Ptgdr (prostaglandin D2 receptor) - Rat Genome Database

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Gene: Ptgdr (prostaglandin D2 receptor) Rattus norvegicus
Analyze
Symbol: Ptgdr (Ensembl: Ptgdrl1)
Name: prostaglandin D2 receptor (Ensembl:prostaglandin D2 receptor-like 1)
RGD ID: 619707
Description: Enables prostaglandin D receptor activity. Involved in negative regulation of cytosolic calcium ion concentration; positive regulation of penile erection; and vasodilation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR (prostaglandin D2 receptor); PARTICIPATES IN eicosanoid signaling pathway; prostaglandin D2 signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC100365135; LOC100365135; PGD receptor-like; PGD2 receptor-like; prostaglandin D receptor; prostaglandin D receptor-like; prostaglandin D2 receptor-like; prostanoid DP receptor-like; Ptgdr2; Ptgdrl
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,790,499 - 19,797,873 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,790,499 - 19,797,873 (+)EnsemblGRCr8
mRatBN7.21517,360,304 - 17,367,679 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1517,360,304 - 17,367,679 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1519,534,419 - 19,541,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01520,492,893 - 20,500,200 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,747,817 - 18,755,124 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,195,606 - 19,196,508 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01523,162,010 - 23,162,912 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41519,345,555 - 19,352,929 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1517,315,866 - 17,323,221 (+)NCBICelera
RGSC_v3.11519,345,554 - 19,352,929 (+)NCBI
Cytogenetic Map15p14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)
plasma membrane  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Brain Prostaglandin D2 Increases Neurogenic Pressor Activity and Mean Arterial Pressure in Angiotensin II-Salt Hypertensive Rats. Asirvatham-Jeyaraj N, etal., Hypertension. 2019 Dec;74(6):1499-1506. doi: 10.1161/HYPERTENSIONAHA.119.13175. Epub 2019 Oct 7.
2. No association of PTGDR -441C/T polymorphism with asthma in a North Indian population. Birbian N, etal., Dis Markers. 2011;31(6):353-9. doi: 10.3233/DMA-2011-0850.
3. Pharmacological and functional characterization of novel EP and DP receptor agonists: DP1 receptor mediates penile erection in multiple species. Brugger N, etal., J Sex Med. 2008 Feb;5(2):344-56. Epub 2007 Nov 28.
4. Comparison of rat and dog models of vasodilatation and lipolysis for the calculation of a therapeutic index for GPR109A agonists. Carballo-Jane E, etal., J Pharmacol Toxicol Methods. 2007 Nov-Dec;56(3):308-16. Epub 2007 Jun 23.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Dominant expression of rat prostanoid DP receptor mRNA in leptomeninges, inner segments of photoreceptor cells, iris epithelium, and ciliary processes. Gerashchenko D, etal., J Neurochem 1998 Sep;71(3):937-45.
7. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
8. Loss of DP1 Aggravates Vascular Remodeling in Pulmonary Arterial Hypertension via mTORC1 Signaling. He Y, etal., Am J Respir Crit Care Med. 2020 May 15;201(10):1263-1276. doi: 10.1164/rccm.201911-2137OC.
9. PTGDR gene in asthma: a functional, genetic, and epigenetic study. Isidoro-García M, etal., Allergy. 2011 Dec;66(12):1553-62. doi: 10.1111/j.1398-9995.2011.02685.x. Epub 2011 Aug 24.
10. Polymorphisms of the PTGDR and LTC4S influence responsiveness to leukotriene receptor antagonists in Korean children with asthma. Kang MJ, etal., J Hum Genet. 2011 Apr;56(4):284-9. doi: 10.1038/jhg.2011.3. Epub 2011 Feb 10.
11. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
15. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
16. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. Qu WM, etal., Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17949-54. doi: 10.1073/pnas.0608581103. Epub 2006 Nov 8.
17. GOA pipeline RGD automated data pipeline
18. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
19. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
20. GIF-0173 protects against cerebral infarction through DP1 receptor activation. Thura M, etal., Exp Neurol. 2009 Oct;219(2):481-91. Epub 2009 Jul 2.
21. A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor. Wright DH, etal., Eur J Pharmacol 1999 Jul 14;377(1):101-15.
22. Association of PTGDR gene polymorphisms with asthma in two Caucasian populations. Zhu G, etal., Genes Immun. 2007 Jul;8(5):398-403. doi: 10.1038/sj.gene.6364399. Epub 2007 May 31.
Additional References at PubMed
PMID:11562489   PMID:12878180   PMID:12895603   PMID:15834430   PMID:16185683   PMID:18212515   PMID:20959461  


Genomics

Comparative Map Data
Ptgdr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81519,790,499 - 19,797,873 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1519,790,499 - 19,797,873 (+)EnsemblGRCr8
mRatBN7.21517,360,304 - 17,367,679 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1517,360,304 - 17,367,679 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1519,534,419 - 19,541,726 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01520,492,893 - 20,500,200 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01518,747,817 - 18,755,124 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,195,606 - 19,196,508 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01523,162,010 - 23,162,912 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41519,345,555 - 19,352,929 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1517,315,866 - 17,323,221 (+)NCBICelera
RGSC_v3.11519,345,554 - 19,352,929 (+)NCBI
Cytogenetic Map15p14NCBI
PTGDR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381452,267,698 - 52,280,914 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1452,267,698 - 52,276,724 (+)Ensemblhg38GRCh38
GRCh371452,734,416 - 52,743,442 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,804,181 - 51,813,192 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341451,804,180 - 51,813,191NCBI
Celera1432,602,359 - 32,611,369 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1432,895,105 - 32,904,115 (+)NCBIHuRef
CHM1_11452,673,595 - 52,682,607 (+)NCBICHM1_1
T2T-CHM13v2.01446,474,808 - 46,488,025 (+)NCBIT2T-CHM13v2.0
Ptgdr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391445,088,692 - 45,096,832 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1445,088,692 - 45,096,832 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381444,851,235 - 44,859,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1444,851,235 - 44,859,375 (-)Ensemblmm10GRCm38
MGSCv371445,470,910 - 45,479,050 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361443,773,112 - 43,781,252 (-)NCBIMGSCv36mm8
Celera1441,045,205 - 41,053,310 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1422.59NCBI
Ptgdr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540910,801,328 - 10,810,066 (-)Ensembl
ChiLan1.0NW_00495540910,801,370 - 10,810,161 (-)NCBIChiLan1.0ChiLan1.0
PTGDR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21553,398,345 - 53,410,180 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11452,614,856 - 52,626,691 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01432,863,852 - 32,873,492 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11451,149,155 - 51,158,158 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1451,149,155 - 51,158,161 (+)EnsemblpanPan2panpan1.1
PTGDR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1828,480,446 - 28,491,331 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl828,480,478 - 28,488,855 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha828,232,194 - 28,242,277 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0828,657,597 - 28,667,689 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl828,657,612 - 28,665,988 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1828,326,721 - 28,336,803 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0828,387,594 - 28,397,684 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0828,734,940 - 28,745,039 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ptgdr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864076,707,144 - 76,714,871 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366972,481,340 - 2,488,868 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366972,481,340 - 2,488,868 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGDR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1181,955,339 - 181,966,178 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11181,953,506 - 182,006,375 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21202,227,952 - 202,279,018 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGDR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12429,347,796 - 29,359,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2429,350,749 - 29,359,754 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605317,618,199 - 17,627,555 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptgdr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473116,777,678 - 16,785,130 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473116,776,050 - 16,785,178 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ptgdr
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11231,073,367 - 31,082,930 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ptgdr
36 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:126
Interacting mature miRNAs:138
Transcripts:ENSRNOT00000042545
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15132342855Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151691152132439851Rat

Markers in Region
D15Mit3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21517,362,897 - 17,363,086 (+)MAPPERmRatBN7.2
mRatBN7.21518,078,563 - 18,078,771 (+)MAPPERmRatBN7.2
Rnor_6.01518,093,208 - 18,093,415NCBIRnor6.0
Rnor_6.01519,198,200 - 19,198,388NCBIRnor6.0
Rnor_5.01522,070,681 - 22,070,888UniSTSRnor5.0
Rnor_5.01523,164,604 - 23,164,792UniSTSRnor5.0
RGSC_v3.41519,348,149 - 19,348,337UniSTSRGSC3.4
RGSC_v3.41520,063,838 - 20,064,045UniSTSRGSC3.4
RGSC_v3.41519,348,148 - 19,348,337RGDRGSC3.4
RGSC_v3.41520,063,837 - 20,064,045RGDRGSC3.4
Celera1517,318,461 - 17,318,649UniSTS
Celera1518,507,528 - 18,507,737UniSTS
RGSC_v3.11519,348,149 - 19,348,337RGD
RH 3.4 Map15143.08UniSTS
RH 3.4 Map15143.08RGD
SHRSP x BN Map1515.3399RGD
SHRSP x BN Map1515.3399UniSTS
Cytogenetic Map15p14UniSTS
D15Got105  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21517,362,888 - 17,362,989 (+)MAPPERmRatBN7.2
mRatBN7.21518,078,701 - 18,078,780 (-)MAPPERmRatBN7.2
Rnor_6.01519,198,191 - 19,198,291NCBIRnor6.0
Rnor_5.01523,164,595 - 23,164,695UniSTSRnor5.0
RGSC_v3.41519,348,140 - 19,348,240UniSTSRGSC3.4
RGSC_v3.41519,348,139 - 19,348,240RGDRGSC3.4
Celera1517,318,452 - 17,318,552UniSTS
RGSC_v3.11519,348,140 - 19,348,240RGD
RH 3.4 Map15144.42RGD
RH 3.4 Map15144.42UniSTS
Cytogenetic Map15p14UniSTS
BF391109  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21518,072,372 - 18,072,479 (+)MAPPERmRatBN7.2
Rnor_6.01518,087,297 - 18,087,403NCBIRnor6.0
Rnor_5.01522,064,770 - 22,064,876UniSTSRnor5.0
RGSC_v3.41520,057,647 - 20,057,753UniSTSRGSC3.4
Celera1518,501,337 - 18,501,443UniSTS
RH 3.4 Map15156.3UniSTS
Cytogenetic Map15p14UniSTS
PMC58788P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21518,080,715 - 18,080,828 (+)MAPPERmRatBN7.2
mRatBN7.21517,360,870 - 17,360,983 (-)MAPPERmRatBN7.2
mRatBN7.21518,080,715 - 18,080,828 (-)MAPPERmRatBN7.2
mRatBN7.21517,360,870 - 17,360,983 (+)MAPPERmRatBN7.2
Rnor_6.01519,196,173 - 19,196,285NCBIRnor6.0
Rnor_6.01518,095,360 - 18,095,472NCBIRnor6.0
Rnor_5.01523,162,577 - 23,162,689UniSTSRnor5.0
Rnor_5.01522,072,833 - 22,072,945UniSTSRnor5.0
RGSC_v3.41519,346,122 - 19,346,234UniSTSRGSC3.4
RGSC_v3.41520,065,990 - 20,066,102UniSTSRGSC3.4
Celera1517,316,433 - 17,316,545UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
1 16 6 28 17 1 5 10 21 5 5

Sequence


RefSeq Acc Id: NM_022241   ⟹   NP_071577
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81519,790,499 - 19,797,873 (+)NCBI
mRatBN7.21517,360,304 - 17,367,679 (+)NCBI
Rnor_6.01519,195,606 - 19,196,508 (+)NCBI
Rnor_5.01523,162,010 - 23,162,912 (+)NCBI
RGSC_v3.41519,345,555 - 19,352,929 (+)RGD
Celera1517,315,866 - 17,323,221 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_071577 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB71762 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000048101
GenBank Protein O35932 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_071577   ⟸   NM_022241
- UniProtKB: Q9R261 (UniProtKB/Swiss-Prot),   F1LS27 (UniProtKB/TrEMBL),   F1LLW6 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35932-F1-model_v2 AlphaFold O35932 1-357 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619707 AgrOrtholog
BioCyc Gene G2FUF-14265 BioCyc
Ensembl Genes ENSRNOG00000031535 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000042545 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Pglndn_D_rcpt UniProtKB/Swiss-Prot
  Prostanoid_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:63889 UniProtKB/Swiss-Prot
NCBI Gene 63889 ENTREZGENE
PANTHER PTHR11866 UniProtKB/Swiss-Prot
  PTHR11866:SF14 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PharmGKB PTGDR RGD
PhenoGen Ptgdr PhenoGen
PRINTS PROSTANOIDR UniProtKB/Swiss-Prot
  PRSTNOIDDPR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000031535 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt F1LLW6 ENTREZGENE, UniProtKB/TrEMBL
  F1LS27 ENTREZGENE
  O35932 ENTREZGENE, UniProtKB/Swiss-Prot
  Q9R261 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-04-17 Ptgdr  prostaglandin D2 receptor  LOC100365135  hypothetical protein LOC100365135  Data merged from RGD:2319639 737654 PROVISIONAL
2010-05-05 LOC100365135  hypothetical protein LOC100365135      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-02-25 Ptgdrli  prostaglandin D2 receptor   Ptgdrl  prostaglandin D receptor-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-25 Ptgdr  prostaglandin D2 receptor   Ptgdrli  prostaglandin D2 receptor   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-20 Ptgdrl  prostaglandin D receptor-like  Ptgdr  prostaglandin D receptor  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Ptgdr  prostaglandin D receptor  Ptgdr2  prostaglandin D2 receptor  Symbol and Name updated 1299863 APPROVED
2002-08-07 Ptgdr2  prostaglandin D2 receptor      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in eye and brain 633863