Rdh16 (retinol dehydrogenase 16) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rdh16 (retinol dehydrogenase 16) Rattus norvegicus
Analyze
Symbol: Rdh16
Name: retinol dehydrogenase 16
RGD ID: 735050
Description: Enables all-trans-retinol dehydrogenase (NAD+) activity. Involved in positive regulation of retinoic acid biosynthetic process; retinoic acid metabolic process; and retinol metabolic process. Located in endoplasmic reticulum membrane. Orthologous to human RDH16 (retinol dehydrogenase 16); PARTICIPATES IN retinoic acid metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 29 kDa protein; Rdh2; retinol dehydrogenase 16 (all-trans); retinol dehydrogenase 2; retinol dehydrogenase 2-like; retinol dehydrogenase type 1; retinol dehydrogenase type 2; retinol dehydrogenase type II (RODH II); RODH II; RoDHII
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Candidate Gene For: Bp38
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,499,763 - 65,510,304 (+)NCBIGRCr8
mRatBN7.2763,616,711 - 63,625,053 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,597,536 - 63,624,124 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx765,505,927 - 65,514,269 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,708,217 - 67,716,557 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,509,523 - 67,517,833 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0771,058,150 - 71,072,685 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,980,422 - 71,072,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,151,962 - 71,152,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,752,257 - 67,766,995 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,772,988 - 67,787,725 (+)NCBI
Celera754,092,966 - 54,096,444 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cloning of a cDNA for a second retinol dehydrogenase type II. Expression of its mRNA relative to type I. Chai X, etal., J Biol Chem 1995 Nov 24;270(47):28408-12.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Combined genealogical, mapping, and expression approaches to identify spontaneously hypertensive rat hypertension candidate genes. Hinojos CA, etal., Hypertension 2005 Apr;45(4):698-704. Epub 2005 Feb 14.
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
8. Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes. Wang C, etal., J Biol Chem. 2011 Feb 25;286(8):6542-53. Epub 2010 Dec 7.
9. The N-terminus of retinol dehydrogenase type 1 signals cytosolic orientation in the microsomal membrane. Wang J, etal., Biochemistry. 2001 Oct 23;40(42):12533-40.
Additional References at PubMed
PMID:8251521   PMID:9407098   PMID:9677409   PMID:10329026   PMID:11876656   PMID:12534290   PMID:15355969   PMID:15489334   PMID:16223484  


Genomics

Comparative Map Data
Rdh16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8765,499,763 - 65,510,304 (+)NCBIGRCr8
mRatBN7.2763,616,711 - 63,625,053 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl763,597,536 - 63,624,124 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx765,505,927 - 65,514,269 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0767,708,217 - 67,716,557 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0767,509,523 - 67,517,833 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0771,058,150 - 71,072,685 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl770,980,422 - 71,072,689 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0771,151,962 - 71,152,405 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,752,257 - 67,766,995 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1767,772,988 - 67,787,725 (+)NCBI
Celera754,092,966 - 54,096,444 (-)NCBICelera
Cytogenetic Map7q22NCBI
RDH16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,951,431 - 56,957,608 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,951,431 - 56,959,374 (-)EnsemblGRCh38hg38GRCh38
GRCh371257,345,215 - 57,351,392 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,631,482 - 55,637,685 (-)NCBINCBI36Build 36hg18NCBI36
Celera1256,999,103 - 57,005,306 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,383,970 - 54,390,173 (-)NCBIHuRef
CHM1_11257,312,965 - 57,319,168 (-)NCBICHM1_1
T2T-CHM13v2.01256,919,300 - 56,925,477 (-)NCBIT2T-CHM13v2.0
Rdh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,595,595 - 127,604,168 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,595,590 - 127,604,166 (+)EnsemblGRCm39 Ensembl
GRCm3810127,759,726 - 127,768,299 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10127,759,721 - 127,768,297 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,196,819 - 127,205,355 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,162,759 - 127,171,245 (+)NCBIMGSCv36mm8
Celera10130,154,374 - 130,162,902 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1075.21NCBI
RDH16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,345,736 - 37,380,367 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,369,988 - 37,377,137 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01231,958,385 - 31,966,319 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,211,691 - 32,219,624 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,212,746 - 32,219,624 (+)Ensemblpanpan1.1panPan2
RDH16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1101,124,322 - 1,134,138 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl101,124,320 - 1,130,453 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha101,188,751 - 1,198,258 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0101,135,298 - 1,144,806 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl101,135,296 - 1,145,453 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1101,112,204 - 1,121,711 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,354,063 - 1,363,571 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,478,831 - 1,488,339 (-)NCBIUU_Cfam_GSD_1.0
LOC101965278
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,669,159 - 57,676,568 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366461,194,547 - 1,200,897 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366461,195,200 - 1,200,778 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100512656
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl522,228,057 - 22,292,434 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1522,277,006 - 22,285,534 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2524,085,801 - 24,094,292 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RDH16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,826,447 - 52,854,731 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,848,488 - 52,854,167 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,118,277 - 193,127,224 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:394
Count of miRNA genes:203
Interacting mature miRNAs:228
Transcripts:ENSRNOT00000037218, ENSRNOT00000051075
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72380760668807606Rat
10053722Scort27Serum corticosterone level QTL 272.410.0083blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)74511390390113903Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72663805771638057Rat
1300127Srn1Serum renin concentration QTL 13.87blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)72417947886817926Rat
10059605Kidm47Kidney mass QTL 472.910.05kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)74913799967614020Rat
1357336Gluco6Glucose level QTL 63.4blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)75170064396700643Rat
1358361Sradr5Stress Responsive Adrenal Weight QTL 55.55adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)731770293110435881Rat
1298525Cm1Cardiac mass QTL 12.7heart mass (VT:0007028)heart wet weight (CMO:0000069)756625161101625161Rat
631513Scl7Serum cholesterol level QTL 74.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)73984590284845902Rat
10755453Coatc12Coat color QTL 120coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)73299870277998702Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)746307490127866166Rat
7411605Foco14Food consumption QTL 1424.10.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)73617876481178764Rat
1300151Bp181Blood pressure QTL 1813.36arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)755498584105834451Rat
1559283Emca4Estrogen-induced mammary cancer QTL 43.7mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)763889858108889858Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)71011291699900612Rat
738030Anxrr8Anxiety related response QTL 84.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)74847504993475049Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631534Lnnr1Liver neoplastic nodule remodeling QTL 13.850.001liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)73617876481178764Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)740540077123682549Rat
70190Mcs6Mammary carcinoma susceptibility QTL 62.29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)72862457565788017Rat
2316947Rf58Renal function QTL 587.8kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)749682832115766396Rat
1298528Bp169Blood pressure QTL 1690.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)762963207107963207Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)72154197786817926Rat
1576303Ept7Estrogen-induced pituitary tumorigenesis QTL 73.7pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)763889858108889858Rat
2316955Stl24Serum triglyceride level QTL 247.1blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)749682832115766396Rat
2316952Pur22Proteinuria QTL 225.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)749682832115766396Rat
2303582Gluco53Glucose level QTL 533blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)74860308793603087Rat
61439Cia8Collagen induced arthritis QTL 85.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)72718291472182914Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 11 43 82 57 60 41 19 41 160 73 74 35 41 19

Sequence


Ensembl Acc Id: ENSRNOT00000037218   ⟹   ENSRNOP00000035423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,597,536 - 63,612,232 (+)Ensembl
Rnor_6.0 Ensembl771,057,911 - 71,072,423 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000051075   ⟹   ENSRNOP00000039311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,604,799 - 63,612,498 (+)Ensembl
Rnor_6.0 Ensembl771,065,197 - 71,072,689 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000077912   ⟹   ENSRNOP00000074126
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,604,885 - 63,624,124 (+)Ensembl
Rnor_6.0 Ensembl770,980,422 - 71,072,072 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097465   ⟹   ENSRNOP00000088842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl763,616,724 - 63,624,124 (+)Ensembl
RefSeq Acc Id: NM_199208   ⟹   NP_954678
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8765,501,964 - 65,510,304 (+)NCBI
mRatBN7.2763,616,711 - 63,625,053 (+)NCBI
Rnor_6.0771,058,150 - 71,072,685 (+)NCBI
Rnor_5.0771,151,962 - 71,152,405 (+)NCBI
RGSC_v3.4767,752,257 - 67,766,995 (+)RGD
Celera754,092,966 - 54,096,444 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063263147   ⟹   XP_063119217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8765,499,763 - 65,502,971 (+)NCBI
RefSeq Acc Id: NP_954678   ⟸   NM_199208
- UniProtKB: P50170 (UniProtKB/Swiss-Prot),   Q6P6V2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000039311   ⟸   ENSRNOT00000051075
Ensembl Acc Id: ENSRNOP00000074126   ⟸   ENSRNOT00000077912
Ensembl Acc Id: ENSRNOP00000035423   ⟸   ENSRNOT00000037218
Ensembl Acc Id: ENSRNOP00000088842   ⟸   ENSRNOT00000097465
RefSeq Acc Id: XP_063119217   ⟸   XM_063263147
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50170-F1-model_v2 AlphaFold P50170 1-317 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695271
Promoter ID:EPDNEW_R5796
Type:multiple initiation site
Name:LOC100365958_1
Description:Rdh2 protein-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0771,065,240 - 71,065,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735050 AgrOrtholog
BioCyc Gene G2FUF-33720 BioCyc
Ensembl Genes ENSRNOG00000029651 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055025879 UniProtKB/Swiss-Prot
  ENSRNOG00060007994 UniProtKB/Swiss-Prot
  ENSRNOG00065016700 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000037218.8 UniProtKB/TrEMBL
  ENSRNOT00000051075.3 UniProtKB/TrEMBL
  ENSRNOT00000077912.2 UniProtKB/TrEMBL
  ENSRNOT00000097465.1 UniProtKB/Swiss-Prot
  ENSRNOT00055044643 UniProtKB/Swiss-Prot
  ENSRNOT00060013203 UniProtKB/Swiss-Prot
  ENSRNOT00065027840 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5599919 IMAGE-MGC_LOAD
  IMAGE:7128686 IMAGE-MGC_LOAD
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:299511 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72262 IMAGE-MGC_LOAD
  MGC:94173 IMAGE-MGC_LOAD
NCBI Gene 299511 ENTREZGENE
PANTHER CIS-RETINOL/3ALPHA HYDROXYSTEROL SHORT-CHAIN DEHYDROGENASE-LIKE PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam adh_short UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rdh16 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029651 RatGTEx
  ENSRNOG00055025879 RatGTEx
  ENSRNOG00060007994 RatGTEx
  ENSRNOG00065016700 RatGTEx
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K7A4_RAT UniProtKB/TrEMBL
  F1LM78_RAT UniProtKB/TrEMBL
  F7FHR5_RAT UniProtKB/TrEMBL
  P50170 ENTREZGENE
  Q6P6V2 ENTREZGENE, UniProtKB/TrEMBL
  RDH16_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-02-19 Rdh16  retinol dehydrogenase 16  Rdh16  retinol dehydrogenase 16 (all-trans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-05-24 Rdh16  retinol dehydrogenase 16 (all-trans)  LOC100361975  retinol dehydrogenase 2-like  Data merged from RGD:2319105 1643240 APPROVED
2012-02-02 Rdh16  retinol dehydrogenase 16 (all-trans)  Rdh2  retinol dehydrogenase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100361975  retinol dehydrogenase 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-08 Rdh2  retinol dehydrogenase 2  RoDHII  retinol dehydrogenase type II (RODH II)  Symbol and Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression highest expression found in liver with lower but detectable expression in kidney, brain, lung and testis 1299624
gene_expression expression is increased 3.7 fold in SHR compared with WKY rats 1357414
gene_other uses holo-cellular retinol-binding protein (CRBP/retinol) as a substrate 1299624