Tomm20 (translocase of outer mitochondrial membrane 20) - Rat Genome Database

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Gene: Tomm20 (translocase of outer mitochondrial membrane 20) Rattus norvegicus
Analyze
Symbol: Tomm20
Name: translocase of outer mitochondrial membrane 20
RGD ID: 708467
Description: Enables mitochondrion targeting sequence binding activity. Involved in protein targeting to mitochondrion; response to 3,3',5-triiodo-L-thyronine; and response to muscle activity. Located in mitochondrial outer membrane. Biomarker of muscular atrophy. Orthologous to human TOMM20 (translocase of outer mitochondrial membrane 20); PARTICIPATES IN beta-barrel pathway of mitochondrial protein import; carrier pathway of mitochondrial protein import; presequence pathway of mitochondrial protein import; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC266601; MGC93136; mitochondrial 20 kDa outer membrane protein; mitochondrial import receptor subunit TOM20 homolog; outer mitochondrial membrane receptor rTOM20; outer mitochondrial membrane receptor Tom20; translocase of outer mitochondrial membrane 20 homolog; translocase of outer mitochondrial membrane 20 homolog (yeast)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81971,822,429 - 71,832,420 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1971,822,411 - 71,832,510 (-)EnsemblGRCr8
mRatBN7.21954,925,197 - 54,935,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1954,923,402 - 54,935,198 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1961,715,264 - 61,725,255 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01962,575,165 - 62,585,156 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01964,657,703 - 64,667,694 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01959,863,421 - 59,873,411 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1959,863,421 - 59,873,411 (-)Ensemblrn6Rnor6.0
Rnor_5.01970,530,583 - 70,540,402 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41956,850,851 - 56,863,167 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1954,265,379 - 54,274,601 (-)NCBICelera
RGSC_v3.11956,855,910 - 56,868,227 (-)NCBI
Cytogenetic Map19q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-methyladenine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrolein  (EXP)
acrylonitrile  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atorvastatin calcium  (ISO)
atrazine  (ISO)
bafilomycin A1  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bupivacaine  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CCCP  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cocaine  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
Di-n-octyl phthalate  (ISO)
dibutyl phthalate  (EXP,ISO)
dihydroxyacetone  (EXP)
doxorubicin  (ISO)
enalapril  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
GSK-J4  (ISO)
hydralazine  (ISO)
L-methionine  (ISO)
lactacystin  (ISO)
losartan  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
oleanolic acid  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
pepstatin A  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
propiconazole  (ISO)
pyrroloquinoline quinone  (ISO)
regorafenib  (ISO)
resveratrol  (EXP)
rimonabant  (ISO)
rotenone  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism. Anandatheerthavarada HK, etal., J Biol Chem. 2009 Jun 19;284(25):17352-63. doi: 10.1074/jbc.M109.007492. Epub 2009 Apr 28.
2. Thyroid hormone modifies mitochondrial phenotype by increasing protein import without altering degradation. Craig EE, etal., Am J Physiol. 1998 Dec;275(6 Pt 1):C1508-15.
3. Biogenesis of mitochondrial outer membrane proteins, problems and diseases. Ellenrieder L, etal., Biol Chem. 2015 Oct 1;396(11):1199-213. doi: 10.1515/hsz-2015-0170.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Assembly of beta-barrel proteins in the mitochondrial outer membrane. Hohr AI, etal., Biochim Biophys Acta. 2015 Jan;1853(1):74-88. doi: 10.1016/j.bbamcr.2014.10.006. Epub 2014 Oct 8.
7. Crystallization and preliminary X-ray analysis of mitochondrial presequence receptor Tom20 in complexes with a presequence from aldehyde dehydrogenase. Igura M, etal., Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt 5):514-7. doi: 10.1107/S1744309105011577. Epub 2005 Apr 22.
8. Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70. Iwashita S, etal., J Biochem. 2010 Apr;147(4):581-90. doi: 10.1093/jb/mvp205. Epub 2009 Dec 10.
9. Characterization of the signal that directs Tom20 to the mitochondrial outer membrane. Kanaji S, etal., J Cell Biol. 2000 Oct 16;151(2):277-88.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Unlocking the presequence import pathway. Schulz C, etal., Trends Cell Biol. 2015 May;25(5):265-75. doi: 10.1016/j.tcb.2014.12.001. Epub 2014 Dec 23.
14. Effect of denervation-induced muscle disuse on mitochondrial protein import. Singh K and Hood DA, Am J Physiol Cell Physiol. 2011 Jan;300(1):C138-45. doi: 10.1152/ajpcell.00181.2010. Epub 2010 Oct 13.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
16. Characterization of rat TOM70 as a receptor of the preprotein translocase of the mitochondrial outer membrane. Suzuki H, etal., J Cell Sci 2002 May 1;115(Pt 9):1895-905.
17. Contractile activity-induced adaptations in the mitochondrial protein import system. Takahashi M, etal., Am J Physiol. 1998 May;274(5 Pt 1):C1380-7.
18. Cooperation of protein machineries in mitochondrial protein sorting. Wenz LS, etal., Biochim Biophys Acta. 2015 May;1853(5):1119-29. doi: 10.1016/j.bbamcr.2015.01.012. Epub 2015 Jan 26.
19. Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity. Yano M, etal., J Biol Chem 2004 Mar 12;279(11):10808-13. Epub 2003 Dec 29.
Additional References at PubMed
PMID:10721992   PMID:12925707   PMID:12931191   PMID:14557246   PMID:14651853   PMID:15136728   PMID:16129883   PMID:17948058   PMID:18614015   PMID:20671748   PMID:21173275   PMID:21591667  
PMID:21799113   PMID:23432372   PMID:23455425   PMID:23789093   PMID:23979707   PMID:24191052   PMID:24515348   PMID:25327288   PMID:25997101   PMID:27280685   PMID:31505169   PMID:33657094  


Genomics

Comparative Map Data
Tomm20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81971,822,429 - 71,832,420 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1971,822,411 - 71,832,510 (-)EnsemblGRCr8
mRatBN7.21954,925,197 - 54,935,188 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1954,923,402 - 54,935,198 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1961,715,264 - 61,725,255 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01962,575,165 - 62,585,156 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01964,657,703 - 64,667,694 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01959,863,421 - 59,873,411 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1959,863,421 - 59,873,411 (-)Ensemblrn6Rnor6.0
Rnor_5.01970,530,583 - 70,540,402 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41956,850,851 - 56,863,167 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1954,265,379 - 54,274,601 (-)NCBICelera
RGSC_v3.11956,855,910 - 56,868,227 (-)NCBI
Cytogenetic Map19q12NCBI
TOMM20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381235,109,341 - 235,128,837 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1235,109,341 - 235,128,846 (-)Ensemblhg38GRCh38
GRCh371235,272,656 - 235,292,152 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361233,339,283 - 233,358,754 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341231,598,700 - 231,618,172NCBI
Celera1208,515,476 - 208,534,891 (-)NCBICelera
Cytogenetic Map1q42.3NCBI
HuRef1205,721,246 - 205,740,848 (-)NCBIHuRef
CHM1_11236,544,978 - 236,564,578 (-)NCBICHM1_1
T2T-CHM13v2.01234,501,058 - 234,520,553 (-)NCBIT2T-CHM13v2.0
Tomm20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398127,657,414 - 127,672,671 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8127,657,417 - 127,672,594 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm388126,930,664 - 126,945,921 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8126,930,667 - 126,945,844 (-)Ensemblmm10GRCm38
MGSCv378129,458,450 - 129,469,730 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv368129,820,640 - 129,831,920 (-)NCBIMGSCv36mm8
Celera8131,250,666 - 131,261,945 (-)NCBICelera
Cytogenetic Map8E2NCBI
cM Map874.64NCBI
Tomm20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554924,759,611 - 4,769,847 (+)Ensembl
ChiLan1.0NW_0049554924,759,438 - 4,771,060 (+)NCBIChiLan1.0ChiLan1.0
TOMM20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2114,065,296 - 14,085,234 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1114,276,223 - 14,296,142 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,654,256 - 210,674,157 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11215,672,538 - 215,692,471 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1215,672,544 - 215,692,471 (-)EnsemblpanPan2panpan1.1
TOMM20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.144,785,589 - 4,802,170 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl44,785,584 - 4,801,006 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha44,768,144 - 4,784,739 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.044,807,784 - 4,824,378 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl44,807,831 - 4,825,529 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.144,818,627 - 4,835,209 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.044,936,217 - 4,952,808 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.045,157,946 - 5,174,766 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tomm20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934441,117,944 - 41,129,927 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648417,283,548 - 17,295,157 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648417,283,527 - 17,295,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOMM20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1456,113,192 - 56,127,677 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11456,113,087 - 56,127,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21460,218,706 - 60,233,246 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOMM20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12572,286,666 - 72,304,129 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605574,318,901 - 74,336,764 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tomm20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477515,331,047 - 15,355,206 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462477515,331,214 - 15,355,206 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tomm20
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11746,457,609 - 46,467,433 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:323
Count of miRNA genes:209
Interacting mature miRNAs:240
Transcripts:ENSRNOT00000027088
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194438513474246245Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)193253961574246245Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)196124916174246245Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)193177788874246245Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032907674246245Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)194622677874246245Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19219431774246245Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)193236531174246245Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)194172254674246245Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)193628974246245Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19219431774246245Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191083361874246245Rat

Markers in Region
RH134841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21954,936,547 - 54,936,729 (+)MAPPERmRatBN7.2
Rnor_6.01959,874,771 - 59,874,952NCBIRnor6.0
Rnor_5.01970,541,762 - 70,541,943UniSTSRnor5.0
RGSC_v3.41956,864,527 - 56,864,708UniSTSRGSC3.4
Celera1954,275,961 - 54,276,142UniSTS
Cytogenetic Map19q12UniSTS
RH140946  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21954,936,688 - 54,936,884 (+)MAPPERmRatBN7.2
Rnor_6.01959,874,912 - 59,875,107NCBIRnor6.0
Rnor_5.01970,541,903 - 70,542,098UniSTSRnor5.0
RGSC_v3.41956,864,668 - 56,864,863UniSTSRGSC3.4
Celera1954,276,102 - 54,276,297UniSTS
Cytogenetic Map19q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027088   ⟹   ENSRNOP00000027088
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1971,822,411 - 71,832,436 (-)Ensembl
mRatBN7.2 Ensembl1954,923,402 - 54,935,198 (-)Ensembl
Rnor_6.0 Ensembl1959,863,421 - 59,873,411 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118952   ⟹   ENSRNOP00000092401
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1954,923,402 - 54,935,078 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000133011   ⟹   ENSRNOP00000102437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1971,822,411 - 71,832,510 (-)Ensembl
RefSeq Acc Id: NM_152935   ⟹   NP_690918
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81971,822,429 - 71,832,420 (-)NCBI
mRatBN7.21954,925,197 - 54,935,188 (-)NCBI
Rnor_6.01959,863,421 - 59,873,411 (-)NCBI
Rnor_5.01970,530,583 - 70,540,402 (-)NCBI
RGSC_v3.41956,850,851 - 56,863,167 (-)RGD
Celera1954,265,379 - 54,274,601 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_690918 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB01506 (Get FASTA)   NCBI Sequence Viewer  
  AAH78715 (Get FASTA)   NCBI Sequence Viewer  
  BAA09714 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027088
  ENSRNOP00000027088.2
GenBank Protein Q62760 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_690918   ⟸   NM_152935
- UniProtKB: Q63804 (UniProtKB/Swiss-Prot),   Q62760 (UniProtKB/Swiss-Prot),   O08517 (UniProtKB/Swiss-Prot),   Q6AZ66 (UniProtKB/Swiss-Prot),   A6KJ54 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027088   ⟸   ENSRNOT00000027088
Ensembl Acc Id: ENSRNOP00000092401   ⟸   ENSRNOT00000118952
Ensembl Acc Id: ENSRNOP00000102437   ⟸   ENSRNOT00000133011

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62760-F1-model_v2 AlphaFold Q62760 1-145 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701253
Promoter ID:EPDNEW_R11777
Type:multiple initiation site
Name:Tomm20_1
Description:translocase of outer mitochondrial membrane 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01959,873,418 - 59,873,478EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708467 AgrOrtholog
BioCyc Gene G2FUF-5149 BioCyc
Ensembl Genes ENSRNOG00000019980 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027088 ENTREZGENE
  ENSRNOT00000027088.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.960.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7127457 IMAGE-MGC_LOAD
InterPro MAS20 UniProtKB/Swiss-Prot
  MAS20_rcpt_metazoan UniProtKB/Swiss-Prot
  Tom20_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:266601 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93136 IMAGE-MGC_LOAD
NCBI Gene 266601 ENTREZGENE
PANTHER MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 HOMOLOG UniProtKB/Swiss-Prot
  PTHR12430 UniProtKB/Swiss-Prot
Pfam MAS20 UniProtKB/Swiss-Prot
PhenoGen Tomm20 PhenoGen
PIRSF MAS20_rcpt UniProtKB/Swiss-Prot
PRINTS EUOM20RECPTR UniProtKB/Swiss-Prot
  OM20RECEPTOR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019980 RatGTEx
Superfamily-SCOP SSF47157 UniProtKB/Swiss-Prot
UniProt A0ABK0LCU9_RAT UniProtKB/TrEMBL
  A6KJ54 ENTREZGENE, UniProtKB/TrEMBL
  O08517 ENTREZGENE
  Q62760 ENTREZGENE
  Q63804 ENTREZGENE
  Q6AZ66 ENTREZGENE
  TOM20_RAT UniProtKB/Swiss-Prot
UniProt Secondary O08517 UniProtKB/Swiss-Prot
  Q63804 UniProtKB/Swiss-Prot
  Q6AZ66 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-01 Tomm20  translocase of outer mitochondrial membrane 20  Tomm20  translocase of outer mitochondrial membrane 20 homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tomm20  translocase of outer mitochondrial membrane 20 homolog (yeast)  LOC266601  outer mitochondrial membrane receptor rTOM20  Symbol and Name updated 1299863 APPROVED