Mapk11 (mitogen-activated protein kinase 11) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mapk11 (mitogen-activated protein kinase 11) Rattus norvegicus
Analyze
Symbol: Mapk11
Name: mitogen-activated protein kinase 11
RGD ID: 1309340
Description: Enables ATP binding activity and MAP kinase activity. Predicted to be involved in several processes, including MAPK cascade; cellular response to UV-B; and positive regulation of interleukin-12 production. Predicted to act upstream of or within several processes, including NLRP1 inflammasome complex assembly; negative regulation of cardiac muscle cell proliferation; and pyroptotic inflammatory response. Predicted to be active in cytosol and nucleus. Orthologous to human MAPK11 (mitogen-activated protein kinase 11); PARTICIPATES IN adenosine signaling pathway; eicosanoid signaling pathway; FasL mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362982; LOC689314; MGC187942; p38beta; similar to mitogen-activated protein kinase 11
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,098,120 - 122,105,023 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,098,121 - 122,105,038 (-)EnsemblGRCr8
mRatBN7.27120,218,471 - 120,225,488 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,970,470 - 121,976,406 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,196,633 - 124,202,569 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,159,641 - 124,165,578 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,121,678 - 130,129,199 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)Ensemblrn6Rnor6.0
Rnor_5.07129,808,443 - 129,814,378 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,444,055 - 127,449,990 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,693,340 - 116,699,275 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-nitrophenol  (ISO)
acrolein  (ISO)
acrylamide  (EXP,ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
berberine  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP)
disodium selenite  (ISO)
elemental selenium  (ISO)
ellagic acid  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
flurbiprofen  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
formononetin  (ISO)
genistein  (ISO)
GSK-J4  (ISO)
hemin  (ISO)
hexadecanoic acid  (EXP)
ibuprofen  (ISO)
lead diacetate  (EXP,ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-4-phenylpyridinium  (EXP)
nicotine  (ISO)
nilotinib  (ISO)
nitrates  (ISO)
Nonylphenol  (EXP)
Nutlin-3  (ISO)
obeticholic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
PCB138  (EXP)
pentanal  (ISO)
pyrazoles  (ISO)
pyrimidines  (ISO)
quercetin  (ISO)
reactive oxygen species  (EXP)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 203580  (EXP,ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
streptozocin  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
Urolithin A  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
xanthohumol  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
cytosol  (IEA,ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. p38 MAP-kinases pathway regulation, function and role in human diseases. Cuenda A and Rousseau S, Biochim Biophys Acta. 2007 Aug;1773(8):1358-75. Epub 2007 Mar 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Melatonin arrests peroxynitrite-induced tau hyperphosphorylation and the overactivation of protein kinases in rat brain. Yin J, etal., J Pineal Res. 2006 Sep;41(2):124-9.
Additional References at PubMed
PMID:8663524   PMID:10330143   PMID:12477932   PMID:16364914   PMID:17069850   PMID:18515110   PMID:20134354   PMID:21354263   PMID:21768366   PMID:21777656   PMID:22157753   PMID:23483889  
PMID:24465521   PMID:25754930   PMID:34814904  


Genomics

Comparative Map Data
Mapk11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87122,098,120 - 122,105,023 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl7122,098,121 - 122,105,038 (-)EnsemblGRCr8
mRatBN7.27120,218,471 - 120,225,488 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx7121,970,470 - 121,976,406 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07124,196,633 - 124,202,569 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07124,159,641 - 124,165,578 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.07130,121,678 - 130,129,199 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)Ensemblrn6Rnor6.0
Rnor_5.07129,808,443 - 129,814,378 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.47127,444,055 - 127,449,990 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7116,693,340 - 116,699,275 (-)NCBICelera
Cytogenetic Map7q34NCBI
MAPK11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382250,263,713 - 50,270,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2250,263,713 - 50,270,767 (-)Ensemblhg38GRCh38
GRCh372250,702,142 - 50,708,809 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,044,269 - 49,050,906 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342249,004,599 - 49,011,236NCBI
Celera2234,577,045 - 34,583,684 (-)NCBICelera
Cytogenetic Map22q13.33NCBI
HuRef2233,599,558 - 33,605,992 (-)NCBIHuRef
CHM1_12250,660,928 - 50,667,565 (-)NCBICHM1_1
T2T-CHM13v2.02250,770,716 - 50,777,383 (-)NCBIT2T-CHM13v2.0
Mapk11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391589,026,685 - 89,033,809 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1589,026,689 - 89,033,831 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381589,142,482 - 89,149,606 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1589,142,486 - 89,149,628 (-)Ensemblmm10GRCm38
MGSCv371588,972,912 - 88,980,036 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361588,970,248 - 88,977,323 (-)NCBIMGSCv36mm8
Celera1591,271,050 - 91,278,706 (-)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1544.66NCBI
Mapk11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541333,286,390 - 33,294,227 (-)Ensembl
ChiLan1.0NW_00495541333,287,860 - 33,293,948 (-)NCBIChiLan1.0ChiLan1.0
MAPK11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22360,169,844 - 60,176,642 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12262,856,001 - 62,862,799 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02230,492,664 - 30,499,456 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12249,491,462 - 49,495,766 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2249,492,693 - 49,495,732 (-)EnsemblpanPan2panpan1.1
MAPK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11016,977,133 - 16,984,764 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1016,955,828 - 16,963,117 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01017,704,608 - 17,711,910 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1017,705,414 - 17,711,909 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11017,428,715 - 17,435,996 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01017,752,004 - 17,759,275 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01017,884,182 - 17,891,467 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Mapk11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945545,727 - 549,861 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936629545,755 - 549,837 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936629542,143 - 549,861 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl5421,798 - 428,101 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.15420,848 - 428,103 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
MAPK11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11932,754,261 - 32,760,859 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1932,752,546 - 32,760,798 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604592,593,845 - 92,600,476 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mapk11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624752502,350 - 508,449 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624752502,411 - 508,452 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Mapk11
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11258,445,695 - 258,452,691 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Mapk11
37 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:198
Count of miRNA genes:129
Interacting mature miRNAs:161
Transcripts:ENSRNOT00000009325
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354582Stl11Serum triglyceride level QTL 113.42blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7121393075137014596Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7119280025135560836Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)782111245123048330Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7104186212135371468Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)793302009131686183Rat
61397Bw17Body weight QTL 176.3body mass (VT:0001259)body weight (CMO:0000012)795485047137014596Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7115313999136544683Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)785043242130043242Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)785497398130497398Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)792362341137014596Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)783626689128626689Rat
631529Tls2T-lymphoma susceptibility QTL 200.001thymus integrity trait (VT:0010555)percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)782111382132099989Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)798549867137014596Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)782111245123048330Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7110725024135371468Rat
61428Scl3Serum cholesterol level QTL 33.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)7100548246137014596Rat
1331746Kidm9Kidney mass QTL 93.934kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)782111245134948181Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)777807807122807807Rat
1582240Sffal1Serum free fatty acids level QTL 13.40.0021blood free fatty acid amount (VT:0001553)serum free fatty acids level (CMO:0000547)7118556868125929417Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)7116269196132020414Rat
10402855Bp379Blood pressure QTL 3790.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)778682549123682549Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)771827901136544683Rat

Markers in Region
RH137764  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,218,528 - 120,218,715 (+)MAPPERmRatBN7.2
Rnor_6.07130,121,738 - 130,121,924NCBIRnor6.0
Rnor_5.07129,807,527 - 129,807,713UniSTSRnor5.0
RGSC_v3.47127,443,139 - 127,443,325UniSTSRGSC3.4
Celera7116,692,424 - 116,692,610UniSTS
RH 3.4 Map7958.3UniSTS
Cytogenetic Map7q34UniSTS
Mapk11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27120,218,618 - 120,219,676 (+)MAPPERmRatBN7.2
Rnor_6.07130,121,828 - 130,122,885NCBIRnor6.0
Rnor_5.07129,807,617 - 129,808,674UniSTSRnor5.0
RGSC_v3.47127,443,229 - 127,444,286UniSTSRGSC3.4
Celera7116,692,514 - 116,693,571UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 64 151 91 90 59 81 59 6 335 178 11 130 74 92 31 15 15

Sequence


Ensembl Acc Id: ENSRNOT00000009325   ⟹   ENSRNOP00000009325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,098,121 - 122,105,038 (-)Ensembl
mRatBN7.2 Ensembl7120,218,478 - 120,225,395 (-)Ensembl
Rnor_6.0 Ensembl7130,121,687 - 130,128,604 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079777   ⟹   ENSRNOP00000075602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl7122,099,088 - 122,105,023 (-)Ensembl
mRatBN7.2 Ensembl7120,219,445 - 120,225,380 (-)Ensembl
Rnor_6.0 Ensembl7130,122,654 - 130,128,589 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104992   ⟹   ENSRNOP00000080828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7120,218,478 - 120,225,309 (-)Ensembl
RefSeq Acc Id: NM_001109532   ⟹   NP_001103002
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,099,088 - 122,105,023 (-)NCBI
mRatBN7.27120,219,445 - 120,225,380 (-)NCBI
Rnor_6.07130,122,654 - 130,128,589 (-)NCBI
Rnor_5.07129,808,443 - 129,814,378 (-)NCBI
RGSC_v3.47127,444,055 - 127,449,990 (-)RGD
Celera7116,693,340 - 116,699,275 (-)RGD
Sequence:
RefSeq Acc Id: XM_017595119   ⟹   XP_017450608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,098,120 - 122,104,969 (-)NCBI
mRatBN7.27120,218,471 - 120,225,475 (-)NCBI
Rnor_6.07130,121,678 - 130,128,641 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079918   ⟹   XP_038935846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,100,605 - 122,104,969 (-)NCBI
mRatBN7.27120,220,962 - 120,225,487 (-)NCBI
RefSeq Acc Id: XM_039079919   ⟹   XP_038935847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,100,877 - 122,104,969 (-)NCBI
mRatBN7.27120,221,234 - 120,225,488 (-)NCBI
RefSeq Acc Id: XM_063264275   ⟹   XP_063120345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87122,098,120 - 122,103,781 (-)NCBI
RefSeq Acc Id: NP_001103002   ⟸   NM_001109532
- UniProtKB: A0A0G2KB06 (UniProtKB/TrEMBL),   A0A8I6G769 (UniProtKB/TrEMBL),   A6K7K4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450608   ⟸   XM_017595119
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G769 (UniProtKB/TrEMBL),   B1WC76 (UniProtKB/TrEMBL),   D4A3U7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075602   ⟸   ENSRNOT00000079777
Ensembl Acc Id: ENSRNOP00000009325   ⟸   ENSRNOT00000009325
RefSeq Acc Id: XP_038935846   ⟸   XM_039079918
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038935847   ⟸   XM_039079919
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000080828   ⟸   ENSRNOT00000104992
RefSeq Acc Id: XP_063120345   ⟸   XM_063264275
- Peptide Label: isoform X2
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3U7-F1-model_v2 AlphaFold D4A3U7 1-371 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309340 AgrOrtholog
BioCyc Gene G2FUF-32460 BioCyc
Ensembl Genes ENSRNOG00000006984 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009325 ENTREZGENE
  ENSRNOT00000009325.8 UniProtKB/TrEMBL
  ENSRNOT00000079777 ENTREZGENE
  ENSRNOT00000079777.3 UniProtKB/TrEMBL
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  MAP_kinase UniProtKB/TrEMBL
  MAP_kinase_CS UniProtKB/TrEMBL
  MAPK_p38 UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
KEGG Report rno:689314 UniProtKB/TrEMBL
NCBI Gene Mapk11 ENTREZGENE
PANTHER MITOGEN-ACTIVATED PROTEIN KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Mapk11 PhenoGen
PRINTS P38MAPKINASE UniProtKB/TrEMBL
PROSITE MAPK UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000006984 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A0G2KB06 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G769 ENTREZGENE
  A6K7K4 ENTREZGENE, UniProtKB/TrEMBL
  B1WC76 ENTREZGENE
  D4A3U7 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B1WC76 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-22 Mapk11  mitogen-activated protein kinase 11   LOC689314  similar to mitogen-activated protein kinase 11  Data merged from RGD:1593550 737654 APPROVED
2008-04-30 Mapk11  mitogen-activated protein kinase 11   Mapk11_predicted  mitogen-activated protein kinase 11 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC689314  similar to mitogen-activated protein kinase 11      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Mapk11_predicted  mitogen-activated protein kinase 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED