638 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032874 ENTREZGENE
  ENSMUST00000032874.14 UniProtKB/TrEMBL
  ENSMUST00000177883.8 UniProtKB/TrEMBL
  ENSMUST00000177895.8 UniProtKB/TrEMBL
  ENSMUST00000178526.2 UniProtKB/TrEMBL
  ENSMUST00000179318 ENTREZGENE
  ENSMUST00000179318.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1270.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AH/BAR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BAR_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin-A3_BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endophilin_A_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20408 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:700011 ENTREZGENE
NCBI Gene 20408 ENTREZGENE
PANTHER PTHR14167:SF45 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 DOMAIN-CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sh3gl3 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF103657 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J0B8 ENTREZGENE, UniProtKB/TrEMBL
  J3QK75_MOUSE UniProtKB/TrEMBL
  J3QQ08_MOUSE UniProtKB/TrEMBL
  J3QQ44 ENTREZGENE, UniProtKB/TrEMBL
  Q497N4 ENTREZGENE, UniProtKB/TrEMBL
  Q62421 ENTREZGENE
  Q8R0B7 ENTREZGENE
  Q9CZV7 ENTREZGENE, UniProtKB/TrEMBL
  SH3G3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8R0B7 UniProtKB/Swiss-Prot