transient receptor potential cation channel, subfamily V, member 6
RGD ID:
69335
Description:
Enables calcium channel activity and identical protein binding activity. Involved in calcium ion import across plasma membrane and protein homotetramerization. Predicted to be located in apical plasma membrane. Predicted to be part of calcium channel complex. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in hyperparathyroidism. Orthologous to human TRPV6 (transient receptor potential cation channel subfamily V member 6); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
[bisphenol A co-treated with Streptozocin] results in increased expression of TRPV6 mRNA and [Fulvestrant co-treated with bisphenol A] results in increased expression of TRPV6 mRNA
2-aminoethoxydiphenyl borate inhibits the reaction [TRPV6 protein results in increased import of Cadmium] and Cadmium inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium
4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]] more ...
[[USP2 gene mutant form results in increased expression of NHERF4 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium
4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]] more ...
TRPV6 protein promotes the reaction [Capsaicin results in increased abundance of Calcium] and TRPV6 protein promotes the reaction [Capsaicin results in increased expression of BAX protein]
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPV6 mRNA
[Fulvestrant co-treated with bisphenol A] results in increased expression of TRPV6 mRNA and Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of TRPV6 mRNA]
[Lithocholic Acid analog binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA and [Lithocholic Acid binds to and results in increased activity of VDR protein] which results in increased expression of TRPV6 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPV6 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPV6 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of TRPV6 mRNA
4-O-methyl-12-O-tetradecanoylphorbol 13-acetate inhibits the reaction [Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]] and Tamoxifen inhibits the reaction [TRPV6 protein results in increased uptake of Calcium]
[Testosterone co-treated with Calcitriol] results in increased expression of TRPV6 mRNA and Testosterone affects the reaction [Calcitriol results in increased expression of TRPV6 mRNA]
Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel) channels.
