Gene:	Cd40lg ( Rattus norvegicus ) CD40 ligand
Description:	CD40 ligand
Synonyms:	tumor necrosis factor (ligand) superfamily, member 5; Tnfsf5; LOC84349;
ArrayIDs:	5963183; AF013985_at; 6695918; 1368800_at; 6057042; 5888676; 6336877; 5693599; A_43_P12781; GE1158018; 6653606; 5663210; 6717193; 6022709; 6665791;  (details...)
Gene Type:	protein-coding
Additional Data
Homologs
Homo sapiens: CD40LG     See the Human gene in context in:     UCSC     NCBI MapViewer
Mus musculus: Cd40lg     See the Mouse gene in context in:     UCSC     NCBI MapViewer
Comparative Map Data Species Symbol Map Name Chr. Position Rattus norvegicus Cd40lg Rat Celera Assembly X 143160596 - 143171765     RGSC genome assembly v3.4 X 141925019 - 141937183     Cytogenetic X q36     genome assembly 3.1 X 141998451 - 142010616 Mus musculus Cd40lg Mouse genome assembly build 36.1 X 54465320 - 54477219     Cytogenetic X X A5 Homo sapiens CD40LG human genome assembly X 135455855 - 135468068     Human genome assembly build 36.2 X 135558002 - 135570215     Cytogenetic X q26   View comparative maps:      NCBI MapViewer
Genome
View:
Browsers:	Select a browser to viewGene (GBrowse)Gene and SNPs (GBrowse)UCSCVCMAPEnsemblNCBIECRVISTAVISTA+UCSC
Annotation
Molecular Function	Gene Ontology CD40 receptor binding,  tumor necrosis factor receptor binding,  cytokine activity ...  (details...)
Biological Process	Gene Ontology regulation of immunoglobulin secretion,  positive regulation of immune response to tumor cell,  positive regulation of interleukin-10 production ...  (details...)
Cellular Component	Gene Ontology extracellular space,  extracellular region,  integral to membrane ...  (details...)
Disease	Ontology Diabetic Nephropathies,  Diabetic Angiopathies,  Diabetes Mellitus ...  (details...)
External Links
Databases	DATABASE ID SOURCE SMART: TNF IPI PROSITE: TNF_2 IPI PROSITE: TNF_1 IPI UNIPARC: UPI00001370B1 IPI KEGG Report: rno:84349 ENTREZGENE HomoloGene Group ID: 56 ENTREZGENE Germonline: 708418 Pfam: TNF IPI KEGG Pathway: 04060 ENTREZGENE KEGG Pathway: 04514 ENTREZGENE KEGG Pathway: 04660 ENTREZGENE InterPro: TNF_5. IPI InterPro: Tumour_necrosis_fac-like. IPI InterPro: TNF_family. IPI IPI: IPI00210301 IPI Ensembl Protein: ENSRNOP00000001162 IPI Gene3D-CATH: Tumour_necrosis_fac-like IPI Entrez Gene: Cd40lg ENTREZGENE PIRSF: TNF_5 IPI UniProt: CD40L_RAT IPI UniProt: A0SZW2_RAT IPI Ensembl Genes: ENSRNOG00000000871 IPI Superfamily-SCOP: TNF_like IPI PRINTS: CD40LIGAND. IPI
Sequences	Nucleotide: CH474106 Get FASTA Search GEO Profiles Nucleotide: AF013985 Get FASTA Search GEO Profiles Nucleotide: NM_053353 Get FASTA Search GEO Profiles Nucleotide: AF116582 Get FASTA Search GEO Profiles Nucleotide: EF066490 Get FASTA Search GEO Profiles (View all 5 Nucleotide Accessions) Protein: ABK59325 Get FASTA Protein: AAD22460 Get FASTA Protein: EDL75129 Get FASTA Protein: AAD09323 Get FASTA Protein: NP_445805 Get FASTA Protein: Q9Z2V2 Get FASTA (View all 6 Protein Accessions)
Clusters	UniGene: 44218
References
Curated References	18 references in RGD related to Cd40lg
Other References	10 other references at PubMed related to Cd40lg
Database Information
RGD ID	708418
History	Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference 30-MAR-06: Cd40lg CD40 ligand Tnfsf5 tumor necrosis factor (ligand) superfamily, member 5 APPROVED Symbol and Name updated 1299863 14-DEC-04: Tnfsf5 tumor necrosis factor (ligand) superfamily, member 5 LOC84349 CD40 ligand APPROVED Symbol and Name updated 1299863