WARFARIN PHARMACODYNAMICS PATHWAY (PW:0000731)

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Description

Warfarin, trade name Coumadin, is a widely used oral anticoagulant drug for the prevention of thrombosis and venous and arterial thromboembolism. It is a synthetic derivative of coumarin-derived dicoumarol. Warfarin is present as a racemic mixture of R and S enantiomers, both active, though not equally, and both metabolized via different routes. Warfarin is metabolized by several cytochrome P450 phase I biotransformation enzymes, depending on the enantiomeric form and producing a number of metab

Pathway Diagram:

Elsevier Inc. Vkorc1 warfarin warfarin ---| Thromboembolism warfarin ---| Thrombosis Vkorc1 ---- warfarin vitamin K cycle pathway warfarin ---| vitamin K cycle pathway warfarin ---| Vkorc1 coagulation cascade pathway warfarin ---| coagulation cascade pathway Thromboembolism Thrombosis
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warfarin pharmacodynamics pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:10402751
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:10402751
G F11 coagulation factor XI JBrowse link 16 50,179,458 50,201,644 RGD:10402751
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:10402751
G F13a1 coagulation factor XIII A1 chain JBrowse link 17 28,504,650 28,680,015 RGD:10402751
G F13b coagulation factor XIII B chain JBrowse link 13 56,598,891 56,623,132 RGD:10402751
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:10402751
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:10402751
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:10402751
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:10402751
G F8 coagulation factor VIII JBrowse link 18 367,862 399,242 RGD:10402751
G F9 coagulation factor IX JBrowse link X 143,097,507 143,141,791 RGD:10402751
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:10402751
G Fgb fibrinogen beta chain JBrowse link 2 182,028,044 182,035,026 RGD:10402751
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:10402751
G Ggcx gamma-glutamyl carboxylase JBrowse link 4 100,277,345 100,293,097 RGD:10402751
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:10402751
G Plat plasminogen activator, tissue type JBrowse link 16 74,098,263 74,122,897 RGD:10402751
G Plg plasminogen JBrowse link 1 48,521,828 48,563,895 RGD:10402751
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 JBrowse link 1 199,338,785 199,341,306 RGD:10402751
RGD:11354881

Pathway Gene Annotations

Disease Annotations Associated with Genes in the warfarin pharmacodynamics pathway
Disease TermsGene Symbols
Abortion, HabitualF5
Abortion, SpontaneousCol1a1 , F11 , F12 , F13a1 , F3
Acidosis, LacticPlat
Acquired AngioedemaF12 , F2 , F7
Acute Coronary SyndromeF12 , F2
Acute Kidney InjuryFga , Plat
Acute Lung InjuryF2 , F3 , Fga
Acute Traumatic CoagulopathyPlat
Adenomatous Polyposis ColiF5
AfibrinogenemiaFga , Fgb , Fgg
Aggressive PeriodontitisCol1a1
Airway ObstructionPlat
AlbuminuriaF7
Alzheimer DiseaseF2
Amphetamine-Related DisordersPlat
Amyloid Neuropathies, FamilialF10 , F2
Amyloidosis, FamilialFga
Amyloidosis, Familial VisceralFga
Anemia, Sickle CellF13a1 , F2 , F3
Aneurysm, DissectingCol1a1
Angina, StableF7
Angina, UnstableF7
AngioedemaF12 , Plat
Angioedemas, HereditaryF12 , F2 , F7
AnoxiaPlat
Anti-Neutrophil Cytoplasmic Antibody-Associated VasculitisF3
Antiphospholipid SyndromePlat
Aortic RuptureVkorc1
Aortic Valve InsufficiencyCol1a1
AphasiaPlat
AppendicitisF2
Arterial Occlusive DiseasesPlat
Arterial ThrombosisF7 , Plat
ArteriosclerosisF13a1 , F7
Arteriovenous FistulaCol1a1
Arthritis, ExperimentalF2 , Klkb1
Arthritis, RheumatoidF2
AsthmaF2 , F7 , Fga
AtherosclerosisF2 , Plat
Autism Spectrum DisorderKlkb1
Autoimmune DiseasesCol1a1 , F8
Back PainPlat
BacteremiaPlat
Behcet SyndromeF5
Beta-ThalassemiaCol1a1
Bile Duct DiseasesF3
Bisphosphonate-Associated Osteonecrosis of the JawCol1a1
Blood Coagulation DisordersF10 , F2 , F5 , Fga , Fgg , Ggcx , Plat , Vkorc1
Blood Coagulation Disorders, InheritedF7 , Ggcx
Bone Diseases, MetabolicCol1a1
Brain EdemaF2 , Plat
Brain InfarctionPlat
Brain InjuriesF2
Brain IschemiaF2 , F5 , Fga , Plat
Breast NeoplasmsF10 , F3 , F5 , F7
Budd-Chiari SyndromeF5
BurnsFga , Plat
CalcinosisCol1a1 , Vkorc1
Carcinoma, HepatocellularF2
Cardiac Allograft VasculopathyF3
Cardiac FibrosisCol1a1 , F3
Cardiac TamponadePlat
Cardiovascular DiseasesFgb
Carotid Artery DiseasesFgb
Carotid Artery InjuriesPlat
Carotid Artery ThrombosisF3 , Klkb1
Carotid StenosisF2
Celiac DiseaseF2
Central Nervous System Viral DiseasesPlat
Cerebral HemorrhageF13a1 , F2 , F7 , Plat
Cerebral InfarctionF2 , F5 , F7 , Plat
Cerebral Small Vessel DiseasesFga , Fgg
Chagas DiseaseF2
CholangitisCol1a1
CholestasisCol1a1 , Fga
Choroidal NeovascularizationF7
Chronic Allograft DysfunctionF7
Clear-Cell Metastatic Renal Cell CarcinomaF2
Coagulation Protein DisordersGgcx
Colonic NeoplasmsF5
Colorectal NeoplasmsF5 , F7
ConjunctivitisPlg
ContractureCol1a1
ContusionsF2
Coronary Artery DiseaseF2 , F7 , Fgb
Coronary DiseaseF12 , F13a1 , Vkorc1
Coronary ThrombosisPlat
Coumarin ResistanceF9 , Vkorc1
Coumarin SensitivityF9 , Vkorc1
Crohn DiseaseF13a1 , F2 , Fga
DeathF12
Dentinogenesis ImperfectaCol1a1
Dermatitis, Allergic ContactF13a1 , Plat
Dermatitis, AtopicF2
DermatofibrosarcomaCol1a1
Diabetes MellitusF3 , F7
Diabetes Mellitus, ExperimentalF2 , F3 , F7 , Fga
Diabetes Mellitus, Type 1F7 , Plat
Diabetes Mellitus, Type 2F12 , F2 , F3 , F7 , F8 , F9 , Fga , Fgb , Fgg , Plat
Diabetes, GestationalPlat
Diabetic AngiopathiesF3 , Plat
Diabetic FootPlat
Diabetic NephropathiesCol1a1 , F2 , F3 , Klkb1 , Plat
Diabetic NeuropathiesF7 , Plat
Diabetic RetinopathyF13a1 , F7
Disease Models, AnimalF7
Disseminated Intravascular CoagulationF13a1 , F2 , F3 , F7 , Fga , Plat
Drug-Induced Liver InjuryF13a1 , Fga , Plat , Plg
Drug-Related Side Effects and Adverse ReactionsFga , Vkorc1
DysarthriaF5
Dysfibrinogenemia, CongenitalFga , Fgb , Fgg
DyspneaF5
DysprothrombinemiaF2
EcchymosisCol1a1
Ehlers-Danlos SyndromeCol1a1
Ehlers-Danlos Syndrome Classic TypeCol1a1
Ehlers-Danlos Syndrome Type 1Col1a1
Ehlers-Danlos Syndrome Type 2Col1a1
Ehlers-Danlos Syndrome, Type VII, Autosomal DominantCol1a1
EmbolismPlat
Embolism and ThrombosisF3 , Plat
Embolism, CholesterolPlat
EndotoxemiaF12 , F2 , F3 , F5 , F7 , F8 , Fga , Plat
EnterocolitisKlkb1
Extrahepatic Portal Vein ObstructionF7
Eye DiseasesF2
Factor 8 Deficiency, AcquiredF8
Factor V DeficiencyF5
Factor VII DeficiencyF10 , F7
Factor X DeficiencyF10 , F7
Factor XI DeficiencyF11
Factor XII DeficiencyF12
Factor XIII DeficiencyF13a1 , F13b
Factor Xiii, A Subunit, Deficiency OfF13a1
Factor XIII, B Subunit, Deficiency OfF13b
Fatty LiverF2
Femoral FracturesCol1a1
Femur Head NecrosisF2 , F5 , Plat
Fetal DeathF5
FibrosisCol1a1
Fractures, BoneCol1a1
Glaucoma, Open-AngleCol1a1
GliomaF2
GlomerulonephritisF2 , Klkb1
Glomerulonephritis, MembranoproliferativeF5
Glomerulonephritis, MembranousPlg
Graft vs Host DiseaseF3
Hearing Loss, SensorineuralF2 , F5
Heart FailurePlat
Heart Valve DiseasesCol1a1
Hematoma, Epidural, SpinalPlat
Hematoma, SubduralPlat
Hematoma, Subdural, AcuteF7
HematuriaF7
Hemolytic-Uremic SyndromePlat
Hemophilia AF2 , F8 , F9 , Plat
Hemophilia BF2 , F9
HemorrhageF10 , F13a1 , F2 , F3 , F7 , F8 , Plat , Vkorc1
Hemorrhagic DisordersF7 , Ggcx
Hepatitis, AlcoholicCol1a1
Hepatitis, AutoimmuneF2
Hepatitis, ChronicPlat
Hepatitis, Viral, HumanCol1a1 , F2
Hereditary Angioedema Type IIIF12
Hernia, VentralCol1a1
High MyopiaCol1a1
Huntington DiseaseF2
HyperalgesiaF2
HyperbilirubinemiaF12 , F7
Hypereosinophilic SyndromeF5
HyperglycemiaF2 , F7
HyperhomocysteinemiaF10 , F12 , F2 , F8
HyperlipidemiasF3 , F7
Hyperostosis, Cortical, CongenitalCol1a1
HypertensionCol1a1 , F11 , F12 , F3 , F7 , Klkb1 , Plat , Plg
Hypertension, PulmonaryCol1a1 , F5
Hypertensive NephropathyCol1a1
HypertriglyceridemiaF7
HypertrophyF2
Hypertrophy, Left VentricularCol1a1
Hypertrophy, Right VentricularPlat
Hypodysfibrinogenemia, CongenitalFga , Fgg
HypoprothrombinemiasF2 , F7
HypotensionPlat
HypothyroidismF7
Hypoxia-Ischemia, BrainPlat
Idiopathic Pulmonary FibrosisF3
Infarction, Middle Cerebral ArteryF11 , F12 , Plat
InflammationF3 , Fgg
Inflammatory Bowel Disease 11Col1a1 , F2
Inflammatory Bowel DiseasesKlkb1
Insulin ResistanceF7
Intervertebral Disc DegenerationCol1a1
Intervertebral Disc DiseaseCol1a1
Intestinal Reperfusion InjuryF7
Intracranial Embolism and ThrombosisPlat
Intracranial Hemorrhage, TraumaticF7
Intracranial HemorrhagesF7 , Plat
Intracranial ThrombosisPlat
Ischemic Attack, TransientF12 , Plat
Joint InstabilityCol1a1
KeloidCol1a1 , Fgg
KeratoconusFga
Kidney CalculiF2
Kidney DiseasesF7 , Fga
Kidney Failure, ChronicCol1a1 , F2 , F5 , Fgb
Kidney Reperfusion InjuryF3 , Fga , Fgb , Fgg
Leishmaniasis, CutaneousCol1a1
Leukemia, Myeloid, AcuteF3
Leukemia, Promyelocytic, AcuteF3 , Plat
LeukopeniaPlat
LipodermatosclerosisCol1a1
Liver CirrhosisCol1a1 , F2 , F3 , F5 , Klkb1
Liver Cirrhosis, BiliaryCol1a1
Liver Cirrhosis, ExperimentalCol1a1 , F5 , Fgg , Plat , Plg
Liver FailureF2
Liver Failure, AcuteFga
Liver InjuryFgg
Liver NeoplasmsCol1a1
Liver Neoplasms, ExperimentalF12
Liver Reperfusion InjuryF3 , Fga
Low Back PainPlat
Lupus Erythematosus, SystemicF2 , Klkb1
Lupus NephritisCol1a1 , Klkb1
MeningoencephalitisPlat
Mesenteric IschemiaF2 , F5
Mesothelioma, MalignantF9
Metabolic Syndrome XF3 , Plat
Mouth NeoplasmsFga
Multiple MyelomaFgg
Multiple Organ FailurePlat
Multiple SclerosisCol1a1
Myeloproliferative DisordersF3
Myocardial InfarctionCol1a1 , F10 , F12 , F13a1 , F2 , F3 , F5 , F7 , Fgb , Plat
Myocardial IschemiaF3 , F5
MyocarditisCol1a1
MyopiaCol1a1
NeointimaF3
Neoplasm MetastasisF2
Neoplasms, Glandular and EpithelialF7
Nephrogenic Fibrosing DermopathyCol1a1
NephrolithiasisF2
NephrosisF2
Nephrotic SyndromeCol1a1 , F3
Nerve DegenerationF2 , Plat
Neurotoxicity SyndromesPlat
Non-alcoholic Fatty Liver DiseaseCol1a1 , F2
Noonan SyndromeF11
ObesityF2 , F7 , Fgg , Plat
Ocular HypertensionCol1a1
OI/EDS Combined SyndromeCol1a1
Optic Neuropathy, IschemicF5
Oral Submucous FibrosisCol1a1
OsteoarthritisCol1a1
Osteoarthritis, ExperimentalCol1a1
Osteoarthritis, HipCol1a1
Osteoarthritis, KneeF2
Osteogenesis ImperfectaCol1a1
Osteogenesis Imperfecta, Type 2ACol1a1
Osteogenesis Imperfecta, Type 2CCol1a1
Osteogenesis Imperfecta, Type 3Col1a1
Osteogenesis Imperfecta, Type 4Col1a1
Osteopenic Nonfracture SyndromeCol1a1
OsteoporosisCol1a1 , Fga , Fgb
OtosclerosisCol1a1
Ovarian Hyperstimulation SyndromeF3
Ovarian NeoplasmsF2 , F7
Ovary Reperfusion InjuryF3
Pancreatic AdenocarcinomaPlat
PancreatitisFga , Fgb , Fgg
Pancreatitis, AcuteF7
Pancreatitis, ChronicCol1a1
ParatuberculosisF2
ParesisPlat
Parkinson DiseaseFgb
Pediatric Crohn's DiseaseF2
Pemphigoid, BullousF2
Pericardial EffusionPlat
Peritoneal FibrosisF10 , F3 , F5
PeritonitisPlat
Plasminogen Deficiency, Type IPlg
Pneumonia, BacterialF2
Postoperative ComplicationsF7
Pre-EclampsiaF2 , F3 , F5
Precursor B-Cell Lymphoblastic Leukemia-LymphomaF13a1 , F3
Precursor Cell Lymphoblastic Leukemia-LymphomaF3 , Fga
Prekallikrein DeficiencyKlkb1
Prenatal Cortical Hyperostosis, LethalCol1a1
Preterm Premature Rupture of the MembranesF3
Prostatic NeoplasmsCol1a1 , F2 , F5
ProteinuriaF7
Prothrombin Deficiency, CongenitalF2
Pseudoxanthoma Elasticum-Like Disorder with Multiple Coagulation Factor DeficiencyGgcx
Pulmonary Disease, Chronic ObstructiveCol1a1 , F2
Pulmonary EmbolismF13a1 , F2 , F5 , Fga , Fgb , Fgg , Klkb1 , Plat
Pulmonary EmphysemaFga
Pulmonary FibrosisCol1a1 , F2 , F5
Purpura, Schoenlein-HenochPlat
Purpura, Thrombocytopenic, IdiopathicPlat
Purpura, Thrombotic ThrombocytopenicF3
Reperfusion InjuryF2 , Plat
Respiratory Distress Syndrome, AdultF3
Respiratory InsufficiencyPlat
Retinal Artery OcclusionF5
Retinal Vein OcclusionF2 , F5
Rhinitis, AllergicF2
Rhinitis, Allergic, SeasonalFga
Sagittal Sinus ThrombosisF5
Sciatic NeuropathyPlat
Scleroderma, SystemicCol1a1 , F2
SepsisF11 , F2 , F3 , F5 , F7 , F9 , Fga , Klkb1 , Plat
Septic PeritonitisF5
Shock, CardiogenicPlat
Shock, HemorrhagicF2 , F8
Sinus Thrombosis, IntracranialF2
Skin Diseases, VascularF2
Smith-Magenis SyndromeCol1a1
Smoke Inhalation InjuryF7
Snake BitesF3
Spinal Cord CompressionPlat
Spinal Cord InjuriesF2
Status EpilepticusPlat
Stomach NeoplasmsFgg
Stomach UlcerF13a1
StrokeF12 , F13a1 , F2 , F5 , F8 , Fgb , Fgg , Plat , Vkorc1
Systemic Inflammatory Response SyndromeF3
Tendon InjuriesCol1a1
ThrombocytopeniaF7 , Fga
ThromboembolismF12 , F2 , F3 , F5 , F7 , F8 , Plat
ThrombophiliaF13a1 , F2 , F3 , F5 , F8 , Fga , Plg
Thrombophilia due to Activated Protein C ResistanceF5
Thrombophilia, Familial, due to Decreased Release of Tissue Plasminogen ActivatorPlat
Thrombophilia, HereditaryF5
Thrombophilia, X-Linked, Due To Factor Ix DefectF9
ThrombosisF10 , F11 , F2 , F3 , F5 , F9 , Fga , Fgb , Klkb1 , Plat
Thrombotic MicroangiopathiesF3 , Fgg
Trachomatous TrichiasisCol1a1
Transplant RejectionPlat
Ureteral ObstructionCol1a1
Urinary Bladder Neck ObstructionCol1a1
Urinary Bladder NeoplasmsF2
Urinary CalculiF2
UrolithiasisGgcx
UrticariaF12 , F2
Uterine HemorrhageF13a1
Vascular DiseasesVkorc1
Vasospasm, IntracranialPlat
Venous ThromboembolismF2 , F5 , Fga , Plat
Venous ThrombosisF11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , Fga , Plat , Plg
Ventricular Dysfunction, LeftF2 , Plat
Ventricular FibrillationF2
Viral MyocarditisF3
Vitamin K Deficiency BleedingGgcx
Vitamin K-Dependent Clotting Factors, Combined Deficiency Of, 1Ggcx
Vitamin K-Dependent Clotting Factors, Combined Deficiency of, 2Vkorc1
von Willebrand Disease, Type 1Plat
von Willebrand DiseasesF3
Warfarin SensitivityF9 , Vkorc1
Wounds and InjuriesPlat
Pathway Annotations Associated with Genes in the warfarin pharmacodynamics pathway
Pathway TermsGene Symbols
acenocoumarol pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
alteplase pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
aminocaproic acid pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
anistreplase pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
aprotinin pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
argatroban pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
bivalirudin pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
cell-extracellular matrix signaling pathwayCol1a1
coagulation cascade pathwayF10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Klkb1 , Plat , Plg
complement system pathwayF10 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Klkb1 , Plat , Plg
dicoumarol pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
enoxaparin pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
Entamoeba histolyca infection pathwayCol1a1
ephrin - ephrin receptor bidirectional signaling axisFga , Fgb , Fgg
fibrinolysis pathwayFga , Fgb , Fgg , Plat , Plg
fondaparinux pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
forkhead class A signaling pathwayF2
heparin pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
influenza A virus infection pathwayPlg
interleukin-4 signaling pathwayCol1a1
interleukin-6 signaling pathwayFgg
kallikrein-kinin cascade pathwayF12 , Klkb1
phenindione pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
protease mediated signaling via protease-activated receptor 1F2
protease mediated signaling via protease-activated receptor 2F10
protease mediated signaling via protease-activated receptor 3F2
protease mediated signaling via protease-activated receptor 4F2
protein C anticoagulant pathwayF2 , F5
reteplase pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
Staphylococcus aureus infection pathwayFgg , Plg
syndecan signaling pathwayCol1a1 , F2 , Plg
tranexamic acid pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1
vitamin K cycle pathwayGgcx , Vkorc1
vitamin K metabolic pathwayF2 , Ggcx , Vkorc1
warfarin pharmacodynamics pathwayCol1a1 , F10 , F11 , F12 , F13a1 , F13b , F2 , F3 , F5 , F7 , F8 , F9 , Fga , Fgb , Fgg , Ggcx , Klkb1 , Plat , Plg , Vkorc1

References Associated with the warfarin pharmacodynamics pathway:

Ontology Path Diagram:

paths to the root

Import into Pathway Studio: