Ccl24 (C-C motif chemokine ligand 24) - Rat Genome Database

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Gene: Ccl24 (C-C motif chemokine ligand 24) Rattus norvegicus
Analyze
Symbol: Ccl24
Name: C-C motif chemokine ligand 24
RGD ID: 1310245
Description: Predicted to enable CCR3 chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including eosinophil chemotaxis; positive regulation of actin filament polymerization; and positive regulation of endothelial cell proliferation. Predicted to act upstream of or within chemotaxis and positive regulation of eosinophil migration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in asthma and rhinitis. Orthologous to human CCL24 (C-C motif chemokine ligand 24); PARTICIPATES IN chemokine mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-C motif chemokine 24; chemokine (C-C motif) ligand 24; eosinophil chemotactic protein 2; eotaxin-2; eotaxin-2-like protein; LOC288593
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,737,423 - 26,741,420 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,737,439 - 26,750,924 (+)EnsemblGRCr8
mRatBN7.21221,100,835 - 21,104,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,100,835 - 21,104,893 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1222,242,781 - 22,246,614 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,855,125 - 22,858,958 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,921,589 - 21,925,422 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,131,529 - 24,152,626 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,148,567 - 24,152,625 (+)Ensemblrn6Rnor6.0
Rnor_5.01226,128,835 - 26,149,929 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,255,293 - 22,259,290 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,863,236 - 22,867,233 (+)NCBICelera
RGSC_v3.11222,252,921 - 22,256,286 (+)NCBI
Cytogenetic Map12q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
1-nitropyrene  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
Azoxymethane  (ISO)
barium sulfate  (EXP)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Brevianamide A  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
ceric oxide  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cobalt atom  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diisononyl phthalate  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
genistein  (ISO)
graphene oxide  (ISO)
iron(2+) sulfate (anhydrous)  (ISO)
metformin  (ISO)
methimazole  (EXP)
N-acetyl-L-cysteine  (ISO)
nickel atom  (ISO)
ozone  (ISO)
paraquat  (EXP)
pirinixic acid  (ISO)
propiconazole  (EXP)
Ptaquiloside  (ISO)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
TMC-120A  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (EXP)
valproic acid  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Analysis of the polymorphisms in eotaxin gene family and their association with asthma, IgE, and eosinophil. Chae SC, etal., Biochem Biophys Res Commun. 2004 Jul 16;320(1):131-7.
2. The suggestive association of eotaxin-2 and eotaxin-3 gene polymorphisms in Korean population with allergic rhinitis. Chae SC, etal., Immunogenetics. 2005 Jan;56(10):760-4. Epub 2004 Dec 4.
3. A central regulatory role for eosinophils and the eotaxin/CCR3 axis in chronic experimental allergic airway inflammation. Fulkerson PC, etal., Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16418-23. Epub 2006 Oct 23.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia. Jahnsen FL, etal., J Immunol. 1999 Aug 1;163(3):1545-51.
7. Reductions in circulating levels of IL-16, IL-7 and VEGF-A in myalgic encephalomyelitis/chronic fatigue syndrome. Landi A, etal., Cytokine. 2016 Feb;78:27-36. doi: 10.1016/j.cyto.2015.11.018. Epub 2015 Nov 28.
8. Genetic interactions model among Eotaxin gene polymorphisms in asthma. Lee JH, etal., J Hum Genet. 2008;53(10):867-75. Epub 2008 Aug 20.
9. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
10. Comparison of plasma eotaxin family level in aspirin-induced and aspirin-tolerant asthma patients. Min JW, etal., Chest. 2005 Nov;128(5):3127-32.
11. Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma. Ochkur SI, etal., J Immunol. 2007 Jun 15;178(12):7879-89.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. GOA pipeline RGD automated data pipeline
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Role of the chemokines RANTES, monocyte chemotactic proteins-3 and -4, and eotaxins-1 and -2 in childhood asthma. Rojas-Ramos E, etal., Eur Respir J. 2003 Aug;22(2):310-6.
17. Association of Eotaxin gene family with asthma and serum total IgE. Shin HD, etal., Hum Mol Genet. 2003 Jun 1;12(11):1279-85.
18. Eotaxin-1, -2, and -3 immunoreactivity and protein concentration in the nasal polyps of eosinophilic chronic rhinosinusitis patients. Yao T, etal., Laryngoscope. 2009 Jun;119(6):1053-9.
19. Complementary DNA microarray analysis of chemokines and their receptors in allergic rhinitis. Zhang RX, etal., J Investig Allergol Clin Immunol. 2007;17(5):329-36.
Additional References at PubMed
PMID:10072545   PMID:11067944   PMID:11425309   PMID:12477932   PMID:15647285   PMID:19525930   PMID:19841166  


Genomics

Comparative Map Data
Ccl24
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81226,737,423 - 26,741,420 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1226,737,439 - 26,750,924 (+)EnsemblGRCr8
mRatBN7.21221,100,835 - 21,104,832 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1221,100,835 - 21,104,893 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1222,242,781 - 22,246,614 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01222,855,125 - 22,858,958 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01221,921,589 - 21,925,422 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,131,529 - 24,152,626 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,148,567 - 24,152,625 (+)Ensemblrn6Rnor6.0
Rnor_5.01226,128,835 - 26,149,929 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,255,293 - 22,259,290 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1222,863,236 - 22,867,233 (+)NCBICelera
RGSC_v3.11222,252,921 - 22,256,286 (+)NCBI
Cytogenetic Map12q12NCBI
CCL24
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38775,810,825 - 75,823,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl775,810,825 - 75,823,943 (-)Ensemblhg38GRCh38
GRCh37775,440,143 - 75,452,690 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,279,050 - 75,280,969 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34775,085,764 - 75,087,684NCBI
Celera770,308,880 - 70,310,799 (-)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef770,527,210 - 70,529,129 (-)NCBIHuRef
CHM1_1775,371,135 - 75,373,054 (-)NCBICHM1_1
T2T-CHM13v2.0777,097,889 - 77,110,477 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2774,774,178 - 74,776,097 (-)NCBI
Ccl24
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,598,789 - 135,601,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5135,598,791 - 135,601,903 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385135,569,935 - 135,573,123 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5135,569,937 - 135,573,049 (-)Ensemblmm10GRCm38
MGSCv375136,045,807 - 136,048,913 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365135,855,239 - 135,857,652 (-)NCBIMGSCv36mm8
Celera5132,581,470 - 132,584,576 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map575.28NCBI
Ccl24
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545614,583,610 - 14,585,169 (-)Ensembl
ChiLan1.0NW_00495545614,582,812 - 14,588,574 (-)NCBIChiLan1.0ChiLan1.0
CCL24
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2694,139,812 - 94,145,048 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17142,404,562 - 142,409,686 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0768,206,688 - 68,210,343 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1782,263,310 - 82,265,480 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl782,263,310 - 82,265,480 (-)EnsemblpanPan2panpan1.1
CCL24
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.167,166,165 - 7,179,606 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl67,166,479 - 7,180,051 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha68,864,028 - 8,865,941 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.066,986,790 - 7,000,238 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl66,987,104 - 7,000,516 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.166,957,433 - 6,959,341 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.066,920,823 - 6,922,728 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.067,084,112 - 7,086,021 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ccl24
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344131,632,998 - 131,635,886 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365432,400,768 - 2,403,217 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365432,400,743 - 2,403,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCL24
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl310,357,524 - 10,361,496 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1310,347,397 - 10,361,500 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CCL24
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12810,067,482 - 10,069,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2810,066,664 - 10,069,695 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660706,366,836 - 6,369,294 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccl24
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474014,640,292 - 14,643,020 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474014,640,486 - 14,652,414 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ccl24
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11618,442,125 - 18,444,347 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ccl24
55 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:134
Count of miRNA genes:110
Interacting mature miRNAs:120
Transcripts:ENSRNOT00000045157
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)122480502252308831Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121120049452308831Rat
2306789Ean6Experimental allergic neuritis QTL 64.9nervous system integrity trait (VT:0010566)experimental autoimmune neuritis severity score (CMO:0001528)12129775522Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122598935552308831Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12348941648489416Rat
1331739Hrtrt14Heart rate QTL 143.56232heart pumping trait (VT:2000009)heart rate (CMO:0000002)12138687564Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121847304152308831Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049752308831Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)121526424852308831Rat
61331Eau2Experimental allergic uveoretinitis QTL 20.0005uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)12133700600Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)121174352852308831Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)121120049452308831Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)12138635130Rat
6893681Bw109Body weight QTL 1092.30.004body mass (VT:0001259)body weight (CMO:0000012)12128133365Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)121223300030490641Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121746497946784661Rat
1300174Bw15Body weight QTL 152.93body mass (VT:0001259)body weight loss (CMO:0001399)12128606299Rat
1331786Kidm11Kidney mass QTL 113.571kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)121618743852308831Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)12133700556Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121613502952308831Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743851213550Rat
1331763Wbc2White blood cell count QTL 23.162leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)121120049452308831Rat
61416Pia4Pristane induced arthritis QTL 48.4joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)121874946936488809Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)61120049452308831Rat
7387292Kidm42Kidney mass QTL 423.030.0004kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)12141361854Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121874946934312613Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12274769447747694Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121847304152308831Rat
2303568Bw88Body weight QTL 883body mass (VT:0001259)body weight (CMO:0000012)12128606299Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12308718048087180Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
7243862Mcs30Mammary carcinoma susceptibility QTL 308.62mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)12563330650633306Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121613502952308831Rat
2293086Iddm30Insulin dependent diabetes mellitus QTL 303.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12790162533938215Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)121120049452308831Rat
11530002Bss119Bone structure and strength QTL 11916.394e-17lumbar vertebra area (VT:0010570)lumbar vertebra area (CMO:0001688)122651003826983303Rat
1331755Bp219Blood pressure QTL 2193.041arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121618743833700556Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
15 12 64 153 91 90 59 48 59 6 304 145 11 130 77 91 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000001963   ⟹   ENSRNOP00000001963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,745,972 - 26,750,924 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000045157   ⟹   ENSRNOP00000056109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,737,439 - 26,741,415 (+)Ensembl
mRatBN7.2 Ensembl1221,100,835 - 21,104,826 (+)Ensembl
Rnor_6.0 Ensembl1224,148,629 - 24,152,620 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077378   ⟹   ENSRNOP00000070658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,737,439 - 26,741,503 (+)Ensembl
mRatBN7.2 Ensembl1221,100,835 - 21,104,893 (+)Ensembl
Rnor_6.0 Ensembl1224,148,567 - 24,152,625 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000146047   ⟹   ENSRNOP00000102984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1226,737,439 - 26,747,698 (+)Ensembl
RefSeq Acc Id: NM_001013045   ⟹   NP_001013063
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81226,737,423 - 26,741,420 (+)NCBI
mRatBN7.21221,100,835 - 21,104,832 (+)NCBI
Rnor_6.01224,148,629 - 24,152,626 (+)NCBI
Rnor_5.01226,128,835 - 26,149,929 (+)NCBI
RGSC_v3.41222,255,293 - 22,259,290 (+)RGD
Celera1222,863,236 - 22,867,233 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001013063 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87576 (Get FASTA)   NCBI Sequence Viewer  
  AAM74022 (Get FASTA)   NCBI Sequence Viewer  
  EDM13365 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001963.5
  ENSRNOP00000056109
  ENSRNOP00000056109.2
  ENSRNOP00000070658.2
  ENSRNOP00000102984.1
RefSeq Acc Id: NP_001013063   ⟸   NM_001013045
- Peptide Label: precursor
- UniProtKB: Q5PPP2 (UniProtKB/TrEMBL),   F6Q1T6 (UniProtKB/TrEMBL),   Q8K477 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000056109   ⟸   ENSRNOT00000045157
Ensembl Acc Id: ENSRNOP00000070658   ⟸   ENSRNOT00000077378
Ensembl Acc Id: ENSRNOP00000001963   ⟸   ENSRNOT00000001963
Ensembl Acc Id: ENSRNOP00000102984   ⟸   ENSRNOT00000146047
Protein Domains
Chemokine interleukin-8-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5PPP2-F1-model_v2 AlphaFold Q5PPP2 1-119 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698558
Promoter ID:EPDNEW_R9075
Type:single initiation site
Name:Ccl24_1
Description:C-C motif chemokine ligand 24
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01224,148,594 - 24,148,654EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310245 AgrOrtholog
BioCyc Gene G2FUF-19626 BioCyc
Ensembl Genes ENSRNOG00000031162 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001963.7 UniProtKB/TrEMBL
  ENSRNOT00000045157 ENTREZGENE
  ENSRNOT00000045157.5 UniProtKB/TrEMBL
  ENSRNOT00000077378.3 UniProtKB/TrEMBL
  ENSRNOT00000146047.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.40 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7307568 IMAGE-MGC_LOAD
InterPro Chemokine_b/g/d UniProtKB/TrEMBL
  Chemokine_IL8 UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/TrEMBL
KEGG Report rno:288593 UniProtKB/TrEMBL
MGC_CLONE MGC:105554 IMAGE-MGC_LOAD
NCBI Gene 288593 ENTREZGENE
PANTHER C-C MOTIF CHEMOKINE 24 UniProtKB/TrEMBL
  C-C MOTIF CHEMOKINE 26 UniProtKB/TrEMBL
  PTHR12015 UniProtKB/TrEMBL
Pfam IL8 UniProtKB/TrEMBL
PhenoGen Ccl24 PhenoGen
RatGTEx ENSRNOG00000031162 RatGTEx
SMART SCY UniProtKB/TrEMBL
Superfamily-SCOP Chemokine_IL8 UniProtKB/TrEMBL
UniProt A0A0G2JYH6_RAT UniProtKB/TrEMBL
  A0ABK0LJ54_RAT UniProtKB/TrEMBL
  D3ZQG2_RAT UniProtKB/TrEMBL
  F6Q1T6 ENTREZGENE, UniProtKB/TrEMBL
  Q5PPP2 ENTREZGENE, UniProtKB/TrEMBL
  Q8K477 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-08 Ccl24  C-C motif chemokine ligand 24  Ccl24  chemokine (C-C motif) ligand 24  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Ccl24  chemokine (C-C motif) ligand 24  Ccl24_predicted  chemokine (C-C motif) ligand 24 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ccl24_predicted  chemokine (C-C motif) ligand 24 (predicted)      Symbol and Name status set to approved 70820 APPROVED