Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein)

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Keyword

Gene: Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein) Mus musculus

Symbol:

Tirap

Name:

toll-interleukin 1 receptor (TIR) domain-containing adaptor protein

Description:

ENCODES a protein that exhibits phosphatidylinositol-4,5-bisphosphate binding; protein heterodimerization activity; protein homodimerization activity; INVOLVED IN cell surface receptor signaling pathway; cellular response to bacterial lipopeptide; cellular response to lipoteichoic acid; PARTICIPATES IN Toll-like receptor signaling pathway; Mycobacterium tuberculosis infection pathway; ASSOCIATED WITH abnormal cytokine secretion; abnormal dendritic cell physiology; abnormal level of surface class II molecules; ASSOCIATED WITH Invasive Pneumococcal Disease, Recurrent Isolated, 1 (ortholog); Malaria (ortholog); MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (ortholog); FOUND IN endocytic vesicle; ruffle membrane; cytoplasm (ortholog); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

AA407980; adaptor protein Wyatt; C130027E04Rik; Mal; myD88 adapter-like protein; MyD88-adapter-like; TIR domain-containing adapter protein; Tlr4ap; Toll-like receptor 4 adaptor protein; toll/interleukin-1 receptor domain-containing adapter protein; wyatt; Wyatt

Orthologs:

Homo sapiens : TIRAP (toll-interleukin 1 receptor (TIR) domain containing adaptor protein) HGNC
Rattus norvegicus : Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	9	35,184,391 - 35,200,291	-	NCBI
Mouse cM Map	9		-	NCBI
Mouse Celera Assembly	9	32,421,410 - 32,437,270	-	NCBI
Mouse Genome Assembly Build 37	9	34,991,976 - 35,007,876	-	NCBI
Mouse Genome Assembly Build 36.1	9	34,994,349 - 35,007,459	-	NCBI
Mouse Cytogenetic Map	9	A5.3		NCBI