Parn (poly(A)-specific ribonuclease) - Rat Genome Database

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Gene: Parn (poly(A)-specific ribonuclease) Rattus norvegicus
Analyze
Symbol: Parn
Name: poly(A)-specific ribonuclease
RGD ID: 1565449
Description: Predicted to enable several functions, including poly(A)-specific ribonuclease activity; protein kinase binding activity; and telomerase RNA binding activity. Predicted to be involved in RNA metabolic process; regulation of nucleobase-containing compound metabolic process; and regulation of telomerase RNA localization to Cajal body. Is active in glutamatergic synapse and postsynapse. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 6. Orthologous to human PARN (poly(A)-specific ribonuclease); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC360464; poly(A)-specific ribonuclease (deadenylation nuclease); poly(A)-specific ribonuclease PARN; RGD1565449; similar to Parn protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Note: This gene aligns across a gap in the Rnor_6.0 reference genome assembly, and therefore, annotation of this gene is split across NW_007905911.1 and NW_007905912.1 in NCBI's Rattus norvegicus Annotation Release 105. [18 Jun 2015]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,917,830 - 2,055,749 (-)NCBIGRCr8
mRatBN7.2101,410,636 - 1,548,573 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,410,642 - 1,548,560 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,108,223 - 6,245,254 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,320,569 - 34,457,608 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,425,524 - 1,562,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,309,724 - 1,461,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,308,414 - 1,461,269 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010204,485 - 358,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4101,788,754 - 1,925,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10473,716 - 609,470 (-)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Bidirectional control of mRNA translation and synaptic plasticity by the cytoplasmic polyadenylation complex. Udagawa T, etal., Mol Cell. 2012 Jul 27;47(2):253-66. doi: 10.1016/j.molcel.2012.05.016. Epub 2012 Jun 21.
Additional References at PubMed
PMID:15358788   PMID:18337750   PMID:20932473   PMID:22442037   PMID:22658674   PMID:25049417   PMID:26482878   PMID:26950371  


Genomics

Comparative Map Data
Parn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,917,830 - 2,055,749 (-)NCBIGRCr8
mRatBN7.2101,410,636 - 1,548,573 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,410,642 - 1,548,560 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,108,223 - 6,245,254 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,320,569 - 34,457,608 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,425,524 - 1,562,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,309,724 - 1,461,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,308,414 - 1,461,269 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010204,485 - 358,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4101,788,754 - 1,925,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10473,716 - 609,470 (-)NCBICelera
Cytogenetic Map10q11NCBI
PARN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381614,435,701 - 14,630,260 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1614,435,700 - 14,632,728 (-)EnsemblGRCh38hg38GRCh38
GRCh371614,529,558 - 14,724,117 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,437,060 - 14,631,540 (-)NCBINCBI36Build 36hg18NCBI36
Build 341614,437,059 - 14,631,540NCBI
Celera1614,706,337 - 14,900,899 (-)NCBICelera
Cytogenetic Map16p13.12NCBI
HuRef1614,448,361 - 14,642,982 (-)NCBIHuRef
CHM1_11614,529,504 - 14,723,956 (-)NCBICHM1_1
T2T-CHM13v2.01614,473,312 - 14,667,845 (-)NCBIT2T-CHM13v2.0
Parn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,355,828 - 13,486,035 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1613,355,824 - 13,486,034 (-)EnsemblGRCm39 Ensembl
GRCm381613,537,964 - 13,668,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,537,960 - 13,668,170 (-)EnsemblGRCm38mm10GRCm38
MGSCv371613,538,057 - 13,668,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361613,451,542 - 13,581,748 (-)NCBIMGSCv36mm8
Celera1614,141,614 - 14,273,156 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.32NCBI
Parn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,258,692 - 4,422,197 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,255,726 - 4,421,083 (+)NCBIChiLan1.0ChiLan1.0
PARN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21814,972,145 - 15,164,377 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11618,755,003 - 18,947,226 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01613,363,879 - 13,556,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11614,787,881 - 14,977,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1614,787,881 - 14,977,786 (-)Ensemblpanpan1.1panPan2
PARN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,629,137 - 28,783,671 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,629,174 - 28,783,901 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,992,537 - 30,147,919 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,792,691 - 28,948,127 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl628,792,731 - 28,947,297 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1628,595,636 - 28,750,791 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0628,483,721 - 28,639,090 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,891,075 - 29,046,446 (+)NCBIUU_Cfam_GSD_1.0
Parn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344114,569,040 - 114,714,225 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365012,666,874 - 2,810,488 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365012,666,908 - 2,810,159 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,612,269 - 28,802,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,616,808 - 28,802,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2329,618,701 - 29,877,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1513,891,362 - 14,089,576 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl513,891,369 - 14,089,518 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606815,963,884 - 16,163,050 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Parn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,919,965 - 4,093,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,920,042 - 4,092,179 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Parn
996 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:34
Interacting mature miRNAs:34
Transcripts:ENSRNOT00000061644
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat

Markers in Region
D10Rat199  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2101,468,843 - 1,469,029 (+)MAPPERmRatBN7.2
Rnor_6.0101,381,054 - 1,381,239NCBIRnor6.0
Rnor_5.010278,166 - 278,351UniSTSRnor5.0
RGSC_v3.4101,867,586 - 1,867,772RGDRGSC3.4
RGSC_v3.4101,867,587 - 1,867,772UniSTSRGSC3.4
RGSC_v3.1101,867,486 - 1,867,790RGD
Celera10530,195 - 530,380UniSTS
FHH x ACI Map104.54UniSTS
FHH x ACI Map104.54RGD
Cytogenetic Map10q11UniSTS
D10Got229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2101,550,172 - 1,550,398 (+)MAPPERmRatBN7.2
Rnor_6.0101,462,872 - 1,463,097NCBIRnor6.0
Rnor_5.010359,984 - 360,209UniSTSRnor5.0
RGSC_v3.4101,786,780 - 1,787,005UniSTSRGSC3.4
Celera10611,219 - 611,444UniSTS
Cytogenetic Map10q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 22 25 12 18 12 66 22 34 11
Low 21 32 29 1 29 8 11 8 13 7 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039086256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063269278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005489883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ123458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000078421   ⟹   ENSRNOP00000073884
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,410,662 - 1,548,560 (-)Ensembl
Rnor_6.0 Ensembl101,308,864 - 1,461,269 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083125   ⟹   ENSRNOP00000070962
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,494,632 - 1,548,560 (-)Ensembl
Rnor_6.0 Ensembl101,442,283 - 1,461,216 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084447   ⟹   ENSRNOP00000072539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,410,642 - 1,548,560 (-)Ensembl
Rnor_6.0 Ensembl101,308,414 - 1,461,250 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl101,407,876 - 1,414,058 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl101,437,803 - 1,457,787 (-)Ensembl
RefSeq Acc Id: NM_001270415   ⟹   NP_001257344
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,722 (-)NCBI
mRatBN7.2101,410,636 - 1,548,547 (-)NCBI
Rnor_6.0101,309,724 - 1,461,123 (-)NCBI
Rnor_5.010204,485 - 358,376 (-)NCBI
Celera10473,716 - 609,470 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086248   ⟹   XP_038942176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,749 (-)NCBI
mRatBN7.2101,410,636 - 1,548,572 (-)NCBI
RefSeq Acc Id: XM_039086249   ⟹   XP_038942177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,744 (-)NCBI
mRatBN7.2101,410,636 - 1,548,572 (-)NCBI
RefSeq Acc Id: XM_039086250   ⟹   XP_038942178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,744 (-)NCBI
mRatBN7.2101,410,636 - 1,548,573 (-)NCBI
RefSeq Acc Id: XM_039086251   ⟹   XP_038942179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,744 (-)NCBI
mRatBN7.2101,410,636 - 1,548,572 (-)NCBI
RefSeq Acc Id: XM_039086253   ⟹   XP_038942181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,980,461 - 2,055,744 (-)NCBI
mRatBN7.2101,477,581 - 1,548,572 (-)NCBI
RefSeq Acc Id: XM_039086254   ⟹   XP_038942182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,032,572 (-)NCBI
mRatBN7.2101,410,636 - 1,520,617 (-)NCBI
RefSeq Acc Id: XM_039086255   ⟹   XP_038942183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,016,458 (-)NCBI
mRatBN7.2101,410,636 - 1,509,278 (-)NCBI
RefSeq Acc Id: XM_039086256   ⟹   XP_038942184
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,985,814 - 2,055,744 (-)NCBI
mRatBN7.2101,478,633 - 1,548,571 (-)NCBI
RefSeq Acc Id: XM_063269271   ⟹   XP_063125341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,741 (-)NCBI
RefSeq Acc Id: XM_063269272   ⟹   XP_063125342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,742 (-)NCBI
RefSeq Acc Id: XM_063269273   ⟹   XP_063125343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,741 (-)NCBI
RefSeq Acc Id: XM_063269274   ⟹   XP_063125344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,742 (-)NCBI
RefSeq Acc Id: XM_063269275   ⟹   XP_063125345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,055,742 (-)NCBI
RefSeq Acc Id: XM_063269277   ⟹   XP_063125347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,921,704 - 2,055,743 (-)NCBI
RefSeq Acc Id: XM_063269278   ⟹   XP_063125348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,917,830 - 2,032,572 (-)NCBI
RefSeq Acc Id: XR_005489883
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8102,009,720 - 2,055,745 (-)NCBI
mRatBN7.2101,502,528 - 1,548,572 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001257344   ⟸   NM_001270415
- UniProtKB: A0A0G2QC45 (UniProtKB/TrEMBL),   A6K4E3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072539   ⟸   ENSRNOT00000084447
RefSeq Acc Id: ENSRNOP00000073884   ⟸   ENSRNOT00000078421
RefSeq Acc Id: ENSRNOP00000070962   ⟸   ENSRNOT00000083125
RefSeq Acc Id: XP_038942178   ⟸   XM_039086250
- Peptide Label: isoform X3
- UniProtKB: A6K4E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942177   ⟸   XM_039086249
- Peptide Label: isoform X2
- UniProtKB: A6K4E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942179   ⟸   XM_039086251
- Peptide Label: isoform X4
- UniProtKB: A6K4E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942176   ⟸   XM_039086248
- Peptide Label: isoform X1
- UniProtKB: A6K4E3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038942182   ⟸   XM_039086254
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038942183   ⟸   XM_039086255
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038942181   ⟸   XM_039086253
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038942184   ⟸   XM_039086256
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063125345   ⟸   XM_063269275
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063125344   ⟸   XM_063269274
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063125342   ⟸   XM_063269272
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063125341   ⟸   XM_063269271
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063125343   ⟸   XM_063269273
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063125348   ⟸   XM_063269278
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063125347   ⟸   XM_063269277
- Peptide Label: isoform X10
- UniProtKB: A0A0G2K386 (UniProtKB/TrEMBL),   A0A0G2K6N8 (UniProtKB/TrEMBL)
Protein Domains
R3H

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K6N8-F1-model_v2 AlphaFold A0A0G2K6N8 1-642 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696928
Promoter ID:EPDNEW_R7449
Type:multiple initiation site
Name:Parn_1
Description:poly-specific ribonuclease
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0101,461,245 - 1,461,305EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565449 AgrOrtholog
BioCyc Gene G2FUF-26226 BioCyc
Ensembl Genes ENSRNOG00000002912 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078421 ENTREZGENE
  ENSRNOT00000078421.3 UniProtKB/TrEMBL
  ENSRNOT00000083125.3 UniProtKB/TrEMBL
  ENSRNOT00000084447.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
  R3H-like domain UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PARN_R3H UniProtKB/TrEMBL
  PolyA-riboNase_RNA_binding UniProtKB/TrEMBL
  PolynucTfrase_RNaseH_fold UniProtKB/TrEMBL
  R3H_dom_sf UniProtKB/TrEMBL
  R3H_ss-bd UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RNase_CAF1 UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report rno:360464 UniProtKB/TrEMBL
NCBI Gene 360464 ENTREZGENE
PANTHER POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 UniProtKB/TrEMBL
  POLY(A)-SPECIFIC RIBONUCLEASE PARN UniProtKB/TrEMBL
Pfam CAF1 UniProtKB/TrEMBL
  RNA_bind UniProtKB/TrEMBL
PhenoGen Parn PhenoGen
PROSITE R3H UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002912 RatGTEx
Superfamily-SCOP RNaseH_fold UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
  SSF82708 UniProtKB/TrEMBL
UniProt A0A0G2JZ98_RAT UniProtKB/TrEMBL
  A0A0G2K386 ENTREZGENE
  A0A0G2K6N8 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2QC45 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8Y7Y5_RAT UniProtKB/TrEMBL
  A6K4E3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2K386 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Parn  poly(A)-specific ribonuclease  Parn  poly(A)-specific ribonuclease (deadenylation nuclease)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Parn  poly(A)-specific ribonuclease (deadenylation nuclease)  RGD1565449_predicted  similar to Parn protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1565449_predicted  similar to Parn protein (predicted)  LOC360464  similar to Parn protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC360464  similar to Parn protein      Symbol and Name status set to provisional 70820 PROVISIONAL