Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in increased expression of RGMA mRNA | CTD | PMID:27840820 | 1,2-dimethylhydrazine | increases expression | ISO | Rgma (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of RGMA mRNA | CTD | PMID:22206623 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of RGMA mRNA | CTD | PMID:30723492 | 17alpha-ethynylestradiol | multiple interactions | ISO | Rgma (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGMA mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Rgma (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of RGMA mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of RGMA mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rgma (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RGMA mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RGMA mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGMA (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RGMA mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rgma (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RGMA mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of RGMA mRNA | CTD | PMID:25172293 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RGMA mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RGMA mRNA | CTD | PMID:28628672 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RGMA mRNA | CTD | PMID:30047161 and PMID:36843608 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of RGMA mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of RGMA mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of RGMA mRNA | CTD | PMID:21641981 | aflatoxin B1 | increases methylation | ISO | RGMA (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of RGMA 3' UTR more ... | CTD | PMID:27153756 and PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RGMA mRNA | CTD | PMID:21934132 and PMID:23724009 | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RGMA mRNA | CTD | PMID:35163327 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of RGMA mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RGMA mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGMA (Homo sapiens) | 6480464 | Arsenic affects the methylation of RGMA gene | CTD | PMID:25304211 | arsane | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RGMA mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RGMA mRNA | CTD | PMID:32525701 | arsenic atom | affects methylation | ISO | RGMA (Homo sapiens) | 6480464 | Arsenic affects the methylation of RGMA gene | CTD | PMID:25304211 | atrazine | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Atrazine results in increased expression of RGMA mRNA | CTD | PMID:22378314 | benzo[a]pyrene | multiple interactions | ISO | Rgma (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of RGMA mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of RGMA mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGMA (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of RGMA intron and Benzo(a)pyrene affects the methylation of RGMA promoter | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | RGMA (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of RGMA 3' UTR and Benzo(a)pyrene results in increased methylation of RGMA exon | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Rgma (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RGMA mRNA | CTD | PMID:22228805 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of RGMA mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RGMA mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Rgma (Mus musculus) | 6480464 | bisphenol A results in increased expression of RGMA mRNA | CTD | PMID:32156529 and PMID:34585602 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RGMA mRNA | CTD | PMID:30816183 | bisphenol A | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RGMA mRNA | CTD | PMID:28628672 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of RGMA gene | CTD | PMID:28505145 | bisphenol A | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RGMA mRNA | CTD | PMID:27685785 | bisphenol F | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RGMA mRNA | CTD | PMID:28628672 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of RGMA mRNA | CTD | PMID:32479839 | butanal | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of RGMA mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RGMA mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of RGMA mRNA | CTD | PMID:35301059 | cantharidin | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | Cantharidin results in decreased expression of RGMA mRNA | CTD | PMID:36907384 | carbamazepine | affects expression | ISO | RGMA (Homo sapiens) | 6480464 | Carbamazepine affects the expression of RGMA mRNA | CTD | PMID:25979313 | CGP 52608 | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RGMA gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Rgma (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of RGMA mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of RGMA mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Cisplatin results in increased expression of RGMA mRNA | CTD | PMID:27392435 | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of RGMA mRNA | CTD | PMID:26577399 | dexamethasone | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | Dexamethasone results in decreased expression of RGMA mRNA | CTD | PMID:22733784 | dexamethasone | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RGMA mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RGMA mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RGMA mRNA | CTD | PMID:30031762 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of RGMA mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of RGMA mRNA | CTD | PMID:35436446 | ethanol | increases expression | ISO | Rgma (Mus musculus) | 6480464 | Ethanol results in increased expression of RGMA mRNA | CTD | PMID:30319688 | folic acid | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of RGMA mRNA | CTD | PMID:21867686 | fulvestrant | increases methylation | ISO | RGMA (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of RGMA gene | CTD | PMID:31601247 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of RGMA mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RGMA mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RGMA mRNA | CTD | PMID:28628672 | Licochalcone B | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | licochalcone B results in increased expression of RGMA mRNA | CTD | PMID:33647349 | mercury dibromide | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | mercuric bromide results in decreased expression of RGMA mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of RGMA mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of RGMA gene | CTD | PMID:35440735 | methylmercury chloride | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of RGMA mRNA | CTD | PMID:28001369 | methylphenidate | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | Methylphenidate results in decreased expression of RGMA mRNA | CTD | PMID:22470460 | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of RGMA mRNA | CTD | PMID:25566086 | niclosamide | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of RGMA mRNA | CTD | PMID:36318118 | p-chloromercuribenzoic acid | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of RGMA mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | panobinostat | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | panobinostat | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | panobinostat results in decreased expression of RGMA mRNA | CTD | PMID:26272509 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of RGMA mRNA | CTD | PMID:32680482 | PCB138 | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of RGMA mRNA | CTD | PMID:35163327 | phenylmercury acetate | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of RGMA mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | propanal | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of RGMA mRNA | CTD | PMID:26079696 | SB 431542 | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | silicon dioxide | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of RGMA mRNA | CTD | PMID:25895662 | silver atom | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | Silver results in decreased expression of RGMA mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | Silver results in decreased expression of RGMA mRNA | CTD | PMID:27131904 | sodium arsenate | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of RGMA mRNA | CTD | PMID:32525701 | tetrachloromethane | affects expression | ISO | Rgma (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of RGMA mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of RGMA mRNA | CTD | PMID:31150632 | thapsigargin | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Thapsigargin results in decreased expression of RGMA mRNA | CTD | PMID:29453283 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of RGMA mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of RGMA mRNA | CTD | PMID:22723015 more ... | trichostatin A | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | triclosan | increases methylation | ISO | RGMA (Homo sapiens) | 6480464 | Triclosan results in increased methylation of RGMA gene | CTD | PMID:34523531 | trimellitic anhydride | decreases expression | ISO | Rgma (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of RGMA mRNA | CTD | PMID:19042947 | urethane | increases expression | ISO | RGMA (Homo sapiens) | 6480464 | Urethane results in increased expression of RGMA mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Rgma (Mus musculus) | 6480464 | Valproic Acid affects the expression of RGMA mRNA | CTD | PMID:17963808 | valproic acid | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | valproic acid | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RGMA mRNA | CTD | PMID:23179753 more ... | valproic acid | decreases methylation | ISO | RGMA (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of RGMA gene | CTD | PMID:29154799 | vorinostat | multiple interactions | ISO | RGMA (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RGMA mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | RGMA (Homo sapiens) | 6480464 | vorinostat results in decreased expression of RGMA mRNA | CTD | PMID:26272509 | zaragozic acid A | decreases expression | EXP | | 6480464 | squalestatin 1 results in decreased expression of RGMA mRNA | CTD | PMID:27225895 | zaragozic acid A | increases expression | ISO | Rgma (Mus musculus) | 6480464 | squalestatin 1 results in increased expression of RGMA mRNA | CTD | PMID:27225895 | |