Cdh2 (cadherin 2) - Rat Genome Database

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Gene: Cdh2 (cadherin 2) Rattus norvegicus
Analyze
Symbol: Cdh2
Name: cadherin 2
RGD ID: 69280
Description: Enables beta-catenin binding activity; nitric-oxide synthase binding activity; and protein tyrosine kinase binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; regulation of Rho protein signal transduction; and regulation of myelination. Located in several cellular components, including T-tubule; adherens junction; and fascia adherens. Part of protein-containing complex. Is active in glutamatergic synapse. Human ortholog(s) of this gene implicated in agenesis of corpus callosum, cardiac, ocular, and genital syndrome; arrhythmogenic right ventricular cardiomyopathy; and arrhythmogenic right ventricular dysplasia 14. Orthologous to human CDH2 (cadherin 2); PARTICIPATES IN cadherin mediated signaling pathway; fibroblast growth factor signaling pathway; N-cadherin signaling pathway; INTERACTS WITH (+)-pilocarpine; 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane; 1,3-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cadherin 2 type 1 N-cadherin (neuronal); cadherin 2, type 1, N-cadherin (neuronal); cadherin-2; N-cadherin; neural cadherin
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,051,097 - 8,265,288 (-)NCBIGRCr8
mRatBN7.2187,776,704 - 7,990,934 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,776,704 - 7,990,167 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,020,068 - 8,240,669 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0188,807,745 - 9,028,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,079,330 - 8,299,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0188,146,971 - 8,366,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,146,971 - 8,360,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0187,997,533 - 8,218,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,048,920 - 8,267,974 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1188,048,919 - 8,268,462 (-)NCBI
Celera187,938,006 - 8,155,134 (-)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
Cdh2Ratarrhythmogenic right ventricular cardiomyopathy  ISOCDH2 (Homo sapiens)13524622DNA:missense mutations:cds:c.686A>C(p.Q229P), c.1219G>A (p.D407N)(human)RGD 
Cdh2Ratarrhythmogenic right ventricular cardiomyopathy  ISOCDH2 (Homo sapiens)13524623DNA:mutation:cds:c.1219G>A(p.D407N)(human)RGD 
Cdh2Ratinflammatory bowel disease  ISOCdh2 (Mus musculus)734737 RGD 
Cdh2RatIntestinal Neoplasms  ISOCdh2 (Mus musculus)734737 RGD 
Cdh2RatPulmonary Arterial Hypertension  ISOCDH2 (Homo sapiens)38500244mRNA:increased expression:lungRGD 
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Cdh2RatAgenesis of Corpus Callosum  ISOCDH2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:31585109
Cdh2Ratagenesis of corpus callosum, cardiac, ocular, and genital syndrome  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Agenesis of corpus callosum more ...ClinVarPMID:16199547 more ...
Cdh2Ratarrhythmogenic right ventricular dysplasia 14  ISOCDH2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Cdh2Ratarteriovenous malformations of the brain  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebral arteriovenous malformationClinVarPMID:25741868
Cdh2RatAttention Deficit-Hyperactivity Disorder 8  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Attention deficit-hyperactivity disorder 8ClinVarPMID:25741868 more ...
Cdh2RatAuditory Neuropathy  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Auditory neuropathyClinVarPMID:28492532
Cdh2Ratchromosome 18q deletion syndrome  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Monosomy 18q and deletion 18qClinVarPMID:31690835
Cdh2Ratdilated cardiomyopathy  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary dilated cardiomyopathyClinVarPMID:25741868
Cdh2Ratgenetic disease  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
Cdh2Ratgenetic disease  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Cdh2Ratintellectual disability  ISOCDH2 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
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Cdh2RatAnimal Disease Models  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27811057
Cdh2RatBreast Neoplasms  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27811057
Cdh2RatDisease Progression  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23876460
Cdh2RatMyocardial Ischemia  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16214533
Cdh2RatNeoplasm Invasiveness  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:27811057
Cdh2RatNeoplasm Metastasis  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23876460
Cdh2RatNerve Degeneration  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:12387456
Cdh2Ratstatus epilepticus  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:12125071
Cdh2RatStomach Neoplasms  ISOCDH2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16367923
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Cdh2Ratattention deficit hyperactivity disorder  ISSCdh2 (Mus musculus)13592920OMIM:143465 more ...MouseDO 

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Cdh2Rat(+)-pilocarpine increases expressionEXP 6480464Pilocarpine results in increased expression of CDH2 mRNA and Pilocarpine results in increased expression of CDH2 proteinCTDPMID:12125071 and PMID:12387456
Cdh2Rat(+)-Tetrandrine decreases expressionISOCDH2 (Homo sapiens)6480464tetrandrine results in decreased expression of CDH2 proteinCTDPMID:30549224
Cdh2Rat(-)-epigallocatechin 3-gallate multiple interactionsISOCDH2 (Homo sapiens)64804643-methyladenine inhibits the reaction [epigallocatechin gallate results in decreased expression of CDH2 protein] and TFEB protein affects the reaction [epigallocatechin gallate results in decreased expression of CDH2 protein]CTDPMID:39313106
Cdh2Rat(-)-epigallocatechin 3-gallate decreases expressionISOCDH2 (Homo sapiens)6480464epigallocatechin gallate results in decreased expression of CDH2 proteinCTDPMID:39313106
Cdh2Rat(S)-amphetamine increases expressionISOCdh2 (Mus musculus)6480464Dextroamphetamine results in increased expression of CDH2 mRNACTDPMID:12205029
Cdh2Rat(S)-amphetamine multiple interactionsISOCdh2 (Mus musculus)6480464SOD1 inhibits the reaction [Dextroamphetamine results in increased expression of CDH2 mRNA]CTDPMID:12205029
Cdh2Rat(S)-nicotine multiple interactionsISOCdh2 (Mus musculus)6480464[Nicotine co-treated with Quartz] results in increased expression of CDH2 protein and staurosporine aglycone inhibits the reaction [[Nicotine co-treated with Quartz] results in increased expression of CDH2 protein]CTDPMID:36868510
Cdh2Rat1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane increases expressionISOCDH2 (Homo sapiens)64804642 and 2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CDH2 mRNACTDPMID:16580782
Cdh2Rat1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane multiple interactionsISOCDH2 (Homo sapiens)6480464CDH2 protein affects the reaction [2 and 2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CTNNB1 mRNA]CTDPMID:16580782
Cdh2Rat1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane affects response to substanceEXP 6480464CDH2 protein affects the susceptibility to 2 and 2'-(hydroxynitrosohydrazono)bis-ethanamineCTDPMID:16580782
Cdh2Rat1,2-dichloroethane decreases expressionISOCdh2 (Mus musculus)6480464ethylene dichloride results in decreased expression of CDH2 mRNACTDPMID:28960355
Cdh2Rat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of CDH2 mRNACTDPMID:21983209 and PMID:24140754
Cdh2Rat17alpha-ethynylestradiol multiple interactionsISOCdh2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CDH2 mRNACTDPMID:17942748
Cdh2Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of CDH2 mRNACTDPMID:15834898
Cdh2Rat17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of CDH2 mRNACTDPMID:16079270
Cdh2Rat17beta-estradiol multiple interactionsISOCdh2 (Mus musculus)6480464Estradiol promotes the reaction [FSHB protein results in increased expression of CDH2 mRNA]CTDPMID:8977383
Cdh2Rat17beta-estradiol increases expressionISOCdh2 (Mus musculus)6480464Estradiol results in increased expression of CDH2 mRNACTDPMID:39298647
Cdh2Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of CDH2 mRNACTDPMID:32145629
Cdh2Rat17beta-estradiol increases expressionISOCDH2 (Homo sapiens)6480464Estradiol results in increased expression of CDH2 mRNA and Estradiol results in increased expression of CDH2 proteinCTDPMID:24997338 more ...
Cdh2Rat17beta-estradiol multiple interactionsISOCDH2 (Homo sapiens)64804642-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Estradiol results in increased expression of CDH2 protein] more ...CTDPMID:24997338 more ...

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Biological Process
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Cdh2Ratadherens junction organization involved_inIBAPANTHER:PTN000616280 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratblood vessel morphogenesis acts_upstream_of_or_withinISOCdh2 (Mus musculus)1624291MGI:3522469 PMID:15809310RGDPMID:15809310
Cdh2Ratblood vessel morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratbrain morphogenesis acts_upstream_of_or_withinIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratbrain morphogenesis acts_upstream_of_or_withinISOCdh2 (Mus musculus)1624291MGI:95387 PMID:25100583RGDPMID:25100583
Cdh2Ratcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules  IMP 1626299 RGD 
Cdh2Ratcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules acts_upstream_of_or_withinIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules involved_inIBAMGI:1095414 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules acts_upstream_of_or_withinISOCdh2 (Mus musculus)1624291 PMID:14561752RGDPMID:14561752
Cdh2Ratcell adhesion acts_upstream_of_or_withinISOCdh2 (Mus musculus)1624291 PMID:12738802 and PMID:14657280RGDPMID:12738802 and PMID:14657280
Cdh2Ratcell adhesion involved_inIEAUniProtKB-KW:KW-01301600115GO_REF:0000043UniProtGO_REF:0000043
Cdh2Ratcell adhesion acts_upstream_of_or_withinIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcell adhesion involved_inIEAInterPro:IPR0208941600115GO_REF:0000002InterProGO_REF:0000002
Cdh2Ratcell migration involved_inIBAMGI:2685011 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratcell migration acts_upstream_of_or_withinIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcell migration acts_upstream_of_or_withinISOCdh2 (Mus musculus)1624291 PMID:14561752RGDPMID:14561752
Cdh2Ratcell morphogenesis involved_inIBAMGI:105057 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratcell-cell adhesion  IDA 1626295 RGD 
Cdh2Ratcell-cell adhesion involved_inIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcell-cell adhesion involved_inIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Cdh2Ratadherens junction  IDA 2291902 RGD 
Cdh2Ratadherens junction  IDA 1626295 RGD 
Cdh2Ratadherens junction is_active_inIBAMGI:105057 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratadherens junction located_inISOCdh2 (Mus musculus)1624291 PMID:12052883 more ...RGDPMID:12052883 more ...
Cdh2Ratadherens junction located_inIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratadherens junction located_inIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratadherens junction located_inIEAUniProtKB-SubCell:SL-00091600115GO_REF:0000044UniProtGO_REF:0000044
Cdh2Ratadherens junction located_inISOCDH2 (Homo sapiens)1624291 PMID:19101069 and PMID:24046456RGDPMID:19101069 and PMID:24046456
Cdh2Ratanchoring junction located_inIEAUniProtKB-KW:KW-09651600115GO_REF:0000043UniProtGO_REF:0000043
Cdh2Ratanchoring junction located_inIEAUniProtKB-SubCell:SL-00381600115GO_REF:0000044UniProtGO_REF:0000044
Cdh2Ratapical part of cell is_active_inIBAMGI:88355 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratapical plasma membrane located_inIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratapical plasma membrane located_inISOCdh2 (Mus musculus)1624291 PMID:21947081RGDPMID:21947081
Cdh2Ratapicolateral plasma membrane located_inIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratapicolateral plasma membrane located_inISOCdh2 (Mus musculus)1624291 PMID:29211732RGDPMID:29211732
Cdh2Ratbasolateral plasma membrane located_inIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratbasolateral plasma membrane located_inISOCdh2 (Mus musculus)1624291 PMID:25512490RGDPMID:25512490
Cdh2Ratcatenin complex part_ofIBAMGI:88354 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratcatenin complex part_ofISOCDH2 (Homo sapiens)1624291 PMID:7650039RGDPMID:7650039
Cdh2Ratcatenin complex part_ofIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
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Molecular Function
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Cdh2Ratalpha-catenin binding enablesISOCDH2 (Homo sapiens)1624291UniProtKB:P35221 and PMID:7650039RGDPMID:7650039
Cdh2Ratalpha-catenin binding enablesIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratbeta-catenin binding enablesISOCDH2 (Homo sapiens)1624291UniProtKB:P35222 and PMID:19830702RGDPMID:19830702
Cdh2Ratbeta-catenin binding  IPICtnnb1 (Rattus norvegicus)1626295 RGD 
Cdh2Ratbeta-catenin binding enablesIBAMGI:88354 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratbeta-catenin binding enablesIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcadherin binding enablesIBAMGI:107433 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Cdh2Ratcalcium ion binding enablesISOCdh2 (Mus musculus)1624291 PMID:9655503RGDPMID:9655503
Cdh2Ratcalcium ion binding enablesIEAInterPro:IPR000233 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Cdh2Ratcalcium ion binding enablesIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratcalcium ion binding enablesIEAUniRule:UR0004134501600115GO_REF:0000104UniProtGO_REF:0000104
Cdh2Ratcalcium ion binding enablesISSUniProtKB:P151161600115GO_REF:0000024UniProtGO_REF:0000024
Cdh2Ratenzyme binding enablesISOCdh2 (Mus musculus)1624291UniProtKB:Q9R0S2 and PMID:24952463RGDPMID:24952463
Cdh2Ratenzyme binding enablesIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratgamma-catenin binding enablesIEAUniProtKB:P19022 and ensembl:ENSP000002691411600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratgamma-catenin binding enablesISOCDH2 (Homo sapiens)1624291UniProtKB:P14923 and PMID:7650039RGDPMID:7650039
Cdh2Ratidentical protein binding enablesIEAUniProtKB:P15116 and ensembl:ENSMUSP000000251661600115GO_REF:0000107EnsemblGO_REF:0000107
Cdh2Ratidentical protein binding enablesISOCdh2 (Mus musculus)1624291UniProtKB:P15116 more ...RGDPMID:20190754 more ...
Cdh2Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Cdh2Ratnitric-oxide synthase binding  IPINos2 (Rattus norvegicus)7777144 RGD 
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RGD Manual Annotations


  
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Cdh2Ratcadherin mediated signaling pathway  IMP 1582675 RGD 

Imported Annotations - KEGG (archival)

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Cdh2Ratarrhythmogenic right ventricular cardiomyopathy pathway  IEA 6907045 KEGGrno:05412

Imported Annotations - PID (archival)

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Cdh2Ratfibroblast growth factor signaling pathway  ISOCDH2 (Homo sapiens)6484113 PIDPID:200220
Cdh2RatN-cadherin signaling pathway  ISOCDH2 (Homo sapiens)6484113 PIDPID:200209

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Reference Title
Reference Citation
1. Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. Bakkaloglu B, etal., Am J Hum Genet. 2008 Jan;82(1):165-73. doi: 10.1016/j.ajhg.2007.09.017.
2. Increasing numbers of synaptic puncta during late-phase LTP: N-cadherin is synthesized, recruited to synaptic sites, and required for potentiation. Bozdagi O, etal., Neuron. 2000 Oct;28(1):245-59.
3. Fer kinase/FerT and adherens junction dynamics in the testis: an in vitro and in vivo study. Chen YM, etal., Biol Reprod. 2003 Aug;69(2):656-72. Epub 2003 Apr 16.
4. Rat testicular N-cadherin: its complementary deoxyribonucleic acid cloning and regulation. Chung SS, etal., Endocrinology 1998 Apr;139(4):1853-62.
5. [Dynamic assembly of intercalated disc during postnatal development in the rat myocardium]. Dou JP, etal., Sheng Li Xue Bao. 2014 Oct 25;66(5):569-74.
6. Differential regulation of cadherins and catenins during axonal reorganization in the adult rat CNS. Fasen K, etal., J Neuropathol Exp Neurol 2002 Oct;61(10):903-13.
7. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
8. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
9. Association of an A-kinase-anchoring protein signaling scaffold with cadherin adhesion molecules in neurons and epithelial cells. Gorski JA, etal., Mol Biol Cell. 2005 Aug;16(8):3574-90. Epub 2005 Jun 1.
10. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Hermiston ML and Gordon JI, Science 1995 Nov 17;270(5239):1203-7.
11. N-cadherin in adult rat cardiomyocytes in culture. II. Spatio-temporal appearance of proteins involved in cell-cell contact and communication. Formation of two distinct N-cadherin/catenin complexes. Hertig CM, etal., J Cell Sci. 1996 Jan;109 ( Pt 1):11-20.
12. Multiple cadherin superfamily members with unique expression profiles are produced in rat testis. Johnson KJ, etal., Endocrinology 2000 Feb;141(2):675-83.
13. N-cadherin upregulation and function in response of smooth muscle cells to arterial injury. Jones M, etal., Arterioscler Thromb Vasc Biol 2002 Dec 1;22(12):1972-7.
14. Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase. Kwon YT, etal., Curr Biol. 2000 Apr 6;10(7):363-72.
15. Is the cadherin/catenin complex a functional unit of cell-cell actin-based adherens junctions in the rat testis? Lee NP, etal., Biol Reprod. 2003 Feb;68(2):489-508.
16. Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/beta-catenin (CATNB) signaling pathway: an in vitro and in vivo study. Lee NP, etal., Biol Reprod. 2005 Sep;73(3):458-71. Epub 2005 Apr 27.
17. Ginkgolic acid (GA) suppresses gastric cancer growth by inducing apoptosis and suppressing STAT3/JAK2 signaling regulated by ROS. Liang JR and Yang H, Biomed Pharmacother. 2020 May;125:109585. doi: 10.1016/j.biopha.2019.109585. Epub 2020 Feb 25.
18. N-cadherin signals through Rac1 determine the localization of connexin 43 in cardiac myocytes. Matsuda T, etal., J Mol Cell Cardiol. 2006 Apr;40(4):495-502. Epub 2006 Mar 2.
19. Identification of Cadherin 2 (CDH2) Mutations in Arrhythmogenic Right Ventricular Cardiomyopathy. Mayosi BM, etal., Circ Cardiovasc Genet. 2017 Apr;10(2). pii: CIRCGENETICS.116.001605. doi: 10.1161/CIRCGENETICS.116.001605.
20. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
1 to 20 of 39 rows
PMID:7650039   PMID:8270638   PMID:9531566   PMID:9655503   PMID:11732910   PMID:12052883   PMID:12203715   PMID:12695331   PMID:12738802   PMID:14561752   PMID:14622577   PMID:14657280  
PMID:15383621   PMID:15389538   PMID:15569714   PMID:15691707   PMID:15741167   PMID:15750591   PMID:15809310   PMID:16580782   PMID:16831887   PMID:16886205   PMID:16892058   PMID:16955247  
PMID:16973135   PMID:17028923   PMID:17188238   PMID:17884088   PMID:17959753   PMID:17988630   PMID:18064706   PMID:18067145   PMID:18239929   PMID:18617695   PMID:19075000   PMID:19101069  
PMID:19377287   PMID:19546590   PMID:19830702   PMID:20160094   PMID:20190754   PMID:20333303   PMID:20457910   PMID:20534458   PMID:20623533   PMID:20638445   PMID:20668183   PMID:20848607  
PMID:20881055   PMID:21056983   PMID:21250828   PMID:21257918   PMID:21296051   PMID:21300292   PMID:21414924   PMID:21423176   PMID:21520058   PMID:21572446   PMID:21720156   PMID:21720765  
PMID:21947081   PMID:22199283   PMID:22328515   PMID:22354041   PMID:22467863   PMID:22489706   PMID:22698587   PMID:22735489   PMID:22871113   PMID:23271561   PMID:23292232   PMID:23376485  
PMID:23392350   PMID:24046456   PMID:24223993   PMID:24338362   PMID:24412534   PMID:24891510   PMID:24952463   PMID:25100583   PMID:25232112   PMID:25512490   PMID:25724647   PMID:26187182  
PMID:26345922   PMID:26403541   PMID:26545901   PMID:27559042   PMID:27816814   PMID:28008617   PMID:28169360   PMID:28213972   PMID:28641114   PMID:29131030   PMID:29133434   PMID:29238079  
PMID:29257288   PMID:29768261   PMID:35352799   PMID:37654026   PMID:38127465   PMID:38169592  



Cdh2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8188,051,097 - 8,265,288 (-)NCBIGRCr8
mRatBN7.2187,776,704 - 7,990,934 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl187,776,704 - 7,990,167 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx188,020,068 - 8,240,669 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0188,807,745 - 9,028,345 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0188,079,330 - 8,299,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0188,146,971 - 8,366,037 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl188,146,971 - 8,360,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0187,997,533 - 8,218,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4188,048,920 - 8,267,974 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1188,048,919 - 8,268,462 (-)NCBI
Celera187,938,006 - 8,155,134 (-)NCBICelera
Cytogenetic Map18p13NCBI
CDH2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381827,932,879 - 28,177,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1827,932,879 - 28,177,946 (-)EnsemblGRCh38hg38GRCh38
GRCh371825,530,930 - 25,757,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361823,784,933 - 24,011,189 (-)NCBINCBI36Build 36hg18NCBI36
Build 341823,784,933 - 24,011,189NCBI
Celera1822,342,317 - 22,568,868 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
HuRef1822,383,072 - 22,579,896 (-)NCBIHuRef
CHM1_11825,458,398 - 25,684,881 (-)NCBICHM1_1
T2T-CHM13v2.01828,127,759 - 28,372,130 (-)NCBIT2T-CHM13v2.0
Cdh2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391816,721,934 - 16,942,303 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1816,721,934 - 16,942,303 (-)EnsemblGRCm39 Ensembl
GRCm381816,588,877 - 16,809,246 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1816,588,877 - 16,809,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv371816,747,386 - 16,967,558 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361816,732,027 - 16,952,264 (-)NCBIMGSCv36mm8
Celera1817,099,283 - 17,328,154 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map1810.1NCBI
Cdh2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540215,831,110 - 16,049,890 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540215,829,895 - 16,049,874 (-)NCBIChiLan1.0ChiLan1.0
CDH2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21745,382,669 - 45,608,715 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11831,075,259 - 31,301,025 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01821,210,001 - 21,435,919 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11824,812,019 - 25,008,249 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1824,812,019 - 25,008,325 (-)Ensemblpanpan1.1panPan2
CDH2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1760,736,760 - 60,950,477 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl760,736,760 - 60,951,034 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha760,142,523 - 60,355,795 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0760,754,899 - 60,968,628 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl760,754,774 - 60,968,438 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1760,431,048 - 60,644,193 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0760,442,612 - 60,655,854 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0760,744,933 - 60,958,801 (+)NCBIUU_Cfam_GSD_1.0
Cdh2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494456,749,166 - 56,930,675 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365506,886,706 - 6,945,056 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365506,885,484 - 7,067,001 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6112,396,721 - 112,628,432 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16112,396,713 - 112,629,073 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26105,317,507 - 105,518,900 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDH2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11852,426,381 - 52,652,986 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1852,426,077 - 52,654,828 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605027,147,394 - 27,374,174 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247704,334,202 - 4,545,470 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247704,333,643 - 4,540,817 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Cdh2
1543 total Variants

Predicted Target Of
Summary Value
Count of predictions:156
Count of miRNA genes:109
Interacting mature miRNAs:132
Transcripts:ENSRNOT00000021170
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 15 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2301409Cm70Cardiac mass QTL 700.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)18679125112205285Rat
12904716Am21Aortic mass QTL 210.005aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)18679125112205285Rat
8552968Pigfal19Plasma insulin-like growth factor 1 level QTL 1911.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)18125758124Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
12904714Cm131Cardiac mass QTL 1310.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)18679125112205285Rat
1641910Colcr3Colorectal carcinoma resistance QTL 35.020.000007intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)18224947722066430Rat
12904715Cm132Cardiac mass QTL 1320.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)18679125112205285Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat

1 to 10 of 15 rows
D18Got6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,939,002 - 7,939,178 (+)MAPPERmRatBN7.2
Rnor_6.0188,309,243 - 8,309,418NCBIRnor6.0
Rnor_5.0188,161,224 - 8,161,399UniSTSRnor5.0
RGSC_v3.4188,211,177 - 8,211,405RGDRGSC3.4
RGSC_v3.4188,211,180 - 8,211,355UniSTSRGSC3.4
RGSC_v3.1188,211,180 - 8,211,355RGD
Celera188,099,385 - 8,099,560UniSTS
RH 3.4 Map1866.1RGD
RH 3.4 Map1866.1UniSTS
Cytogenetic Map18p13UniSTS
D18Chm84  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,866,120 - 7,866,271 (+)MAPPERmRatBN7.2
Rnor_6.0188,236,422 - 8,236,572NCBIRnor6.0
Rnor_5.0188,088,405 - 8,088,555UniSTSRnor5.0
RGSC_v3.4188,138,359 - 8,138,509UniSTSRGSC3.4
Celera188,026,453 - 8,026,603UniSTS
Cytogenetic Map18p13UniSTS
D18Wox24  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8188,051,280 - 8,051,437 (+)Marker Load Pipeline
mRatBN7.2187,776,887 - 7,777,044 (+)MAPPERmRatBN7.2
Rnor_6.0188,147,155 - 8,147,311NCBIRnor6.0
Rnor_5.0187,997,717 - 7,997,873UniSTSRnor5.0
RGSC_v3.4188,049,104 - 8,049,260UniSTSRGSC3.4
Cytogenetic Map18p13UniSTS
RH130775  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,777,618 - 7,777,813 (+)MAPPERmRatBN7.2
Rnor_6.0188,147,886 - 8,148,080NCBIRnor6.0
Rnor_5.0187,998,448 - 7,998,642UniSTSRnor5.0
RGSC_v3.4188,049,835 - 8,050,029UniSTSRGSC3.4
Celera187,938,903 - 7,939,097UniSTS
RH 3.4 Map1868.0UniSTS
Cytogenetic Map18p13UniSTS
BF387008  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,859,971 - 7,860,169 (+)MAPPERmRatBN7.2
Rnor_6.0188,230,273 - 8,230,470NCBIRnor6.0
Rnor_5.0188,082,256 - 8,082,453UniSTSRnor5.0
RGSC_v3.4188,132,210 - 8,132,407UniSTSRGSC3.4
Celera188,020,304 - 8,020,501UniSTS
RH 3.4 Map1882.31UniSTS
Cytogenetic Map18p13UniSTS
BF396900  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,932,939 - 7,933,165 (+)MAPPERmRatBN7.2
Rnor_6.0188,303,180 - 8,303,405NCBIRnor6.0
Rnor_5.0188,155,161 - 8,155,386UniSTSRnor5.0
RGSC_v3.4188,205,117 - 8,205,342UniSTSRGSC3.4
Celera188,093,321 - 8,093,546UniSTS
RH 3.4 Map1866.41UniSTS
Cytogenetic Map18p13UniSTS
AU046659  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,895,010 - 7,895,134 (+)MAPPERmRatBN7.2
Rnor_6.0188,265,309 - 8,265,435NCBIRnor6.0
Rnor_5.0188,117,292 - 8,117,418UniSTSRnor5.0
RGSC_v3.4188,167,246 - 8,167,372UniSTSRGSC3.4
Cytogenetic Map18p13UniSTS
RH134928  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8188,230,794 - 8,230,985 (+)Marker Load Pipeline
mRatBN7.2187,956,439 - 7,956,630 (+)MAPPERmRatBN7.2
Rnor_6.0188,326,678 - 8,326,868NCBIRnor6.0
Rnor_5.0188,178,659 - 8,178,849UniSTSRnor5.0
RGSC_v3.4188,228,615 - 8,228,805UniSTSRGSC3.4
Celera188,115,783 - 8,115,973UniSTS
RH 3.4 Map1868.0UniSTS
Cytogenetic Map18p13UniSTS
REN16027  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2187,810,266 - 7,810,521 (+)MAPPERmRatBN7.2
Rnor_6.0188,180,549 - 8,180,803NCBIRnor6.0
Rnor_5.0188,031,420 - 8,031,674UniSTSRnor5.0
RGSC_v3.4188,082,486 - 8,082,740UniSTSRGSC3.4
Celera187,971,154 - 7,971,408UniSTS
Cytogenetic Map18p13UniSTS
UniSTS:498368  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8188,051,156 - 8,051,825 (+)Marker Load Pipeline
mRatBN7.2187,776,763 - 7,777,432 (+)MAPPERmRatBN7.2
Rnor_6.0188,147,031 - 8,147,699NCBIRnor6.0
Rnor_5.0187,997,593 - 7,998,261UniSTSRnor5.0
RGSC_v3.4188,048,980 - 8,049,648UniSTSRGSC3.4
Celera187,938,066 - 7,938,716UniSTS
Cytogenetic Map18p13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000021170   ⟹   ENSRNOP00000021170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl187,776,704 - 7,990,167 (-)Ensembl
Rnor_6.0 Ensembl188,146,971 - 8,360,684 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108729   ⟹   ENSRNOP00000084692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl187,776,704 - 7,893,134 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115561   ⟹   ENSRNOP00000083478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl187,776,704 - 7,857,840 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118601   ⟹   ENSRNOP00000091203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl187,776,704 - 7,957,490 (-)Ensembl
RefSeq Acc Id: NM_031333   ⟹   NP_112623
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8188,051,097 - 8,265,288 (-)NCBI
mRatBN7.2187,776,704 - 7,990,934 (-)NCBI
Rnor_6.0188,146,971 - 8,366,037 (-)NCBI
Rnor_5.0187,997,533 - 8,218,018 (-)NCBI
RGSC_v3.4188,048,920 - 8,267,974 (-)RGD
Celera187,938,006 - 8,155,134 (-)RGD
Sequence:
Protein RefSeqs NP_112623 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC83818 (Get FASTA)   NCBI Sequence Viewer  
  AAF87057 (Get FASTA)   NCBI Sequence Viewer  
  BAA84919 (Get FASTA)   NCBI Sequence Viewer  
  EDL76077 (Get FASTA)   NCBI Sequence Viewer  
  EDL76078 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021170
GenBank Protein Q9Z1Y3 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112623   ⟸   NM_031333
- Peptide Label: precursor
- UniProtKB: Q9Z1Y3 (UniProtKB/Swiss-Prot),   Q9R0T5 (UniProtKB/Swiss-Prot),   G3V803 (UniProtKB/TrEMBL),   A6J2E5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021170   ⟸   ENSRNOT00000021170
Ensembl Acc Id: ENSRNOP00000083478   ⟸   ENSRNOT00000115561
Ensembl Acc Id: ENSRNOP00000091203   ⟸   ENSRNOT00000118601
Ensembl Acc Id: ENSRNOP00000084692   ⟸   ENSRNOT00000108729
Cadherin

Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1Y3-F1-model_v2 AlphaFold Q9Z1Y3 1-906 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13700649
Promoter ID:EPDNEW_R11173
Type:multiple initiation site
Name:Cdh2_1
Description:cadherin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0188,360,413 - 8,360,473EPDNEW


1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-8263 BioCyc
Ensembl Genes ENSRNOG00000015602 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000021170 ENTREZGENE
Gene3D-CATH 4.10.900.10 UniProtKB/Swiss-Prot
  Cadherins UniProtKB/Swiss-Prot
InterPro Cadherin UniProtKB/Swiss-Prot
  Cadherin-like_dom UniProtKB/Swiss-Prot
  Cadherin-like_sf UniProtKB/Swiss-Prot
  Cadherin_CS UniProtKB/Swiss-Prot
  Cadherin_cytoplasmic-dom UniProtKB/Swiss-Prot
  Cadherin_pro_dom UniProtKB/Swiss-Prot
  Catenin_binding_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:83501 UniProtKB/Swiss-Prot
NCBI Gene 83501 ENTREZGENE
PANTHER PTHR24027 UniProtKB/Swiss-Prot
  PTHR24027:SF79 UniProtKB/Swiss-Prot
Pfam Cadherin UniProtKB/Swiss-Prot
  Cadherin_C UniProtKB/Swiss-Prot
  Cadherin_pro UniProtKB/Swiss-Prot
PhenoGen Cdh2 PhenoGen
PRINTS CADHERIN UniProtKB/Swiss-Prot
  DESMOCOLLIN UniProtKB/Swiss-Prot
PROSITE CADHERIN_1 UniProtKB/Swiss-Prot
  CADHERIN_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015602 RatGTEx
SMART Cadherin_pro UniProtKB/Swiss-Prot
  SM00112 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49313 UniProtKB/Swiss-Prot
TIGR TC218644
UniProt A0A8I6A028_RAT UniProtKB/TrEMBL
  A0A8I6A049_RAT UniProtKB/TrEMBL
  A0A8I6ABL6_RAT UniProtKB/TrEMBL
  A6J2E5 ENTREZGENE, UniProtKB/TrEMBL
  CADH2_RAT UniProtKB/Swiss-Prot
  G3V803 ENTREZGENE, UniProtKB/TrEMBL
  Q9R0T5 ENTREZGENE
  Q9Z1Y3 ENTREZGENE
UniProt Secondary Q9R0T5 UniProtKB/Swiss-Prot
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Cdh2  cadherin 2      Name updated 70584 APPROVED

Note Type Note Reference
gene_disease increased expression occurs after balloon catheter injury of the carotid artery 68759
gene_process may be involved in facilitating germ cell migration during spermatogenesis 68761