C17h5orf24 (similar to human chromosome 5 open reading frame 24) - Rat Genome Database

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Gene: C17h5orf24 (similar to human chromosome 5 open reading frame 24) Rattus norvegicus
Analyze
Symbol: C17h5orf24 (Ensembl: RGD1566359)
Name: similar to human chromosome 5 open reading frame 24 (Ensembl:similar to RIKEN cDNA B230219D22)
RGD ID: 1566359
Description: Orthologous to human C5orf24 (chromosome 5 open reading frame 24); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498701; RGD1566359; similar to RIKEN cDNA B230219D22; uncharacterized protein LOC498701; UPF0461 protein C5orf24 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,928,209 - 8,938,126 (-)NCBIGRCr8
mRatBN7.2178,923,041 - 8,932,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,922,675 - 8,933,356 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,938,568 - 8,948,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,468,054 - 10,477,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,934,958 - 8,944,895 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,454,121 - 9,464,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,457,719 - 9,458,288 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,561,574 - 11,571,515 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41714,950,864 - 14,968,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera179,004,898 - 9,014,909 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
C17h5orf24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8178,928,209 - 8,938,126 (-)NCBIGRCr8
mRatBN7.2178,923,041 - 8,932,958 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,922,675 - 8,933,356 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,938,568 - 8,948,505 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01710,468,054 - 10,477,993 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0178,934,958 - 8,944,895 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,454,121 - 9,464,076 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,457,719 - 9,458,288 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01711,561,574 - 11,571,515 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41714,950,864 - 14,968,381 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera179,004,898 - 9,014,909 (-)NCBICelera
Cytogenetic Map17p14NCBI
C5orf24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,833,602 - 134,859,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,845,680 - 134,859,735 (+)EnsemblGRCh38hg38GRCh38
GRCh375134,181,370 - 134,195,425 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,209,269 - 134,222,687 (+)NCBINCBI36Build 36hg18NCBI36
Celera5130,309,065 - 130,323,730 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,367,584 - 129,381,643 (+)NCBIHuRef
CHM1_15133,613,998 - 133,628,061 (+)NCBICHM1_1
T2T-CHM13v2.05135,360,554 - 135,386,687 (+)NCBIT2T-CHM13v2.0
B230219D22Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391355,840,937 - 55,851,313 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1355,840,937 - 55,851,313 (+)EnsemblGRCm39 Ensembl
GRCm381355,693,124 - 55,703,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1355,693,124 - 55,703,500 (+)EnsemblGRCm38mm10GRCm38
MGSCv371355,794,485 - 55,804,861 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361355,702,746 - 55,713,122 (+)NCBIMGSCv36mm8
Celera1356,747,801 - 56,758,238 (+)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.06NCBI
LOC102006745
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540830,044,031 - 30,054,015 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540830,043,402 - 30,054,015 (+)NCBIChiLan1.0ChiLan1.0
C4H5orf24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24130,142,790 - 130,156,556 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,282,350 - 128,296,116 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,247,436 - 130,261,173 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,390,786 - 136,404,092 (+)NCBIpanpan1.1PanPan1.1panPan2
C11H5orf24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,913,598 - 22,924,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,920,483 - 22,922,639 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,662,999 - 21,674,347 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01123,720,333 - 23,731,688 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,720,338 - 23,731,688 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,419,597 - 22,430,943 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,285,523 - 22,296,881 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,927,875 - 22,939,230 (+)NCBIUU_Cfam_GSD_1.0
CUNH5orf24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213123,044,958 - 123,055,178 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365972,069,854 - 2,079,441 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365972,069,845 - 2,079,458 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2H5orf24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2137,037,929 - 137,049,447 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12137,037,971 - 137,049,449 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,654,058 - 142,665,529 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH5orf24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,632,974 - 37,647,009 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603440,271,573 - 40,285,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH5orf24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473312,211,551 - 12,218,986 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473312,208,397 - 12,218,942 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C17h5orf24
71 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:522
Count of miRNA genes:254
Interacting mature miRNAs:331
Transcripts:ENSRNOT00000075725
Prediction methods:Microtar, Miranda, Pita, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1581553Pur14Proteinuria QTL 145.30.0001urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)17797996816317111Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat

Markers in Region
RH143067  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,925,467 - 8,925,695 (+)MAPPERmRatBN7.2
Rnor_6.0179,456,548 - 9,456,775NCBIRnor6.0
Rnor_5.01711,564,001 - 11,564,228UniSTSRnor5.0
RGSC_v3.41714,965,875 - 14,966,102UniSTSRGSC3.4
Celera179,007,325 - 9,007,552UniSTS
RH 3.4 Map1777.9UniSTS
Cytogenetic Map17p14UniSTS
AA799607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2178,923,249 - 8,923,448 (+)MAPPERmRatBN7.2
Rnor_6.0179,454,330 - 9,454,528NCBIRnor6.0
Rnor_5.01711,561,783 - 11,561,981UniSTSRnor5.0
RGSC_v3.41714,963,657 - 14,963,855UniSTSRGSC3.4
Celera179,005,107 - 9,005,305UniSTS
RH 3.4 Map1775.8UniSTS
Cytogenetic Map17p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 55 39 19 39 8 10 74 35 38 11 8
Low 1 2 2 2 1 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000075725   ⟹   ENSRNOP00000064148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,923,006 - 8,932,832 (-)Ensembl
Rnor_6.0 Ensembl179,457,719 - 9,458,288 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110894   ⟹   ENSRNOP00000097326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl178,922,675 - 8,933,356 (-)Ensembl
RefSeq Acc Id: NM_001400770   ⟹   NP_001387699
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8178,928,209 - 8,938,126 (-)NCBI
mRatBN7.2178,923,041 - 8,932,958 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001387699 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93958 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000064148.1
  ENSRNOP00000097326
  ENSRNOP00000097326.1
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000064148   ⟸   ENSRNOT00000075725
RefSeq Acc Id: ENSRNOP00000097326   ⟸   ENSRNOT00000110894
RefSeq Acc Id: NP_001387699   ⟸   NM_001400770
- UniProtKB: M0R469 (UniProtKB/TrEMBL),   A6KAQ0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R469-F1-model_v2 AlphaFold M0R469 1-189 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1566359 AgrOrtholog
BioCyc Gene G2FUF-10221 BioCyc
Ensembl Genes ENSRNOG00000047934 Ensembl
  ENSRNOG00000063300 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075725.3 UniProtKB/TrEMBL
  ENSRNOT00000110894 ENTREZGENE
  ENSRNOT00000110894.1 UniProtKB/TrEMBL
InterPro DUF5568 UniProtKB/TrEMBL
KEGG Report rno:498701 UniProtKB/TrEMBL
NCBI Gene 498701 ENTREZGENE
PANTHER PTHR31894 UniProtKB/TrEMBL
  UPF0461 PROTEIN C5ORF24 UniProtKB/TrEMBL
Pfam DUF5568 UniProtKB/TrEMBL
PhenoGen C17h5orf24 PhenoGen
RatGTEx ENSRNOG00000047934 RatGTEx
  ENSRNOG00000063300 RatGTEx
UniProt A6KAQ0 ENTREZGENE, UniProtKB/TrEMBL
  M0R469 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C17h5orf24  similar to human chromosome 5 open reading frame 24  RGD1566359  similar to RIKEN cDNA B230219D22  Symbol and Name Changed 1299863 APPROVED
2022-06-01 RGD1566359  similar to RIKEN cDNA B230219D22  RGD1566359  similar to RIKEN cDNA B230219D22  Data merged from RGD:149736196 737654 PROVISIONAL
2021-08-09 RGD1566359  similar to RIKEN cDNA B230219D22      Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1566359  similar to RIKEN cDNA B230219D22   RGD1566359_predicted  similar to RIKEN cDNA B230219D22 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1566359_predicted  similar to RIKEN cDNA B230219D22 (predicted)  LOC498701  similar to RIKEN cDNA B230219D22  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498701  similar to RIKEN cDNA B230219D22      Symbol and Name status set to provisional 70820 PROVISIONAL