Eif4g1 (eukaryotic translation initiation factor 4 gamma 1) - Rat Genome Database

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Gene: Eif4g1 (eukaryotic translation initiation factor 4 gamma 1) Rattus norvegicus
Analyze
Symbol: Eif4g1
Name: eukaryotic translation initiation factor 4 gamma 1
RGD ID: 1306144
Description: Enables eukaryotic initiation factor 4E binding activity. Involved in lung development and response to ethanol. Part of eukaryotic translation initiation factor 4F complex. Is active in postsynapse. Human ortholog(s) of this gene implicated in late onset Parkinson's disease. Orthologous to human EIF4G1 (eukaryotic translation initiation factor 4 gamma 1); PARTICIPATES IN translation initiation pathway; myocarditis pathway; RNA transport pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eukaryotic translation initiation factor 4 gamma 1-like; LOC100912571; LOC102550847; LOC287986; voltage-dependent P/Q-type calcium channel subunit alpha-1A-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Eif4g1-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,726,322 - 93,746,387 (-)NCBIGRCr8
mRatBN7.21180,221,919 - 80,241,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,221,919 - 80,241,941 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01183,907,659 - 83,927,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,908,109 - 83,926,524 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01186,979,577 - 86,999,605 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,451,555 - 82,471,735 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,509,144 - 82,529,350 (-)NCBI
Celera1179,061,657 - 79,081,657 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
7-methyl-GTP  (ISO)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A5  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
captan  (ISO)
carbamazepine  (ISO)
chloroprene  (EXP)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
coumarin  (ISO)
curcumin  (ISO)
cycloheximide  (EXP)
D-glucose  (ISO)
decabromodiphenyl ether  (EXP,ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (EXP)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
everolimus  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glafenine  (EXP)
glucose  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
lycopene  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
nefazodone  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
Nutlin-3  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pyrogallol  (ISO)
resveratrol  (ISO)
SB 203580  (ISO)
selenium atom  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (EXP)
tebufenpyrad  (ISO)
testosterone enanthate  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
torcetrapib  (ISO)
torin 1  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Inhibition of Cap-initiation complexes linked to a novel mechanism of eIF4G depletion in acute myocardial ischemia. Connolly EP, etal., Cell Death Differ. 2006 Sep;13(9):1586-94. Epub 2006 Jan 27.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. Global and gene-specific translational regulation in rat lung development. Otulakowski G, etal., Am J Respir Cell Mol Biol. 2009 May;40(5):555-67. Epub 2008 Oct 23.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Acute alcohol intoxication enhances myocardial eIF4G phosphorylation despite reducing mTOR signaling. Vary TC, etal., Am J Physiol Heart Circ Physiol. 2005 Jan;288(1):H121-8. Epub 2004 Sep 23.
10. Dendritic BC1 RNA: functional role in regulation of translation initiation. Wang H, etal., J Neurosci 2002 Dec 1;22(23):10232-41.
Additional References at PubMed
PMID:12388085   PMID:12477932   PMID:16306159   PMID:16698552   PMID:17117141   PMID:17556672   PMID:18426977   PMID:19648179   PMID:19946888   PMID:21289279   PMID:22006312   PMID:22658674  
PMID:23106098   PMID:23409027   PMID:23814182   PMID:24092755   PMID:24990923   PMID:25255371   PMID:25456498   PMID:25468996   PMID:25533483   PMID:29062139  


Genomics

Comparative Map Data
Eif4g1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81193,726,322 - 93,746,387 (-)NCBIGRCr8
mRatBN7.21180,221,919 - 80,241,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1180,221,919 - 80,241,941 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01183,907,659 - 83,927,683 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1183,908,109 - 83,926,524 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01186,979,577 - 86,999,605 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41182,451,555 - 82,471,735 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11182,509,144 - 82,529,350 (-)NCBI
Celera1179,061,657 - 79,081,657 (-)NCBICelera
Cytogenetic Map11q23NCBI
EIF4G1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,314,606 - 184,335,358 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3184,314,495 - 184,335,358 (+)EnsemblGRCh38hg38GRCh38
GRCh373184,032,394 - 184,053,146 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363185,515,050 - 185,535,840 (+)NCBINCBI36Build 36hg18NCBI36
Celera3182,472,966 - 182,494,042 (+)NCBICelera
Cytogenetic Map3q27.1NCBI
HuRef3181,439,248 - 181,459,772 (+)NCBIHuRef
CHM1_13183,996,741 - 184,017,602 (+)NCBICHM1_1
T2T-CHM13v2.03187,123,882 - 187,144,618 (+)NCBIT2T-CHM13v2.0
Eif4g1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391620,491,457 - 20,511,633 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1620,487,063 - 20,511,634 (+)EnsemblGRCm39 Ensembl
GRCm381620,672,720 - 20,692,883 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1620,668,313 - 20,692,884 (+)EnsemblGRCm38mm10GRCm38
MGSCv371620,672,822 - 20,692,956 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361620,586,292 - 20,606,426 (+)NCBIMGSCv36mm8
Celera1621,237,424 - 21,258,239 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1612.49NCBI
Eif4g1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542023,161,078 - 23,180,568 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542023,161,541 - 23,179,788 (-)NCBIChiLan1.0ChiLan1.0
EIF4G1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22182,187,847 - 182,208,674 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13182,192,564 - 182,213,391 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03181,351,938 - 181,372,776 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13189,833,575 - 189,854,291 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3189,833,490 - 189,855,060 (+)Ensemblpanpan1.1panPan2
EIF4G1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13417,194,588 - 17,214,498 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3417,195,562 - 17,214,052 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3421,280,776 - 21,300,463 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03417,102,466 - 17,122,377 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,102,483 - 17,122,376 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13417,139,588 - 17,159,277 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03417,135,671 - 17,155,361 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03417,364,627 - 17,384,317 (+)NCBIUU_Cfam_GSD_1.0
Eif4g1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602119,456,677 - 119,475,343 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365785,548,500 - 5,567,339 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365785,548,526 - 5,567,220 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF4G1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13122,203,508 - 122,225,360 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113122,203,488 - 122,225,371 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213131,643,301 - 131,665,146 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF4G1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1155,085,326 - 5,106,551 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl155,084,780 - 5,105,288 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606313,862,963 - 13,884,237 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif4g1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473072,251,840 - 72,271,724 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eif4g1
48 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:266
Count of miRNA genes:111
Interacting mature miRNAs:118
Transcripts:ENSRNOT00000040029, ENSRNOT00000041777
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat

Markers in Region
RH138917  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01173,813,398 - 73,813,536NCBIRnor5.0
Rnor_5.01186,984,353 - 86,984,491NCBIRnor5.0
Rnor_5.01185,970,297 - 85,970,435NCBIRnor5.0
RGSC_v3.41182,456,333 - 82,456,470UniSTSRGSC3.4
RGSC_v3.41169,316,683 - 69,316,820UniSTSRGSC3.4
Celera1179,066,434 - 79,066,571UniSTS
Celera1166,942,233 - 66,942,370UniSTS
RH 3.4 Map20490.34UniSTS
Cytogenetic Map11q22UniSTS
Cytogenetic Map11q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006221195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008758195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017604365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063270360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000040029   ⟹   ENSRNOP00000040698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,221,919 - 80,241,303 (-)Ensembl
Rnor_6.0 Ensembl1183,908,109 - 83,926,524 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000041777   ⟹   ENSRNOP00000049629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,221,919 - 80,241,941 (-)Ensembl
Rnor_6.0 Ensembl1183,908,109 - 83,926,524 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075306   ⟹   ENSRNOP00000067492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1180,221,919 - 80,241,303 (-)Ensembl
Rnor_6.0 Ensembl1182,886,878 - 82,893,845 (-)Ensembl
RefSeq Acc Id: NM_001427476   ⟹   NP_001414405
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,367 (-)NCBI
RefSeq Acc Id: XM_006248581   ⟹   XP_006248643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,368 (-)NCBI
mRatBN7.21180,221,919 - 80,241,956 (-)NCBI
Rnor_6.01183,907,659 - 83,927,674 (-)NCBI
Rnor_5.01186,979,577 - 86,999,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248584   ⟹   XP_006248646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
mRatBN7.21180,221,919 - 80,241,958 (-)NCBI
Rnor_6.01183,907,659 - 83,927,683 (-)NCBI
Rnor_5.01186,979,577 - 86,999,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006248585   ⟹   XP_006248647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,368 (-)NCBI
mRatBN7.21180,221,919 - 80,241,956 (-)NCBI
Rnor_6.01183,907,659 - 83,927,674 (-)NCBI
Rnor_5.01186,979,577 - 86,999,605 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598182   ⟹   XP_017453671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,365 (-)NCBI
mRatBN7.21180,221,919 - 80,241,958 (-)NCBI
Rnor_6.01183,907,659 - 83,927,674 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598183   ⟹   XP_017453672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
mRatBN7.21180,221,919 - 80,241,500 (-)NCBI
Rnor_6.01183,907,659 - 83,927,235 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063270336   ⟹   XP_063126406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270337   ⟹   XP_063126407
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270338   ⟹   XP_063126408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270339   ⟹   XP_063126409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,365 (-)NCBI
RefSeq Acc Id: XM_063270340   ⟹   XP_063126410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,368 (-)NCBI
RefSeq Acc Id: XM_063270341   ⟹   XP_063126411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,365 (-)NCBI
RefSeq Acc Id: XM_063270342   ⟹   XP_063126412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270343   ⟹   XP_063126413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270344   ⟹   XP_063126414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,369 (-)NCBI
RefSeq Acc Id: XM_063270345   ⟹   XP_063126415
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270346   ⟹   XP_063126416
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270347   ⟹   XP_063126417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,369 (-)NCBI
RefSeq Acc Id: XM_063270348   ⟹   XP_063126418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270349   ⟹   XP_063126419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,745,952 (-)NCBI
RefSeq Acc Id: XM_063270350   ⟹   XP_063126420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270351   ⟹   XP_063126421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,368 (-)NCBI
RefSeq Acc Id: XM_063270352   ⟹   XP_063126422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270353   ⟹   XP_063126423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,387 (-)NCBI
RefSeq Acc Id: XM_063270354   ⟹   XP_063126424
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,368 (-)NCBI
RefSeq Acc Id: XM_063270355   ⟹   XP_063126425
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,746,369 (-)NCBI
RefSeq Acc Id: XM_063270356   ⟹   XP_063126426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,740,482 (-)NCBI
RefSeq Acc Id: XM_063270357   ⟹   XP_063126427
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,740,453 (-)NCBI
RefSeq Acc Id: XM_063270358   ⟹   XP_063126428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,740,696 (-)NCBI
RefSeq Acc Id: XM_063270360   ⟹   XP_063126430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81193,726,322 - 93,740,694 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414405 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248643 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248646 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248647 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453671 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453672 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126406 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126407 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126408 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126409 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126410 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126411 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126412 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126413 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126414 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126415 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126416 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126417 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126418 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126419 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126420 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126421 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126422 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126423 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126424 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126425 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126426 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126427 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126428 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126430 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040698.5
  ENSRNOP00000049629.3
  ENSRNOP00000067492.2
RefSeq Acc Id: XP_006248646   ⟸   XM_006248584
- Peptide Label: isoform X5
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248647   ⟸   XM_006248585
- Peptide Label: isoform X5
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006248643   ⟸   XM_006248581
- Peptide Label: isoform X1
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453671   ⟸   XM_017598182
- Peptide Label: isoform X1
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453672   ⟸   XM_017598183
- Peptide Label: isoform X1
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000049629   ⟸   ENSRNOT00000041777
Ensembl Acc Id: ENSRNOP00000040698   ⟸   ENSRNOT00000040029
Ensembl Acc Id: ENSRNOP00000067492   ⟸   ENSRNOT00000075306
RefSeq Acc Id: XP_063126423   ⟸   XM_063270353
- Peptide Label: isoform X14
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126422   ⟸   XM_063270352
- Peptide Label: isoform X13
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126420   ⟸   XM_063270350
- Peptide Label: isoform X12
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126418   ⟸   XM_063270348
- Peptide Label: isoform X11
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126416   ⟸   XM_063270346
- Peptide Label: isoform X10
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126413   ⟸   XM_063270343
- Peptide Label: isoform X8
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126425   ⟸   XM_063270355
- Peptide Label: isoform X15
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126417   ⟸   XM_063270347
- Peptide Label: isoform X10
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126414   ⟸   XM_063270344
- Peptide Label: isoform X8
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126424   ⟸   XM_063270354
- Peptide Label: isoform X14
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126421   ⟸   XM_063270351
- Peptide Label: isoform X13
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126410   ⟸   XM_063270340
- Peptide Label: isoform X6
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414405   ⟸   NM_001427476
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126411   ⟸   XM_063270341
- Peptide Label: isoform X6
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126409   ⟸   XM_063270339
- Peptide Label: isoform X5
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126419   ⟸   XM_063270349
- Peptide Label: isoform X11
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126415   ⟸   XM_063270345
- Peptide Label: isoform X9
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126412   ⟸   XM_063270342
- Peptide Label: isoform X7
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126408   ⟸   XM_063270338
- Peptide Label: isoform X4
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126406   ⟸   XM_063270336
- Peptide Label: isoform X2
- UniProtKB: D3ZU13 (UniProtKB/TrEMBL),   M0RD03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126407   ⟸   XM_063270337
- Peptide Label: isoform X3
- UniProtKB: M0RD03 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126428   ⟸   XM_063270358
- Peptide Label: isoform X18
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126430   ⟸   XM_063270360
- Peptide Label: isoform X19
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126426   ⟸   XM_063270356
- Peptide Label: isoform X16
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063126427   ⟸   XM_063270357
- Peptide Label: isoform X17
- UniProtKB: D4AD15 (UniProtKB/TrEMBL)
Protein Domains
MI   W2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RD03-F1-model_v2 AlphaFold M0RD03 1-530 view protein structure
AF-D3ZU13-F1-model_v2 AlphaFold D3ZU13 1-1598 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698271
Promoter ID:EPDNEW_R8796
Type:single initiation site
Name:Eif4g1_1
Description:eukaryotic translation initiation factor 4 gamma, 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01183,926,505 - 83,926,565EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306144 AgrOrtholog
BioCyc Gene G2FUF-20752 BioCyc
Ensembl Genes ENSRNOG00000001738 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000049598 Ensembl
Ensembl Transcript ENSRNOT00000040029.6 UniProtKB/TrEMBL
  ENSRNOT00000041777.7 UniProtKB/TrEMBL
  ENSRNOT00000075306.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.180 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7380777 IMAGE-MGC_LOAD
InterPro ARM-type_fold UniProtKB/TrEMBL
  eIF5C UniProtKB/TrEMBL
  IF4G UniProtKB/TrEMBL
  Initiation_fac_eIF4g_MI UniProtKB/TrEMBL
  MIF4G-like_typ-3 UniProtKB/TrEMBL
MGC_CLONE MGC:112933 IMAGE-MGC_LOAD
NCBI Gene 287986 ENTREZGENE
PANTHER PTHR23253 UniProtKB/TrEMBL
  PTHR23253:SF10 UniProtKB/TrEMBL
Pfam MA3 UniProtKB/TrEMBL
  MIF4G UniProtKB/TrEMBL
  PF02020 UniProtKB/TrEMBL
PhenoGen Eif4g1 PhenoGen
PROSITE PS51363 UniProtKB/TrEMBL
  PS51366 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001738 RatGTEx
  ENSRNOG00000049598 RatGTEx
SMART eIF5C UniProtKB/TrEMBL
  MA3 UniProtKB/TrEMBL
  MIF4G UniProtKB/TrEMBL
Superfamily-SCOP ARM-type_fold UniProtKB/TrEMBL
UniProt D3ZU13 ENTREZGENE, UniProtKB/TrEMBL
  D4AD15 ENTREZGENE, UniProtKB/TrEMBL
  M0RD03 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-04-14 Eif4g1  eukaryotic translation initiation factor 4 gamma 1  Eif4g1  eukaryotic translation initiation factor 4 gamma, 1  Name changed 629549 APPROVED
2021-03-09 Eif4g1  eukaryotic translation initiation factor 4 gamma, 1  LOC100912571  eukaryotic translation initiation factor 4 gamma 1-like  Data merged from RGD:6486329 737654 PROVISIONAL
2015-07-29 Eif4g1  eukaryotic translation initiation factor 4 gamma, 1  LOC102550847  voltage-dependent P/Q-type calcium channel subunit alpha-1A-like  Data merged from RGD:7628175 737654 PROVISIONAL
2013-12-18 LOC102550847  voltage-dependent P/Q-type calcium channel subunit alpha-1A-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100912571  eukaryotic translation initiation factor 4 gamma 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Eif4g1  eukaryotic translation initiation factor 4 gamma, 1  Eif4g1_predicted  eukaryotic translation initiation factor 4 gamma, 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Eif4g1_predicted  eukaryotic translation initiation factor 4 gamma, 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED