Parn (poly(A)-specific ribonuclease) - Rat Genome Database

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Gene: Parn (poly(A)-specific ribonuclease) Heterocephalus glaber
Analyze
Symbol: Parn
Name: poly(A)-specific ribonuclease
RGD ID: 18928933
Description: ENCODES a protein that exhibits telomerase RNA binding (ortholog); INVOLVED IN nuclear-transcribed mRNA poly(A) tail shortening (ortholog); ASSOCIATED WITH autosomal recessive dyskeratosis congenita 6 (ortholog); dyskeratosis congenita (ortholog); genetic disease (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: poly(A)-specific ribonuclease PARN
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,919,965 - 4,093,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,920,042 - 4,092,179 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Parn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247823,919,965 - 4,093,743 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247823,920,042 - 4,092,179 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PARN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381614,435,701 - 14,630,260 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1614,435,700 - 14,632,728 (-)EnsemblGRCh38hg38GRCh38
GRCh371614,529,558 - 14,724,117 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,437,060 - 14,631,540 (-)NCBINCBI36Build 36hg18NCBI36
Build 341614,437,059 - 14,631,540NCBI
Celera1614,706,337 - 14,900,899 (-)NCBICelera
Cytogenetic Map16p13.12NCBI
HuRef1614,448,361 - 14,642,982 (-)NCBIHuRef
CHM1_11614,529,504 - 14,723,956 (-)NCBICHM1_1
T2T-CHM13v2.01614,473,312 - 14,667,845 (-)NCBIT2T-CHM13v2.0
Parn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,355,828 - 13,486,035 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1613,355,824 - 13,486,034 (-)EnsemblGRCm39 Ensembl
GRCm381613,537,964 - 13,668,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,537,960 - 13,668,170 (-)EnsemblGRCm38mm10GRCm38
MGSCv371613,538,057 - 13,668,263 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361613,451,542 - 13,581,748 (-)NCBIMGSCv36mm8
Celera1614,141,614 - 14,273,156 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.32NCBI
Parn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,917,830 - 2,055,749 (-)NCBIGRCr8
mRatBN7.2101,410,636 - 1,548,573 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,410,642 - 1,548,560 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,108,223 - 6,245,254 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,320,569 - 34,457,608 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,425,524 - 1,562,262 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0101,309,724 - 1,461,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl101,308,414 - 1,461,269 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010204,485 - 358,376 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4101,788,754 - 1,925,032 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera10473,716 - 609,470 (-)NCBICelera
Cytogenetic Map10q11NCBI
Parn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554424,258,692 - 4,422,197 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554424,255,726 - 4,421,083 (+)NCBIChiLan1.0ChiLan1.0
PARN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21814,972,145 - 15,164,377 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11618,755,003 - 18,947,226 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01613,363,879 - 13,556,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11614,787,881 - 14,977,786 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1614,787,881 - 14,977,786 (-)Ensemblpanpan1.1panPan2
PARN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,629,137 - 28,783,671 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,629,174 - 28,783,901 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha629,992,537 - 30,147,919 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0628,792,691 - 28,948,127 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl628,792,731 - 28,947,297 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1628,595,636 - 28,750,791 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0628,483,721 - 28,639,090 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0628,891,075 - 29,046,446 (+)NCBIUU_Cfam_GSD_1.0
Parn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344114,569,040 - 114,714,225 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365012,666,874 - 2,810,488 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365012,666,908 - 2,810,159 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl328,612,269 - 28,802,504 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1328,616,808 - 28,802,506 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2329,618,701 - 29,877,403 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1513,891,362 - 14,089,576 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl513,891,369 - 14,089,518 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606815,963,884 - 16,163,050 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000015364   ⟹   ENSHGLP00000015209
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247823,919,965 - 4,093,743 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000015365   ⟹   ENSHGLP00000015210
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247823,920,195 - 4,091,210 (+)Ensembl
RefSeq Acc Id: XM_004855840   ⟹   XP_004855897
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247823,920,045 - 4,092,179 (+)NCBI
RefSeq Acc Id: XM_021237242   ⟹   XP_021092901
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247823,920,044 - 4,092,179 (+)NCBI
RefSeq Acc Id: XM_021237243   ⟹   XP_021092902
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247823,929,747 - 4,092,179 (+)NCBI
RefSeq Acc Id: XM_021237244   ⟹   XP_021092903
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247823,920,042 - 4,027,763 (+)NCBI
RefSeq Acc Id: XM_021237245   ⟹   XP_021092904
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247823,920,042 - 4,031,226 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004855897 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092901 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092902 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092903 (Get FASTA)   NCBI Sequence Viewer  
  XP_021092904 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000015209
GenBank Protein JAO02024 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021092904   ⟸   XM_021237245
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021092903   ⟸   XM_021237244
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021092901   ⟸   XM_021237242
- Peptide Label: isoform X1
- UniProtKB: G5B4F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855897   ⟸   XM_004855840
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JER7 (UniProtKB/TrEMBL),   G5B4F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092902   ⟸   XM_021237243
- Peptide Label: isoform X3
- UniProtKB: G5B4F1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000015209   ⟸   ENSHGLT00000015364
RefSeq Acc Id: ENSHGLP00000015210   ⟸   ENSHGLT00000015365


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000010886 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000015364 ENTREZGENE
Gene3D-CATH 3.30.420.10 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  PARN_R3H UniProtKB/TrEMBL
  PolyA-riboNase_RNA-binding UniProtKB/TrEMBL
  R3H_dom UniProtKB/TrEMBL
  R3H_dom_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RNase_CAF1 UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/TrEMBL
KEGG Report hgl:101715275 UniProtKB/TrEMBL
NCBI Gene Parn ENTREZGENE
PANTHER POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 UniProtKB/TrEMBL
  POLY(A)-SPECIFIC RIBONUCLEASE PARN UniProtKB/TrEMBL
Pfam CAF1 UniProtKB/TrEMBL
  RNA_bind UniProtKB/TrEMBL
PROSITE R3H UniProtKB/TrEMBL
Superfamily-SCOP SSF53098 UniProtKB/TrEMBL
  SSF54928 UniProtKB/TrEMBL
  SSF82708 UniProtKB/TrEMBL
UniProt A0A0P6JER7 ENTREZGENE, UniProtKB/TrEMBL
  G5B4F1 ENTREZGENE, UniProtKB/TrEMBL