Tirap (TIR domain containing adaptor protein) - Rat Genome Database

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Gene: Tirap (TIR domain containing adaptor protein) Rattus norvegicus
Analyze
Symbol: Tirap
Name: TIR domain containing adaptor protein
RGD ID: 1595496
Description: Predicted to enable several functions, including Toll-like receptor binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and protein kinase C binding activity. Predicted to be involved in several processes, including TIRAP-dependent toll-like receptor 4 signaling pathway; positive regulation of gene expression; and positive regulation of signal transduction. Predicted to act upstream of or within several processes, including myeloid cell differentiation; positive regulation of macrophage cytokine production; and response to bacterium. Predicted to be located in endocytic vesicle and ruffle membrane. Predicted to be active in cell surface; cytoplasm; and plasma membrane. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in malaria and tuberculosis. Orthologous to human TIRAP (TIR domain containing adaptor protein); PARTICIPATES IN Toll-like receptor signaling pathway; tuberculosis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC680127; similar to Toll-interleukin 1 receptor domain-containing adaptor protein; toll-interleukin 1 receptor (TIR) domain-containing adaptor protein; toll/interleukin-1 receptor domain-containing adapter protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,789,557 - 41,805,903 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl841,791,878 - 41,796,312 (-)EnsemblGRCr8
mRatBN7.2833,531,724 - 33,548,508 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,531,725 - 33,547,432 (-)EnsemblmRatBN7.2
Rnor_6.0836,382,029 - 36,399,625 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,385,353 - 36,388,224 (-)Ensemblrn6Rnor6.0
Rnor_5.0836,400,673 - 36,406,908 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4834,966,856 - 34,969,727 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera834,950,692 - 34,968,852 (-)NCBICelera
Cytogenetic Map8q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
3'-UTR-mediated mRNA stabilization  (ISO)
biological_process  (ND)
cell surface receptor signaling pathway  (ISO)
cellular response to bacterial lipopeptide  (ISO)
cellular response to lipoteichoic acid  (ISO)
defense response to Gram-positive bacterium  (ISO)
immune system process  (IEA)
inflammatory response  (IEA)
innate immune response  (IEA)
interleukin-1-mediated signaling pathway  (ISO)
myeloid cell differentiation  (ISO)
positive regulation of B cell proliferation  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (IBA,ISO)
positive regulation of chemokine (C-X-C motif) ligand 1 production  (ISO)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (IBA,ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of innate immune response  (ISO)
positive regulation of interleukin-12 production  (ISO)
positive regulation of interleukin-15 production  (ISO)
positive regulation of interleukin-6 production  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of neutrophil chemotaxis  (ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of toll-like receptor 2 signaling pathway  (ISO)
positive regulation of toll-like receptor 3 signaling pathway  (ISO)
positive regulation of toll-like receptor 4 signaling pathway  (ISO)
positive regulation of tumor necrosis factor production  (IBA,ISO)
regulation of innate immune response  (IEA)
regulation of interferon-beta production  (ISO)
regulation of interleukin-15 production  (ISO)
response to lipopolysaccharide  (ISO)
signal transduction  (IEA)
TIRAP-dependent toll-like receptor 4 signaling pathway  (ISO)
toll-like receptor 4 signaling pathway  (IBA,ISO)
toll-like receptor 5 signaling pathway  (ISO)
toll-like receptor TLR1:TLR2 signaling pathway  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11526399   PMID:11544529   PMID:12062447   PMID:12421970   PMID:12447442   PMID:14630816   PMID:15294994   PMID:15690042   PMID:16301656   PMID:16751103   PMID:17161867   PMID:17258210  
PMID:17322885   PMID:18039275   PMID:18583567   PMID:19509286   PMID:19948740   PMID:20451243   PMID:24275656  


Genomics

Comparative Map Data
Tirap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8841,789,557 - 41,805,903 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl841,791,878 - 41,796,312 (-)EnsemblGRCr8
mRatBN7.2833,531,724 - 33,548,508 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl833,531,725 - 33,547,432 (-)EnsemblmRatBN7.2
Rnor_6.0836,382,029 - 36,399,625 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl836,385,353 - 36,388,224 (-)Ensemblrn6Rnor6.0
Rnor_5.0836,400,673 - 36,406,908 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4834,966,856 - 34,969,727 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera834,950,692 - 34,968,852 (-)NCBICelera
Cytogenetic Map8q21NCBI
TIRAP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811126,283,093 - 126,294,933 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11126,282,497 - 126,298,845 (+)Ensemblhg38GRCh38
GRCh3711126,152,988 - 126,164,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611125,658,192 - 125,670,038 (+)NCBIBuild 36Build 36hg18NCBI36
Celera11123,318,165 - 123,330,030 (+)NCBICelera
Cytogenetic Map11q24.2NCBI
HuRef11122,098,046 - 122,109,916 (+)NCBIHuRef
CHM1_111126,039,258 - 126,051,104 (+)NCBICHM1_1
T2T-CHM13v2.011126,314,493 - 126,326,362 (+)NCBIT2T-CHM13v2.0
Tirap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39935,095,687 - 35,111,587 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl935,095,847 - 35,111,587 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38935,184,391 - 35,200,291 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl935,184,551 - 35,200,291 (-)Ensemblmm10GRCm38
MGSCv37934,991,976 - 35,007,876 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36934,936,435 - 34,949,545 (-)NCBIMGSCv36mm8
Celera932,421,410 - 32,437,270 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map919.99NCBI
Tirap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541227,312,489 - 27,315,031 (+)Ensembl
ChiLan1.0NW_00495541227,303,548 - 27,315,031 (+)NCBIChiLan1.0ChiLan1.0
TIRAP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29126,969,695 - 126,984,474 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111128,077,374 - 128,092,151 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011121,100,558 - 121,112,844 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111125,018,064 - 125,022,309 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11125,018,064 - 125,022,309 (+)EnsemblpanPan2panpan1.1
TIRAP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.158,222,217 - 8,237,595 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl58,221,794 - 8,226,074 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha58,275,792 - 8,300,808 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.058,170,182 - 8,195,206 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl58,176,896 - 8,181,685 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.158,239,756 - 8,264,804 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.058,213,520 - 8,238,550 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.058,247,729 - 8,272,742 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tirap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947108,511,610 - 108,526,005 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365725,924,158 - 5,938,658 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365725,926,193 - 5,938,621 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TIRAP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl953,375,644 - 53,394,165 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1953,374,559 - 53,394,172 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2959,036,463 - 59,057,589 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TIRAP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11117,417,561 - 117,419,870 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660438,650,207 - 8,662,061 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tirap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624812439,319 - 446,646 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_004624812433,540 - 445,517 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tirap
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1830,737,901 - 30,751,077 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tirap
123 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:117
Count of miRNA genes:97
Interacting mature miRNAs:103
Transcripts:ENSRNOT00000038312
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
61337Bp22Blood pressure QTL 225.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625851589833Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83776085958991895Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83776085961459705Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625867378345Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
70206Alc20Alcohol consumption QTL 202drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)83910625849610361Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
23 13 84 211 91 90 59 157 59 6 483 284 22 189 109 124 31 34 34

Sequence


Ensembl Acc Id: ENSRNOT00000038312   ⟹   ENSRNOP00000032025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl841,791,878 - 41,796,312 (-)Ensembl
mRatBN7.2 Ensembl833,531,725 - 33,547,432 (-)Ensembl
Rnor_6.0 Ensembl836,385,353 - 36,388,224 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128067   ⟹   ENSRNOP00000111997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl841,792,304 - 41,796,312 (-)Ensembl
RefSeq Acc Id: XM_017596003   ⟹   XP_017451492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,789,557 - 41,798,085 (-)NCBI
mRatBN7.2833,531,724 - 33,548,102 (-)NCBI
Rnor_6.0836,384,090 - 36,398,401 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001839296
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8841,789,557 - 41,805,903 (-)NCBI
mRatBN7.2833,531,724 - 33,548,102 (-)NCBI
Rnor_6.0836,382,029 - 36,398,401 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001417315 (Get FASTA)   NCBI Sequence Viewer  
  NP_001417316 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451492 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL83279 (Get FASTA)   NCBI Sequence Viewer  
  EDL83280 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000032025
  ENSRNOP00000032025.5
  ENSRNOP00000111997.1
RefSeq Acc Id: XP_017451492   ⟸   XM_017596003
- UniProtKB: D3ZXA5 (UniProtKB/TrEMBL),   A6JYJ6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032025   ⟸   ENSRNOT00000038312
Ensembl Acc Id: ENSRNOP00000111997   ⟸   ENSRNOT00000128067
Protein Domains
TIR

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZXA5-F1-model_v2 AlphaFold D3ZXA5 1-250 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1595496 AgrOrtholog
BioCyc Gene G2FUF-31192 BioCyc
Ensembl Genes ENSRNOG00000021420 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038312 ENTREZGENE
  ENSRNOT00000038312.7 UniProtKB/TrEMBL
  ENSRNOT00000128067.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.10140 UniProtKB/TrEMBL
InterPro Tol-interleuk_rcpt_adapt_Tirap UniProtKB/TrEMBL
  Toll-Interleukin_rcpt UniProtKB/TrEMBL
  Toll_tir_struct_dom_sf UniProtKB/TrEMBL
KEGG Report rno:680127 UniProtKB/TrEMBL
NCBI Gene 680127 ENTREZGENE
PANTHER PTHR22662 UniProtKB/TrEMBL
  TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN UniProtKB/TrEMBL
Pfam TIR_2 UniProtKB/TrEMBL
PhenoGen Tirap PhenoGen
PIRSF TIR_Tirap UniProtKB/TrEMBL
PROSITE TIR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021420 RatGTEx
Superfamily-SCOP TIR UniProtKB/TrEMBL
UniProt A0ABK0M8H9_RAT UniProtKB/TrEMBL
  A6JYJ6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZXA5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-22 Tirap  TIR domain containing adaptor protein  Tirap  toll-interleukin 1 receptor (TIR) domain-containing adaptor protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Tirap  toll-interleukin 1 receptor (TIR) domain-containing adaptor protein  LOC680127  similar to Toll-interleukin 1 receptor domain-containing adaptor protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC680127  similar to Toll-interleukin 1 receptor domain-containing adaptor protein  LOC681662  similar to Toll-interleukin 1 receptor domain-containing adaptor protein  Data merged from RGD:1592875 1643240 APPROVED
2006-11-20 LOC680127  similar to Toll-interleukin 1 receptor domain-containing adaptor protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC681662  similar to Toll-interleukin 1 receptor domain-containing adaptor protein      Symbol and Name status set to provisional 70820 PROVISIONAL