Smc6 (structural maintenance of chromosomes 6) - Rat Genome Database

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Gene: Smc6 (structural maintenance of chromosomes 6) Rattus norvegicus
Analyze
Symbol: Smc6
Name: structural maintenance of chromosomes 6
RGD ID: 1311214
Description: Predicted to enable DNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including DNA recombination; cellular senescence; and negative regulation by host of viral genome replication. Predicted to be located in chromosome; mitotic spindle pole; and nuclear body. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus and site of double-strand break. Orthologous to human SMC6 (structural maintenance of chromosomes 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC313961; SMC6 structural maintenance of chromosomes 6-like 1; SMC6 structural maintenance of chromosomes 6-like 1 (yeast); Smc6l1; structural maintenance of chromosomes protein 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8639,697,810 - 39,752,275 (+)NCBIGRCr8
mRatBN7.2633,978,730 - 34,033,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl633,978,716 - 34,031,746 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx634,271,336 - 34,324,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0634,587,277 - 34,640,243 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0634,058,056 - 34,111,010 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0636,941,233 - 36,995,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl636,941,233 - 36,995,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0646,691,346 - 46,746,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4634,710,177 - 34,763,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1634,718,849 - 34,765,945 (+)NCBI
Celera633,379,218 - 33,432,201 (+)NCBICelera
Cytogenetic Map6q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11408570   PMID:17589526   PMID:18086888   PMID:25931565  


Genomics

Comparative Map Data
Smc6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8639,697,810 - 39,752,275 (+)NCBIGRCr8
mRatBN7.2633,978,730 - 34,033,201 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl633,978,716 - 34,031,746 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx634,271,336 - 34,324,302 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0634,587,277 - 34,640,243 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0634,058,056 - 34,111,010 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0636,941,233 - 36,995,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl636,941,233 - 36,995,138 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0646,691,346 - 46,746,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4634,710,177 - 34,763,158 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1634,718,849 - 34,765,945 (+)NCBI
Celera633,379,218 - 33,432,201 (+)NCBICelera
Cytogenetic Map6q15NCBI
SMC6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38217,663,812 - 17,753,810 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl217,663,812 - 17,800,242 (-)EnsemblGRCh38hg38GRCh38
GRCh37217,845,079 - 17,935,077 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36217,708,562 - 17,798,541 (-)NCBINCBI36Build 36hg18NCBI36
Build 34217,766,708 - 17,856,688NCBI
Celera217,724,884 - 17,815,383 (-)NCBICelera
Cytogenetic Map2p24.2NCBI
HuRef217,620,169 - 17,710,162 (-)NCBIHuRef
CHM1_1217,774,474 - 17,864,475 (-)NCBICHM1_1
T2T-CHM13v2.0217,695,556 - 17,785,539 (-)NCBIT2T-CHM13v2.0
Smc6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391211,315,887 - 11,369,786 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1211,315,887 - 11,369,786 (+)EnsemblGRCm39 Ensembl
GRCm381211,265,886 - 11,319,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1211,265,886 - 11,319,785 (+)EnsemblGRCm38mm10GRCm38
MGSCv371211,272,692 - 11,326,591 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361211,292,229 - 11,346,128 (+)NCBIMGSCv36mm8
Celera1211,610,123 - 11,665,032 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map125.58NCBI
Smc6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955469453,353 - 552,279 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955469456,023 - 552,794 (-)NCBIChiLan1.0ChiLan1.0
SMC6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212108,728,947 - 108,861,156 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A108,732,913 - 108,874,819 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A17,648,371 - 17,735,910 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A17,774,590 - 17,861,920 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A17,776,276 - 17,854,052 (-)Ensemblpanpan1.1panPan2
SMC6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11713,132,945 - 13,201,214 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1713,133,236 - 13,201,759 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1713,085,159 - 13,153,159 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01713,269,396 - 13,337,856 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1713,269,693 - 13,337,904 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11713,127,707 - 13,196,134 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01713,138,902 - 13,207,328 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01713,165,157 - 13,233,234 (-)NCBIUU_Cfam_GSD_1.0
Smc6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629257,587,323 - 57,648,207 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649313,191,455 - 13,252,578 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649313,191,389 - 13,250,788 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMC6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3120,097,379 - 120,170,971 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13120,097,361 - 120,170,974 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23128,245,265 - 128,318,831 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SMC6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11489,917,621 - 90,005,604 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1489,917,518 - 90,000,088 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604522,208,586 - 22,296,770 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smc6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624738614,402 - 681,430 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624738612,758 - 689,191 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smc6
114 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:187
Count of miRNA genes:144
Interacting mature miRNAs:156
Transcripts:ENSRNOT00000007073
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
634318Bw118Body weight QTL 1183.55abdominal fat pad mass (VT:1000711)abdominal fat pad weight (CMO:0000088)63330954957730294Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat

Markers in Region
RH143232  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2634,027,678 - 34,027,817 (+)MAPPERmRatBN7.2
Rnor_6.0636,990,398 - 36,990,536NCBIRnor6.0
Rnor_5.0646,740,511 - 46,740,649UniSTSRnor5.0
RGSC_v3.4634,759,091 - 34,759,229UniSTSRGSC3.4
Celera633,428,134 - 33,428,272UniSTS
RH 3.4 Map6144.2UniSTS
Cytogenetic Map6q14UniSTS
RH143724  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2633,977,895 - 33,978,065 (+)MAPPERmRatBN7.2
Rnor_6.0636,940,363 - 36,940,532NCBIRnor6.0
Rnor_5.0646,690,476 - 46,690,645UniSTSRnor5.0
RGSC_v3.4634,709,307 - 34,709,476UniSTSRGSC3.4
Celera633,378,348 - 33,378,517UniSTS
RH 3.4 Map6145.4UniSTS
Cytogenetic Map6q14UniSTS
BF387143  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2633,979,868 - 33,980,064 (+)MAPPERmRatBN7.2
Rnor_6.0636,942,336 - 36,942,531NCBIRnor6.0
Rnor_5.0646,692,449 - 46,692,644UniSTSRnor5.0
RGSC_v3.4634,711,280 - 34,711,475UniSTSRGSC3.4
Celera633,380,321 - 33,380,516UniSTS
Cytogenetic Map6q14UniSTS
RH139846  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2634,032,829 - 34,033,011 (+)MAPPERmRatBN7.2
Rnor_6.0636,995,549 - 36,995,730NCBIRnor6.0
Rnor_5.0646,745,662 - 46,745,843UniSTSRnor5.0
RGSC_v3.4634,764,242 - 34,764,423UniSTSRGSC3.4
Celera633,433,285 - 33,433,466UniSTS
RH 3.4 Map6143.8UniSTS
Cytogenetic Map6q14UniSTS
AA850777  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2634,031,404 - 34,031,598 (+)MAPPERmRatBN7.2
Rnor_6.0636,994,124 - 36,994,317NCBIRnor6.0
Rnor_5.0646,744,237 - 46,744,430UniSTSRnor5.0
RGSC_v3.4634,762,817 - 34,763,010UniSTSRGSC3.4
Celera633,431,860 - 33,432,053UniSTS
RH 3.4 Map6144.5UniSTS
Cytogenetic Map6q14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 57 41 19 41 8 10 74 35 41 11 8
Low 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007073   ⟹   ENSRNOP00000007073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl633,978,716 - 34,031,739 (+)Ensembl
Rnor_6.0 Ensembl636,941,233 - 36,994,465 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083383   ⟹   ENSRNOP00000070408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl633,978,716 - 34,031,739 (+)Ensembl
Rnor_6.0 Ensembl636,941,596 - 36,995,138 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000110833   ⟹   ENSRNOP00000078251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl633,984,057 - 34,031,746 (+)Ensembl
RefSeq Acc Id: NM_001108014   ⟹   NP_001101484
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,697,845 - 39,750,826 (+)NCBI
mRatBN7.2633,978,766 - 34,031,746 (+)NCBI
Rnor_6.0636,941,233 - 36,994,465 (+)NCBI
Rnor_5.0646,691,346 - 46,746,033 (+)NCBI
RGSC_v3.4634,710,177 - 34,763,158 (+)RGD
Celera633,379,218 - 33,432,201 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239898   ⟹   XP_006239960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,698,222 - 39,752,275 (+)NCBI
mRatBN7.2633,979,143 - 34,031,676 (+)NCBI
Rnor_6.0636,941,659 - 36,995,920 (+)NCBI
Rnor_5.0646,691,346 - 46,746,033 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039112188   ⟹   XP_038968116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,697,810 - 39,752,275 (+)NCBI
mRatBN7.2633,978,730 - 34,031,676 (+)NCBI
RefSeq Acc Id: XM_039112189   ⟹   XP_038968117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,705,838 - 39,752,275 (+)NCBI
mRatBN7.2633,986,772 - 34,031,676 (+)NCBI
RefSeq Acc Id: XM_039112190   ⟹   XP_038968118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,719,241 - 39,752,275 (+)NCBI
mRatBN7.2634,000,158 - 34,033,201 (+)NCBI
RefSeq Acc Id: XM_039112191   ⟹   XP_038968119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8639,716,332 - 39,752,275 (+)NCBI
mRatBN7.2633,999,513 - 34,033,201 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001101484   ⟸   NM_001108014
- UniProtKB: D4AB26 (UniProtKB/TrEMBL),   A6HAP6 (UniProtKB/TrEMBL),   A0A0G2JXU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239960   ⟸   XM_006239898
- Peptide Label: isoform X1
- UniProtKB: D4AB26 (UniProtKB/TrEMBL),   A6HAP6 (UniProtKB/TrEMBL),   A0A0G2JXU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070408   ⟸   ENSRNOT00000083383
RefSeq Acc Id: ENSRNOP00000007073   ⟸   ENSRNOT00000007073
RefSeq Acc Id: XP_038968116   ⟸   XM_039112188
- Peptide Label: isoform X1
- UniProtKB: D4AB26 (UniProtKB/TrEMBL),   A6HAP6 (UniProtKB/TrEMBL),   A0A0G2JXU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968117   ⟸   XM_039112189
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXU6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968119   ⟸   XM_039112191
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038968118   ⟸   XM_039112190
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000078251   ⟸   ENSRNOT00000110833
Protein Domains
Rad50/SbcC-type AAA   RecF/RecN/SMC N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AB26-F1-model_v2 AlphaFold D4AB26 1-1097 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694494
Promoter ID:EPDNEW_R5019
Type:initiation region
Name:Smc6_1
Description:structural maintenance of chromosomes 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0636,941,218 - 36,941,278EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311214 AgrOrtholog
BioCyc Gene G2FUF-38143 BioCyc
Ensembl Genes ENSRNOG00000004908 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007073 ENTREZGENE
  ENSRNOT00000007073.6 UniProtKB/TrEMBL
  ENSRNOT00000083383.2 UniProtKB/TrEMBL
  ENSRNOT00000110833.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rad50/SbcC_AAA UniProtKB/TrEMBL
  RecF/RecN/SMC_N UniProtKB/TrEMBL
KEGG Report rno:313961 UniProtKB/TrEMBL
NCBI Gene 313961 ENTREZGENE
PANTHER STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 UniProtKB/TrEMBL
  STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 UniProtKB/TrEMBL
Pfam AAA_23 UniProtKB/TrEMBL
  SMC_N UniProtKB/TrEMBL
PhenoGen Smc6 PhenoGen
RatGTEx ENSRNOG00000004908 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2JXU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZKI2_RAT UniProtKB/TrEMBL
  A6HAP6 ENTREZGENE, UniProtKB/TrEMBL
  D4AB26 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Smc6  structural maintenance of chromosomes 6  Smc6l1  SMC6 structural maintenance of chromosomes 6-like 1 (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Smc6l1  SMC6 structural maintenance of chromosomes 6-like 1 (yeast)   Smc6l1_predicted  SMC6 structural maintenance of chromosomes 6-like 1 (yeast) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Smc6l1_predicted  SMC6 structural maintenance of chromosomes 6-like 1 (yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED