Gene:	Csnk1a1 ( Rattus norvegicus ) casein kinase 1, alpha 1
Description:	splice variant isoforms CKI alpha and CKI alpha L both have casein kinase I activity but display differences in substrate kinetics
Synonyms:	MGC156603;  (details...)
ArrayIDs:	A_44_P103854; 6496477; 6303468; 1374646_at; 6159256; 1369312_a_at; 5649107; 1394689_at; rc_AI235291_at; 5656714; 1389859_at; A_44_P164889; 5971490; U77583_at; rc_AI030738_at; rc_AA955819_at; 6479831; rc_AA955819_g_at; 5908771; 6646665; 5923033; A_43_P12873; 6068936;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CSNK1A1     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Csnk1a1     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Csnk1a1 genome assembly 3.1 18 57613904 - 57636793     Rat Celera Assembly 18 53168136 - 53197926     RGSC genome assembly v3.4 18 57541673 - 57571464     Cytogenetic 18 q12.1 Mus musculus Csnk1a1 Mouse genome assembly build 36.1 18 61715236 - 61747953     Cytogenetic 18 18 D3 Homo sapiens CSNK1A1 human genome assembly 5 148855741 - 148910850     Human genome assembly build 36.2 5 148855038 - 148911200     Cytogenetic 5 q32   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology nucleotide binding,  protein serine/threonine kinase activity,  phosphoprotein binding ...  (details...)
Biological Process	Gene Ontology cell morphogenesis,  biological_process,  protein amino acid phosphorylation (details...)
Cellular Component	Gene Ontology soluble fraction,  cytosol,  cellular_component (details...)
Pathway	Ontology canonical Wnt signaling pathway (details...)
Transcript structure	Note Reference CKI alpha and CKI alpha L are alternatively spliced isoforms 70700
Protein	Note Reference splice variant CKI alpha L contains an insertion within the catalytic site 70700
External Links
Databases	DATABASE ID SOURCE PROSITE: PROTEIN_KINASE_ATP IPI PROSITE: PROTEIN_KINASE_DOM IPI PROSITE: PROTEIN_KINASE_ST IPI UNIPARC: UPI0001B79D6E IPI UNIPARC: UPI000000412B IPI KEGG Report: rno:113927 ENTREZGENE HomoloGene Group ID: 37546 ENTREZGENE Germonline: 71098 Pfam: Pkinase IPI KEGG Pathway: 04310 ENTREZGENE KEGG Pathway: 04340 ENTREZGENE InterPro: Ser/Thr_prot_kinase_AS. IPI InterPro: Protein_kinase_ATP_BS. IPI InterPro: Se/Thr_prot_kinase-like_dom. IPI InterPro: Prot_kinase_cat_dom. IPI InterPro: Kinase-like_dom. IPI IPI: IPI00231832 IPI IPI: IPI00206466 IPI Ensembl Protein: ENSRNOP00000023302 IPI Ensembl Protein: ENSRNOP00000051516 IPI Ensembl Protein: ENSRNOP00000062327 IPI IMAGE_CLONE: IMAGE:8364080 IMAGE-MGC_LOAD Entrez Gene: Csnk1a1 ENTREZGENE MGC_CLONE: MGC:156603 IMAGE-MGC_LOAD UniProt: KC1A_RAT IPI UniProt: KC1A_RAT IPI UniProt: A0JPL2_RAT IPI Ensembl Genes: ENSRNOG00000017106 IPI Superfamily-SCOP: Kinase_like IPI
Sequences	Nucleotide: U77583 Get FASTA Search GEO Profiles Nucleotide: U77582 Get FASTA Search GEO Profiles Nucleotide: BC127486 Get FASTA Search GEO Profiles Nucleotide: NM_053615 Get FASTA Search GEO Profiles Nucleotide: CH473971 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: NP_446067 Get FASTA Protein: EDM14605 Get FASTA Protein: EDM14606 Get FASTA Protein: EDM14607 Get FASTA Protein: EDM14608 Get FASTA Protein: EDM14609 Get FASTA Protein: EDM14610 Get FASTA Protein: EDM14611 Get FASTA Protein: EDM14612 Get FASTA Protein: AAB19228 Get FASTA Protein: AAI27487 Get FASTA Protein: AAB19227 Get FASTA Protein: P97633 Get FASTA (View all 13 Protein Accessions)
Clusters	UniGene: 23810
References
Curated References	7 references in RGD related to Csnk1a1
Other References	4 other references at PubMed related to Csnk1a1
Database Information
RGD ID	71098
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 09-JUL-02: Csnk1a1 casein kinase 1, alpha 1 APPROVED Symbol and Name updated to reflect Human and Mouse nomenclature 70877