Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STRN mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | ISO | Strn (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of STRN mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of STRN mRNA | CTD | PMID:29097150 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of STRN mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Strn (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to STRN promoter] | CTD | PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of STRN mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of STRN mRNA | CTD | PMID:32109520 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of STRN mRNA | CTD | PMID:21061450 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Strn (Mus musculus) | 6480464 | Fenretinide results in decreased expression of STRN mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of STRN mRNA | CTD | PMID:24780913 | aflatoxin B1 | decreases methylation | ISO | STRN (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of STRN gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Tretinoin results in increased expression of STRN mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of STRN mRNA | CTD | PMID:16483693 | antirheumatic drug | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of STRN mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of STRN mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to STRN mRNA] | CTD | PMID:32406909 | atrazine | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Atrazine results in increased expression of STRN mRNA | CTD | PMID:22378314 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of STRN mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | STRN (Homo sapiens) | 6480464 | bisphenol A results in increased expression of STRN protein | CTD | PMID:37567409 | bisphenol A | decreases expression | ISO | Strn (Mus musculus) | 6480464 | bisphenol A results in decreased expression of STRN mRNA | CTD | PMID:33221593 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of STRN mRNA | CTD | PMID:32145629 | caffeine | affects phosphorylation | ISO | STRN (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of STRN protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to STRN gene] | CTD | PMID:28238834 | coumarin | decreases phosphorylation | ISO | STRN (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of STRN protein | CTD | PMID:35688186 | cyclosporin A | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of STRN mRNA | CTD | PMID:20106945 and PMID:25562108 | dorsomorphin | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of STRN mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of STRN mRNA | CTD | PMID:29803840 | entinostat | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | entinostat results in decreased expression of STRN mRNA | CTD | PMID:26272509 | ethanol | affects splicing | ISO | Strn (Mus musculus) | 6480464 | Ethanol affects the splicing of STRN mRNA | CTD | PMID:30319688 | FR900359 | affects phosphorylation | ISO | STRN (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of STRN protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of STRN mRNA | CTD | PMID:33387578 | hydrogen peroxide | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of STRN mRNA | CTD | PMID:18951874 | ivermectin | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of STRN protein | CTD | PMID:32959892 | manganese(II) chloride | increases expression | ISO | Strn (Mus musculus) | 6480464 | manganese chloride results in increased expression of STRN mRNA | CTD | PMID:15295902 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of STRN gene | CTD | PMID:35440735 | methyl methanesulfonate | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of STRN mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of STRN mRNA | CTD | PMID:28001369 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STRN mRNA | CTD | PMID:20360939 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of STRN mRNA | CTD | PMID:25729387 | paracetamol | affects expression | ISO | Strn (Mus musculus) | 6480464 | Acetaminophen affects the expression of STRN mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of STRN mRNA | CTD | PMID:22230336 | phenethyl caffeate | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of STRN mRNA | CTD | PMID:20360939 | phenylmercury acetate | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of STRN mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of STRN mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | Strn (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of STRN mRNA | CTD | PMID:17426115 | potassium chromate | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of STRN mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STRN mRNA | CTD | PMID:22079256 | resveratrol | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of STRN mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | STRN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of STRN mRNA | CTD | PMID:27188386 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of STRN mRNA | CTD | PMID:12734012 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of STRN mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of STRN mRNA | CTD | PMID:25729387 | trichostatin A | increases expression | ISO | STRN (Homo sapiens) | 6480464 | trichostatin A results in increased expression of STRN mRNA | CTD | PMID:24935251 | tungsten | decreases expression | ISO | Strn (Mus musculus) | 6480464 | Tungsten results in decreased expression of STRN mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | STRN (Homo sapiens) | 6480464 | Urethane results in increased expression of STRN mRNA | CTD | PMID:28818685 | valproic acid | decreases methylation | ISO | STRN (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of STRN gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of STRN mRNA | CTD | PMID:28001369 | vincaleukoblastine | affects response to substance | ISO | STRN (Homo sapiens) | 6480464 | STRN protein affects the susceptibility to Vinblastine | CTD | PMID:16217747 | vitamin E | decreases expression | ISO | STRN (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of STRN mRNA | CTD | PMID:19244175 | |