Or2w1 (olfactory receptor family 2 subfamily W member 1) - Rat Genome Database

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Gene: Or2w1 (olfactory receptor family 2 subfamily W member 1) Rattus norvegicus
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Symbol: Or2w1
Name: olfactory receptor family 2 subfamily W member 1
RGD ID: 1334041
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human OR2W1 (olfactory receptor family 2 subfamily W member 1); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: LOC498756; olfactory receptor 1662; olfactory receptor gene Olr1662; olfactory receptor Olr1662; Olr1662; RGD1565918; similar to olfactory receptor Olfr42
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,307,699 - 48,308,652 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1748,307,699 - 48,308,652 (-)EnsemblGRCr8
mRatBN7.21743,611,986 - 43,612,939 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,608,678 - 43,616,084 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1745,676,096 - 45,677,049 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01750,435,196 - 50,436,149 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01744,919,245 - 44,920,198 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01745,687,105 - 45,688,058 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,687,105 - 45,688,058 (-)Ensemblrn6Rnor6.0
Rnor_5.01757,783,016 - 57,783,969 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41751,305,751 - 51,306,704 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1752,866,364 - 52,867,317 (+)NCBICelera
RGSC_v3.11751,308,591 - 51,309,545 (-)NCBI
Cytogenetic Map17q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or2w1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81748,307,699 - 48,308,652 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1748,307,699 - 48,308,652 (-)EnsemblGRCr8
mRatBN7.21743,611,986 - 43,612,939 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1743,608,678 - 43,616,084 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1745,676,096 - 45,677,049 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01750,435,196 - 50,436,149 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01744,919,245 - 44,920,198 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01745,687,105 - 45,688,058 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1745,687,105 - 45,688,058 (-)Ensemblrn6Rnor6.0
Rnor_5.01757,783,016 - 57,783,969 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41751,305,751 - 51,306,704 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1752,866,364 - 52,867,317 (+)NCBICelera
RGSC_v3.11751,308,591 - 51,309,545 (-)NCBI
Cytogenetic Map17q11NCBI
OR2W1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38629,044,213 - 29,045,175 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl629,044,213 - 29,045,175 (-)Ensemblhg38GRCh38
GRCh37629,011,990 - 29,012,952 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36629,119,969 - 29,120,951 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34629,119,968 - 29,120,951NCBI
Celera630,618,100 - 30,619,062 (-)NCBICelera
Cytogenetic Map6p22.1NCBI
HuRef628,819,393 - 28,820,355 (-)NCBIHuRef
CHM1_1629,014,283 - 29,015,245 (-)NCBICHM1_1
T2T-CHM13v2.0628,918,914 - 28,919,876 (-)NCBIT2T-CHM13v2.0
Or2w1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391321,316,947 - 21,317,900 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1321,313,809 - 21,320,466 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381321,132,777 - 21,133,730 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1321,129,639 - 21,136,296 (+)Ensemblmm10GRCm38
MGSCv371321,224,646 - 21,225,599 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361321,140,242 - 21,141,195 (+)NCBIMGSCv36mm8
Celera1321,397,837 - 21,398,790 (+)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map137.65NCBI

Variants

.
Variants in Or2w1
4 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000059275
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552966Pigfal18Plasma insulin-like growth factor 1 level QTL 188.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)171286094257860942Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172266079955604694Rat
9589151Insul30Insulin level QTL 308.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)171286094257860942Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172149899450592236Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
1600398Edcs5Endometrial carcinoma susceptibility QTL 52.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)173544694975762341Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
9590154Scort9Serum corticosterone level QTL 923.570.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)171286094257860942Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171553702560531414Rat
7411666Foco31Food consumption QTL 3111.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)171286094257860942Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172723344565155015Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172385892668858926Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
70210Cm15Cardiac mass QTL 156.5heart right ventricle mass (VT:0007033)heart right ventricle wet weight (CMO:0000072)173006647275066472Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)173310464578104645Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173219953449497050Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172328632264246472Rat
9589057Scfw6Subcutaneous fat weight QTL 68.620.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)171286094257860942Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)172652205171522051Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172201970567019705Rat
9590088Insglur7Insulin/glucose ratio QTL 720.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)171286094257860942Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173219953455604694Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)171060469455604694Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)173310464578104645Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172385892668858926Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172723344572233445Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172385892668858926Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172385892668858926Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172385892668858926Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172385892668858926Rat


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
2 1 1 20 1 2 19 11

Sequence


Ensembl Acc Id: ENSRNOT00000086807   ⟹   ENSRNOP00000072409
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1745,687,105 - 45,688,058 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111636   ⟹   ENSRNOP00000081637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1743,608,678 - 43,616,084 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159417   ⟹   ENSRNOP00000103301
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1748,307,699 - 48,308,652 (-)Ensembl
RefSeq Acc Id: NM_001000107   ⟹   NP_001000107
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81748,307,699 - 48,308,652 (-)NCBI
mRatBN7.21743,611,986 - 43,612,939 (-)NCBI
Rnor_6.01745,687,105 - 45,688,058 (-)NCBI
Rnor_5.01757,783,016 - 57,783,969 (+)NCBI
RGSC_v3.41751,305,751 - 51,306,704 (-)RGD
Celera1752,866,364 - 52,867,317 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001000107 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL84530 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000103301
  ENSRNOP00000103301.1
RefSeq Acc Id: NP_001000107   ⟸   NM_001000107
- UniProtKB: A0A8I5ZU47 (UniProtKB/TrEMBL),   A6KN62 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000072409   ⟸   ENSRNOT00000086807
Ensembl Acc Id: ENSRNOP00000081637   ⟸   ENSRNOT00000111636
Ensembl Acc Id: ENSRNOP00000103301   ⟸   ENSRNOT00000159417
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2X0-F1-model_v2 AlphaFold A0A0G2K2X0 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1334041 AgrOrtholog
BioCyc Gene G2FUF-9169 BioCyc
Ensembl Genes ENSRNOG00000061218 Ensembl
  ENSRNOG00000066799 Ensembl
  ENSRNOG00000073548 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000159417 ENTREZGENE
  ENSRNOT00000159417.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:291361 UniProtKB/TrEMBL
NCBI Gene 291361 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or2w1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061218 RatGTEx
  ENSRNOG00000066799 RatGTEx
  ENSRNOG00000073548 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8I5ZU47 ENTREZGENE
  A0ABK0LQ74_RAT UniProtKB/TrEMBL
  A6KN62 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or2w1  olfactory receptor family 2 subfamily W member 1  Olr1662  olfactory receptor 1662  Symbol and Name Changed 1299863 APPROVED
2015-07-29 Olr1662  olfactory receptor 1662  RGD1565918  similar to olfactory receptor Olfr42  Data merged from RGD:1565918 737654 PROVISIONAL
2013-05-24 Olr1662  olfactory receptor 1662  LOC682056  similar to olfactory receptor 42  Data merged from RGD:1588111 1643240 APPROVED
2008-04-30 RGD1565918  similar to olfactory receptor Olfr42   RGD1565918_predicted  similar to olfactory receptor Olfr42 (predicted)  'predicted' is removed 2292626 APPROVED
2008-04-30 Olr1662  olfactory receptor 1662   Olr1662_predicted  olfactory receptor 1662 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC682056  similar to olfactory receptor 42      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1565918_predicted  similar to olfactory receptor Olfr42 (predicted)  LOC498756  similar to olfactory receptor Olfr42  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498756  similar to olfactory receptor Olfr42      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-02-04 Olr1662_predicted  olfactory receptor 1662 (predicted)      Symbol and Name status set to approved 70820 APPROVED