Symbol:
Itgav
Name:
integrin subunit alpha V
RGD ID:
1310613
Description:
Enables signaling receptor binding activity. Involved in several processes, including blood vessel morphogenesis; positive regulation of cell population proliferation; and positive regulation of cytosolic calcium ion concentration. Predicted to be located in several cellular components, including cell projection membrane; cell surface; and focal adhesion. Predicted to be part of alphav-beta3 integrin-HMGB1 complex; alphav-beta3 integrin-IGF-1-IGF1R complex; and integrin complex. Predicted to be active in external side of plasma membrane. Used to study corneal neovascularization; coronary stenosis; and ischemia. Biomarker of hypertension. Human ortholog(s) of this gene implicated in abdominal aortic aneurysm and acute myeloid leukemia. Orthologous to human ITGAV (integrin subunit alpha V); PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
Cd51; Dnmt3l-ps1 pseudogene; integrin alpha V ; integrin alpha-V; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ITGAV (integrin subunit alpha V)
HGNC
HomoloGene, NCBI
Mus musculus (house mouse):
Itgav (integrin alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Itgav (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ITGAV (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ITGAV (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Itgav (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ITGAV (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
ITGAV (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Itgav (integrin subunit alpha V)
Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
GAD2 (glutamate decarboxylase 2)
HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
ITGAV (integrin subunit alpha V)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Itgav (integrin alpha V)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
itgav (integrin, alpha V)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
pat-2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
if
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):
itgav
Alliance
DIOPT (Ensembl Compara|OMA|OrthoFinder|PANTHER)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 89,245,382 - 89,333,512 (+) NCBI GRCr8 mRatBN7.2 3 68,838,514 - 68,926,653 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 68,838,189 - 68,926,639 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 72,233,903 - 72,315,469 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 80,832,555 - 80,914,128 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 78,567,077 - 78,655,183 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 71,113,269 - 71,205,958 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 71,114,100 - 71,202,411 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 77,643,270 - 77,731,358 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 66,953,403 - 67,029,774 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 66,848,789 - 66,926,146 (+) NCBI Celera 3 68,209,136 - 68,297,332 (+) NCBI Celera Cytogenetic Map 3 q24 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Itgav Rat (-)-epigallocatechin 3-gallate decreases expression ISO ITGAV (Homo sapiens) 6480464 epigallocatechin gallate results in decreased expression of ITGAV mRNA CTD PMID:16084531 Itgav Rat (R)-adrenaline increases expression ISO ITGAV (Homo sapiens) 6480464 Epinephrine results in increased expression of ITGAV mRNA CTD PMID:12729923 Itgav Rat (S)-nicotine increases expression ISO Itgav (Mus musculus) 6480464 Nicotine results in increased expression of ITGAV mRNA CTD PMID:17997037 Itgav Rat 1-chloro-2,4-dinitrobenzene affects expression ISO Itgav (Mus musculus) 6480464 Dinitrochlorobenzene affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ITGAV mRNA CTD PMID:30723492 Itgav Rat 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ITGAV mRNA CTD PMID:29097150 Itgav Rat 17beta-estradiol increases expression ISO Itgav (Mus musculus) 6480464 Estradiol results in increased expression of ITGAV mRNA CTD PMID:19484750 Itgav Rat 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of ITGAV mRNA CTD PMID:32145629 Itgav Rat 17beta-estradiol multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of ITGAV mRNA CTD PMID:30165855 Itgav Rat 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO ITGAV (Homo sapiens) 6480464 Dihydrotestosterone results in increased expression of ITGAV mRNA CTD PMID:29581250 Itgav Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ITGAV mRNA CTD PMID:33387578 Itgav Rat 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2 more ... CTD PMID:32109520 Itgav Rat 2,6-dimethoxyphenol multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of ITGAV protein CTD PMID:38598786 Itgav Rat 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of ITGAV mRNA CTD PMID:21346803 Itgav Rat 2-bromohexadecanoic acid multiple interactions ISO ITGAV (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ITGAV protein] CTD PMID:38195004 Itgav Rat 3,4-methylenedioxymethamphetamine decreases expression ISO Itgav (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of ITGAV mRNA CTD PMID:26251327 Itgav Rat 4-hydroxyphenyl retinamide increases expression ISO Itgav (Mus musculus) 6480464 Fenretinide results in increased expression of ITGAV mRNA CTD PMID:28973697 Itgav Rat 4-vinylcyclohexene dioxide affects expression ISO Itgav (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of ITGAV mRNA CTD PMID:20829426 Itgav Rat 5-fluorouracil affects response to substance ISO ITGAV (Homo sapiens) 6480464 ITGAV protein affects the susceptibility to Fluorouracil CTD PMID:16217747 Itgav Rat acrolein multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of ITGAV mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of ITGAV mRNA CTD PMID:32699268 Itgav Rat acrylamide decreases expression EXP 6480464 Acrylamide results in decreased expression of ITGAV mRNA CTD PMID:22197712 Itgav Rat aflatoxin B1 affects expression ISO ITGAV (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of ITGAV protein CTD PMID:20106945 Itgav Rat aflatoxin B1 increases methylation ISO ITGAV (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of ITGAV gene CTD PMID:27153756 and PMID:28458013 Itgav Rat aldehydo-D-glucose decreases expression ISO ITGAV (Homo sapiens) 6480464 Glucose results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat all-trans-retinoic acid multiple interactions ISO ITGAV (Homo sapiens) 6480464 Tretinoin results in increased cleavage of [ITGAV protein binds to ITGB1 protein] and Tretinoin results in increased expression of [ITGAV protein binds to ITGB1 protein] CTD PMID:11369141 and PMID:11718225 Itgav Rat all-trans-retinoic acid multiple interactions ISO Itgav (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of ITGAV mRNA CTD PMID:30951980 Itgav Rat alpha-hexylcinnamaldehyde affects expression ISO Itgav (Mus musculus) 6480464 hexyl cinnamic aldehyde affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat alpha-pinene multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of ITGAV mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of ITGAV mRNA CTD PMID:32699268 Itgav Rat Arg-Gly-Asp multiple interactions ISO ITGAV (Homo sapiens) 6480464 arginyl-glycyl-aspartic acid inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 Itgav Rat aristolochic acid A decreases expression ISO ITGAV (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of ITGAV mRNA CTD PMID:33212167 Itgav Rat arsenite(3-) decreases expression ISO Itgav (Mus musculus) 6480464 arsenite results in decreased expression of ITGAV mRNA CTD PMID:18191166 Itgav Rat arsenous acid multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ITGAV mRNA CTD PMID:25913414 Itgav Rat benzo[a]pyrene multiple interactions ISO ITGAV (Homo sapiens) 6480464 Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased expression of [ITGAV protein binds to ITGB3 protein]] and Benzo(a)pyrene inhibits the reaction [FGF2 protein results in increased expression of ITGAV protein] CTD PMID:20876236 Itgav Rat benzo[a]pyrene increases methylation ISO ITGAV (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ITGAV promoter CTD PMID:27901495 Itgav Rat benzo[a]pyrene increases expression ISO ITGAV (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of ITGAV mRNA CTD PMID:26238291 and PMID:32234424 Itgav Rat bisphenol A increases expression ISO Itgav (Mus musculus) 6480464 bisphenol A results in increased expression of ITGAV mRNA CTD PMID:26063408 Itgav Rat bisphenol A decreases expression ISO ITGAV (Homo sapiens) 6480464 bisphenol A results in decreased expression of ITGAV protein CTD PMID:34186270 Itgav Rat bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of ITGAV mRNA CTD PMID:32145629 Itgav Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ITGAV mRNA CTD PMID:29097150 Itgav Rat bisphenol AF increases expression ISO ITGAV (Homo sapiens) 6480464 bisphenol AF results in increased expression of ITGAV protein CTD PMID:34186270 Itgav Rat Bisphenol B increases expression ISO ITGAV (Homo sapiens) 6480464 bisphenol B results in increased expression of ITGAV protein CTD PMID:34186270 Itgav Rat bisphenol F multiple interactions ISO Itgav (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of ITGAV mRNA CTD PMID:30951980 Itgav Rat bortezomib multiple interactions ISO ITGAV (Homo sapiens) 6480464 [arsenic trioxide co-treated with Bortezomib] results in decreased expression of ITGAV mRNA CTD PMID:25913414 Itgav Rat bortezomib increases expression ISO ITGAV (Homo sapiens) 6480464 Bortezomib results in increased expression of ITGAV mRNA CTD PMID:20471514 Itgav Rat butane-2,3-dione decreases expression ISO ITGAV (Homo sapiens) 6480464 Diacetyl results in decreased expression of ITGAV protein CTD PMID:34031698 Itgav Rat cadmium atom multiple interactions ISO ITGAV (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ITGAV protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ITGAV protein CTD PMID:38195004 Itgav Rat cadmium dichloride decreases expression ISO ITGAV (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of ITGAV protein CTD PMID:24527689 Itgav Rat cadmium dichloride multiple interactions ISO ITGAV (Homo sapiens) 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ITGAV protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of ITGAV protein CTD PMID:38195004 Itgav Rat cadmium dichloride increases expression ISO ITGAV (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of ITGAV mRNA CTD PMID:38382870 Itgav Rat cannabidiol multiple interactions ISO ITGAV (Homo sapiens) 6480464 Cannabidiol inhibits the reaction [ITGB3 protein results in increased expression of ITGAV mRNA] and Cannabidiol inhibits the reaction [TNF protein results in increased expression of ITGAV mRNA] CTD PMID:31250491 Itgav Rat carbamazepine affects expression ISO ITGAV (Homo sapiens) 6480464 Carbamazepine affects the expression of ITGAV mRNA CTD PMID:25979313 Itgav Rat carbon nanotube increases expression ISO Itgav (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 Itgav Rat CGP 52608 multiple interactions ISO ITGAV (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ITGAV gene] CTD PMID:28238834 Itgav Rat chloropicrin decreases expression ISO ITGAV (Homo sapiens) 6480464 chloropicrin results in decreased expression of ITGAV mRNA CTD PMID:26352163 and PMID:28476498 Itgav Rat chlorpyrifos decreases expression ISO Itgav (Mus musculus) 6480464 Chlorpyrifos results in decreased expression of ITGAV mRNA CTD PMID:37019170 Itgav Rat choline multiple interactions ISO Itgav (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ITGAV and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ITGAV gene CTD PMID:20938992 Itgav Rat cisplatin multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of ITGAV mRNA more ... CTD PMID:25594011 and PMID:27392435 Itgav Rat copper atom multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGAV mRNA more ... CTD PMID:24690739 more ... Itgav Rat copper(0) multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of ITGAV mRNA more ... CTD PMID:24690739 more ... Itgav Rat copper(II) sulfate increases expression ISO ITGAV (Homo sapiens) 6480464 Copper Sulfate results in increased expression of ITGAV mRNA CTD PMID:19549813 Itgav Rat cordycepin increases expression ISO Itgav (Mus musculus) 6480464 cordycepin results in increased expression of ITGAV protein CTD PMID:32042022 Itgav Rat cyclosporin A increases expression ISO ITGAV (Homo sapiens) 6480464 Cyclosporine results in increased expression of ITGAV mRNA CTD PMID:20106945 Itgav Rat cyclosporin A decreases expression ISO ITGAV (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ITGAV mRNA CTD PMID:25562108 Itgav Rat D-glucose decreases expression ISO ITGAV (Homo sapiens) 6480464 Glucose results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat dabrafenib multiple interactions ISO ITGAV (Homo sapiens) 6480464 dabrafenib inhibits the reaction [lipopolysaccharide and Escherichia coli O111 B4 results in increased expression of [ITGAV protein binds to ITGB5 protein]] CTD PMID:29042256 Itgav Rat DDE decreases expression ISO ITGAV (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of ITGAV mRNA CTD PMID:38568856 Itgav Rat diallyl trisulfide decreases expression ISO ITGAV (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of ITGAV protein CTD PMID:28741790 Itgav Rat diarsenic trioxide multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Bortezomib] results in decreased expression of ITGAV mRNA CTD PMID:25913414 Itgav Rat dibutyl phthalate increases expression ISO Itgav (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of ITGAV mRNA CTD PMID:21266533 Itgav Rat dibutyl phthalate decreases expression ISO ITGAV (Homo sapiens) 6480464 Dibutyl Phthalate results in decreased expression of ITGAV mRNA CTD PMID:38944327 Itgav Rat dibutyl phthalate increases expression ISO ITGAV (Homo sapiens) 6480464 Dibutyl Phthalate results in increased expression of ITGAV mRNA CTD PMID:34902519 Itgav Rat disulfiram multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA CTD PMID:24690739 Itgav Rat dorsomorphin multiple interactions ISO ITGAV (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ITGAV mRNA CTD PMID:27188386 Itgav Rat doxorubicin increases expression ISO ITGAV (Homo sapiens) 6480464 Doxorubicin results in increased expression of ITGAV mRNA CTD PMID:37062353 Itgav Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ITGAV mRNA CTD PMID:29391264 Itgav Rat entinostat multiple interactions ISO ITGAV (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ITGAV mRNA CTD PMID:27188386 Itgav Rat entinostat decreases expression ISO ITGAV (Homo sapiens) 6480464 entinostat results in decreased expression of ITGAV mRNA CTD PMID:26272509 Itgav Rat ethanol decreases expression ISO Itgav (Mus musculus) 6480464 Ethanol results in decreased expression of ITGAV mRNA CTD PMID:29018328 Itgav Rat ethanol affects expression ISO Itgav (Mus musculus) 6480464 Ethanol affects the expression of ITGAV mRNA CTD PMID:30319688 Itgav Rat ethyl methanesulfonate increases expression ISO ITGAV (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of ITGAV mRNA CTD PMID:23649840 Itgav Rat fenamidone increases expression ISO Itgav (Mus musculus) 6480464 fenamidone results in increased expression of ITGAV mRNA CTD PMID:27029645 Itgav Rat fenhexamid increases expression ISO ITGAV (Homo sapiens) 6480464 N-(2 and 3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of ITGAV mRNA CTD PMID:25461557 Itgav Rat folic acid multiple interactions ISO Itgav (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ITGAV and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ITGAV gene CTD PMID:20938992 Itgav Rat formaldehyde increases expression ISO ITGAV (Homo sapiens) 6480464 Formaldehyde results in increased expression of ITGAV mRNA CTD PMID:23649840 Itgav Rat FR900359 increases phosphorylation ISO ITGAV (Homo sapiens) 6480464 FR900359 results in increased phosphorylation of ITGAV protein CTD PMID:37730182 Itgav Rat furfural multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of ITGAV protein CTD PMID:38598786 Itgav Rat gallic acid decreases expression ISO ITGAV (Homo sapiens) 6480464 Gallic Acid results in decreased expression of ITGAV protein CTD PMID:38100242 Itgav Rat gefitinib multiple interactions ISO Itgav (Mus musculus) 6480464 gefitinib inhibits the reaction [TNF protein results in increased expression of ITGAV mRNA] CTD PMID:15841081 Itgav Rat gemcitabine multiple interactions ISO ITGAV (Homo sapiens) 6480464 [ITGB6 co-treated with ITGAV] affects the susceptibility to Gemcitabine CTD PMID:20150628 Itgav Rat genistein decreases expression ISO ITGAV (Homo sapiens) 6480464 Genistein results in decreased expression of ITGAV protein CTD PMID:20884965 Itgav Rat genistein multiple interactions ISO ITGAV (Homo sapiens) 6480464 ESR2 promotes the reaction [Genistein results in decreased expression of ITGAV protein] CTD PMID:20884965 Itgav Rat glucose decreases expression ISO ITGAV (Homo sapiens) 6480464 Glucose results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat glyphosate decreases expression ISO ITGAV (Homo sapiens) 6480464 Glyphosate results in decreased expression of ITGAV mRNA CTD PMID:31295307 Itgav Rat hydrogen peroxide decreases expression ISO ITGAV (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of ITGAV mRNA CTD PMID:12419474 Itgav Rat indometacin increases expression EXP 6480464 Indomethacin results in increased expression of ITGAV mRNA CTD PMID:36868495 Itgav Rat irinotecan decreases expression ISO ITGAV (Homo sapiens) 6480464 Irinotecan metabolite results in decreased expression of ITGAV mRNA and Irinotecan results in decreased expression of ITGAV mRNA CTD PMID:15956246 Itgav Rat isotretinoin increases expression ISO ITGAV (Homo sapiens) 6480464 Isotretinoin results in increased expression of ITGAV mRNA CTD PMID:20436886 Itgav Rat ivermectin decreases expression ISO ITGAV (Homo sapiens) 6480464 Ivermectin results in decreased expression of ITGAV protein CTD PMID:32959892 Itgav Rat L-methionine multiple interactions ISO Itgav (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of ITGAV and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ITGAV gene CTD PMID:20938992 Itgav Rat lead(0) affects expression ISO ITGAV (Homo sapiens) 6480464 Lead affects the expression of ITGAV mRNA CTD PMID:28903495 Itgav Rat lipopolysaccharide increases secretion ISO ITGAV (Homo sapiens) 6480464 Lipopolysaccharides results in increased secretion of ITGAV protein alternative form CTD PMID:27887929 Itgav Rat lipopolysaccharide multiple interactions ISO ITGAV (Homo sapiens) 6480464 Triterpenes inhibits the reaction [Lipopolysaccharides results in increased secretion of ITGAV protein alternative form] CTD PMID:27887929 Itgav Rat LY294002 multiple interactions ISO ITGAV (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 Itgav Rat manganese(II) chloride multiple interactions ISO ITGAV (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] more ... CTD PMID:15213856 Itgav Rat methamphetamine multiple interactions EXP 6480464 [Methamphetamine co-treated with Thyroxine] results in increased expression of ITGAV protein CTD PMID:35301009 Itgav Rat methyl methanesulfonate increases expression ISO ITGAV (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of ITGAV mRNA CTD PMID:23649840 Itgav Rat methyl salicylate affects expression ISO Itgav (Mus musculus) 6480464 methyl salicylate affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat monosodium L-glutamate decreases expression ISO Itgav (Mus musculus) 6480464 Sodium Glutamate results in decreased expression of ITGAV mRNA CTD PMID:22078008 Itgav Rat N-acetyl-L-cysteine decreases expression ISO ITGAV (Homo sapiens) 6480464 Acetylcysteine results in decreased expression of ITGAV mRNA CTD PMID:16084531 Itgav Rat niclosamide multiple interactions ISO ITGAV (Homo sapiens) 6480464 Niclosamide inhibits the reaction [TNFSF11 protein results in increased expression of ITGAV mRNA] CTD PMID:26792726 Itgav Rat nicotine increases expression ISO Itgav (Mus musculus) 6480464 Nicotine results in increased expression of ITGAV mRNA CTD PMID:17997037 Itgav Rat nitrofen increases expression EXP 6480464 nitrofen results in increased expression of ITGAV protein CTD PMID:15119844 Itgav Rat nonanoic acid affects expression ISO Itgav (Mus musculus) 6480464 pelargonic acid affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat ouabain decreases expression ISO ITGAV (Homo sapiens) 6480464 Ouabain results in decreased expression of ITGAV mRNA CTD PMID:28795476 Itgav Rat oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ITGAV mRNA CTD PMID:25729387 Itgav Rat ozone multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of ITGAV mRNA more ... CTD PMID:32699268 Itgav Rat paracetamol decreases expression ISO ITGAV (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ITGAV mRNA CTD PMID:21420995 Itgav Rat perfluorooctane-1-sulfonic acid decreases expression ISO ITGAV (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in decreased expression of ITGAV mRNA CTD PMID:27153767 Itgav Rat phthalaldehyde affects expression ISO Itgav (Mus musculus) 6480464 o-Phthalaldehyde affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat pioglitazone multiple interactions ISO ITGAV (Homo sapiens) 6480464 pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ITGAV mRNA] CTD PMID:20847119 Itgav Rat pirinixic acid multiple interactions ISO Itgav (Mus musculus) 6480464 NCF1 protein promotes the reaction [pirinixic acid results in decreased expression of ITGAV mRNA] CTD PMID:17950772 Itgav Rat pirinixic acid decreases expression ISO Itgav (Mus musculus) 6480464 pirinixic acid results in decreased expression of ITGAV mRNA CTD PMID:17950772 Itgav Rat potassium chromate decreases expression ISO ITGAV (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of ITGAV mRNA CTD PMID:22714537 Itgav Rat Ptaquiloside decreases expression ISO Itgav (Mus musculus) 6480464 ptaquiloside results in decreased expression of ITGAV mRNA CTD PMID:23274088 Itgav Rat quercetin decreases expression ISO ITGAV (Homo sapiens) 6480464 Quercetin results in decreased expression of ITGAV mRNA CTD PMID:21632981 Itgav Rat quercetin multiple interactions EXP 6480464 Quercetin results in decreased expression of [ITGB3 protein binds to ITGAV protein] CTD PMID:28431985 Itgav Rat rebaudioside A decreases expression ISO ITGAV (Homo sapiens) 6480464 rebaudioside A results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat resveratrol multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of ITGAV mRNA more ... CTD PMID:21467134 and PMID:23557933 Itgav Rat rimonabant multiple interactions ISO Itgav (Mus musculus) 6480464 Rimonabant inhibits the reaction [Dietary Fats results in increased expression of ITGAV mRNA] CTD PMID:19030233 Itgav Rat SB 431542 multiple interactions ISO ITGAV (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ITGAV mRNA CTD PMID:27188386 Itgav Rat silver atom decreases expression ISO Itgav (Mus musculus) 6480464 Silver results in decreased expression of ITGAV mRNA CTD PMID:27131904 Itgav Rat silver(0) decreases expression ISO Itgav (Mus musculus) 6480464 Silver results in decreased expression of ITGAV mRNA CTD PMID:27131904 Itgav Rat sirolimus decreases expression ISO Itgav (Mus musculus) 6480464 Sirolimus results in decreased expression of ITGAV mRNA and Sirolimus results in decreased expression of ITGAV protein CTD PMID:19922502 Itgav Rat sodium arsenite increases expression ISO ITGAV (Homo sapiens) 6480464 sodium arsenite results in increased expression of ITGAV mRNA CTD PMID:12016162 and PMID:38568856 Itgav Rat sodium arsenite affects expression ISO Itgav (Mus musculus) 6480464 sodium arsenite affects the expression of ITGAV mRNA CTD PMID:26674514 Itgav Rat sodium chloride multiple interactions ISO ITGAV (Homo sapiens) 6480464 [Sodium Chloride co-treated with Furaldehyde] results in decreased expression of and affects the localization of ITGAV protein more ... CTD PMID:38598786 Itgav Rat Soman increases expression EXP 6480464 Soman results in increased expression of ITGAV mRNA CTD PMID:19281266 Itgav Rat steviol decreases expression ISO ITGAV (Homo sapiens) 6480464 steviol results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat stevioside decreases expression ISO ITGAV (Homo sapiens) 6480464 stevioside results in decreased expression of ITGAV mRNA CTD PMID:31655124 Itgav Rat streptozocin affects expression ISO Itgav (Mus musculus) 6480464 Streptozocin affects the expression of ITGAV mRNA CTD PMID:26073000 Itgav Rat succimer multiple interactions ISO Itgav (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of ITGAV mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of ITGAV mRNA CTD PMID:21641980 and PMID:26378955 Itgav Rat sucrose multiple interactions EXP 6480464 [Tobacco Smoke Pollution co-treated with Sucrose] results in decreased expression of ITGAV mRNA CTD PMID:27470987 Itgav Rat sucrose decreases expression EXP 6480464 Sucrose results in decreased expression of ITGAV mRNA CTD PMID:27470987 Itgav Rat sunitinib decreases expression ISO ITGAV (Homo sapiens) 6480464 Sunitinib results in decreased expression of ITGAV mRNA CTD PMID:31533062 Itgav Rat tert-butyl hydroperoxide multiple interactions ISO ITGAV (Homo sapiens) 6480464 [rosiglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ITGAV mRNA more ... CTD PMID:20847119 Itgav Rat tert-butyl hydroperoxide increases expression ISO ITGAV (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of ITGAV mRNA CTD PMID:20847119 Itgav Rat testosterone decreases expression ISO ITGAV (Homo sapiens) 6480464 Testosterone results in decreased expression of ITGAV mRNA CTD PMID:33359661 Itgav Rat testosterone enanthate affects expression ISO ITGAV (Homo sapiens) 6480464 testosterone enanthate affects the expression of ITGAV mRNA CTD PMID:17440010 Itgav Rat tetrachloromethane affects expression ISO Itgav (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of ITGAV mRNA CTD PMID:17484886 Itgav Rat tetrachloromethane increases expression ISO Itgav (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of ITGAV mRNA CTD PMID:31919559 Itgav Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of ITGAV mRNA CTD PMID:23411599 Itgav Rat thiram increases expression ISO ITGAV (Homo sapiens) 6480464 Thiram results in increased expression of ITGAV mRNA CTD PMID:38568856 Itgav Rat thyroxine multiple interactions EXP 6480464 [Methamphetamine co-treated with Thyroxine] results in increased expression of ITGAV protein CTD PMID:35301009 Itgav Rat titanium dioxide increases expression ISO ITGAV (Homo sapiens) 6480464 titanium dioxide results in increased expression of ITGAV mRNA CTD PMID:24023007 Itgav Rat titanium dioxide decreases methylation ISO Itgav (Mus musculus) 6480464 titanium dioxide results in decreased methylation of ITGAV gene CTD PMID:35295148 Itgav Rat topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of ITGAV mRNA CTD PMID:25729387 Itgav Rat tranilast decreases expression EXP 329845558 tranilast inhibits the reaction [balloon angioplasty increases mRNA expression in rat carotid artery] RGD Itgav Rat trimellitic anhydride affects expression ISO Itgav (Mus musculus) 6480464 trimellitic anhydride affects the expression of ITGAV mRNA CTD PMID:22302311 Itgav Rat triphenyl phosphate affects expression ISO ITGAV (Homo sapiens) 6480464 triphenyl phosphate affects the expression of ITGAV mRNA CTD PMID:37042841 Itgav Rat troglitazone decreases expression ISO Itgav (Mus musculus) 6480464 troglitazone results in decreased expression of ITGAV mRNA CTD PMID:28973697 Itgav Rat troglitazone multiple interactions ISO ITGAV (Homo sapiens) 6480464 troglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ITGAV mRNA] CTD PMID:20847119 Itgav Rat valproic acid decreases methylation ISO ITGAV (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ITGAV gene CTD PMID:29154799 Itgav Rat valproic acid increases expression ISO ITGAV (Homo sapiens) 6480464 Valproic Acid results in increased expression of ITGAV mRNA CTD PMID:23179753 and PMID:28001369 Itgav Rat wortmannin multiple interactions ISO ITGAV (Homo sapiens) 6480464 wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] CTD PMID:15213856 Itgav Rat zinc atom decreases expression ISO ITGAV (Homo sapiens) 6480464 Zinc results in decreased expression of ITGAV mRNA CTD PMID:19071009 Itgav Rat zinc(0) decreases expression ISO ITGAV (Homo sapiens) 6480464 Zinc results in decreased expression of ITGAV mRNA CTD PMID:19071009
Imported Annotations - PID (archival)
(-)-epigallocatechin 3-gallate (ISO) (R)-adrenaline (ISO) (S)-nicotine (ISO) 1-chloro-2,4-dinitrobenzene (ISO) 1-naphthyl isothiocyanate (EXP) 17alpha-ethynylestradiol (EXP) 17beta-estradiol (EXP,ISO) 17beta-hydroxy-5alpha-androstan-3-one (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP) 2,3,7,8-Tetrachlorodibenzofuran (EXP) 2,6-dimethoxyphenol (ISO) 2,6-dinitrotoluene (EXP) 2-bromohexadecanoic acid (ISO) 3,4-methylenedioxymethamphetamine (ISO) 4-hydroxyphenyl retinamide (ISO) 4-vinylcyclohexene dioxide (ISO) 5-fluorouracil (ISO) acrolein (ISO) acrylamide (EXP) aflatoxin B1 (ISO) aldehydo-D-glucose (ISO) all-trans-retinoic acid (ISO) alpha-hexylcinnamaldehyde (ISO) alpha-pinene (ISO) Arg-Gly-Asp (ISO) aristolochic acid A (ISO) arsenite(3-) (ISO) arsenous acid (ISO) benzo[a]pyrene (ISO) bisphenol A (EXP,ISO) bisphenol AF (ISO) Bisphenol B (ISO) bisphenol F (ISO) bortezomib (ISO) butane-2,3-dione (ISO) cadmium atom (ISO) cadmium dichloride (ISO) cannabidiol (ISO) carbamazepine (ISO) carbon nanotube (ISO) CGP 52608 (ISO) chloropicrin (ISO) chlorpyrifos (ISO) choline (ISO) cisplatin (ISO) copper atom (ISO) copper(0) (ISO) copper(II) sulfate (ISO) cordycepin (ISO) cyclosporin A (ISO) D-glucose (ISO) dabrafenib (ISO) DDE (ISO) diallyl trisulfide (ISO) diarsenic trioxide (ISO) dibutyl phthalate (ISO) disulfiram (ISO) dorsomorphin (ISO) doxorubicin (ISO) endosulfan (EXP) entinostat (ISO) ethanol (ISO) ethyl methanesulfonate (ISO) fenamidone (ISO) fenhexamid (ISO) folic acid (ISO) formaldehyde (ISO) FR900359 (ISO) furfural (ISO) gallic acid (ISO) gefitinib (ISO) gemcitabine (ISO) genistein (ISO) glucose (ISO) glyphosate (ISO) hydrogen peroxide (ISO) indometacin (EXP) irinotecan (ISO) isotretinoin (ISO) ivermectin (ISO) L-methionine (ISO) lead(0) (ISO) lipopolysaccharide (ISO) LY294002 (ISO) manganese(II) chloride (ISO) methamphetamine (EXP) methyl methanesulfonate (ISO) methyl salicylate (ISO) monosodium L-glutamate (ISO) N-acetyl-L-cysteine (ISO) niclosamide (ISO) nicotine (ISO) nitrofen (EXP) nonanoic acid (ISO) ouabain (ISO) oxaliplatin (EXP) ozone (ISO) paracetamol (ISO) perfluorooctane-1-sulfonic acid (ISO) phthalaldehyde (ISO) pioglitazone (ISO) pirinixic acid (ISO) potassium chromate (ISO) Ptaquiloside (ISO) quercetin (EXP,ISO) rebaudioside A (ISO) resveratrol (ISO) rimonabant (ISO) SB 431542 (ISO) silver atom (ISO) silver(0) (ISO) sirolimus (ISO) sodium arsenite (ISO) sodium chloride (ISO) Soman (EXP) steviol (ISO) stevioside (ISO) streptozocin (ISO) succimer (ISO) sucrose (EXP) sunitinib (ISO) tert-butyl hydroperoxide (ISO) testosterone (ISO) testosterone enanthate (ISO) tetrachloromethane (ISO) thioacetamide (EXP) thiram (ISO) thyroxine (EXP) titanium dioxide (ISO) topotecan (EXP) tranilast (EXP) trimellitic anhydride (ISO) triphenyl phosphate (ISO) troglitazone (ISO) valproic acid (ISO) wortmannin (ISO) zinc atom (ISO) zinc(0) (ISO)
1.
Endothelial microparticles and platelet and leukocyte activation in patients with the metabolic syndrome.
Arteaga RB, etal., Am J Cardiol. 2006 Jul 1;98(1):70-4. Epub 2006 May 4.
2.
The oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of alpha(v)beta3 integrins.
Baron W, etal., EMBO J. 2002 Apr 15;21(8):1957-66.
3.
The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
Bonnet S, etal., Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11418-23. Epub 2007 Jun 27.
4.
Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease.
Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
5.
Connection between integrins and cell activation in rat adrenal glomerulosa cells: a role for Arg-Gly-Asp peptide in the activation of the p42/p44(mapk) pathway and intracellular calcium.
Campbell S, etal., Endocrinology. 2003 Apr;144(4):1486-95.
6.
Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis.
Chang Y and Finnemann SC, J Cell Sci. 2007 Sep 1;120(Pt 17):3053-63. Epub 2007 Aug 7.
7.
Acute hyperglycaemia induces changes in the transcription levels of 4 major genes in human endothelial cells: macroarrays-based expression analysis.
Chettab K, etal., Thromb Haemost. 2002 Jan;87(1):141-8.
8.
Beta3-integrin mediates smooth muscle cell accumulation in neointima after carotid ligation in mice.
Choi ET, etal., Circulation. 2004 Mar 30;109(12):1564-9. Epub 2004 Mar 8.
9.
Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines.
Choke E, etal., Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2077-82. Epub 2006 Jun 29.
10.
Vitronectin is up-regulated after vascular injury and vitronectin blockade prevents neointima formation.
Dufourcq P, etal., Cardiovasc Res. 2002 Mar;53(4):952-62.
11.
New vessel formation after surgical brain injury in the rat's cerebral cortex I. Formation of the blood vessels proximally to the surgical injury.
Frontczak-Baniewicz M and Walski M, Acta Neurobiol Exp (Wars). 2003;63(2):65-75.
12.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
13.
Rat ISS GO annotations from GOA human gene data--August 2006
GOA data from the GO Consortium
14.
alphaV integrins are necessary for eutrophic inward remodeling of small arteries in hypertension.
Heerkens EH, etal., Hypertension. 2006 Feb;47(2):281-7. Epub 2005 Dec 27.
15.
Integrins on rat osteoclasts: characterization of two monoclonal antibodies (F4 and F11) to rat beta 3.
Helfrich MH, etal., J Bone Miner Res. 1992 Mar;7(3):345-51.
16.
Integrins: bidirectional, allosteric signaling machines.
Hynes RO Cell 2002 Sep 20;110(6):673-87.
17.
Inhibition of corneal neovascularization by alpha(v)-integrin antagonists in the rat.
Klotz O, etal., Graefes Arch Clin Exp Ophthalmol. 2000 Jan;238(1):88-93.
18.
Radiolabeled RGD uptake and alphav integrin expression is enhanced in ischemic murine hindlimbs.
Lee KH, etal., J Nucl Med. 2005 Mar;46(3):472-8.
19.
Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression.
Leong-Poi H, etal., Circulation. 2005 Jun 21;111(24):3248-54. Epub 2005 Jun 13.
20.
In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling.
Miller PG, etal., Cancer Cell. 2013 Jul 8;24(1):45-58. doi: 10.1016/j.ccr.2013.05.004. Epub 2013 Jun 13.
21.
alpha(V)beta (3) Integrin ligands enhance volume-sensitive calcium influx in mechanically stretched osteocytes.
Miyauchi A, etal., J Bone Miner Metab. 2006;24(6):498-504.
22.
Anti-alphav integrin monoclonal antibody intetumumab enhances the efficacy of radiation therapy and reduces metastasis of human cancer xenografts in nude rats.
Ning S, etal., Cancer Res. 2010 Oct 1;70(19):7591-9. doi: 10.1158/0008-5472.CAN-10-1639. Epub 2010 Sep 14.
23.
PID Annotation Import Pipeline
Pipeline to import Pathway Interaction Database annotations from NCI into RGD
24.
GOA pipeline
RGD automated data pipeline
25.
ClinVar Automated Import and Annotation Pipeline
RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
26.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
27.
Losartan prevents stretch-induced electrical remodeling in cultured atrial neonatal myocytes.
Saygili E, etal., Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2898-905. Epub 2007 Feb 9.
28.
The integrins.
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29.
Role of vitronectin receptor-type integrins and osteopontin in ischemia-induced retinal neovascularization.
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30.
Calcium-sensing receptor modulates cell adhesion and migration via integrins.
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Inhibitory effects of tranilast on expression of transforming growth factor-beta isoforms and receptors in injured arteries.
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SB-267268, a nonpeptidic antagonist of alpha(v)beta3 and alpha(v)beta5 integrins, reduces angiogenesis and VEGF expression in a mouse model of retinopathy of prematurity.
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Myocardial ischemic injury after heart transplantation is associated with upregulation of vitronectin receptor (alpha(v)beta3), activation of the matrix metalloproteinase induction system, and subsequent development of coronary vasculopathy.
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34.
Systemic activation of integrin alphaVbeta3 in donors with spontaneous intracerebral hemorrhage is associated with subsequent development of vasculopathy in the heart transplant recipient.
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35.
Inhibition of experimental choroidal neovascularization in rats by an alpha(v)-integrin antagonist.
Yasukawa T, etal., Curr Eye Res. 2004 May;28(5):359-66.
Itgav (Rattus norvegicus - Norway rat)
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 3 89,245,382 - 89,333,512 (+) NCBI GRCr8 mRatBN7.2 3 68,838,514 - 68,926,653 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 3 68,838,189 - 68,926,639 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 3 72,233,903 - 72,315,469 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 3 80,832,555 - 80,914,128 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 3 78,567,077 - 78,655,183 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 3 71,113,269 - 71,205,958 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 3 71,114,100 - 71,202,411 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 3 77,643,270 - 77,731,358 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 3 66,953,403 - 67,029,774 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 3 66,848,789 - 66,926,146 (+) NCBI Celera 3 68,209,136 - 68,297,332 (+) NCBI Celera Cytogenetic Map 3 q24 NCBI
ITGAV (Homo sapiens - human)
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 2 186,590,056 - 186,680,901 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 2 186,590,010 - 186,680,901 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 2 187,454,783 - 187,545,628 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 2 187,163,045 - 187,253,873 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 2 187,280,305 - 187,371,133 NCBI Celera 2 181,050,405 - 181,141,257 (+) NCBI Celera Cytogenetic Map 2 q32.1 NCBI HuRef 2 179,314,524 - 179,405,486 (+) NCBI HuRef CHM1_1 2 187,460,842 - 187,551,625 (+) NCBI CHM1_1 T2T-CHM13v2.0 2 187,079,132 - 187,170,024 (+) NCBI T2T-CHM13v2.0
Itgav (Mus musculus - house mouse)
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 2 83,554,796 - 83,637,261 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 2 83,554,741 - 83,637,260 (+) Ensembl GRCm39 Ensembl GRCm38 2 83,722,303 - 83,806,917 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 2 83,724,397 - 83,806,916 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 2 83,564,554 - 83,647,073 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 2 83,525,354 - 83,604,646 (+) NCBI MGSCv36 mm8 Celera 2 85,367,604 - 85,456,006 (+) NCBI Celera Cytogenetic Map 2 D NCBI cM Map 2 49.33 NCBI
Itgav (Chinchilla lanigera - long-tailed chinchilla)
Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955403 11,592,339 - 11,659,297 (-) Ensembl ChiLan1.0 ChiLan1.0 NW_004955403 11,588,536 - 11,669,809 (-) NCBI ChiLan1.0 ChiLan1.0
ITGAV (Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 13 89,252,238 - 89,359,439 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 2B 89,280,655 - 89,374,419 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 2B 73,880,962 - 73,972,486 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 2B 191,680,655 - 191,773,028 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 2B 191,680,655 - 191,773,028 (+) Ensembl panpan1.1 panPan2
ITGAV (Canis lupus familiaris - dog)
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 36 28,815,215 - 28,890,569 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 36 28,804,013 - 28,887,430 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 36 28,702,231 - 28,789,503 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 36 29,028,662 - 29,116,151 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 36 29,031,003 - 29,116,148 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 36 29,087,085 - 29,173,016 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 36 29,020,979 - 29,108,231 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 36 29,188,373 - 29,276,043 (+) NCBI UU_Cfam_GSD_1.0
Itgav (Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024405303 145,999,260 - 146,087,955 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936506 10,750,101 - 10,839,303 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936506 10,750,116 - 10,839,018 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
ITGAV (Sus scrofa - pig)
Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 15 91,604,676 - 91,711,851 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 15 91,604,666 - 91,711,843 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 15 101,654,958 - 101,717,935 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
ITGAV (Chlorocebus sabaeus - green monkey)
Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 10 72,125,710 - 72,216,757 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 10 72,125,962 - 72,216,809 (+) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666040 127,289,910 - 127,381,992 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Itgav (Heterocephalus glaber - naked mole-rat)
.
Predicted Target Of
Count of predictions: 44 Count of miRNA genes: 43 Interacting mature miRNAs: 44 Transcripts: ENSRNOT00000006961 Prediction methods: Miranda, Rnahybrid Result types: miRGate_prediction
1582238 Bw68 Body weight QTL 68 3.2 0.0064 body mass (VT:0001259) body weight (CMO:0000012) 3 53184593 115665732 Rat 1582239 Epfw1 Epididymal fat weight QTL 1 4.5 0.0006 epididymal fat pad mass (VT:0010421) epididymal fat pad weight to body weight ratio (CMO:0000658) 3 53184593 115665732 Rat 2298542 Neuinf11 Neuroinflammation QTL 11 3.9 nervous system integrity trait (VT:0010566) spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126) 3 15005422 76927699 Rat 1358362 Srcrt2 Stress Responsive Cort QTL 2 2.78 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 38192233 133483320 Rat 737818 Hcar12 Hepatocarcinoma resistance QTL 12 2.6 liver integrity trait (VT:0010547) volume of individual liver tumorous lesion (CMO:0001078) 3 29463235 118376539 Rat 1582218 Bw74 Body weight QTL 74 3.9 0.0021 body mass (VT:0001259) body weight (CMO:0000012) 3 53184593 115665732 Rat 1582221 Kidm30 Kidney mass QTL 30 3.5 0.0008 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 3 64655305 115665732 Rat 1581568 Rf53 Renal function QTL 53 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 3 56395968 161299569 Rat 1582210 Bw71 Body weight QTL 71 3.3 0.0012 body mass (VT:0001259) body weight (CMO:0000012) 3 64655305 115665732 Rat 1300111 Rf12 Renal function QTL 12 3.78 renal blood flow trait (VT:2000006) absolute change in renal blood flow rate (CMO:0001168) 3 61017749 121056321 Rat 9590286 Uminl1 Urine mineral level QTL 1 3.5 0.001 urine mineral amount (VT:0015086) urine electrolyte level (CMO:0000593) 3 28249687 73249687 Rat 724523 Tsu1 Thymus enlargement suppressive QTL 1 3.84 thymus mass (VT:0004954) thymus weight to body weight ratio (CMO:0000612) 3 50437504 115638231 Rat 8662816 Vetf4 Vascular elastic tissue fragility QTL 4 4 renal artery integrity trait (VT:0010642) number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563) 3 59242096 157323038 Rat 1581503 Cm58 Cardiac mass QTL 58 2.7 0.05 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 43827364 121056321 Rat 731180 Bp152 Blood pressure QTL 152 0.03 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 53781112 91609953 Rat 2292613 Ept16 Estrogen-induced pituitary tumorigenesis QTL 16 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 47233430 110362260 Rat 631200 Cm25 Cardiac mass QTL 25 4.8 0.0001 heart left ventricle mass (VT:0007031) heart left ventricle wet weight (CMO:0000071) 3 61134348 89115068 Rat 61356 Bp37 Blood pressure QTL 37 3 blood pressure trait (VT:0000183) systolic blood pressure (CMO:0000004) 3 30684642 75684642 Rat 1358905 Hrtrt17 Heart rate QTL 17 5.9 0.000014 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 10861912 89878372 Rat 2301971 Cm71 Cardiac mass QTL 71 4.63 heart left ventricle mass (VT:0007031) heart left ventricle weight (CMO:0000776) 3 41874578 155617519 Rat 8694196 Abfw2 Abdominal fat weight QTL 2 16.58 0.001 visceral adipose mass (VT:0010063) abdominal fat pad weight to body weight ratio (CMO:0000095) 3 28249687 73249687 Rat 2301970 Bw81 Body weight QTL 81 5.19 body mass (VT:0001259) body weight (CMO:0000012) 3 41874578 155617519 Rat 1358885 Bp251 Blood pressure QTL 251 3.8 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 2290452 Scl56 Serum cholesterol level QTL 56 2.26 blood cholesterol amount (VT:0000180) plasma total cholesterol level (CMO:0000585) 3 1 91609953 Rat 12879868 Am6 Aortic mass QTL 6 0.001 aorta mass (VT:0002845) aorta weight to aorta length to body weight ratio (CMO:0002722) 3 31426403 70668733 Rat 11565451 Bw177 Body weight QTL 177 0.002 body mass (VT:0001259) body weight (CMO:0000012) 3 31426403 70668733 Rat 1358888 Bp264 Blood pressure QTL 264 4.43 arterial blood pressure trait (VT:2000000) mean arterial blood pressure (CMO:0000009) 3 14489145 121056321 Rat 11565452 Kidm57 Kidney mass QTL 57 0.001 kidney mass (VT:0002707) both kidneys wet weight to body weight ratio (CMO:0000340) 3 31426403 70668733 Rat 12879866 Cm94 Cardiac mass QTL 94 0.001 heart left ventricle mass (VT:0007031) heart left ventricle weight to body weight ratio (CMO:0000530) 3 31426403 70668733 Rat 12879867 Cm95 Cardiac mass QTL 95 0.047 heart right ventricle mass (VT:0007033) heart right ventricle weight to body weight ratio (CMO:0000914) 3 31426403 70668733 Rat 1300178 Hrtrt4 Heart rate QTL 4 3.74 heart pumping trait (VT:2000009) heart rate (CMO:0000002) 3 43827364 90905114 Rat 61377 Edpm3 Estrogen-dependent pituitary mass QTL 3 7.05 0.038 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 53184692 89878207 Rat 2302055 Pia30 Pristane induced arthritis QTL 30 3.5 0.001 blood autoantibody amount (VT:0003725) serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111) 3 27936919 72936919 Rat 1331795 Rf30 Renal function QTL 30 3.708 urine potassium amount (VT:0010539) urine potassium level (CMO:0000128) 3 39454637 89115240 Rat 70216 Cm14 Cardiac mass QTL 14 2.1 heart mass (VT:0007028) heart wet weight (CMO:0000069) 3 31172320 163586636 Rat 1354589 Bw31 Body weight QTL 31 3.3 body mass (VT:0001259) body weight (CMO:0000012) 3 33703347 78196190 Rat 2303593 Gluco46 Glucose level QTL 46 3 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 3 28468571 73468571 Rat 1354590 Despr11 Despair related QTL 11 0.000031 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 3 28468571 73468571 Rat 2292591 Esta4 Estrogen-induced thymic atrophy QTL 4 thymus mass (VT:0004954) thymus wet weight (CMO:0000855) 3 47233211 147415807 Rat 1331777 Bw24 Body weight QTL 24 3.503 body mass (VT:0001259) body weight (CMO:0000012) 3 39454637 89115240 Rat 631647 Bp122 Blood pressure QTL 122 6.2 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 3 30684642 75684642 Rat 1559282 Emca5 Estrogen-induced mammary cancer QTL 5 3.9 mammary gland integrity trait (VT:0010552) percentage of study population developing mammary tumors during a period of time (CMO:0000948) 3 43827364 169034231 Rat 738019 Anxrr10 Anxiety related response QTL 10 3.9 exploratory behavior trait (VT:0010471) number of entries into a discrete space in an experimental apparatus (CMO:0000960) 3 38517803 83517803 Rat 9590136 Scort3 Serum corticosterone level QTL 3 23.37 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 3 28249687 73249687 Rat 61419 Cia11 Collagen induced arthritis QTL 11 5.6 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 3 30356773 98535386 Rat 1354597 Kidm13 Kidney mass QTL 13 2.9 kidney mass (VT:0002707) right kidney wet weight (CMO:0000082) 3 41874578 104104347 Rat 8552950 Pigfal12 Plasma insulin-like growth factor 1 level QTL 12 7.3 blood insulin-like growth factor amount (VT:0010479) plasma insulin-like growth factor 1 level (CMO:0001299) 3 28249687 73249687 Rat 8694386 Bw159 Body weight QTL 159 4.52 0.001 body lean mass (VT:0010483) lean tissue morphological measurement (CMO:0002184) 3 28249687 73249687 Rat 631665 Bw8 Body weight QTL 8 5.5 body mass (VT:0001259) body weight (CMO:0000012) 3 50437042 119183768 Rat 1354604 Bw36 Body weight QTL 36 2.9 body mass (VT:0001259) body weight (CMO:0000012) 3 33703347 104104347 Rat 2301400 Cm68 Cardiac mass QTL 68 0.001 heart mass (VT:0007028) heart wet weight to body weight ratio (CMO:0002408) 3 31426403 70668733 Rat 1358186 Ept2 Estrogen-induced pituitary tumorigenesis QTL 2 8.3 pituitary gland mass (VT:0010496) pituitary gland wet weight (CMO:0000853) 3 47233430 110362260 Rat
D3Got143
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 3 89,288,529 - 89,288,731 (+) Marker Load Pipeline mRatBN7.2 3 68,881,666 - 68,881,868 (+) MAPPER mRatBN7.2 Rnor_6.0 3 71,156,983 - 71,157,184 NCBI Rnor6.0 Rnor_5.0 3 77,686,821 - 77,687,022 UniSTS Rnor5.0 RGSC_v3.4 3 66,985,224 - 66,985,426 RGD RGSC3.4 RGSC_v3.4 3 66,985,225 - 66,985,426 UniSTS RGSC3.4 RGSC_v3.1 3 66,881,596 - 66,881,798 RGD Celera 3 68,252,850 - 68,253,051 UniSTS RH 2.0 Map 3 1034.3 RGD Cytogenetic Map 3 q24 UniSTS
RH140315
Rat Assembly Chr Position (strand) Source JBrowse mRatBN7.2 3 68,923,665 - 68,923,861 (+) MAPPER mRatBN7.2 Rnor_6.0 3 71,202,971 - 71,203,166 NCBI Rnor6.0 Rnor_5.0 3 77,728,371 - 77,728,566 UniSTS Rnor5.0 RGSC_v3.4 3 67,029,877 - 67,030,072 UniSTS RGSC3.4 Celera 3 68,294,341 - 68,294,536 UniSTS Cytogenetic Map 3 q24 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000006961 ⟹ ENSRNOP00000006961
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 68,838,189 - 68,926,639 (+) Ensembl Rnor_6.0 Ensembl 3 71,114,100 - 71,202,411 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000088549 ⟹ ENSRNOP00000069681
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 3 68,838,599 - 68,926,639 (+) Ensembl Rnor_6.0 Ensembl 3 71,114,100 - 71,202,411 (+) Ensembl
RefSeq Acc Id:
NM_001398692 ⟹ NP_001385621
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,245,382 - 89,333,512 (+) NCBI mRatBN7.2 3 68,838,514 - 68,926,653 (+) NCBI
RefSeq Acc Id:
NM_001398693 ⟹ NP_001385622
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,245,382 - 89,333,512 (+) NCBI mRatBN7.2 3 68,838,514 - 68,926,653 (+) NCBI
RefSeq Acc Id:
XM_039106447 ⟹ XP_038962375
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,266,090 - 89,333,512 (+) NCBI mRatBN7.2 3 68,859,226 - 68,926,653 (+) NCBI
RefSeq Acc Id:
XM_063283421 ⟹ XP_063139491
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,248,393 - 89,333,512 (+) NCBI
RefSeq Acc Id:
XR_010064598
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,245,526 - 89,333,512 (+) NCBI
RefSeq Acc Id:
XR_010064599
Type:
NON-CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 3 89,245,504 - 89,333,512 (+) NCBI
Ensembl Acc Id:
ENSRNOP00000006961 ⟸ ENSRNOT00000006961
Ensembl Acc Id:
ENSRNOP00000069681 ⟸ ENSRNOT00000088549
RefSeq Acc Id:
XP_038962375 ⟸ XM_039106447
- Peptide Label:
isoform X2
RefSeq Acc Id:
NP_001385621 ⟸ NM_001398692
- Peptide Label:
isoform 1 precursor
- UniProtKB:
A0A0G2JVZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id:
NP_001385622 ⟸ NM_001398693
- Peptide Label:
isoform 2 precursor
- UniProtKB:
F1LZX9 (UniProtKB/TrEMBL), A0A0G2JVZ6 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063139491 ⟸ XM_063283421
- Peptide Label:
isoform X1
- UniProtKB:
A0A0G2JVZ6 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2015-12-23
Itgav
integrin subunit alpha V
Itgav
integrin, alpha V
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2009-12-15
Itgav
integrin, alpha V
Itgav
integrin alpha V
Nomenclature updated to reflect human and mouse nomenclature
1299863
APPROVED
2008-04-30
Itgav
integrin alpha V
Itgav_predicted
integrin alpha V (predicted)
'predicted' is removed
2292626
APPROVED
2006-03-30
Itgav_predicted
integrin alpha V (predicted)
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (predicted)
Name updated
1299863
APPROVED
2005-01-12
Itgav_predicted
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) (predicted)
Symbol and Name status set to approved
70820
APPROVED