Arfgap1 (ARF GTPase activating protein 1) - Rat Genome Database

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Gene: Arfgap1 (ARF GTPase activating protein 1) Rattus norvegicus
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Symbol: Arfgap1
Name: ARF GTPase activating protein 1 (Ensembl:ADP-ribosylation factor GTPase activating protein 1)
RGD ID: 708452
Description: Predicted to enable GTPase activator activity. Predicted to be involved in regulation of ARF protein signal transduction and regulation of endocytosis. Located in Golgi membrane. Orthologous to human ARFGAP1 (ARF GTPase activating protein 1); PARTICIPATES IN Arf family mediated signaling pathway; endocytosis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ADP-ribosylation factor 1 GTPase activating protein; ADP-ribosylation factor 1 GTPase-activating protein; ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase-activating protein 1; ARF GAP 1; Arf GAP1; ARF1 GAP; ARF1-directed GTPase-activating protein; Arf1gap
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,462,125 - 188,477,515 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,465,648 - 188,511,078 (+)EnsemblGRCr8
mRatBN7.23168,084,560 - 168,099,948 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,084,614 - 168,099,933 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,464,963 - 172,479,000 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,424,054 - 181,438,091 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,085,603 - 178,099,635 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,475,847 - 176,490,642 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,475,893 - 176,489,925 (+)Ensemblrn6Rnor6.0
Rnor_5.03180,185,674 - 180,201,025 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,075,313 - 170,100,744 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,486,283 - 164,500,316 (-)NCBICelera
RGSC_v3.13169,981,348 - 170,006,780 (+)NCBI
Cytogenetic Map3q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization. Cukierman E, etal., Science 1995 Dec 22;270(5244):1999-2002.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. ADP-ribosylation factor-directed GTPase-activating protein. Purification and partial characterization. Makler V, etal., J Biol Chem 1995 Mar 10;270(10):5232-7.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. Stafa K, etal., PLoS Genet. 2012;8(2):e1002526. doi: 10.1371/journal.pgen.1002526. Epub 2012 Feb 9.
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Casein kinase I regulates membrane binding by ARF GAP1. Yu S and Roth MG, Mol Biol Cell 2002 Aug;13(8):2559-70.
Additional References at PubMed
PMID:8889548   PMID:9405360   PMID:9733781   PMID:10102276   PMID:11748249   PMID:16316994   PMID:16903783   PMID:17114649   PMID:17253781   PMID:19015319   PMID:19020038   PMID:20211604  
PMID:21499258   PMID:22423108   PMID:24792215   PMID:29476059  


Genomics

Comparative Map Data
Arfgap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83188,462,125 - 188,477,515 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3188,465,648 - 188,511,078 (+)EnsemblGRCr8
mRatBN7.23168,084,560 - 168,099,948 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,084,614 - 168,099,933 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3172,464,963 - 172,479,000 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03181,424,054 - 181,438,091 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,085,603 - 178,099,635 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03176,475,847 - 176,490,642 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3176,475,893 - 176,489,925 (+)Ensemblrn6Rnor6.0
Rnor_5.03180,185,674 - 180,201,025 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43170,075,313 - 170,100,744 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3164,486,283 - 164,500,316 (-)NCBICelera
RGSC_v3.13169,981,348 - 170,006,780 (+)NCBI
Cytogenetic Map3q43NCBI
ARFGAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,272,813 - 63,289,790 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,272,785 - 63,289,790 (+)Ensemblhg38GRCh38
GRCh372061,904,165 - 61,921,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362061,374,610 - 61,391,587 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342061,374,609 - 61,391,587NCBI
Celera2058,581,641 - 58,598,618 (+)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2058,629,588 - 58,646,600 (+)NCBIHuRef
CHM1_12061,805,186 - 61,822,225 (+)NCBICHM1_1
T2T-CHM13v2.02065,078,685 - 65,095,673 (+)NCBIT2T-CHM13v2.0
Arfgap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392180,608,290 - 180,624,319 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2180,609,018 - 180,624,319 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382180,967,225 - 180,982,526 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2180,967,225 - 180,982,526 (+)Ensemblmm10GRCm38
MGSCv372180,701,930 - 180,717,229 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362180,896,677 - 180,911,850 (+)NCBIMGSCv36mm8
Celera2185,053,714 - 185,069,012 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.53NCBI
Arfgap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955528877,073 - 893,484 (-)Ensembl
ChiLan1.0NW_004955528878,837 - 893,427 (-)NCBIChiLan1.0ChiLan1.0
ARFGAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,061,683 - 69,082,400 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,053,689 - 69,071,614 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02059,656,731 - 59,674,802 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12061,197,583 - 61,214,635 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,197,583 - 61,214,635 (+)EnsemblpanPan2panpan1.1
ARFGAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12446,983,944 - 46,995,552 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2446,983,939 - 46,995,548 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2446,167,782 - 46,179,384 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02447,937,705 - 47,949,300 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2447,937,684 - 47,949,305 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12446,952,991 - 46,964,587 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,077,281 - 47,088,873 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02447,833,394 - 47,844,998 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arfgap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,174,022 - 195,187,226 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651410,627,639 - 10,640,869 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493651410,627,700 - 10,641,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARFGAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,380,091 - 62,391,856 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11762,380,060 - 62,391,836 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ARFGAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12918,508 - 936,175 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2917,479 - 936,138 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605048,561,151 - 48,579,371 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arfgap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474128,971,239 - 28,986,717 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474128,971,320 - 28,986,699 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Arfgap1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15158,074,427 - 158,089,957 (+)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:710
Count of miRNA genes:209
Interacting mature miRNAs:245
Transcripts:ENSRNOT00000013900, ENSRNOT00000055038
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1300161Rf10Renal function QTL 103.57renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)3181611379189428310Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat

Markers in Region
AW534395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,094,465 - 168,094,634 (+)MAPPERmRatBN7.2
Rnor_6.03176,485,716 - 176,485,884NCBIRnor6.0
Rnor_5.03180,195,543 - 180,195,711UniSTSRnor5.0
RGSC_v3.43170,085,136 - 170,085,304UniSTSRGSC3.4
Celera3164,490,324 - 164,490,492UniSTS
RH 3.4 Map31532.0UniSTS
Cytogenetic Map3q43UniSTS
RH137730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,092,137 - 168,092,316 (+)MAPPERmRatBN7.2
Rnor_6.03176,483,388 - 176,483,566NCBIRnor6.0
Rnor_5.03180,193,215 - 180,193,393UniSTSRnor5.0
RGSC_v3.43170,082,808 - 170,082,986UniSTSRGSC3.4
Celera3164,492,642 - 164,492,820UniSTS
RH 3.4 Map31531.1UniSTS
Cytogenetic Map3q43UniSTS
RH138664  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23168,099,751 - 168,099,899 (+)MAPPERmRatBN7.2
Rnor_6.03176,491,002 - 176,491,149NCBIRnor6.0
Rnor_5.03180,200,829 - 180,200,976UniSTSRnor5.0
RGSC_v3.43170,101,821 - 170,101,968UniSTSRGSC3.4
Celera3164,485,059 - 164,485,206UniSTS
RH 3.4 Map31530.8UniSTS
Cytogenetic Map3q43UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC135298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ199400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB767714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK838782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV120035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ167810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ167811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232032 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000013900   ⟹   ENSRNOP00000013900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,084,620 - 168,099,418 (+)Ensembl
Rnor_6.0 Ensembl3176,475,893 - 176,489,925 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000055038   ⟹   ENSRNOP00000051916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,084,614 - 168,099,933 (+)Ensembl
Rnor_6.0 Ensembl3176,479,335 - 176,489,594 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082267   ⟹   ENSRNOP00000073451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3168,084,614 - 168,099,933 (+)Ensembl
Rnor_6.0 Ensembl3176,479,335 - 176,489,594 (+)Ensembl
RefSeq Acc Id: NM_145090   ⟹   NP_659558
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,210 - 188,476,242 (+)NCBI
mRatBN7.23168,084,642 - 168,098,675 (+)NCBI
Rnor_6.03176,475,893 - 176,489,925 (+)NCBI
Rnor_5.03180,185,674 - 180,201,025 (+)NCBI
RGSC_v3.43170,075,313 - 170,100,744 (+)RGD
Celera3164,486,283 - 164,500,316 (-)RGD
Sequence:
RefSeq Acc Id: XM_006235731   ⟹   XP_006235793
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,129 - 188,477,515 (+)NCBI
mRatBN7.23168,084,561 - 168,099,948 (+)NCBI
Rnor_6.03176,475,855 - 176,490,642 (+)NCBI
Rnor_5.03180,185,674 - 180,201,025 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235732   ⟹   XP_006235794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,477,515 (+)NCBI
mRatBN7.23168,084,560 - 168,099,948 (+)NCBI
Rnor_6.03176,475,847 - 176,490,642 (+)NCBI
Rnor_5.03180,185,674 - 180,201,025 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104259   ⟹   XP_038960187
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,130 - 188,477,515 (+)NCBI
mRatBN7.23168,084,563 - 168,099,948 (+)NCBI
RefSeq Acc Id: XM_063283084   ⟹   XP_063139154
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283085   ⟹   XP_063139155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283086   ⟹   XP_063139156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,129 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283087   ⟹   XP_063139157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283088   ⟹   XP_063139158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,129 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283089   ⟹   XP_063139159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283090   ⟹   XP_063139160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,129 - 188,477,515 (+)NCBI
RefSeq Acc Id: XM_063283091   ⟹   XP_063139161
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,466,604 - 188,477,515 (+)NCBI
RefSeq Acc Id: XR_010064557
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,475,787 (+)NCBI
RefSeq Acc Id: XR_010064558
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,475,787 (+)NCBI
RefSeq Acc Id: XR_010064559
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,475,787 (+)NCBI
RefSeq Acc Id: XR_010064560
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,475,787 (+)NCBI
RefSeq Acc Id: XR_010064561
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,475,787 (+)NCBI
RefSeq Acc Id: XR_010064562
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83188,462,125 - 188,471,794 (+)NCBI
RefSeq Acc Id: NP_659558   ⟸   NM_145090
- UniProtKB: Q62848 (UniProtKB/Swiss-Prot),   A6KM64 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235794   ⟸   XM_006235732
- Peptide Label: isoform X1
- UniProtKB: Q3S4A4 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235793   ⟸   XM_006235731
- Peptide Label: isoform X1
- UniProtKB: Q3S4A4 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051916   ⟸   ENSRNOT00000055038
Ensembl Acc Id: ENSRNOP00000073451   ⟸   ENSRNOT00000082267
Ensembl Acc Id: ENSRNOP00000013900   ⟸   ENSRNOT00000013900
RefSeq Acc Id: XP_038960187   ⟸   XM_039104259
- Peptide Label: isoform X2
- UniProtKB: Q62848 (UniProtKB/Swiss-Prot),   A6KM64 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139154   ⟸   XM_063283084
- Peptide Label: isoform X3
- UniProtKB: A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139155   ⟸   XM_063283085
- Peptide Label: isoform X4
- UniProtKB: Q3S4A5 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139157   ⟸   XM_063283087
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139159   ⟸   XM_063283089
- Peptide Label: isoform X6
- UniProtKB: A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139156   ⟸   XM_063283086
- Peptide Label: isoform X4
- UniProtKB: Q3S4A5 (UniProtKB/TrEMBL),   A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139158   ⟸   XM_063283088
- Peptide Label: isoform X5
- UniProtKB: A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139160   ⟸   XM_063283090
- Peptide Label: isoform X6
- UniProtKB: A0A0H2UHZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139161   ⟸   XM_063283091
- Peptide Label: isoform X7
Protein Domains
Arf-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62848-F1-model_v2 AlphaFold Q62848 1-415 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692744
Promoter ID:EPDNEW_R3269
Type:initiation region
Name:Arfgap1_1
Description:ADP-ribosylation factor GTPase activating protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3270  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03176,475,865 - 176,475,925EPDNEW
RGD ID:13692745
Promoter ID:EPDNEW_R3270
Type:initiation region
Name:Arfgap1_2
Description:ADP-ribosylation factor GTPase activating protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R3269  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03176,476,333 - 176,476,393EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:708452 AgrOrtholog
BioCyc Gene G2FUF-46310 BioCyc
Ensembl Genes ENSRNOG00000043150 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000013900 ENTREZGENE
  ENSRNOT00000055038 ENTREZGENE
  ENSRNOT00000082267 ENTREZGENE
Gene3D-CATH 1.10.220.150 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7099840 IMAGE-MGC_LOAD
InterPro ARFGAP/RecO UniProtKB/Swiss-Prot
  ArfGAP_dom UniProtKB/Swiss-Prot
  ArfGAP_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:246310 UniProtKB/Swiss-Prot
MGC_CLONE MGC:91464 IMAGE-MGC_LOAD
NCBI Gene 246310 ENTREZGENE
PANTHER ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 UniProtKB/Swiss-Prot
  ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam ArfGap UniProtKB/Swiss-Prot
PhenoGen Arfgap1 PhenoGen
PRINTS REVINTRACTNG UniProtKB/Swiss-Prot
PROSITE ARFGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000043150 RatGTEx
SMART ArfGap UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57863 UniProtKB/Swiss-Prot
UniProt A0A0G2K5J6_RAT UniProtKB/TrEMBL
  A0A0H2UHZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LUW5_RAT UniProtKB/TrEMBL
  A0ABK0LWJ3_RAT UniProtKB/TrEMBL
  A0ABK0M7G7_RAT UniProtKB/TrEMBL
  A6KM64 ENTREZGENE, UniProtKB/TrEMBL
  A6KM65_RAT UniProtKB/TrEMBL
  A6KM66_RAT UniProtKB/TrEMBL
  A6KM67_RAT UniProtKB/TrEMBL
  A6KM68_RAT UniProtKB/TrEMBL
  ARFG1_RAT UniProtKB/Swiss-Prot
  Q3S4A4 ENTREZGENE, UniProtKB/TrEMBL
  Q3S4A5 ENTREZGENE, UniProtKB/TrEMBL
  Q62848 ENTREZGENE
  Q6IRJ8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-11-07 Arfgap1  ARF GTPase activating protein 1  Arfgap1  ADP-ribosylation factor GTPase activating protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Arfgap1  ADP-ribosylation factor GTPase activating protein 1    ADP-ribosylation factor 1 GTPase activating protein  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to Golgi membranes 1299451