Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CAR5B mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Car5b (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of CAR5B mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Car5b (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CAR5B mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | Estradiol results in decreased expression of CA5B mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Car5b (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CAR5B mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CAR5B promoter] | CTD | PMID:17942748 and PMID:19654925 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CAR5B mRNA | CTD | PMID:22808131 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | CA5B (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of CA5B gene | CTD | PMID:31601247 | 4,4'-sulfonyldiphenol | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | bisphenol S results in increased expression of CA5B protein | CTD | PMID:34186270 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | Fenretinide results in decreased expression of CA5B mRNA | CTD | PMID:28973697 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of CA5B mRNA | CTD | PMID:31881176 | acetazolamide | multiple interactions | ISO | CA5B (Homo sapiens) | 6480464 | Acetazolamide binds to and results in decreased activity of CA5B protein | CTD | PMID:28251759 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of CA5B mRNA | CTD | PMID:33354967 | all-trans-retinoic acid | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of CA5B mRNA | CTD | PMID:33167477 | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CAR5B mRNA | CTD | PMID:35163327 | arsane | affects methylation | ISO | CA5B (Homo sapiens) | 6480464 | Arsenic affects the methylation of CA5B gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | CA5B (Homo sapiens) | 6480464 | Arsenic affects the methylation of CA5B gene | CTD | PMID:25304211 | arsenite(3-) | increases methylation | ISO | CA5B (Homo sapiens) | 6480464 | arsenite results in increased methylation of CA5B promoter | CTD | PMID:23974009 | atrazine | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Atrazine results in increased expression of CA5B mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | Car5b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of CAR5B mRNA | CTD | PMID:21569818 | benzo[a]pyrene | decreases methylation | ISO | CA5B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of CA5B 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | CA5B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CA5B promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of CAR5B mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CA5B mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CA5B protein | CTD | PMID:34186270 | Bisphenol B | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | bisphenol B results in increased expression of CA5B protein | CTD | PMID:34186270 | bisphenol F | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | bisphenol F results in increased expression of CA5B protein | CTD | PMID:34186270 | butanal | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of CA5B mRNA | CTD | PMID:26079696 | cisplatin | multiple interactions | ISO | Car5b (Mus musculus) | 6480464 | [Cisplatin co-treated with RELB mutant form co-treated with TNF protein] results in decreased expression of CAR5B mRNA | CTD | PMID:23625948 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of CA5B mRNA | CTD | PMID:21865292 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of CA5B mRNA | CTD | PMID:21551480 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CAR5B mRNA | CTD | PMID:29391264 | ethanol | increases expression | ISO | Car5b (Mus musculus) | 6480464 | Ethanol results in increased expression of CAR5B mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of CA5B mRNA | CTD | PMID:21867686 | furan | decreases expression | EXP | | 6480464 | furan results in decreased expression of CAR5B mRNA | CTD | PMID:25539665 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CAR5B mRNA | CTD | PMID:27387713 | genistein | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | Genistein results in decreased expression of CAR5B mRNA | CTD | PMID:22553218 | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of CA5B gene | CTD | PMID:31011160 | manganese(II) chloride | decreases expression | EXP | | 6480464 | manganese chloride results in decreased expression of CAR5B mRNA | CTD | PMID:28801915 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of CAR5B mRNA | CTD | PMID:19149911 | methamphetamine | multiple interactions | EXP | | 6480464 | Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA] | CTD | PMID:19149911 | methylmercury chloride | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of CA5B mRNA | CTD | PMID:28001369 | monosodium L-glutamate | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | Sodium Glutamate results in decreased expression of CAR5B mRNA | CTD | PMID:22078008 | oryzalin | multiple interactions | ISO | CA5B (Homo sapiens) | 6480464 | oryzalin binds to and results in decreased activity of CA5B protein | CTD | PMID:28251759 | ozone | multiple interactions | ISO | CA5B (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of CA5B mRNA | CTD | PMID:35430440 | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of CAR5B mRNA | CTD | PMID:35163327 | perfluorooctanoic acid | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of CA5B mRNA | CTD | PMID:36326898 | phenformin | decreases expression | EXP | | 6480464 | Phenformin results in decreased expression of CAR5B mRNA | CTD | PMID:31324951 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of CAR5B mRNA | CTD | PMID:28374803 | senecionine | increases expression | ISO | Car5b (Mus musculus) | 6480464 | senecionine results in increased expression of CA5B protein | CTD | PMID:35357534 | silicon dioxide | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of CA5B mRNA | CTD | PMID:23806026 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of CA5B mRNA | CTD | PMID:27257137 | sunitinib | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Sunitinib results in increased expression of CA5B mRNA | CTD | PMID:31533062 | thapsigargin | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of CA5B mRNA | CTD | PMID:22378314 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of CA5B mRNA and Thioacetamide results in decreased expression of CAR5B mRNA | CTD | PMID:23411599 and PMID:34492290 | titanium dioxide | decreases expression | ISO | Car5b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of CAR5B mRNA | CTD | PMID:23557971 | triclosan | decreases expression | ISO | CA5B (Homo sapiens) | 6480464 | Triclosan results in decreased expression of CA5B mRNA | CTD | PMID:30510588 | trimellitic anhydride | increases expression | ISO | Car5b (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of CAR5B mRNA | CTD | PMID:19042947 | tunicamycin | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of CA5B mRNA | CTD | PMID:22378314 | valproic acid | multiple interactions | EXP | | 6480464 | Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA] | CTD | PMID:19149911 | valproic acid | increases expression | ISO | CA5B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of CA5B mRNA | CTD | PMID:28001369 | |