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Gene: Fundc1 (FUN14 domain containing 1) Rattus norvegicus

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Symbol:

Fundc1

Name:

FUN14 domain containing 1

RGD ID:

1563372

Description:

Predicted to be involved in mitochondrial fusion; mitophagy; and response to hypoxia. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial outer membrane. Orthologous to human FUNDC1 (FUN14 domain containing 1); PARTICIPATES IN mitochondrial autophagy pathway; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

FUN14 domain-containing protein 1; MGC109382

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FUNDC1 (FUN14 domain containing 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Fundc1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fundc1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FUNDC1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FUNDC1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fundc1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FUNDC1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FUNDC1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Fundc1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Fundc1 (FUN14 domain containing 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	FUNDC1 (FUN14 domain containing 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Fundc1 (FUN14 domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fundc1 (FUN14 domain containing 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12511	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	fndc-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Caenorhabditis elegans (roundworm):	fndc-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG5676	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG5676	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fundc1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fundc1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	7,666,787 - 7,683,443 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	7,666,759 - 7,683,441 (+)	Ensembl				GRCr8
mRatBN7.2	X	5,083,635 - 5,100,293 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	5,083,617 - 5,100,284 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	5,136,794 - 5,153,466 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	8,612,588 - 8,629,261 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	4,932,812 - 4,949,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	5,549,468 - 5,566,125 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	5,549,419 - 5,566,127 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	6,329,908 - 6,346,565 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	16,672,818 - 16,689,475 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	5,589,536 - 5,606,194 (+)	NCBI		Celera
Cytogenetic Map	X	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hypoxia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

berberine (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

cadmium atom (EXP,ISO)

cadmium dichloride (ISO)

chloroquine (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

doxorubicin (EXP,ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

hexadecanoic acid (EXP,ISO)

melatonin (EXP)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

nickel atom (ISO)

nickel dichloride (ISO)

nitrates (ISO)

paracetamol (EXP,ISO)

propiconazole (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

valproic acid (ISO)

verteporfin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagy (IEA)

autophagy of mitochondrion (IBA,IEA,ISO,ISS)

mitochondrial fusion (IEA,ISO)

mitophagy (IEA,ISO)

response to hypoxia (IEA,ISO,ISS)

Cellular Component

mitochondrial outer membrane (IBA,IEA,ISO,ISS)

mitochondrion (ISO)

Molecular Function

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

mitochondrial autophagy pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Prolyl-4-Hydroxylases Inhibitor Stabilizes HIF-1a and Increases Mitophagy to Reduce Cell Death After Experimental Retinal Detachment.	Liu H, etal., Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1807-15. doi: 10.1167/iovs.15-18066.
3.	Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells.	Liu L, etal., Nat Cell Biol. 2012 Jan 22;14(2):177-85. doi: 10.1038/ncb2422.
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8.	Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses.	Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
9.	Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury.	Zhang W, etal., Elife. 2016 Dec 20;5. pii: e21407. doi: 10.7554/eLife.21407.

Additional References at PubMed

PMID:15489334	PMID:33106833	PMID:34115550	PMID:34800366	PMID:38584135

Genomics

Comparative Map Data

Fundc1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	7,666,787 - 7,683,443 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	7,666,759 - 7,683,441 (+)	Ensembl				GRCr8
mRatBN7.2	X	5,083,635 - 5,100,293 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	5,083,617 - 5,100,284 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	5,136,794 - 5,153,466 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	8,612,588 - 8,629,261 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	4,932,812 - 4,949,480 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	5,549,468 - 5,566,125 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	5,549,419 - 5,566,127 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	6,329,908 - 6,346,565 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	16,672,818 - 16,689,475 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	5,589,536 - 5,606,194 (+)	NCBI		Celera
Cytogenetic Map	X	q11	NCBI

FUNDC1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	44,523,639 - 44,542,859 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	44,523,639 - 44,542,972 (-)	Ensembl			hg38	GRCh38
GRCh37	X	44,382,885 - 44,402,105 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	44,267,847 - 44,287,160 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	44,139,158 - 44,158,470	NCBI
Celera	X	48,519,971 - 48,539,287 (-)	NCBI		Celera
Cytogenetic Map	X	p11.3	NCBI
HuRef	X	42,105,885 - 42,125,812 (-)	NCBI		HuRef
CHM1_1	X	44,415,841 - 44,435,193 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	43,930,462 - 43,949,676 (-)	NCBI		T2T-CHM13v2.0

Fundc1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	17,386,206 - 17,438,600 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	17,422,803 - 17,438,564 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	17,519,967 - 17,572,329 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	17,556,564 - 17,572,325 (-)	Ensembl			mm10	GRCm38
MGSCv37	X	17,133,695 - 17,149,423 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	16,713,528 - 16,729,256 (-)	NCBI		MGSCv36	mm8
Celera	X	15,168,138 - 15,183,866 (-)	NCBI		Celera
Cytogenetic Map	X	A1.2	NCBI
cM Map	X	12.8	NCBI

Fundc1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955516	3,648,629 - 3,664,032 (+)	Ensembl
ChiLan1.0	NW_004955516	3,648,629 - 3,664,032 (+)	NCBI	ChiLan1.0	ChiLan1.0

FUNDC1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	46,169,288 - 46,188,398 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	46,172,661 - 46,191,723 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	36,970,051 - 36,989,276 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	44,790,550 - 44,809,318 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	44,790,550 - 44,809,793 (-)	Ensembl			panPan2	panpan1.1

FUNDC1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	38,492,470 - 38,505,512 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	38,492,720 - 38,505,424 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	25,720,234 - 25,733,280 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	38,581,261 - 38,594,306 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	38,577,447 - 38,594,178 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	38,614,716 - 38,627,760 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	38,594,940 - 38,607,984 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	38,693,558 - 38,706,604 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Fundc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	30,803,266 - 30,816,345 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936502	10,643,071 - 10,657,134 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936502	10,643,172 - 10,657,118 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FUNDC1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	39,724,998 - 39,737,532 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	39,726,194 - 39,737,663 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	44,109,888 - 44,121,363 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FUNDC1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	41,685,945 - 41,705,037 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666076	6,906,483 - 6,926,162 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fundc1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624887	626,321 - 641,293 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624887	626,321 - 641,296 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Fundc1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	4,663,804 - 4,679,310 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Fundc1
58 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	927
Count of miRNA genes:	316
Interacting mature miRNAs:	421
Transcripts:	ENSRNOT00000004676
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70165	Bp64	Blood pressure QTL 64	5.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	4001493	44939387	Rat
731181	Uae27	Urinary albumin excretion QTL 27	2.7	0.0059	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	X	1970440	46970440	Rat
70166	Bp65	Blood pressure QTL 65	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	X	4001493	14046933	Rat
634325	Bw13	Body weight QTL 13	0		body mass (VT:0001259)	body weight (CMO:0000012)	X	4001493	24470521	Rat

Markers in Region

RH132006

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	5,099,997 - 5,100,194 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	5,565,830 - 5,566,026	NCBI	Rnor6.0
Rnor_5.0	X	6,346,270 - 6,346,466	UniSTS	Rnor5.0
RGSC_v3.4	X	16,689,180 - 16,689,376	UniSTS	RGSC3.4
Celera	X	5,605,899 - 5,606,095	UniSTS
Cytogenetic Map	X	q12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001025027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098157	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ215111	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004676 ⟹ ENSRNOP00000004676

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	7,666,759 - 7,683,441 (+)	Ensembl
mRatBN7.2 Ensembl	X	5,083,756 - 5,100,284 (+)	Ensembl
Rnor_6.0 Ensembl	X	5,549,419 - 5,566,127 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094309 ⟹ ENSRNOP00000092608

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	7,666,759 - 7,682,082 (+)	Ensembl
mRatBN7.2 Ensembl	X	5,083,617 - 5,098,932 (+)	Ensembl

RefSeq Acc Id:

NM_001025027 ⟹ NP_001020198

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	7,666,787 - 7,683,443 (+)	NCBI
mRatBN7.2	X	5,083,635 - 5,100,293 (+)	NCBI
Rnor_6.0	X	5,549,468 - 5,566,125 (+)	NCBI
Rnor_5.0	X	6,329,908 - 6,346,565 (+)	NCBI
RGSC_v3.4	X	16,672,818 - 16,689,475 (+)	RGD
Celera	X	5,589,536 - 5,606,194 (+)	RGD

Sequence:

show sequence

GTGTGAGTGAGCGTGTGGAGGAGGAGGCGGAGGAAAACGAGAGACCATAGACTTCCACCTCGGC
CTAGAGCGTCCTTTAAAGTGTTGGGGAGAGGCGGGCGGGGACCACCCACAACTGGCCGCTGGCG
GTATCATGGCGTCCCGGAACCCCCCTCCCCAAGACTATGAGAGCGATGACGAGTCTTACGAAGT
GTTGGATTTAACTGAGTATGCAAGAAGACACCACTGGTGGAATCGTGTATTTGGCCACAGTTCC
GGACCTATGGTAGAAAAATACTCAGTAGCTACCCAGATAGTAATGGGTGGCGTGACTGGCTGGT
GTGCAGGATTTTTATTCCAAAAGGTTGGAAAACTTGCTGCAACTGCAGTAGGTGGTGGTTTTCT
TCTTCTACAGGTTGCCAGTCACAGTGGCTATGTGCAGATCGACTGGAAGAGAGTTGAAAAAGAT
GTAAACAAAGCAAAAAGACAGATTAAGAAGCGAGCAAATAAGGCAGCACCTGAAATCAACAATA
TAATTGAAGAAGCAACAGACTTTATCAAGCAGAACATTGTGATATCCAGCGGCTTCGTGGGAGG
CTTTTTGCTAGGCCTGGCATCTTAAGGACTTGGAGACTCCATGGTAGTGAATCCAACAGTGAGA
GGAAGACTGTGGCAGCAGGGTGATCTCTCAATGGCTACCAAAGTCTCCAGAGAAAGGAACAGCC
AGCTGGACAATTGCAAATGCAACAGCTTAGCACTTTGCCACCTGAAGCTTAACAAGCTAGTATC
TGCTGTAAGACAACCTATGTGGCGTGTAACCAATTGTATTCTTAGCAAATCATGGATTTTTGCA
AATTTTTAAATTTGCATTTGTTTAGAAACTAGCCTCTGATTATCAGCACTGGATATATTGGAGA
CAGAAAAAGTTCATATGTGTACTGTCCAATGAAATATTACCCTGTCTTCTTTTCAAAGTTCTTT
GTGTTTTACTGTCTAGTACCAATAATTAAAAATTGTCTTATAGCTTCAATATTATGGCTGACTT
TTTTTAAAAGATGCATTTGCAATAATGAAGAATTGTTTTACCCCTTTGTGGAAAGTAACAGTAG
AATTATTAAGATATTAATTCTTCTGATGTATCAATCTTTAGGTTTATTCCCCCTTCTGCTTCTT
ACTTTGCCTATGTGTAATCTTTACATTAAAGAAGGCTTTCGTAAAGAAATACTTCATGCCTAAA
ACACTTTCCCCTTCTCTAATATCTACAGATTTTAAGATGTTTCCTTCAACGTTCTAGTTTTTCA
GATTTGTTTGATTTATTTATCCCTGATAGCTTAGATAGAACTAATTTGGGAGTATGTTATTAGT
TGGGACATTGATATGCTTTATTAATTTCAGATGCATCTCATTTTTTATTTCTAAAAATCCTAAT
TCTTTTTTTTTGGCCTCTTCATCAAAAGGTACAAGCTATGAATTTATTGTCTGAAGAACTGTGA
TTTTCTGTGTAGTTATAAAATTATAGCTTAAATATAATTGCTTCCTTGATTATGTTATGTAAGC
ACTAGGGCTCTCACACATTGCTAGTGTTATGCTACTTGAATACTAGGTCAGTTTACTTTGTTTC
TCTGGGCCAGCCTCACACTTATTCCGAGCATCTCTTTTCCAAAGACAGCTTTCAGTATTGTTAT
TGTTGTTCACAGAATTCTAGGTTATCCCCGGGGAGAACAGCAGAACAGTATAGGTTAGAATCTT
CAGACTGAAAATATTGTAGCTATTCAGACTATGTCTCTATCATAGGAAGCTCCCATTGTATATT
CTGTGTCTTGTAAATGTGTCATTTCATATTTTTGATATTGGTTATAAGCTGTGTGTGTTGTGCT
GTCTTGAACTTCTTTAAACTCAAGTGTGTGATTGAATTTGAGTTTCTTTTATTCTCATTAGTGC
CTCATATAGAATGCTAAATAAAACTCAGTTTCTTAATATGAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001020198	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91353	(Get FASTA)	NCBI Sequence Viewer
	EDL97670	(Get FASTA)	NCBI Sequence Viewer
	EDL97671	(Get FASTA)	NCBI Sequence Viewer
	EDL97672	(Get FASTA)	NCBI Sequence Viewer
	EDL97673	(Get FASTA)	NCBI Sequence Viewer
	EDL97674	(Get FASTA)	NCBI Sequence Viewer
	EDL97675	(Get FASTA)	NCBI Sequence Viewer
	EDL97676	(Get FASTA)	NCBI Sequence Viewer
	EDL97677	(Get FASTA)	NCBI Sequence Viewer
	EDL97678	(Get FASTA)	NCBI Sequence Viewer
	EDL97679	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004676
	ENSRNOP00000004676.5
GenBank Protein	Q5BJS4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001020198 ⟸ NM_001025027
- UniProtKB:	Q5BJS4 (UniProtKB/Swiss-Prot), A6JZV7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASRNPPPQDYESDDESYEVLDLTEYARRHHWWNRVFGHSSGPMVEKYSVATQIVMGGVTGWCA GFLFQKVGKLAATAVGGGFLLLQVASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEINNII EEATDFIKQNIVISSGFVGGFLLGLAS hide sequence

Ensembl Acc Id:

ENSRNOP00000004676 ⟸ ENSRNOT00000004676

Ensembl Acc Id:

ENSRNOP00000092608 ⟸ ENSRNOT00000094309

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BJS4-F1-model_v2	AlphaFold	Q5BJS4	1-155	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563372	AgrOrtholog
BioCyc Gene	G2FUF-3122	BioCyc
Ensembl Genes	ENSRNOG00000003470	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000004676	ENTREZGENE
	ENSRNOT00000004676.7	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7317238	IMAGE-MGC_LOAD
InterPro	FUN14	UniProtKB/Swiss-Prot
KEGG Report	rno:363442	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:109382	IMAGE-MGC_LOAD
NCBI Gene	363442	ENTREZGENE
PANTHER	FUN14 DOMAIN-CONTAINING PROTEIN 1	UniProtKB/Swiss-Prot
	PTHR21346	UniProtKB/Swiss-Prot
Pfam	FUN14	UniProtKB/Swiss-Prot
PhenoGen	Fundc1	PhenoGen
RatGTEx	ENSRNOG00000003470	RatGTEx
UniProt	A0A8I6GJV7_RAT	UniProtKB/TrEMBL
	A6JZV7	ENTREZGENE, UniProtKB/TrEMBL
	A6JZV8_RAT	UniProtKB/TrEMBL
	A6JZV9_RAT	UniProtKB/TrEMBL
	A6JZW1_RAT	UniProtKB/TrEMBL
	A6JZW4_RAT	UniProtKB/TrEMBL
	A6JZW5_RAT	UniProtKB/TrEMBL
	FUND1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-02-09	Fundc1	FUN14 domain containing 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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RGD Manual Annotations