Mdga2 (MAM domain containing glycosylphosphatidylinositol anchor 2) - Rat Genome Database

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Gene: Mdga2 (MAM domain containing glycosylphosphatidylinositol anchor 2) Rattus norvegicus
Analyze
Symbol: Mdga2
Name: MAM domain containing glycosylphosphatidylinositol anchor 2
RGD ID: 735131
Description: Involved in regulation of synapse maturation and spinal cord motor neuron differentiation. Is active in glutamatergic synapse and postsynaptic density membrane. Orthologous to human MDGA2 (MAM domain containing glycosylphosphatidylinositol anchor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; allethrin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MAM domain-containing glycosylphosphatidylinositol anchor protein 2; MAM domain-containing protein 1; Mamdc1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8690,482,687 - 91,346,784 (-)NCBIGRCr8
mRatBN7.2684,746,422 - 85,608,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl684,761,941 - 85,608,126 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx685,123,229 - 85,979,390 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0685,422,600 - 86,278,801 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0684,864,059 - 85,717,130 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0688,442,620 - 89,292,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl688,447,749 - 88,917,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0697,916,163 - 98,773,394 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4688,155,407 - 89,020,699 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1688,158,867 - 89,024,155 (-)NCBI
Celera683,298,219 - 84,140,941 (-)NCBICelera
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization. Litwack ED, etal., Mol Cell Neurosci. 2004 Feb;25(2):263-74.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior. Toledo A, etal., Elife. 2022 May 9;11:e75233. doi: 10.7554/eLife.75233.
Additional References at PubMed
PMID:1633717   PMID:23248271   PMID:25162227   PMID:27608760  


Genomics

Comparative Map Data
Mdga2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8690,482,687 - 91,346,784 (-)NCBIGRCr8
mRatBN7.2684,746,422 - 85,608,640 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl684,761,941 - 85,608,126 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx685,123,229 - 85,979,390 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0685,422,600 - 86,278,801 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0684,864,059 - 85,717,130 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0688,442,620 - 89,292,454 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl688,447,749 - 88,917,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0697,916,163 - 98,773,394 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4688,155,407 - 89,020,699 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1688,158,867 - 89,024,155 (-)NCBI
Celera683,298,219 - 84,140,941 (-)NCBICelera
Cytogenetic Map6q24NCBI
MDGA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381446,839,623 - 47,675,605 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1446,840,092 - 47,675,605 (-)EnsemblGRCh38hg38GRCh38
GRCh371447,308,826 - 48,144,808 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361446,379,045 - 46,882,145 (-)NCBINCBI36Build 36hg18NCBI36
Build 341446,379,045 - 46,882,145NCBI
Celera1427,169,381 - 28,004,719 (-)NCBICelera
Cytogenetic Map14q21.3NCBI
HuRef1427,426,615 - 28,261,881 (-)NCBIHuRef
CHM1_11447,247,613 - 48,082,719 (-)NCBICHM1_1
T2T-CHM13v2.01441,038,514 - 41,874,449 (-)NCBIT2T-CHM13v2.0
Mdga2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391266,512,832 - 67,269,323 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1266,512,834 - 67,269,323 (-)EnsemblGRCm39 Ensembl
GRCm381266,459,419 - 67,222,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1266,466,060 - 67,222,549 (-)EnsemblGRCm38mm10GRCm38
MGSCv371267,572,169 - 68,322,190 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361267,389,787 - 68,139,808 (-)NCBIMGSCv36mm8
Celera1267,602,561 - 68,352,775 (-)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1227.63NCBI
Mdga2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540914,684,611 - 15,449,388 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540914,684,252 - 15,449,388 (+)NCBIChiLan1.0ChiLan1.0
MDGA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21547,971,234 - 48,818,509 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11447,187,743 - 48,036,253 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01427,434,904 - 28,274,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11445,752,214 - 46,584,148 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1445,752,214 - 46,583,991 (-)Ensemblpanpan1.1panPan2
MDGA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1823,827,284 - 24,608,003 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl823,832,475 - 24,607,866 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha823,644,302 - 23,948,023 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0823,992,881 - 24,785,403 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl823,999,793 - 24,785,345 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1823,651,714 - 24,434,692 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0823,720,107 - 24,501,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0824,049,174 - 24,831,369 (-)NCBIUU_Cfam_GSD_1.0
Mdga2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864055,878,524 - 56,640,257 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365832,048,733 - 2,804,135 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365832,048,655 - 2,804,135 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MDGA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1176,770,071 - 177,593,876 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11176,770,045 - 177,595,012 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21196,939,349 - 197,065,369 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MDGA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12423,853,710 - 24,705,276 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2423,856,533 - 24,318,531 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605312,230,959 - 13,075,887 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mdga2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473120,951,954 - 21,754,936 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473120,951,651 - 21,760,267 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mdga2
3977 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:68
Count of miRNA genes:59
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000000767
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)681132889104393926Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)683190345106747639Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat

Markers in Region
D6Rat104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,311,061 - 85,311,189 (+)MAPPERmRatBN7.2
Rnor_6.0688,996,335 - 88,996,462NCBIRnor6.0
Rnor_5.0698,477,922 - 98,478,049UniSTSRnor5.0
RGSC_v3.4688,723,450 - 88,723,578RGDRGSC3.4
RGSC_v3.4688,723,451 - 88,723,578UniSTSRGSC3.4
RGSC_v3.1688,726,906 - 88,727,034RGD
Celera683,844,029 - 83,844,156UniSTS
SHRSP x BN Map652.2299UniSTS
SHRSP x BN Map652.2299RGD
FHH x ACI Map662.43RGD
Cytogenetic Map6q24UniSTS
D6Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2684,981,008 - 84,981,246 (+)MAPPERmRatBN7.2
Rnor_6.0688,671,358 - 88,671,595NCBIRnor6.0
Rnor_5.0698,152,816 - 98,153,053UniSTSRnor5.0
RGSC_v3.4688,391,205 - 88,391,443RGDRGSC3.4
RGSC_v3.4688,391,206 - 88,391,443UniSTSRGSC3.4
RGSC_v3.1688,394,662 - 88,394,899RGD
Celera683,515,888 - 83,516,125UniSTS
RH 3.4 Map6582.7UniSTS
RH 3.4 Map6582.7RGD
RH 2.0 Map6810.0RGD
Cytogenetic Map6q24UniSTS
D6Got103  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,094,333 - 85,094,590 (+)MAPPERmRatBN7.2
Rnor_6.0688,780,298 - 88,780,554NCBIRnor6.0
Rnor_5.0698,261,756 - 98,262,012UniSTSRnor5.0
RGSC_v3.4688,504,522 - 88,504,779RGDRGSC3.4
RGSC_v3.4688,504,523 - 88,504,779UniSTSRGSC3.4
RGSC_v3.1688,507,979 - 88,508,235RGD
Celera683,627,621 - 83,627,877UniSTS
RH 3.4 Map6591.5UniSTS
RH 3.4 Map6591.5RGD
RH 2.0 Map6817.4RGD
Cytogenetic Map6q24UniSTS
RH144396  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,008,859 - 85,009,117 (+)MAPPERmRatBN7.2
Rnor_6.0688,697,746 - 88,698,003NCBIRnor6.0
Rnor_5.0698,179,204 - 98,179,461UniSTSRnor5.0
RGSC_v3.4688,419,054 - 88,419,311UniSTSRGSC3.4
Celera683,542,661 - 83,542,918UniSTS
RH 3.4 Map6580.3UniSTS
Cytogenetic Map6q24UniSTS
RH144515  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,212,323 - 85,212,562 (+)MAPPERmRatBN7.2
Rnor_6.0688,898,084 - 88,898,322NCBIRnor6.0
Rnor_5.0698,380,320 - 98,380,558UniSTSRnor5.0
RGSC_v3.4688,623,384 - 88,623,622UniSTSRGSC3.4
Celera683,745,608 - 83,745,846UniSTS
RH 3.4 Map6577.4UniSTS
Cytogenetic Map6q24UniSTS
AW530832  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2684,766,737 - 84,766,908 (+)MAPPERmRatBN7.2
Rnor_6.0688,452,546 - 88,452,716NCBIRnor6.0
Rnor_5.0697,936,381 - 97,936,551UniSTSRnor5.0
RGSC_v3.4688,160,239 - 88,160,409UniSTSRGSC3.4
Celera683,303,051 - 83,303,221UniSTS
RH 3.4 Map6587.3UniSTS
Cytogenetic Map6q24UniSTS
RH138320  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,388,051 - 85,388,177 (+)MAPPERmRatBN7.2
Rnor_6.0689,072,354 - 89,072,479NCBIRnor6.0
Rnor_5.0698,553,941 - 98,554,066UniSTSRnor5.0
RGSC_v3.4688,800,671 - 88,800,796UniSTSRGSC3.4
Celera683,921,238 - 83,921,363UniSTS
Cytogenetic Map6q24UniSTS
Satt124  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2685,582,214 - 85,583,701 (+)MAPPERmRatBN7.2
mRatBN7.2685,582,214 - 85,583,702 (+)MAPPERmRatBN7.2
Rnor_6.0689,266,013 - 89,267,500NCBIRnor6.0
Rnor_6.0689,266,013 - 89,267,499NCBIRnor6.0
Rnor_5.0698,747,313 - 98,748,800UniSTSRnor5.0
Rnor_5.0698,747,313 - 98,748,799UniSTSRnor5.0
RGSC_v3.4688,994,685 - 88,996,171UniSTSRGSC3.4
RGSC_v3.4688,994,685 - 88,996,172UniSTSRGSC3.4
Celera684,114,943 - 84,116,424UniSTS
Celera684,114,943 - 84,116,423UniSTS
Cytogenetic Map6q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 42 3
Low 1 8 4 6 4 30 17 34 11
Below cutoff 2 34 21 12 10 12 8 9 2 14 4 8

Sequence


RefSeq Acc Id: ENSRNOT00000000767   ⟹   ENSRNOP00000000767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl684,761,941 - 85,608,126 (-)Ensembl
Rnor_6.0 Ensembl688,447,749 - 88,917,070 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116494   ⟹   ENSRNOP00000092110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl684,761,941 - 85,608,126 (-)Ensembl
RefSeq Acc Id: NM_199269   ⟹   NP_954890
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,498,084 - 91,344,393 (-)NCBI
mRatBN7.2684,761,906 - 85,608,231 (-)NCBI
Rnor_6.0688,447,714 - 89,292,027 (-)NCBI
Rnor_5.0697,916,163 - 98,773,394 (-)NCBI
RGSC_v3.4688,155,407 - 89,020,699 (-)RGD
Celera683,298,219 - 84,140,941 (-)RGD
Sequence:
RefSeq Acc Id: XM_008764688   ⟹   XP_008762910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,482,687 - 91,346,784 (-)NCBI
mRatBN7.2684,746,422 - 85,608,638 (-)NCBI
Rnor_6.0688,442,620 - 89,292,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112248   ⟹   XP_038968176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,503,294 - 91,346,784 (-)NCBI
mRatBN7.2684,767,112 - 85,608,640 (-)NCBI
RefSeq Acc Id: XR_001838167
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,482,687 - 91,346,784 (-)NCBI
mRatBN7.2684,746,422 - 85,608,638 (-)NCBI
Rnor_6.0688,442,620 - 89,292,453 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001838168
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8690,482,687 - 91,346,784 (-)NCBI
mRatBN7.2684,746,422 - 85,608,638 (-)NCBI
Rnor_6.0688,442,620 - 89,292,453 (-)NCBI
Sequence:
RefSeq Acc Id: NP_954890   ⟸   NM_199269
- Peptide Label: precursor
- UniProtKB: P60756 (UniProtKB/Swiss-Prot),   A0A0H2UH93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008762910   ⟸   XM_008764688
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AD32 (UniProtKB/TrEMBL),   A0A0H2UH93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000000767   ⟸   ENSRNOT00000000767
RefSeq Acc Id: XP_038968176   ⟸   XM_039112248
- Peptide Label: isoform X2
- UniProtKB: A0A0H2UH93 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000092110   ⟸   ENSRNOT00000116494
Protein Domains
Fibronectin type-III   Ig-like   MAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P60756-F1-model_v2 AlphaFold P60756 1-949 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735131 AgrOrtholog
BioCyc Gene G2FUF-37293 BioCyc
Ensembl Genes ENSRNOG00000000618 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055009329 UniProtKB/Swiss-Prot
  ENSRNOG00060007057 UniProtKB/Swiss-Prot
  ENSRNOG00065007466 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000000767 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000000767.6 UniProtKB/Swiss-Prot
  ENSRNOT00000116494.1 UniProtKB/TrEMBL
  ENSRNOT00055015812 UniProtKB/Swiss-Prot
  ENSRNOT00060011618 UniProtKB/Swiss-Prot
  ENSRNOT00065011685 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:314180 UniProtKB/Swiss-Prot
NCBI Gene 314180 ENTREZGENE
PANTHER IGLON FAMILY OF IMMUNOGLOBULIN SUPERFAMILY-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM DOMAIN CONTAINING GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR 2 UniProtKB/TrEMBL
  PROTEIN AMALGAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mdga2 PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000618 RatGTEx
  ENSRNOG00055009329 RatGTEx
  ENSRNOG00060007057 RatGTEx
  ENSRNOG00065007466 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0H2UH93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AD32 ENTREZGENE, UniProtKB/TrEMBL
  A6HBT8_RAT UniProtKB/TrEMBL
  MDGA2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Mdga2  MAM domain containing glycosylphosphatidylinositol anchor 2  Mamdc1  MAM domain containing glycosylphosphatidylinositol anchor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Mamdc1  MAM domain containing glycosylphosphatidylinositol anchor 2  Mdga2    Symbol and Name updated 1299863 APPROVED