F9 (coagulation factor IX) - Rat Genome Database

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Gene: F9 (coagulation factor IX) Rattus norvegicus
Analyze
Symbol: F9
Name: coagulation factor IX
RGD ID: 2589
Description: Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in blood coagulation and zymogen activation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in X-linked thrombophilia due to factor IX defect; X-linked warfarin sensitivity; and hemophilia B. Orthologous to human F9 (coagulation factor IX); PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acenocoumarol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: christmas factor; coagulation factor 9; Coagulation factor IX (plasma thromboplastic component Christmas disease hemophilia B); Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X143,388,642 - 143,433,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX143,388,621 - 143,433,146 (+)EnsemblGRCr8
mRatBN7.2X138,352,334 - 138,396,835 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX138,352,298 - 138,396,835 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX140,570,592 - 140,613,280 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X144,101,626 - 144,144,314 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X141,680,624 - 141,723,310 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X143,097,507 - 143,141,791 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX143,097,525 - 143,141,794 (+)Ensemblrn6Rnor6.0
Rnor_5.0X143,127,239 - 143,171,465 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X145,527,978 - 145,575,966 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX134,429,774 - 134,473,582 (+)NCBICelera
RGSC_v3.1X145,647,657 - 145,648,632 (+)NCBI
Cytogenetic MapXq36NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mutations in the catalytic domain of human coagulation factor IX: rapid characterization by direct genomic sequencing of DNA fragments displaying an altered melting behavior. Attree O, etal., Genomics. 1989 Apr;4(3):266-72.
2. A codon 338 nonsense mutation in the factor IX gene in unrelated hemophilia B patients: factor IX338 New York. Driscoll MC, etal., Blood. 1989 Aug 1;74(2):737-42.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Haemophilia B: database of point mutations and short additions and deletions--second edition. Giannelli F, etal., Nucleic Acids Res. 1991 Apr 25;19 Suppl:2193-219.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. The inhibitors of the tissue factor:factor VII pathway. Golino P Thromb Res. 2002 May 1;106(3):V257-65.
7. Haemostatic abnormalities persist despite glycaemic improvement by insulin therapy in lean type 2 diabetic patients. Knobl P, etal., Thromb Haemost. 1994 Jun;71(6):692-7.
8. Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. Laudes IJ, etal., Am J Pathol. 2002 May;160(5):1867-75.
9. A coagulation factor IX-deficient mouse model for human hemophilia B. Lin HF, etal., Blood. 1997 Nov 15;90(10):3962-6.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. Effect of dienogest on bleeding time, coagulation, fibrinolysis, and platelet aggregation in female rats. Nobukata H, etal., Toxicol Lett. 1999 Jan 11;104(1-2):93-101.
13. Blood coagulation. Norris LA, Best Pract Res Clin Obstet Gynaecol. 2003 Jun;17(3):369-83.
14. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
15. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
16. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
17. Disruption of a binding site for hepatocyte nuclear factor 4 results in hemophilia B Leyden. Reijnen MJ, etal., Proc Natl Acad Sci U S A 1992 Jul 15;89(14):6300-3.
18. GOA pipeline RGD automated data pipeline
19. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Comprehensive gene review and curation RGD comprehensive gene curation
22. Direct sequencing of the activation peptide and the catalytic domain of the factor IX gene in six species. Sarkar G, etal., Genomics 1990 Jan;6(1):133-43.
23. How it all starts: Initiation of the clotting cascade. Smith SA, etal., Crit Rev Biochem Mol Biol. 2015;50(4):326-36. doi: 10.3109/10409238.2015.1050550. Epub 2015 May 28.
24. Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice. Verma D, etal., Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7101-6. doi: 10.1073/pnas.0912181107. Epub 2010 Mar 29.
25. A factor IX-deficient mouse model for hemophilia B gene therapy. Wang L, etal., Proc Natl Acad Sci U S A 1997 Oct 14;94(21):11563-6.
26. [Human coagulation factor IX gene therapy in murine hemophilia B by hydrodynamic delivery and site-specific genomic integration.] Zhang L, etal., Zhonghua Xue Ye Xue Za Zhi. 2010 May;31(5):294-299.
Additional References at PubMed
PMID:2472424   PMID:2592373   PMID:8632006   PMID:9169594   PMID:14722079   PMID:15178576   PMID:20121197   PMID:20838739   PMID:23533145   PMID:25790442  


Genomics

Comparative Map Data
F9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X143,388,642 - 143,433,143 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX143,388,621 - 143,433,146 (+)EnsemblGRCr8
mRatBN7.2X138,352,334 - 138,396,835 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX138,352,298 - 138,396,835 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX140,570,592 - 140,613,280 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X144,101,626 - 144,144,314 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X141,680,624 - 141,723,310 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X143,097,507 - 143,141,791 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX143,097,525 - 143,141,794 (+)Ensemblrn6Rnor6.0
Rnor_5.0X143,127,239 - 143,171,465 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X145,527,978 - 145,575,966 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX134,429,774 - 134,473,582 (+)NCBICelera
RGSC_v3.1X145,647,657 - 145,648,632 (+)NCBI
Cytogenetic MapXq36NCBI
F9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X139,530,739 - 139,563,459 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX139,530,739 - 139,563,459 (+)Ensemblhg38GRCh38
GRCh37X138,612,898 - 138,645,618 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X138,440,561 - 138,473,283 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X138,338,414 - 138,371,137NCBI
CeleraX138,980,334 - 139,013,056 (+)NCBICelera
Cytogenetic MapXq27.1NCBI
HuRefX127,880,671 - 127,913,025 (+)NCBIHuRef
CHM1_1X138,523,783 - 138,556,510 (+)NCBICHM1_1
T2T-CHM13v2.0X137,842,731 - 137,875,455 (+)NCBIT2T-CHM13v2.0
F9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X59,044,675 - 59,076,120 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX59,044,824 - 59,076,119 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X59,999,329 - 60,030,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX59,999,464 - 60,030,759 (+)Ensemblmm10GRCm38
MGSCv37X57,252,641 - 57,283,935 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X56,346,248 - 56,377,542 (+)NCBIMGSCv36mm8
CeleraX46,438,864 - 46,469,954 (+)NCBICelera
Cytogenetic MapXA6NCBI
cM MapX33.5NCBI
F9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554895,749,187 - 5,780,866 (-)Ensembl
ChiLan1.0NW_0049554895,747,718 - 5,780,899 (-)NCBIChiLan1.0ChiLan1.0
F9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X138,978,746 - 139,013,001 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X138,982,348 - 139,016,603 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X128,684,709 - 128,719,020 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X138,934,144 - 138,967,180 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX138,934,167 - 138,967,087 (+)EnsemblpanPan2panpan1.1
F9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X109,501,341 - 109,533,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX109,501,341 - 109,533,798 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX95,328,677 - 95,361,130 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X111,487,863 - 111,520,319 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX111,487,863 - 111,520,319 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X108,621,887 - 108,654,350 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X110,806,410 - 110,838,864 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X110,485,875 - 110,518,335 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
F9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X107,524,352 - 107,562,278 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365138,053,615 - 8,090,234 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365138,052,998 - 8,090,245 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX114,218,707 - 114,250,429 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X114,218,704 - 114,250,436 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X130,417,620 - 130,448,319 (+)NCBISscrofa10.2Sscrofa10.2susScr3
F9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X114,618,397 - 114,650,827 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX114,618,639 - 114,651,365 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606552,325,926 - 52,357,748 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248087,136,703 - 7,175,709 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248087,137,482 - 7,175,255 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
F9
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X119,094,482 - 119,123,402 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in F9
69 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:370
Count of miRNA genes:238
Interacting mature miRNAs:285
Transcripts:ENSRNOT00000004559
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat

Markers in Region
DXWox30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X138,400,716 - 138,400,867 (+)MAPPERmRatBN7.2
Rnor_6.0X143,145,668 - 143,145,818NCBIRnor6.0
Rnor_5.0X143,175,347 - 143,175,497UniSTSRnor5.0
RGSC_v3.4X145,580,460 - 145,580,610UniSTSRGSC3.4
CeleraX134,477,464 - 134,477,614UniSTS
Cytogenetic MapXq36UniSTS
GDB:192503  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X138,395,201 - 138,395,422 (+)MAPPERmRatBN7.2
Rnor_6.0X143,140,153 - 143,140,373NCBIRnor6.0
Rnor_5.0X143,169,832 - 143,170,052UniSTSRnor5.0
RGSC_v3.4X145,574,945 - 145,575,165UniSTSRGSC3.4
CeleraX134,471,949 - 134,472,169UniSTS
Cytogenetic MapXq36UniSTS
RH127349  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X138,396,489 - 138,396,684 (+)MAPPERmRatBN7.2
Rnor_6.0X143,141,441 - 143,141,635NCBIRnor6.0
Rnor_5.0X143,171,120 - 143,171,314UniSTSRnor5.0
RGSC_v3.4X145,576,233 - 145,576,427UniSTSRGSC3.4
CeleraX134,473,237 - 134,473,431UniSTS
Cytogenetic MapXq36UniSTS
F9  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8X143,430,856 - 143,431,533 (+)Marker Load Pipeline
mRatBN7.2X138,394,548 - 138,395,225 (+)MAPPERmRatBN7.2
Rnor_6.0X143,139,500 - 143,140,176NCBIRnor6.0
Rnor_5.0X143,169,179 - 143,169,855UniSTSRnor5.0
RGSC_v3.4X145,574,292 - 145,574,968UniSTSRGSC3.4
CeleraX134,471,296 - 134,471,972UniSTS
Cytogenetic MapXq36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
5 10 14 47 86 84 59 20 59 4 150 52 30 26 42 25 3 3

Sequence


Ensembl Acc Id: ENSRNOT00000004559   ⟹   ENSRNOP00000004559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX143,388,621 - 143,433,143 (+)Ensembl
mRatBN7.2 EnsemblX138,352,298 - 138,396,835 (+)Ensembl
Rnor_6.0 EnsemblX143,097,525 - 143,141,794 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000124792   ⟹   ENSRNOP00000112029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX143,388,621 - 143,433,143 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000139261   ⟹   ENSRNOP00000110448
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX143,388,621 - 143,433,143 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155426   ⟹   ENSRNOP00000103255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX143,388,622 - 143,433,146 (+)Ensembl
RefSeq Acc Id: NM_031540   ⟹   NP_113728
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X143,388,642 - 143,433,143 (+)NCBI
mRatBN7.2X138,352,334 - 138,396,835 (+)NCBI
Rnor_6.0X143,097,560 - 143,141,786 (+)NCBI
Rnor_5.0X143,127,239 - 143,171,465 (+)NCBI
CeleraX134,429,774 - 134,473,582 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_113728 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41162 (Get FASTA)   NCBI Sequence Viewer  
  EDL86171 (Get FASTA)   NCBI Sequence Viewer  
  EDL86172 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004559
GenBank Protein P16296 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113728   ⟸   NM_031540
- Peptide Label: precursor
- UniProtKB: F1M1M6 (UniProtKB/Swiss-Prot),   P16296 (UniProtKB/Swiss-Prot),   A0A8L2Q0X9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004559   ⟸   ENSRNOT00000004559
Ensembl Acc Id: ENSRNOP00000103255   ⟸   ENSRNOT00000155426
Ensembl Acc Id: ENSRNOP00000110448   ⟸   ENSRNOT00000139261
Ensembl Acc Id: ENSRNOP00000112029   ⟸   ENSRNOT00000124792
Protein Domains
EGF-like   Gla   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16296-F1-model_v2 AlphaFold P16296 1-462 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702021
Promoter ID:EPDNEW_R12545
Type:initiation region
Name:F9_1
Description:coagulation factor IX
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X143,097,539 - 143,097,599EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2589 AgrOrtholog
BioCyc Gene G2FUF-880 BioCyc
Ensembl Genes ENSRNOG00000003430 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000004559 ENTREZGENE
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
  4.10.740.10 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro Coagulation_fac-like_Gla_dom UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  GLA-like_dom_SF UniProtKB/Swiss-Prot
  GLA_domain UniProtKB/Swiss-Prot
  Pept_S1A_FX UniProtKB/Swiss-Prot
  Peptidase_S1_coag_factors UniProtKB/Swiss-Prot
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
KEGG Report rno:24946 UniProtKB/Swiss-Prot
NCBI Gene 24946 ENTREZGENE
PANTHER COAGULATION FACTOR UniProtKB/Swiss-Prot
  PTHR24278:SF31 UniProtKB/Swiss-Prot
Pfam EGF UniProtKB/Swiss-Prot
  FXa_inhibition UniProtKB/Swiss-Prot
  Gla UniProtKB/Swiss-Prot
  Trypsin UniProtKB/Swiss-Prot
PharmGKB F9 RGD
PhenoGen F9 PhenoGen
PIRSF Factor_X UniProtKB/Swiss-Prot
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
  EGFBLOOD UniProtKB/Swiss-Prot
  GLABLOOD UniProtKB/Swiss-Prot
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  GLA_1 UniProtKB/Swiss-Prot
  GLA_2 UniProtKB/Swiss-Prot
  TRYPSIN_DOM UniProtKB/Swiss-Prot
  TRYPSIN_HIS UniProtKB/Swiss-Prot
  TRYPSIN_SER UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000003430 RatGTEx
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  GLA UniProtKB/Swiss-Prot
  Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF50494 UniProtKB/Swiss-Prot
  SSF57630 UniProtKB/Swiss-Prot
UniProt A0A8L2Q0X9 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LD11_RAT UniProtKB/TrEMBL
  A0ABK0LHW0_RAT UniProtKB/TrEMBL
  A0ABK0M2D0_RAT UniProtKB/TrEMBL
  A6K504_RAT UniProtKB/TrEMBL
  F1M1M6 ENTREZGENE
  FA9_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary F1M1M6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 F9  coagulation factor IX    coagulation factor 9   Name updated 1299863 APPROVED
2003-04-09 F9  coagulation factor 9     Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)  Name updated 629478 APPROVED
2002-06-10 F9  Coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)      Symbol and Name status set to approved 70586 APPROVED