Col10a1 (collagen type X alpha 1 chain) - Rat Genome Database

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Gene: Col10a1 (collagen type X alpha 1 chain) Rattus norvegicus
Analyze
Symbol: Col10a1
Name: collagen type X alpha 1 chain
RGD ID: 2371
Description: Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in cartilage development and endochondral ossification. Predicted to be located in cell cortex. Predicted to be part of collagen type X trimer. Predicted to be active in extracellular matrix. Biomarker of degenerative disc disease. Human ortholog(s) of this gene implicated in Schmid metaphyseal chondrodysplasia and osteochondrodysplasia. Orthologous to human COL10A1 (collagen type X alpha 1 chain); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: collagen alpha-1(X) chain; Collagen type X alpha 1; collagen, type X, alpha 1; procollagen, type X, alpha 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82039,737,536 - 39,744,518 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2039,716,822 - 39,751,440 (+)EnsemblGRCr8
mRatBN7.22038,183,103 - 38,189,488 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2038,182,494 - 38,189,494 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd2039,731,950 - 39,738,930 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive2040,798,473 - 40,805,453 (+)NCBILyon_Normotensive
Lyon_Hypertensive2040,861,337 - 40,868,317 (+)NCBILyon_Hypertensive
F344_StmMcwi2039,682,910 - 39,689,890 (+)NCBIF344_StmMcwi
Rnor_6.02041,180,295 - 41,190,664 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2041,184,287 - 41,189,633 (+)Ensemblrn6Rnor6.0
Rnor_5.02042,909,408 - 42,919,566 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42038,725,164 - 38,731,513 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2038,959,927 - 38,970,291 (+)NCBICelera
RGSC_v3.12038,752,633 - 38,754,523 (+)NCBI
RH 3.4 Map20408.35RGD
Cytogenetic Map20q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-phenylbutyric acid  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
acrylamide  (EXP)
alginic acid  (ISO)
all-trans-retinoic acid  (EXP,ISO)
aluminium oxide  (ISO)
ammonium chloride  (EXP)
benzo[a]pyrene  (ISO)
berberine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C60 fullerene  (EXP)
celecoxib  (ISO)
ciglitazone  (EXP)
cycloheximide  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP)
fenvalerate  (EXP)
fulvestrant  (ISO)
gentamycin  (EXP)
kaempferol  (ISO)
L-ascorbic acid  (ISO)
linalool  (EXP)
lipopolysaccharide  (ISO)
methamphetamine  (EXP)
methylparaben  (ISO)
Mofezolac (TN)  (ISO)
montelukast  (ISO)
NS-398  (ISO)
Octicizer  (ISO)
okadaic acid  (ISO)
prostaglandin E2  (ISO)
prostaglandin F2alpha  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sirtinol  (ISO)
T-2 toxin  (ISO)
thromboxane A2  (ISO)
tributyl phosphate  (ISO)
triphenyl phosphate  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tris(2-chloroethyl) phosphate  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
zileuton  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Early cartilage degeneration in a rat experimental model of developmental dysplasia of the hip. Bo N, etal., Connect Tissue Res. 2012;53(6):513-20. doi: 10.3109/03008207.2012.700346. Epub 2012 Jul 20.
2. Modulated expression of type X collagen in Meckel's cartilage with different developmental fates. Chung KS, etal., Dev Biol 1995 Aug;170(2):387-96.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
6. Prolonged upright posture induces degenerative changes in intervertebral discs of rat cervical spine. Liang QQ, etal., Spine (Phila Pa 1976). 2011 Jan 1;36(1):E14-9. doi: 10.1097/BRS.0b013e3181d2dec2.
7. Upregulated Collagen COL10A1 Remodels the Extracellular Matrix and Promotes Malignant Progression in Lung Adenocarcinoma. Liang Y, etal., Front Oncol. 2020 Nov 26;10:573534. doi: 10.3389/fonc.2020.573534. eCollection 2020.
8. Endochondral bone formation in toothless (osteopetrotic) rats: failures of chondrocyte patterning and type X collagen expression. Marks SC Jr, etal., Int J Dev Biol 2000 Apr;44(3):309-16.
9. Additional mutations of type X collagen confirm COL10A1 as the Schmid metaphyseal chondrodysplasia locus. McIntosh I, etal., Hum Mol Genet. 1994 Feb;3(2):303-7.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
12. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. GOA pipeline RGD automated data pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9008714   PMID:9449075   PMID:18849019   PMID:20591638   PMID:20812917   PMID:22206015  


Genomics

Comparative Map Data
Col10a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82039,737,536 - 39,744,518 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2039,716,822 - 39,751,440 (+)EnsemblGRCr8
mRatBN7.22038,183,103 - 38,189,488 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2038,182,494 - 38,189,494 (+)EnsemblmRatBN7.2
Dahl_SR_JrHsd2039,731,950 - 39,738,930 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive2040,798,473 - 40,805,453 (+)NCBILyon_Normotensive
Lyon_Hypertensive2040,861,337 - 40,868,317 (+)NCBILyon_Hypertensive
F344_StmMcwi2039,682,910 - 39,689,890 (+)NCBIF344_StmMcwi
Rnor_6.02041,180,295 - 41,190,664 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2041,184,287 - 41,189,633 (+)Ensemblrn6Rnor6.0
Rnor_5.02042,909,408 - 42,919,566 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42038,725,164 - 38,731,513 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2038,959,927 - 38,970,291 (+)NCBICelera
RGSC_v3.12038,752,633 - 38,754,523 (+)NCBI
RH 3.4 Map20408.35RGD
Cytogenetic Map20q12NCBI
COL10A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386116,118,909 - 116,217,144 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6116,118,909 - 116,158,747 (-)Ensemblhg38GRCh38
GRCh376116,440,072 - 116,538,307 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366116,546,778 - 116,553,989 (-)NCBIBuild 36Build 36hg18NCBI36
Build 346116,546,813 - 116,553,989NCBI
Celera6117,183,107 - 117,190,321 (-)NCBICelera
Cytogenetic Map6q22.1NCBI
HuRef6114,020,279 - 114,027,493 (-)NCBIHuRef
CHM1_16116,703,904 - 116,711,118 (-)NCBICHM1_1
T2T-CHM13v2.06117,302,889 - 117,401,128 (-)NCBIT2T-CHM13v2.0
Col10a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391034,265,977 - 34,273,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1034,265,977 - 34,273,081 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381034,389,981 - 34,397,085 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1034,389,981 - 34,397,085 (+)Ensemblmm10GRCm38
MGSCv371034,109,787 - 34,116,891 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361034,079,251 - 34,087,720 (+)NCBIMGSCv36mm8
Celera1035,298,560 - 35,305,664 (+)NCBICelera
Cytogenetic Map10B1NCBI
cM Map1018.85NCBI
Col10a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955526641,577 - 679,295 (+)Ensembl
ChiLan1.0NW_004955526641,577 - 679,295 (+)NCBIChiLan1.0ChiLan1.0
COL10A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25136,127,283 - 136,174,508 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16134,020,364 - 134,026,855 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06113,921,538 - 113,961,490 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16118,067,477 - 118,074,684 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6118,067,477 - 118,074,684 (-)EnsemblpanPan2panpan1.1
COL10A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11271,803,372 - 71,810,049 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1271,798,692 - 71,809,399 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1271,564,697 - 71,571,376 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01272,686,150 - 72,692,813 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1272,686,480 - 72,692,182 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11272,038,103 - 72,044,761 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01271,879,881 - 71,886,556 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01272,268,767 - 72,275,438 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Col10a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946107,009,485 - 107,017,306 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936824734,488 - 769,010 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936824734,499 - 741,674 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
COL10A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl181,765,859 - 81,773,818 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1181,766,829 - 81,773,818 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2191,881,410 - 91,889,388 (-)NCBISscrofa10.2Sscrofa10.2susScr3
COL10A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11357,657,310 - 57,697,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1357,691,409 - 57,696,783 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604029,980,950 - 30,021,212 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Col10a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248562,335,986 - 2,372,848 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248562,366,524 - 2,372,928 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Col10a1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11836,024,866 - 36,030,519 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Col10a1
45 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:29
Count of miRNA genes:27
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000000655
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202668936256021148Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202679235356021148Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)201224324249189476Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202668936256021148Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)202074558556021148Rat
1598869Memor6Memory QTL 63.1exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)202668936256021148Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
70158Bp60Blood pressure QTL 603arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)203215696745978663Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202668936256021148Rat

Markers in Region
RH94871  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22038,188,033 - 38,188,329 (+)MAPPERmRatBN7.2
Rnor_6.02041,189,210 - 41,189,505NCBIRnor6.0
Rnor_5.02042,918,112 - 42,918,407UniSTSRnor5.0
RGSC_v3.42038,730,059 - 38,730,354UniSTSRGSC3.4
Celera2038,968,837 - 38,969,132UniSTS
RH 3.4 Map20408.35UniSTS
Cytogenetic Map20q12UniSTS
RH139629  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22038,189,069 - 38,189,249 (+)MAPPERmRatBN7.2
Rnor_6.02041,190,246 - 41,190,425NCBIRnor6.0
Rnor_5.02042,919,148 - 42,919,327UniSTSRnor5.0
RGSC_v3.42038,731,095 - 38,731,274UniSTSRGSC3.4
Celera2038,969,873 - 38,970,052UniSTS
RH 3.4 Map20407.04UniSTS
Cytogenetic Map20q12UniSTS
Col10a1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22038,188,024 - 38,188,449 (+)MAPPERmRatBN7.2
Rnor_6.02041,189,201 - 41,189,625NCBIRnor6.0
Rnor_5.02042,918,103 - 42,918,527UniSTSRnor5.0
RGSC_v3.42038,730,050 - 38,730,474UniSTSRGSC3.4
Celera2038,968,828 - 38,969,252UniSTS
Cytogenetic Map20q12UniSTS
Col10a1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22038,187,548 - 38,188,135 (+)MAPPERmRatBN7.2
Rnor_6.02041,188,725 - 41,189,311NCBIRnor6.0
Rnor_5.02042,917,812 - 42,918,213UniSTSRnor5.0
RGSC_v3.42038,729,602 - 38,730,160UniSTSRGSC3.4
Celera2038,968,357 - 38,968,938UniSTS
Cytogenetic Map20q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
14 11 30 130 51 50 19 87 19 5 241 146 11 110 54 76 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000081117   ⟹   ENSRNOP00000074127
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2039,737,536 - 39,744,518 (+)Ensembl
mRatBN7.2 Ensembl2038,182,494 - 38,189,494 (+)Ensembl
Rnor_6.0 Ensembl2041,184,287 - 41,189,633 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158262   ⟹   ENSRNOP00000100349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2039,716,822 - 39,751,440 (+)Ensembl
RefSeq Acc Id: NM_013140   ⟹   NP_037272
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82039,737,536 - 39,744,518 (+)NCBI
Dahl_SR_JrHsd2039,731,950 - 39,738,930 (+)NCBI
Lyon_Normotensive2040,798,473 - 40,805,453 (+)NCBI
Lyon_Hypertensive2040,861,337 - 40,868,317 (+)NCBI
F344_StmMcwi2039,682,910 - 39,689,890 (+)NCBI
Protein Sequences
Protein RefSeqs NP_037272 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB35102 (Get FASTA)   NCBI Sequence Viewer  
  CAA10518 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074127
  ENSRNOP00000074127.1
  ENSRNOP00000100349.1
Ensembl Acc Id: ENSRNOP00000074127   ⟸   ENSRNOT00000081117
RefSeq Acc Id: NP_037272   ⟸   NM_013140
- Peptide Label: precursor
- UniProtKB: A0A0G2K7A5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000100349   ⟸   ENSRNOT00000158262
Protein Domains
C1q

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7A5-F1-model_v2 AlphaFold A0A0G2K7A5 1-680 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2371 AgrOrtholog
BioCyc Gene G2FUF-3550 BioCyc
Ensembl Genes ENSRNOG00000051399 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081117 ENTREZGENE
  ENSRNOT00000081117.3 UniProtKB/TrEMBL
  ENSRNOT00000158262.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.40 UniProtKB/TrEMBL
InterPro C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
  Collagen/C1q_domain UniProtKB/TrEMBL
  Tumour_necrosis_fac-like UniProtKB/TrEMBL
NCBI Gene 25681 ENTREZGENE
PANTHER COMPLEMENT C1Q TUMOR NECROSIS FACTOR-RELATED PROTEIN 2-LIKE UniProtKB/TrEMBL
  EMI DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER UniProtKB/TrEMBL
Pfam C1q UniProtKB/TrEMBL
  Collagen UniProtKB/TrEMBL
PhenoGen Col10a1 PhenoGen
PRINTS COMPLEMNTC1Q UniProtKB/TrEMBL
PROSITE C1Q UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051399 RatGTEx
SMART C1Q UniProtKB/TrEMBL
Superfamily-SCOP TNF_like UniProtKB/TrEMBL
UniProt A0A0G2K7A5 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0KYU7_RAT UniProtKB/TrEMBL
  Q9Z1K4_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Col10a1  collagen type X alpha 1 chain  Col10a1  collagen, type X, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Col10a1  collagen, type X, alpha 1  Col10a1  procollagen, type X, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-11-06 Col10a1  procollagen, type X, alpha 1    Collagen type X alpha 1  Name updated 625702 APPROVED
2002-06-10 Col10a1  Collagen type X alpha 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization extracellular matrix collagen protein 1298775
gene_process may regulate fibrous transformation and endochondral ossification in Meckel's cartilage during development 1298775