Senp2 Rat Gene (SUMO1/sentrin/SMT3 specific peptidase 2)

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Keyword

Gene:
Senp2 ( Rattus norvegicus )
SUMO1/sentrin/SMT3 specific peptidase 2
Description: binds the GSK-3beta interacting protein Axin; inhibits the Wnt signalling pathway via inhibition of Axin protein complex formation
Synonyms: SUMO/sentrin specific peptidase 2; LOC78973; SUMO/sentrin specific protease 2; Axam; Axin-associating molecule;
ArrayIDs: 6492689; 6063137; 6261979; 6459163; 1369265_at; 5697306; 6424624; 5957779; 1372386_at; 6313659; 6591489; 6416243; 6222639; 5648388; 6271838; A_44_P402479; A_43_P12386; 6171027; 5641120; A_44_P272035; 5873484; 6335048; 5938239; 5724819; 5905484; 5900436; 5916006; 6683830; 6121726; 5825663; 6211787; rc_AA957708_at; 6143655; 5890215; 6616218; 6518085;  (details...)
Gene Type: protein-coding

Additional Data

Homologs
Homo sapiens: SENP2     See the Human gene in context in:     UCSC     NCBI MapViewer

Mus musculus: Senp2     See the Mouse gene in context in:     UCSC     NCBI MapViewer

Comparative Map Data
Species Symbol Map Name Chr. Position
Rattus norvegicus Senp2 genome assembly 3.1 11 81283308 - 81317523
Rat Celera Assembly 11 77846354 - 77880450
RGSC genome assembly v3.4 11 81225720 - 81259934
Cytogenetic 11 q23
Mus musculus Senp2 Mouse genome assembly build 36.1 16 22009582 - 22047949
Cytogenetic 16 16 B1
Homo sapiens SENP2 human genome assembly 3 186786732 - 186831585
Human genome assembly build 36.2 3 186786725 - 186831583
Cytogenetic 3 q27.2

View comparative maps:      NCBI MapViewer

Genome
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Annotation
Molecular Function

Gene Ontology

SUMO-specific protease activity,  protein binding,  peptidase activity ... (details...)
Biological Process

Gene Ontology

modification-dependent protein catabolic process,  protein transport,  transmembrane transport ... (details...)
Cellular Component

Gene Ontology

nucleus,  cytoplasm,  nuclear pore ... (details...)

External Links
Databases
DATABASE ID SOURCE
Ensembl Protein: ENSRNOP00000055120 IPI
Ensembl Protein: ENSRNOP00000002425 IPI
IPI: IPI00780604 IPI
IPI: IPI00189898 IPI
PROSITE: ULP_PROTEASE IPI
Entrez Gene: Senp2 ENTREZGENE
UNIPARC: UPI0000DC197D IPI
UNIPARC: UPI000013584B IPI
KEGG Report: rno:78973 ENTREZGENE
Ensembl Genes: ENSRNOG00000001773 IPI
UniProt: SENP2_RAT IPI
HomoloGene Group ID: 11005 ENTREZGENE
Germonline: 708378
Pfam: Peptidase_C48 IPI
KEGG Pathway: 04310 ENTREZGENE
InterPro: Peptidase_C48. IPI
Sequences
Nucleotide: CH473999 Get FASTA Search GEO Profiles
Nucleotide: AF260129 Get FASTA Search GEO Profiles
Nucleotide: NM_023989 Get FASTA Search GEO Profiles
(View all 3 Nucleotide Accessions)
Protein: NP_076479 Get FASTA
Protein: EDL78045 Get FASTA
Protein: EDL78046 Get FASTA
Protein: AAG34653 Get FASTA
Protein: Q9EQE1 Get FASTA
(View all 5 Protein Accessions)
Clusters
UniGene: 9367

References
Curated References
4 references in RGD related to Senp2

Other References
2 other references at PubMed related to Senp2

Database Information
RGD ID 708378
History

Date Current Symbol Current Name Previous Symbol Previous name Status Description Reference

20-NOV-08: Senp2 SUMO1/sentrin/SMT3 specific peptidase 2 Senp2 SUMO/sentrin specific peptidase 2 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

07-MAR-08: Senp2 SUMO/sentrin specific peptidase 2 Senp2 SUMO/sentrin specific protease 2 APPROVED Nomenclature updated to reflect human and mouse nomenclature 1299863

14-DEC-04: Senp2 SUMO/sentrin specific protease 2 LOC78973 Axin-associating molecule APPROVED Symbol and Name updated 1299863