Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of MDGA2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of MDGA2 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MDGA2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MDGA2 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | MDGA2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of MDGA2 gene | CTD | PMID:31601247 | aflatoxin B1 | decreases methylation | ISO | MDGA2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of MDGA2 gene | CTD | PMID:27153756 | allethrin | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of MDGA2 protein | CTD | PMID:34896426 | androgen antagonist | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA | CTD | PMID:25607892 | aristolochic acid A | decreases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MDGA2 mRNA | CTD | PMID:33212167 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of MDGA2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | MDGA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MDGA2 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | MDGA2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MDGA2 5' UTR | CTD | PMID:27901495 | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | bisphenol A | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | bisphenol A | decreases expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of MDGA2 mRNA | CTD | PMID:25181051 | Butylparaben | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | cadmium dichloride | decreases expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | Cadmium Chloride results in decreased expression of MDGA2 mRNA | CTD | PMID:33453195 | CGP 52608 | multiple interactions | ISO | MDGA2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MDGA2 gene] | CTD | PMID:28238834 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDGA2 gene | CTD | PMID:20938992 | cyhalothrin | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of MDGA2 protein | CTD | PMID:34896426 | cypermethrin | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of MDGA2 protein | CTD | PMID:34896426 | DDE | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | dibutyl phthalate | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | enzacamene | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA and [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | epoxiconazole | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of MDGA2 mRNA | CTD | PMID:30319688 | fenvalerate | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of MDGA2 protein | CTD | PMID:34896426 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDGA2 gene | CTD | PMID:20938992 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of MDGA2 mRNA | CTD | PMID:25629700 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDGA2 gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | MDGA2 (Homo sapiens) | 6480464 | Lead affects the expression of MDGA2 mRNA | CTD | PMID:28903495 | linuron | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | methotrexate | affects expression | EXP | | 6480464 | Methotrexate affects the expression of MDGA2 mRNA | CTD | PMID:18502557 | O-methyleugenol | decreases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of MDGA2 mRNA | CTD | PMID:32234424 | paracetamol | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of MDGA2 mRNA | CTD | PMID:25607892 | prochloraz | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | procymidone | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | pyrethrins | affects expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | Pyrethrins affects the expression of MDGA2 mRNA | CTD | PMID:34896426 | resveratrol | multiple interactions | ISO | MDGA2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of MDGA2 mRNA | CTD | PMID:23557933 | sodium arsenite | multiple interactions | ISO | MDGA2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of and affects the splicing of MDGA2 mRNA | CTD | PMID:25879800 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of MDGA2 mRNA | CTD | PMID:36209798 | sodium arsenite | decreases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of MDGA2 protein | CTD | PMID:21925251 | sunitinib | increases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MDGA2 mRNA | CTD | PMID:31533062 | trichloroethene | decreases expression | ISO | Mdga2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of MDGA2 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MDGA2 mRNA | CTD | PMID:24935251 | triclosan | decreases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of MDGA2 mRNA | CTD | PMID:30510588 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of MDGA2 mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | MDGA2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MDGA2 mRNA | CTD | PMID:24935251 | vinclozolin | multiple interactions | ISO | Mdga2 (Rattus norvegicus) | 6480464 | [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of MDGA2 mRNA | CTD | PMID:25607892 | |