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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619707
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgdr
Name: prostaglandin D2 receptor
Acc ID: CHEBI:15551
Term: prostaglandin E2
Definition: Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins.
Chemical ID: MESH:D015232
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgdrmultiple interactionsISOPTGDR (Homo sapiens)6480464CTDDinoprostone binds to and results in increased activity of PTGDR protein; Dinoprostone inhibits the reaction [Prostaglandin D2 binds to PTGDR protein]PMID:27636113 PMID:9579725
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